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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 325 in total
Gene ID Gene Symbol Description Source
197 AHSG alpha 2-HS glycoprotein
207 AKT1 AKT serine/threonine kinase 1
208 AKT2 AKT serine/threonine kinase 2
217 ALDH2 aldehyde dehydrogenase 2 family member
229 ALDOB aldolase, fructose-bisphosphate B
231 AKR1B1 aldo-keto reductase family 1 member B
239 ALOX12 arachidonate 12-lipoxygenase, 12S type
285 ANGPT2 angiopoietin 2
335 APOA1 apolipoprotein A1
336 APOA2 apolipoprotein A2
Displaying entries 1 - 10 of 249 in total
Gene ID Gene Symbol Description Source
11303 Abca1 ATP-binding cassette, sub-family A member 1
11421 Ace angiotensin I converting enzyme
11450 Adipoq adiponectin, C1Q and collagen domain containing
11491 Adam17 a disintegrin and metallopeptidase domain 17
11551 Adra2a adrenergic receptor, alpha 2a
11556 Adrb3 adrenergic receptor, beta 3
11596 Ager advanced glycosylation end product-specific receptor
11601 Angpt2 angiopoietin 2
11609 Agtr2 angiotensin II receptor, type 2
11625 Ahsg alpha-2-HS-glycoprotein
Displaying entries 81 - 90 of 166 in total
Gene ID Gene Symbol Description Source
25634 G6pc1 glucose-6-phosphatase catalytic subunit 1
25645 Adrb3 adrenoceptor beta 3
25651 Selp selectin P
25658 Gckr glucokinase regulator
25664 Pparg peroxisome proliferator-activated receptor gamma
25668 Cd38 CD38 molecule
25669 Cpe carboxypeptidase E
25675 Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase
25692 Plat plasminogen activator, tissue type
25703 Rbp4 retinol binding protein 4
Displaying entries 51 - 60 of 80 in total
Gene ID Gene Symbol Description Source
42679 wfs1 wolfram syndrome 1
42803 Hmgcr HMG Coenzyme A reductase
42850 Atg6 Autophagy-related 6
43183 Ald1 Aldolase 1
43191 Hex-t2 Hexokinase testis 2
43215 amon amontillado
43222 Tl Toll
43223 Lerp lysosomal enzyme receptor protein
43558 Tace tace
43708 Ugt35D1 UDP-glycosyltransferase family 35 member D1
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
30173 nog3 noggin 3
30174 nog1 noggin 1
30262 ins preproinsulin
30667 mtnr1aa melatonin receptor 1A a
30668 mtnr1bb melatonin receptor 1Bb
30682 vegfaa vascular endothelial growth factor Aa
266751 adra2b adrenoceptor alpha 2B
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source Organism
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380341 pon2.L paraoxonase 2 L homeolog Xenopus laevis (African clawed frog)
394283 sdc2.S syndecan 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 69 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
171782 abt-2 ABC transporter domain-containing protein
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
172509 gpdh-3 putative glycerol-3-phosphate dehydrogenase, mitochondrial
173297 F49B2.6 Aminopeptidase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175076 ace-3 Carboxylic ester hydrolase
175182 ver-1 Protein ver-1
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
850678 YBT1 bile acid-transporting ATPase YBT1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
6514 SLC2A2 solute carrier family 2 member 2
2645 GCK glucokinase
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
3990 LIPC lipase C, hepatic type
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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024