GlyCosmos Portal

Mus musculus (house mouse)

Summary

Taxonomy ID: 10090
PubChem Taxonomy: 10090

Genes (662) Glycans (1270) Glycoproteins (13000) Lectins (276) Pathways (1335)

Displaying entries **876 - 900** of **1335** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	GlyTouCan ID
Downregulation of ERBB2:ERBB3 signaling	E3 ubiquitin-protein ligase NRDP1 Polyubiquitin-B Polyubiquitin-C Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A140LHZ9 P0CG49 P0CG50 P31750 P56974 P62983 P62984 P70424 Q60823 Q61526 Q80U87 Q8BH75 Q9WUA6	Akt Akt1 Akt2 Akt3 Erbb2 Erbb3 Flrf Kiaa0055 Kiaa3023 Neu Nrdp1 Nrg1 Nrg2 Rac Rnf41 Rps27a Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2 Ubpy Usp8
Negative regulation of the PI3K/AKT network	Acyl-coenzyme A thioesterase THEM4 PH domain leucine-rich repeat-containing protein phosphatase 1 PH domain leucine-rich repeat-containing protein phosphatase 2 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Tribbles homolog 3	O08586 P31750 Q3UUI3 Q60823 Q8BXA7 Q8CHE4 Q8K4K2 Q9WUA6	Akt Akt1 Akt2 Akt3 Ctmp Kiaa0606 Mmac1 Nipk Phlpp Phlpp1 Phlpp2 Phlppl Plekhe1 Pten Rac Scop Them4 Trb3 Trib3
FLT3 Signaling	Cyclin-dependent kinase inhibitor 1B Fms-related tyrosine kinase 3 ligand Forkhead box protein O3 GRB2-associated-binding protein 2 GRB2-related adaptor protein 2 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 10 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Receptor-type tyrosine-protein kinase FLT3 Son of sevenless homolog 1	O89100 P08556 P26450 P31750 P32883 P42337 P46414 P49772 Q00342 Q60760 Q60823 Q61411 Q62245 Q9WUA6 Q9WVH4 Q9Z1S8	Akt Akt1 Akt2 Akt3 Cdkn1b Fkhr2 Flk-2 Flt-3 Flt3 Flt3l Flt3lg Foxo3 Foxo3a Gab2 Gads Grap2 Grb10 Grb2l Grid Hras Hras1 Kras Kras2 Meg1 Mona Nras Pik3ca Pik3r1 Rac Sos1
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Cyclic AMP-responsive element-binding protein 1 Cyclin-dependent kinase inhibitor 1B Exportin-1 Forkhead box protein O3 Mitogen-activated protein kinase 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Serine/threonine-protein kinase Kist	P31750 P46414 P63085 P97343 Q01147 Q60823 Q6P5F9 Q9WUA6 Q9WVH4	Akt Akt1 Akt2 Akt3 Cdkn1b Creb-1 Creb1 Crm1 Erk2 Fkhr2 Foxo3 Foxo3a Kis Kist Mapk Mapk1 Prkm1 Rac Uhmk1 Xpo1
VEGFR2 mediated vascular permeability	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Cadherin-5 Calmodulin-1 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Caveolin-1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Heat shock protein HSP 90-alpha Junction plakoglobin Nitric oxide synthase 3 Proline-rich protein 5 Proto-oncogene vav RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase mTOR Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3	O88643 P07901 P0DP26 P26231 P27870 P30999 P31750 P49817 P55284 P63001 P70313 Q02248 Q02257 Q3UUI3 Q60823 Q60992 Q61036 Q6QI06 Q812A5 Q8BKH7 Q8CIN4 Q8K4K2 Q9DCJ1 Q9JLN9 Q9R0C8 Q9WUA6 Q9Z2A0	Akt Akt1 Akt2 Akt3 Calm Calm1 Cam Cam1 Catna1 Catnb Catns Cav Cav1 Cdh5 Ctmp Ctnna1 Ctnnb1 Ctnnd1 Ecnos Frap Frap1 Gbl Hsp86 Hsp86-1 Hsp90aa1 Hspca Jup Kiaa0384 Kiaa1999 Lst8 Mapkap1 Mip1 Mlst8 Mtor Nipk Nos3 Pak-3 Pak1 Pak2 Pak3 Paka Pakb Pdk1 Pdpk1 Protor1 Prr5 Rac Rac1 Rictor Sin1 Stk4 Them4 Trb3 Trib3 Vav Vav1 Vav2 Vav3
