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Standards Ontologies Notations
colorectal cancer

Summary
Definition
A large intestine cancer that is located_in the colon and/or located_in the rectum.
Super Class
large intestine cancer
Disease Ontology
DOID:9256
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 101 - 110 of 174 in total
Gene ID Gene Symbol Description Source
5879 RAC1 Rac family small GTPase 1
6416 MAP2K4 mitogen-activated protein kinase kinase 4
6469 SHH sonic hedgehog signaling molecule
6599 SMARCC1 SWI/SNF related BAF chromatin remodeling complex subunit C1
6608 SMO smoothened, frizzled class receptor
6615 SNAI1 snail family transcriptional repressor 1
6714 SRC SRC proto-oncogene, non-receptor tyrosine kinase
6774 STAT3 signal transducer and activator of transcription 3
6786 STIM1 stromal interaction molecule 1
6926 TBX3 T-box transcription factor 3
Displaying entries 61 - 70 of 125 in total
Gene ID Gene Symbol Description Source
20317 Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1
20371 Foxp3 forkhead box P3
20423 Shh sonic hedgehog
20539 Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
20588 Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
20613 Snai1 snail family zinc finger 1
20700 Serpina1a serine (or cysteine) peptidase inhibitor, clade A, member 1A
20701 Serpina1b serine (or cysteine) preptidase inhibitor, clade A, member 1B
20702 Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C
20703 Serpina1d serine (or cysteine) peptidase inhibitor, clade A, member 1D
Displaying entries 1 - 10 of 44 in total
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24346 Ces1c carboxylesterase 1C
24409 Grin2a glutamate ionotropic receptor NMDA type subunit 2A
24648 Serpina1 serpin family A member 1
24842 Tp53 tumor protein p53
24856 Ttr transthyretin
25058 Hk1 hexokinase 1
25149 Esr2 estrogen receptor 2
25233 Akt2 AKT serine/threonine kinase 2
25273 Smo smoothened, frizzled class receptor
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
31293 N Notch
31792 Nrg Neuroglian
32556 Stim Stromal interaction molecule
33196 smo smoothened
33496 lilli lilliputian
34091 Spn28Dc Serpin 28Dc
35560 Bap170 Brahma associated protein 170kD
37455 Egfr Epidermal growth factor receptor
39392 Est-6 Esterase 6
39393 Est-P Esterase P
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30225 smo smoothened, frizzled class receptor
30682 vegfaa vascular endothelial growth factor Aa
30718 notch1a notch receptor 1a
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
559736 galnt12 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
100006041 rhoab ras homolog gene family, member Ab
Displaying entries 11 - 16 of 16 in total
Gene ID Gene Symbol Description Source Organism
100038176 cxcr4 C-X-C motif chemokine receptor 4 Xenopus tropicalis (tropical clawed frog)
100127346 grin2a.L glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog Xenopus laevis (African clawed frog)
100192360 cxcr4.L C-X-C motif chemokine receptor 4 L homeolog Xenopus laevis (African clawed frog)
100485011 galnt12 polypeptide N-acetylgalactosaminyltransferase 12 Xenopus tropicalis (tropical clawed frog)
100491274 rnf43 ring finger protein 43 Xenopus tropicalis (tropical clawed frog)
108719043 galnt12.L polypeptide N-acetylgalactosaminyltransferase 12 L homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
172233 unc-40 Netrin receptor unc-40
172689 sup-17 Disintegrin and metalloproteinase domain-containing protein 10 homolog
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175201 stim-1 Stromal interaction molecule 1
175590 cdh-4 Cadherin-4
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
176575 plr-1 putative E3 ubiquitin-protein ligase plr-1
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source
850438 ERS1 cystinosin-like protein ERS1
850614 HXK1 hexokinase 1
851543 OSH2 oxysterol-binding protein related protein OSH2
851670 GIS1 histone demethylase GIS1
852410 CYC8 transcription regulator CYC8
852546 GPX2 glutathione peroxidase GPX2
853313 PBS2 mitogen-activated protein kinase kinase PBS2
853361 ALY2 Aly2p
853770 BUD2 GTPase-activating protein BUD2
853842 GPX1 glutathione peroxidase GPX1
The Human Phenotype Ontology
Displaying all 7 entries
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0006716 Hereditary nonpolyposis colorectal carcinoma
HP:0002891 Uterine leiomyosarcoma
HP:0006753 Neoplasm of the stomach
HP:0001442 Typified by somatic mosaicism
HP:0006740 Transitional cell carcinoma of the bladder
HP:0005584 Renal cell carcinoma
Displaying all 3 entries
Gene ID Gene Symbol Description
4893 NRAS NRAS proto-oncogene, GTPase
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5320 PLA2G2A phospholipase A2 group IIA
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024