TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
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- ALK5
- ARH12
- ARHA
- ARHGEF18
- CGN
- F11R
- FKBP1
- FKBP12
- FKBP1A
- JAM1
- JCAM
- KIAA0521
- KIAA1319
- KIAA1625
- PAR3
- PAR3A
- PAR6A
- PARD3
- PARD6A
- PKC2
- PRKCZ
- RHO12
- RHOA
- RPS27A
- SKR4
- SMURF1
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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Homo sapiens (human)
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TGFBR3 regulates TGF-beta signaling
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- ALK5
- ARB2
- ARR1
- ARR2
- ARRB1
- ARRB2
- C19orf3
- GIPC
- GIPC1
- RGS19IP1
- SKR4
- TGFB
- TGFB1
- TGFB2
- TGFBR1
- TGFBR2
- TGFBR3
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Homo sapiens (human)
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ASP-3026-resistant ALK mutants
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Homo sapiens (human)
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NVP-TAE684-resistant ALK mutants
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Homo sapiens (human)
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brigatinib-resistant ALK mutants
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Homo sapiens (human)
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lorlatinib-resistant ALK mutants
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Homo sapiens (human)
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alectinib-resistant ALK mutants
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Homo sapiens (human)
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ceritinib-resistant ALK mutants
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Homo sapiens (human)
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crizotinib-resistant ALK mutants
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Homo sapiens (human)
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MDK and PTN in ALK signaling
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- ALK
- HBNF1
- HTPZP2
- MDK
- MK1
- NEGF1
- NEGF2
- PTN
- PTPRZ
- PTPRZ1
- PTPRZ2
- PTPZ
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Homo sapiens (human)
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ALK mutants bind TKIs
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- ALK
- BCL11A
- BIRC6
- C2orf2
- CLH17
- CLTC
- CLTCL2
- CTIP1
- EIF2AK3
- EMAPL4
- EML4
- EVI9
- FN
- FN1
- HIP1
- KIAA0034
- KIAA1289
- KIAA1809
- NPM
- NPM1
- PEK
- PERK
- PKR1
- PP2CB
- PPM1B
- PRKAR1
- PRKAR1A
- STRN
- TSE1
- ZNF856
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Homo sapiens (human)
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Signaling by ALK fusions and activated point mutants
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- ALK
- ALO17
- APRF
- ASH
- ATIC
- BCL11A
- BCL2L3
- BIRC6
- C17orf27
- C2orf2
- C2orf44
- CAP20
- CARS
- CARS1
- CDKN1
- CDKN1A
- CIP1
- CLH17
- CLTC
- CLTCL2
- CTIP1
- DCTN1
- EEF1G
- EF1G
- EIF2AK3
- EMAPL4
- EML4
- EVI9
- FBX20
- FBXO20
- FN
- FN1
- FRS2
- FRS3
- GCC2
- GRB1
- GRB2
- HIP1
- IL10
- IL22
- ILTIF
- IRS1
- JNK1
- JNK2
- JUN
- KIAA0034
- KIAA0336
- KIAA0858
- KIAA0905
- KIAA1230
- KIAA1289
- KIAA1398
- KIAA1554
- KIAA1618
- KIAA1809
- KIF5B
- KLC
- KLC1
- KNS