Cyclin E associated events during G1/S transition	CDK-activating kinase assembly factor MAT1 CDK5 and ABL1 enzyme substrate 1 Cyclin-H Cyclin-dependent kinase 2 Cyclin-dependent kinase 7 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 M-phase inducer phosphatase 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Retinoblastoma-associated protein Wee1-like protein kinase	P13405 P31750 P39689 P46414 P47810 P48964 P51949 P97377 Q03147 Q60823 Q61457 Q61458 Q9ESJ1 Q9WUA6 Q9Z238	Akt Akt1 Akt2 Akt3 Cables Cables1 Cak Ccne Ccne1 Ccne2 Ccnh Cdc25a Cdc25m3 Cdk2 Cdk7 Cdkn1a Cdkn1b Cdkn2 Cdkn7 Cip1 Crk4 Mat1 Mnat1 Mo15 Mpk-7 Rac Rb-1 Rb1 Waf1 Wee1
Cyclin A:Cdk2-associated events at S phase entry	CDK-activating kinase assembly factor MAT1 CDK5 and ABL1 enzyme substrate 1 Cyclin-A1 Cyclin-A2 Cyclin-H Cyclin-dependent kinase 2 Cyclin-dependent kinase 7 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Fizzy-related protein homolog M-phase inducer phosphatase 1 M-phase inducer phosphatase 2 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Retinoblastoma-associated protein Wee1-like protein kinase	P13405 P30306 P31750 P39689 P46414 P47810 P48964 P51943 P51949 P97377 Q03147 Q60823 Q61456 Q61458 Q9ESJ1 Q9R1K5 Q9WUA6	Akt Akt1 Akt2 Akt3 Cables Cables1 Cak Ccna Ccna1 Ccna2 Ccnh Cdc25a Cdc25b Cdc25m2 Cdc25m3 Cdk2 Cdk7 Cdkn1a Cdkn1b Cdkn2 Cdkn7 Cip1 Crk4 Cyca Cyca2 Fyr Fzr Fzr1 Mat1 Mnat1 Mo15 Mpk-7 Rac Rb-1 Rb1 Waf1 Wee1
TP53 Regulates Metabolic Genes	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Cytochrome c oxidase assembly protein COX11, mitochondrial Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX18, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6B1 Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A-related protein, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit NDUFA4 Cytochrome c, somatic DNA damage-inducible transcript 4 protein Fructose-2,6-bisphosphatase TIGAR GTP-binding protein Rheb Glucose-6-phosphate 1-dehydrogenase X Glucose-6-phosphate isomerase Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Glutathione peroxidase 2 Glutathione reductase, mitochondrial Hamartin Leucine-rich PPR motif-containing protein, mitochondrial Neutral amino acid transporter 9 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-5, mitochondrial Protein SCO1 homolog, mitochondrial Protein SCO2 homolog, mitochondrial RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Serine/threonine-protein kinase mTOR Sestrin-1 Sestrin-2 Sestrin-3 Surfeit locus protein 1 Target of rapamycin complex subunit LST8 Thioredoxin reductase 1, cytoplasmic Thioredoxin Translational activator of cytochrome c oxidase 1 Tuberin	D3Z7P3 O54950 O70456 O88653 P00397 P00405 P00416 P06745 P09925 P10639 P12787 P17665 P19536 P19783 P31750 P35700 P43024 P47791 P56391 P56393 P58006 P58043 P61982 P62259 P62897 P63101 P68254 P68510 P99029 Q00612 Q571F8 Q5EG47 Q5SUC9 Q60823 Q61037 Q61171 Q61387 Q62425 Q64445 Q6NTA4 Q6P8I6 Q6PAM0 