obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 1 - 10 of 343 in total
Gene ID Gene Symbol Description Source
19 ABCA1 ATP binding cassette subfamily A member 1
32 ACACB acetyl-CoA carboxylase beta
38 ACAT1 acetyl-CoA acetyltransferase 1
51 ACOX1 acyl-CoA oxidase 1
123 PLIN2 perilipin 2
133 ADM adrenomedullin
134 ADORA1 adenosine A1 receptor
154 ADRB2 adrenoceptor beta 2
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
Displaying entries 1 - 10 of 241 in total
Gene ID Gene Symbol Description Source
11303 Abca1 ATP-binding cassette, sub-family A member 1
11421 Ace angiotensin I converting enzyme
11450 Adipoq adiponectin, C1Q and collagen domain containing
11520 Plin2 perilipin 2
11537 Cfd complement factor D
11539 Adora1 adenosine A1 receptor
11555 Adrb2 adrenergic receptor, beta 2
11556 Adrb3 adrenergic receptor, beta 3
11596 Ager advanced glycosylation end product-specific receptor
11625 Ahsg alpha-2-HS-glycoprotein
Displaying entries 141 - 150 of 151 in total
Gene ID Gene Symbol Description Source
296851 Pon2 paraoxonase 2
297508 Nampt nicotinamide phosphoribosyltransferase
308912 Dchs1 dachsous cadherin-related 1
310378 Nnt nicotinamide nucleotide transhydrogenase
360406 Ptprf protein tyrosine phosphatase, receptor type, F
360687 Cadm2 cell adhesion molecule 2
361618 Stim1 stromal interaction molecule 1
361676 Pnpla2 patatin-like phospholipase domain containing 2
363517 Plxnb3 plexin B3
497840 Cps1 carbamoyl-phosphate synthase 1
Displaying entries 41 - 43 of 43 in total
Gene ID Gene Symbol Description Source
43766 PlexB Plexin B
44643 Cnx99A Calnexin 99A
117364 Hex-t1 Hexokinase testis 1
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 51 in total
Gene ID Gene Symbol Description Source
171782 abt-2 ABC transporter domain-containing protein
171994 lin-44 Abnormal cell lineage protein 44
171999 poml-2 Arylesterase
173169 eif-6 Eukaryotic translation initiation factor 6
173399 cwn-1 Protein Wnt-1
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175201 stim-1 Stromal interaction molecule 1
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
Displaying entries 11 - 20 of 29 in total
Gene ID Gene Symbol Description Source
852128 EMI2 putative glucokinase
852276 SLA1 cytoskeletal protein-binding protein SLA1
852543 VVS1 Vvs1p
852639 HXK2 hexokinase 2
852667 POX1 acyl-CoA oxidase
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854080 YOL075C uncharacterized protein
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
9672 SDC3 syndecan 3

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Last updated: December 9, 2024