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alcohol dependence
Summary
- Synonym
-
- alcoholism
- Definition
- A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.
- Super Class
- substance dependence
External Links
- Disease Ontology
- DOID:0050741
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3952 | LEP | leptin | |
| 4684 | NCAM1 | neural cell adhesion molecule 1 | |
| 4915 | NTRK2 | neurotrophic receptor tyrosine kinase 2 | |
| 4985 | OPRD1 | opioid receptor delta 1 | |
| 4986 | OPRK1 | opioid receptor kappa 1 | |
| 4988 | OPRM1 | opioid receptor mu 1 | |
| 5142 | PDE4B | phosphodiesterase 4B | |
| 5443 | POMC | proopiomelanocortin | |
| 6529 | SLC6A1 | solute carrier family 6 member 1 | |
| 6530 | SLC6A2 | solute carrier family 6 member 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 25453 | Gdnf | glial cell derived neurotrophic factor | |
| 25608 | Lep | leptin | |
| 25635 | Mc4r | melanocortin 4 receptor | |
| 29595 | Htr2a | 5-hydroxytryptamine receptor 2A | |
| 81646 | Creb1 | cAMP responsive element binding protein 1 | |
| 81657 | Gabbr1 | gamma-aminobutyric acid type B receptor subunit 1 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O00222 | Metabotropic glutamate receptor 8 | |
| O00327 | Basic helix-loop-helix ARNT-like protein 1 | |
| O15055 | Period circadian protein homolog 2 | |
| P00325 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B | |
| P00326 | Alcohol dehydrogenase 1C | |
| P01189 | Pro-opiomelanocortin | |
| P04150 | Glucocorticoid receptor | |
| P05091 | Aldehyde dehydrogenase, mitochondrial | |
| P06307 | Cholecystokinin | |
| P07108 | Acyl-CoA-binding protein |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9JIM1 | Equilibrative nucleoside transporter 1 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P09208 | Insulin-like receptor |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