Q6PB66 Q7TT45 Q80X95 Q8BGD6 Q8BGM7 Q8BH51 Q8BRK8 Q8BZA9 Q8CF66 Q8K0C8 Q8K0Z7 Q8K4Q0 Q8VC74 Q8VCL2 Q91WG5 Q921J2 Q99K70 Q9CPQ1 Q9CQ22 Q9CQV8 Q9CR63 Q9CYP7 Q9D1L9 Q9D3F7 Q9D7J4 Q9DCJ1 Q9EP53 Q9JHC0 Q9JHS3 Q9JLN9 Q9JMH6 Q9R078 Q9WUA6	Akt Akt1 Akt2 Akt3 COI COII COIII COX2 Ccdc44 Cox11 Cox14 Cox16 Cox18 Cox19 Cox20 Cox4 Cox4a Cox4i1 Cox5a Cox5b Cox6a1 Cox6al Cox6b Cox6b1 Cox6c Cox7a2l Cox7b Cox7c Cox7c1 Cox7rp Cox8 Cox8a Cox8l Coxiv Cycs Ddit4 Dig2 Fam36a Frap Frap1 G6pd G6pd-1 G6pdx Gbl Gls Gls1 Gls2 Gpi Gpi1 Gpx2 Gr1 Gsr Hbxip Kiaa0243 Kiaa0838 Kiaa4146 Lamtor1 Lamtor2 Lamtor3 Lamtor4 Lamtor5 Lrp130 Lrpprc Lst8 Map2k1ip1 Mapbp Mapbpip Mapksp1 Mkrn3 Mlst8 Msp23 Mtco1 Mtco2 Mtco3 Mtor Ndufa4 Oxa1l2 Pa26 Paga Prdx1 Prdx2 Prdx5 Prdx6 Prkaa1 Prkaa2 Prkaac Prkab1 Prkab2 Prkag1 Prkag2 Prkag3 Rac Ragd Raptor Redd1 Rheb Robld3 Rptor Rraga Rragb Rragc Rragd Rtp801 Scaf1 Sco1 Sco2 Sesn1 Sesn2 Sesn3 Sest1 Sfn Silg81 Slc38a9 Surf-1 Surf1 Taco1 Tdpx1 Tdpx2 Tigar Tpx Trxr1 Tsc1 Tsc2 Txn Txn1 Txnrd1 Xip Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz mt-Co1 mt-Co2 mt-Co3
Regulation of TP53 Activity through Acetylation	Bromodomain and PHD finger-containing protein 3 Bromodomain-containing protein 1 Bromodomain-containing protein 7 Cellular tumor antigen p53 Chromatin modification-related protein MEAF6 Chromodomain-helicase-DNA-binding protein 4 DNA helicase Histone acetyltransferase KAT6A Histone acetyltransferase p300 Histone deacetylase 1 Histone deacetylase 2 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Inhibitor of growth protein 5 Metastasis-associated protein MTA2 Methyl-CpG-binding domain protein 3 Peregrin Protein PML RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Transcriptional repressor p66 alpha Transcriptional repressor p66-beta	B1AR17 B2KF05 B2RRD7 B2RWS6 G5E8P1 O09106 O88665 P02340 P31750 P70288 Q2VPQ9 Q60823 Q60953 Q60972 Q60973 Q6PDQ2 Q8BZ21 Q8CHY6 Q8VHR5 Q9D8Y8 Q9R190 Q9WUA6 Q9Z2D8	Akt Akt1 Akt2 Akt3 Bp75 Brd1 Brd7 Brpf1 Brpf2 Brpf3 Chd3 Chd4 Ep300 Gatad2a Gatad2b Hdac1 Hdac2 Ing5 Kat6a Kiaa4191 Mbd3 Meaf6 Moz Mta1l1 Mta2 Myst3 P300 P53 Pml Rac Rbap46 Rbap48 Rbbp4 Rbbp7 Tp53 Trp53 Yy1bp
CD28 dependent PI3K/Akt signaling	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Mitogen-activated protein kinase kinase kinase 14 Mitogen-activated protein kinase kinase kinase 8 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proline-rich protein 5 Proto-oncogene tyrosine-protein kinase LCK RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Serine/threonine-protein kinase mTOR T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3 Tyrosine-protein kinase Fyn	O08908 P06240 P26450 P31041 P31750 P39688 P42082 P42337 Q00609 Q07174 Q3UUI3 Q60823 Q64143 Q6QI06 Q812A5 Q8BKH7 Q8K4K2 Q9DCJ1 Q9JLN9 Q9WUA6 Q9WUL6 Q9Z2A0	Akt Akt1 Akt2 Akt3 B7 Cd28 Cd80 Cd86 Cot Ctmp Frap Frap1 Fyn Gbl Kiaa1999 Lck Lsk-t Lst8 Map3k14 Map3k8 Mapkap1 Mip1 Mlst8 Mtor Nik Nipk Pdk1 Pdpk1 Pik3ca Pik3r1 Pik3r2 Pik3r3 Protor1 Prr5 Rac Rictor Sin1 Them4 Tpl2 Trb3 Trib3
