diabetes mellitus

Summary
Synonym
  • diabetes
Definition
A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
Super Class
glucose metabolism disease
Disease Ontology
DOID:9351
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 84 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
338 APOB apolipoprotein B
344 APOC2 apolipoprotein C2
345 APOC3 apolipoprotein C3
348 APOE apolipoprotein E
350 APOH apolipoprotein H
358 AQP1 aquaporin 1 (Colton blood group)
361 AQP4 aquaporin 4
406 BMAL1 basic helix-loop-helix ARNT like 1
653 BMP5 bone morphogenetic protein 5
Displaying entries 21 - 30 of 72 in total
Gene ID Gene Symbol Description Source
14268 Fn1 fibronectin 1
14380 G6pd2 glucose-6-phosphate dehydrogenase 2
14381 G6pdx glucose-6-phosphate dehydrogenase X-linked
14415 Gad1 glutamate decarboxylase 1
14473 Gc vitamin D binding protein
14598 Ggt1 gamma-glutamyltransferase 1
14782 Gsr glutathione reductase
15216 Hfe homeostatic iron regulator
15234 Hgf hepatocyte growth factor
15357 Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Displaying entries 1 - 10 of 46 in total
Gene ID Gene Symbol Description Source
24255 Cftr CF transmembrane conductance regulator
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24385 Gck glucokinase
24446 Hgf hepatocyte growth factor
24464 Hp haptoglobin
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24617 Serpine1 serpin family E member 1
Displaying entries 11 - 20 of 21 in total
Gene ID Gene Symbol Description Source
38372 promL prominin-like
39836 st scarlet
42313 Delta delta
42549 InR Insulin-like receptor
42679 wfs1 wolfram syndrome 1
42803 Hmgcr HMG Coenzyme A reductase
43191 Hex-t2 Hexokinase testis 2
43222 Tl Toll
47905 l(2)03659 lethal (2) 03659
117364 Hex-t1 Hexokinase testis 1
Displaying all 6 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
64274 csf1ra colony stimulating factor 1 receptor, a
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
322857 prom1a prominin 1a
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
559080 cftr CF transmembrane conductance regulator
Displaying all 8 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178748 zmp-3 Matrix metalloproteinase-C
179053 cpr-4 Cathepsin B-like cysteine proteinase 4
179197 cri-2 Putative metalloproteinase inhibitor tag-225
Displaying entries 11 - 14 of 14 in total
Gene ID Gene Symbol Description Source
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
855480 ZWF1 glucose-6-phosphate dehydrogenase
856014 GLR1 glutathione-disulfide reductase GLR1
856533 ECM14 putative metallocarboxypeptidase

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