- KNS1
- KNS2
- LMO7
- MAPK8
- MAPK9
- MCL1
- MDA6
- MDM2
- MSN
- MYH9
- MYSTR
- NPM
- NPM1
- NUP358
- ORCA
- OSIL
- P53
- PEK
- PERK
- PIC1
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PKR1
- PLC1
- PLCG1
- PP2CB
- PPFIBP1
- PPM1B
- PRKAR1
- PRKAR1A
- PRKM8
- PRKM9
- PURH
- RANBP2
- RANBP2L4
- RNF213
- RPS27A
- RRBP1
- SAPK1
- SAPK1A
- SAPK1C
- SDI1
- SEC31A
- SEC31L1
- SQSTM1
- STAT1
- STAT3
- STRN
- TFG
- TP53
- TPM3
- TPM4
- TPR
- TSE1
- TYK2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- VCL
- WAF1
- WDCP
- ZCYTO18
- ZNF856
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Homo sapiens (human)
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Signaling by ALK
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- ALK
- ALKAL1
- ALKAL2
- APRF
- BHLHE37
- BHLHE39
- FAM150A
- FAM150B
- FRS2
- GRB1
- HBNF1
- HCP
- IRS1
- JAK3
- MDK
- MK1
- MYC
- MYCN
- NEGF1
- NEGF2
- NMYC
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PLC1
- PLCG1
- PTN
- PTP1C
- PTPN6
- STAT3
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Homo sapiens (human)
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Defective ALG9 causes CDG-1l
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Homo sapiens (human)
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Defective ALG6 causes CDG-1c
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Homo sapiens (human)
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Defective ALG3 causes CDG-1d
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Homo sapiens (human)
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Defective ALG14 causes ALG14-CMS
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- ALG13
- ALG14
- CXorf45
- GLT28D1
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Homo sapiens (human)
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Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
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- ALG1
- ALG10
- ALG10A
- ALG10B
- ALG11
- ALG12
- ALG13
- ALG14
- ALG2
- ALG3
- ALG6
- ALG8
- ALG9
- CXorf45
- DIBD1
- DPAGT1
- DPAGT2
- GLT28D1
- GT8
- HMAT1
- HMT1
- KCR1
- MPDU1
- NOT
- NOT56L
- RFT1
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Homo sapiens (human)
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Choline catabolism
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- ALDH7A1
- ATQ1
- BHMT
- CD92
- CDW92
- CHDH
- CTL1
- DMGDH
- DMGDHL1
- SARDH
- SLC44A1
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Homo sapiens (human)
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Proline catabolism
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- ALDH4
- ALDH4A1
- HSPOX1
- HYPDH
- P5CDH
- PIG6
- POX2
- PRODH
- PRODH2
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Homo sapiens (human)
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Metabolism of serotonin
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Homo sapiens (human)
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Smooth Muscle Contraction
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- ALDH2
- ALDM
- ANX1
- ANX2
- ANX2L4
- ANX6
- ANXA1
- ANXA2
- ANXA6
- C15orf13
- CACNA1G
- CACNA1H
- CACNA1I
- CAD
- CAL1H
- CALD1
- CALM
- CALM1
- CAM
- CAM1
- CAV3
- CDM
- DYSF
- FER1L1
- GUC1A2
- GUC1A3
- GUC1B3
- GUCSA2