CTLA4 inhibitory signaling	Cytotoxic T-lymphocyte protein 4 Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11	P05480 P06240 P09793 P25911 P31750 P35235 P39688 P42082 P62715 P63330 Q00609 Q04736 Q60823 Q60996 Q61151 Q6PD03 Q6PD28 Q76MZ3 Q7TNL5 Q7TNP2 Q9WUA6	Akt Akt1 Akt2 Akt3 B7 Cd152 Cd80 Cd86 Ctla4 Fyn Kiaa4006 Lck Lsk-t Lyn Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Ptpn11 Rac Src Yes Yes1
Regulation of TP53 Degradation	3-phosphoinositide-dependent protein kinase 1 Cellular tumor antigen p53 Cyclin-A1 Cyclin-A2 Cyclin-G1 Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 Death domain-associated protein 6 E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RNF34 E3 ubiquitin-protein ligase rififylin PHD finger protein 20 Polyubiquitin-B Polyubiquitin-C Proline-rich protein 5 Protein Mdm4 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Serine-protein kinase ATM Serine/threonine-protein kinase Chk2 Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase mTOR Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O35613 O35618 O88623 P02340 P0CG49 P0CG50 P11440 P23804 P31750 P51943 P51945 P62715 P62983 P62984 P63330 P97377 Q60823 Q60996 Q61456 Q62388 Q6A4J8 Q6QI06 Q6ZQM0 Q76MZ3 Q7TNP2 Q812A5 Q8BKH7 Q8BLG0 Q99KR6 Q9DCJ1 Q9JLN9 Q9WUA6 Q9WVC6 Q9Z265 Q9Z2A0	Akt Akt1 Akt2 Akt3 Atm Ccna Ccna1 Ccna2 Ccng Ccng1 Cdc2 Cdc2a Cdk1 Cdk2 Cdkn1 Cdkn2 Chek2 Chk2 Cyca Cyca2 Daxx Frap Frap1 Gbl Hausp Hca58 Kiaa1999 Lst8 Mapkap1 Mdm2 Mdm4 Mdmx Mip1 Mlst8 Mtor P53 Pdk1 Pdpk1 Phf20 Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5c Protor1 Prr5 Rac Rad53 Rffl Rictor Rnf34 Rps27a Sgk Sgk1 Sin1 Tp53 Trp53 Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2 Ubp41 Usp2 Usp7
Regulation of TP53 Activity through Association with Co-factors	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 PHD finger protein 20 POU domain, class 4, transcription factor 1 POU domain, class 4, transcription factor 2 Protein BANP RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase RelA-associated inhibitor Tumor protein 63 Tumor protein p73 Zinc finger protein 385A	O88898 P02340 P17208 P31750 Q5I1X5 Q60823 Q62415 Q63934 Q8BLG0 Q8CG79 Q8VBU8 Q8VD12 Q9JJP2 Q9WUA6	Akt Akt1 Akt2 Akt3 Aspp1 Aspp2 Banp Brn-3 Brn-3.2 Brn3 Brn3a Brn3b Hca58 Hzf Nkip1 P53 P63 P73 P73l Phf20 Pou4f1 Pou4f2 Ppp1r13b Ppp1r13l Rac Smar1 Tp53 Tp53bp2 Tp63 Tp73 Tp73l Trp53 Trp53bp2 Trp63 Trp73 Zfp385a Znf385a
G beta:gamma signalling through PI3Kgamma	3-phosphoinositide-dependent protein kinase 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Transforming protein RhoA	P29387 P31750 P50153 P61953 P62874 P62880 P62881 P63078 P63213 P63216 Q3U6Q4 Q5SW28 Q60823 Q61011 Q61012 Q61016 Q61017 Q80SZ7 Q9CXP8 Q9DAS9 Q9JHG7 Q9JMF3 Q9QUI0 Q9WUA6 Q9Z2A0	Akt Akt1 Akt2 Akt3 Arha Arha2 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng1 Gng10 Gng11 Gng12 Gng13 Gng2 Gng3 Gng4 Gng5 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt2 Gngt3 Gngt4 Gngt5 Gngt7 Gngt8 Gngt9 Pdk1 Pdpk1 Pi3kg1 Pik3cg Pik3r5 Pik3r6 Rac Rhoa
