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Standards Ontologies Notations
colorectal cancer

Summary
Definition
A large intestine cancer that is located_in the colon and/or located_in the rectum.
Super Class
large intestine cancer
Disease Ontology
DOID:9256
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 174 in total
Gene ID Gene Symbol Description Source
463 ZFHX3 zinc finger homeobox 3
472 ATM ATM serine/threonine kinase
563 AZGP1 alpha-2-glycoprotein 1, zinc-binding
575 ADGRB1 adhesion G protein-coupled receptor B1
581 BAX BCL2 associated X, apoptosis regulator
639 PRDM1 PR/SET domain 1
672 BRCA1 BRCA1 DNA repair associated
675 BRCA2 BRCA2 DNA repair associated
695 BTK Bruton tyrosine kinase
701 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
Displaying entries 41 - 50 of 125 in total
Gene ID Gene Symbol Description Source
16728 L1cam L1 cell adhesion molecule
16878 Lif leukemia inhibitory factor
16948 Lox lysyl oxidase
17096 Lyn LYN proto-oncogene, Src family tyrosine kinase
17345 Mki67 antigen identified by monoclonal antibody Ki 67
17350 Mlh1 mutL homolog 1
17390 Mmp2 matrix metallopeptidase 2
17395 Mmp9 matrix metallopeptidase 9
18024 Nfe2l2 nuclear factor, erythroid derived 2, like 2
18128 Notch1 notch 1
Displaying entries 1 - 10 of 44 in total
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24346 Ces1c carboxylesterase 1C
24409 Grin2a glutamate ionotropic receptor NMDA type subunit 2A
24648 Serpina1 serpin family A member 1
24842 Tp53 tumor protein p53
24856 Ttr transthyretin
25058 Hk1 hexokinase 1
25149 Esr2 estrogen receptor 2
25233 Akt2 AKT serine/threonine kinase 2
25273 Smo smoothened, frizzled class receptor
Displaying entries 11 - 18 of 18 in total
Gene ID Gene Symbol Description Source
39564 btl breathless
40191 kug kugelei
41166 Calr Calreticulin
41840 Hsc70-4 Heat shock protein 70 cognate 4
42160 htl heartless
43191 Hex-t2 Hexokinase testis 2
43565 Axn Axin
246627 Pgant9 Polypeptide N-Acetylgalactosaminyltransferase 9
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30225 smo smoothened, frizzled class receptor
30682 vegfaa vascular endothelial growth factor Aa
30718 notch1a notch receptor 1a
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
559736 galnt12 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
100006041 rhoab ras homolog gene family, member Ab
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source Organism
373801 tgfb2.L transforming growth factor beta 2 L homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397787 ttr.L transthyretin L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
399187 adam10.S ADAM metallopeptidase domain 10 S homeolog Xenopus laevis (African clawed frog)
399347 fgfr3.S fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog Xenopus laevis (African clawed frog)
432172 akt2.S v-akt murine thymoma viral oncogene homolog 2 S homeolog Xenopus laevis (African clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
172233 unc-40 Netrin receptor unc-40
172689 sup-17 Disintegrin and metalloproteinase domain-containing protein 10 homolog
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175201 stim-1 Stromal interaction molecule 1
175590 cdh-4 Cadherin-4
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
176575 plr-1 putative E3 ubiquitin-protein ligase plr-1
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source
850438 ERS1 cystinosin-like protein ERS1
850614 HXK1 hexokinase 1
851543 OSH2 oxysterol-binding protein related protein OSH2
851670 GIS1 histone demethylase GIS1
852410 CYC8 transcription regulator CYC8
852546 GPX2 glutathione peroxidase GPX2
853313 PBS2 mitogen-activated protein kinase kinase PBS2
853361 ALY2 Aly2p
853770 BUD2 GTPase-activating protein BUD2
853842 GPX1 glutathione peroxidase GPX1
The Human Phenotype Ontology
Displaying all 7 entries
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0006716 Hereditary nonpolyposis colorectal carcinoma
HP:0002891 Uterine leiomyosarcoma
HP:0006753 Neoplasm of the stomach
HP:0001442 Typified by somatic mosaicism
HP:0006740 Transitional cell carcinoma of the bladder
HP:0005584 Renal cell carcinoma
Displaying all 3 entries
Gene ID Gene Symbol Description
4893 NRAS NRAS proto-oncogene, GTPase
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5320 PLA2G2A phospholipase A2 group IIA
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024