- GUCSA3
- GUCSB3
- GUCY1A1
- GUCY1A2
- GUCY1A3
- GUCY1B1
- GUCY1B2
- GUCY1B3
- HSRLC
- ITGA1
- ITGB5
- KIAA0866
- KIAA0894
- KIAA1027
- KIAA1120
- KIAA1123
- KIAA1296
- LMOD1
- LPC1
- LPC2D
- MG53
- MLC1SA
- MLC2
- MLCB
- MLCK
- MLCK1
- MRLC1
- MRLC2
- MRLC3
- MYH11
- MYL10
- MYL11
- MYL12A
- MYL12B
- MYL2A
- MYL5
- MYL6
- MYL6B
- MYL7
- MYL9
- MYLC2A
- MYLC2B
- MYLC2PL
- MYLK
- MYLK1
- MYLPF
- MYRL2
- PAK1
- PAK2
- PDE5
- PDE5A
- PLRLC
- PXN
- RLC
- SCAM1
- SH3D5
- SORBS1
- SORBS3
- TLN
- TLN1
- TMSA
- TMSB
- TPM1
- TPM2
- TPM3
- TPM4
- TRIM72
- VCL
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Homo sapiens (human)
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Metabolism of folate and pterines
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- ALDH1L1
- ALDH1L2
- DHFR
- DHFR2
- DHFRL1
- DHFRP4
- FLOT1
- FOLR2
- FTHFD
- FTHFSDC1
- G21
- HCP1
- MFT
- MFTC
- MTHFC
- MTHFD
- MTHFD1
- MTHFD1L
- MTHFD2
- MTHFD2L
- MTHFR
- MTHFS
- NMDMC
- PCFT
- RFC1
- SHMT1
- SHMT2
- SLC19A1
- SLC25A32
- SLC46A1
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Homo sapiens (human)
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RND2 GTPase cycle
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- ALDH10
- ALDH3A2
- ANKRD26
- ARHGAP1
- ARHGAP35
- ARHGAP5
- ARHN
- ARMS
- BACURD1
- BACURD2
- BLTP3B
- BP230
- BP240
- BPAG1
- C6orf143
- CAV
- CAV1
- CDC42GAP
- CDHF4
- CG1
- CKAP4
- CRIB1
- DEPDC1B
- DLG5
- DMH
- DRCC1
- DSG1
- DST
- DT
- ECK
- EDP1
- EPHA2
- FALDH
- FAM83B
- FBP17
- FNBP1
- FRS2
- FRS3
- GOLGA3
- GRB1
- GRF1
- GRLF1
- HNRPG
- IRAS
- KCTD13
- KIAA0004
- KIAA0042
- KIAA0147
- KIAA0554
- KIAA0583
- KIAA0620
- KIAA0701
- KIAA0728
- KIAA0975
- KIAA1074
- KIAA1215
- KIAA1250
- KIAA1722
- KIDINS220
- KIF14
- KTN1
- LANO
- LAP4
- LEMD3
- LRRC1
- MAN1
- MUC13
- NISCH
- NUDC
- P190A
- PDIP1
- PDLG
- PIK3R1
- PIK3R2
- PKP4
- PLXND1
- PNP1
- POLDIP1
- PRAG1
- PTP1E
- PTPL1
- PTPN13
- RBMX
- RBMXP1
- RECC
- RHO7
- RHOGAP1
- RHOGAP5
- RND2
- SCRB1
- SCRIB
- SGK223
- SHIP164
- SOC
- STB1
- STB2
- TFRC
- TNFAIP1
- TRP32
- TXL
- TXNL
- TXNL1
- UBXD5
- UBXN11
- UHRF1BP1L
- VANGL1
- VANGL2
- VARTUL
- WDR6
- XTP8
- p190ARHOGAP
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Homo sapiens (human)
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RND1 GTPase cycle
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- ALDH10
- ALDH3A2
- ANKRD26
- APE
- ARHGAP35
- ARHGAP5
- ARMS
- BP230
- BP240
- BPAG1
- C1orf8
- C6orf143
- CAV
- CAV1
- CCDC88A
- CPD
- DEPDC1B
- DLG5
- DMH
- DRCC1
- DSP
- DST
- DT
- ECK
- EPHA2
- EPSTI1
- ESA1
- FALDH
- FAM135A
- FAM83B
- FLOT2
- FRS2
- FRS3
- GRB1
- GRB7
- GRDN
- GRF1
- GRLF1
- HNRPG
- KIAA0042
- KIAA0583
- KIAA0720
- KIAA0728
- KIAA1074
- KIAA1212
- KIAA1215
- KIAA1250
- KIAA1411
- KIAA1722
- KIDINS220
- KIF14
- LEMD3
- M17S1
- MAN1
- MUC13
- NGAP
- NOV
- P190A
- PDLG
- PIK3R1
- PIK3R2
- PKP4
- PLEKHG5
- PLXN1
- PLXNA1
- PNP1
- PTP1E
- PTPL1
- PTPN13
- RASAL2
- RBMX
- RBMXP1
- RECC
- RHO6
- RHOGAP5
- RND1
- RRAS2
- SCG10
- SCGN10
- SOC
- STB1
- STB2
- STIP1
- STMN2
- TC21
- TFRC
- TMEM59
- TRP32
- TXL
- TXNL
- TXNL1
- UBXD5
- UBXN11
- VANGL1
- VANGL2
- WDR6
- XTP8
- p190ARHOGAP
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Homo sapiens (human)
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