RAB GEFs exchange GTP for GDP on RABs	14-3-3 protein epsilon ALS2 C-terminal-like protein Alsin Ankyrin repeat domain-containing protein 27 BLOC-3 complex member HPS1 BLOC-3 complex member HPS4 DENN domain containing 4A DENN domain-containing protein 1A DENN domain-containing protein 1B DENN domain-containing protein 1C DENN domain-containing protein 2A DENN domain-containing protein 2B DENN domain-containing protein 2C DENN domain-containing protein 2D DENN domain-containing protein 3 DENN domain-containing protein 4B DENN domain-containing protein 4C DENN domain-containing protein 5A DENN domain-containing protein 5B GTPase-activating protein and VPS9 domain-containing protein 1 Guanine nucleotide exchange factor for Rab-3A Guanine nucleotide exchange factor subunit RIC1 MAP kinase-activating death domain protein Myotubularin-related protein 13 Myotubularin-related protein 5 Protein DENND6A Protein DENND6B RAB6A-GEF complex partner protein 2 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rab GDP dissociation inhibitor alpha Rab GDP dissociation inhibitor beta Rab proteins geranylgeranyltransferase component A 1 Rab proteins geranylgeranyltransferase component A 2 Rab-3A-interacting protein Rab3 GTPase-activating protein catalytic subunit Rab3 GTPase-activating protein non-catalytic subunit Rab5 GDP/GTP exchange factor Ras and Rab interactor 1 Ras and Rab interactor 2 Ras and Rab interactor 3 Ras and Rab interactor-like protein Ras-related protein Rab-10 Ras-related protein Rab-12 Ras-related protein Rab-13 Ras-related protein Rab-14 Ras-related protein Rab-18 Ras-related protein Rab-1A Ras-related protein Rab-1B Ras-related protein Rab-21 Ras-related protein Rab-27A Ras-related protein Rab-27B Ras-related protein Rab-31 Ras-related protein Rab-32 Ras-related protein Rab-35 Ras-related protein Rab-38 Ras-related protein Rab-39A Ras-related protein Rab-39B Ras-related protein Rab-3A Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-7a Ras-related protein Rab-7b Ras-related protein Rab-8A Ras-related protein Rab-8B Ras-related protein Rab-9A Ras-related protein Rab-9B Serine/threonine-protein kinase ULK1 Trafficking protein particle complex 8 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 11 Trafficking protein particle complex subunit 12 Trafficking protein particle complex subunit 13 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 3 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Vacuolar fusion protein CCZ1 homolog Vacuolar fusion protein MON1 homolog A Vacuolar fusion protein MON1 homolog B	A0A286YCX6 A2RSQ0 A2RT67 A6H8H2 B2RXC1 E9PXF8 E9Q8V6 O08983 O55013 O70405 P31750 P35278 P35279 P35282 P35283 P35293 P50396 P51150 P55258 P59729 P61021 P61027 P61028 P61294 P62259 P62821 P63011 Q3TIR1 Q3TLI0 Q3U0M1 Q3U1T9 Q3U1Y4 Q3UMR0 Q5NCF2 Q60823 Q60I26 Q61598 Q68EF0 Q69ZJ7 Q6P9P8 Q6PAL8 Q6PAR5 Q6PDG8 Q6PHN9 Q6ZPE2 Q78XR0 Q80U28 Q80UJ7 Q80UW3 Q8BH65 Q8BHC1 Q8BHD0 Q8BHH2 Q8BHT7 Q8BMG7 Q8BMQ8 Q8C1Y8 Q8C4S8 Q8CFK6 Q8K2L8 Q8K382 Q8QZZ8 Q8VDV3 Q8VEA8 Q91V41 Q91VV4 Q920R0 Q921E2 Q921Q7 Q924W7 Q99KG7 Q99P58 Q9CQA1 Q9CQD1 Q9CQP2 Q9CZE3 Q9D1G1 Q9D289 Q9D684 Q9D9V7 Q9DD03 Q9ERI2 Q9ES56 Q9JM13 Q9JME7 Q9QXG2 Q9QZD5 Q9R0M6 Q9WUA6	Akt Akt1 Akt2 Akt3 Als2 Als2cl Ankrd27 Bet3 Bsg4 Bsp4 Ccz1 Chm Chml D9Bwg0185e Denn2b Dennd1a Dennd1b Dennd1c Dennd2a Dennd2b Dennd2c Dennd2d Dennd3 Dennd4a Dennd4b Dennd4c Dennd5a Dennd5b Dennd6a Dennd6b Ep Gapex5 Gapvd1 Gdi1 Gdi2 Gdi3 Hps Hps1 Hps4 Kiaa0066 Kiaa0258 Kiaa0358 Kiaa0476 Kiaa0839 Kiaa0870 Kiaa0872 Kiaa1432 Kiaa1521 Kiaa1882 Kiaa3020 Le Madd Mel Mon1a Mon1b Mtmr5 Nibp Rab1 Rab10 Rab12 Rab13 Rab14 Rab18 Rab1A Rab1b Rab21 Rab27a Rab27b Rab31 Rab32 Rab35 Rab38 Rab39 Rab39a Rab39b Rab3a Rab3gap Rab3gap1 Rab3gap2 Rab3il1 Rab3ip Rab5a Rab5b Rab5c Rab6 Rab6a Rab6b Rab6ip1 Rab7 Rab7a Rab7b Rab8 Rab8a Rab8b Rab9 Rab9a Rab9b Rabex5 Rabgdia Rabgef1 Rabin8 Rac Rep1 Rep2 Rgp1 Ric1 Rin1 Rin2 Rin3 Rinl Sbdn Sbf1 Sbf2 Sedl Sid99 St5 Tmem1 Trappc1 Trappc10 Trappc11 Trappc12 Trappc13 Trappc2 Trappc2l Trappc3 Trappc4 Trappc5 Trappc6a Trappc6b Trappc8 Trappc9 Ttc15 Ulk1 Varp Ywhae nnyRab5a
MTOR signalling	14-3-3 protein beta/alpha GTP-binding protein Rheb Neutral amino acid transporter 9 Proline-rich AKT1 substrate 1 RAC-alpha serine/threonine-protein kinase Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8	O88653 P31750 Q6NTA4 Q7TT45 Q80X95 Q8BGD6 Q8CF66 Q8K4Q0 Q921J2 Q99K70 Q9CQ22 Q9CQV8 Q9D1F4 Q9D1L9 Q9DCJ1 Q9JHS3 Q9JLN9	Akt Akt1 Akt1s1 Frap Frap1 Gbl Hbxip Lamtor1 Lamtor2 Lamtor3 Lamtor4 Lamtor5 Lst8 Map2k1ip1 Mapbp Mapbpip Mapksp1 Mlst8 Mtor Pras Rac Ragd Raptor Rheb Robld3 Rptor Rraga Rragb Rragc Rragd Slc38a9 Xip Ywhab
AKT phosphorylates targets in the cytosol	Caspase-9 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase makorin-1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Proline-rich AKT1 substrate 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Tuberin	P23804 P31750 P39689 P46414 Q60680 Q60823 Q61037 Q8C3Q9 Q9D1F4 Q9QXP6 Q9WUA6	Akt Akt1 Akt1s1 Akt2 Akt3 Casp9 Cdkn1a Cdkn1b Chuk Cip1 Ikka Mch6 Mdm2 Mkrn1 Pras Rac Tsc2 Waf1
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Akr1c20 protein Aldo-keto reductase family 1 member C21 Carbonyl reductase [NADPH] 1 Estradiol 17 beta-dehydrogenase 5 Hematopoietic prostaglandin D synthase Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase 3 Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin-H2 D-isomerase Thromboxane-A synthase	O09114 O35074 O88962 P22437 P36423 P48758 P70694 Q05769 Q8BWM0 Q8VC77 Q91WR5 Q9JHF7 Q9JM51 Q9R0Q7	Akr1c20 Akr1c21 Akr1c6 Cbr Cbr1 Cox-1 Cox-2 Cox1 Cox2 Cyp12 Cyp5 Cyp5a1 Cyp8 Cyp8b1 Gbf1 Gsts Hpgds Hsd17b5 Pgds Pges Pges2 Pghs-b Ptgds Ptgds2 Ptges Ptges2 Ptges3 Ptgis Ptgs1 Ptgs2 Sid3177 Tbxas1 Tebp Tis10
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	3 beta-hydroxysteroid dehydrogenase type 7 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Akr1c20 protein Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1 member D1 Bile acid receptor Cytochrome P450 7A1 Cytochrome P450 7B1 Estradiol 17 beta-dehydrogenase 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Prostacyclin synthase Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial	O35074 O88962 P28700 P70365 P70694 Q60641 Q60991 Q61026 Q64505 Q8VC77 Q8VCX1 Q91WR5 Q9DBG1 Q9EQC1	Akr1c20 Akr1c21 Akr1c6 Akr1d1 Bar Cyp12 Cyp27a1 Cyp7 Cyp7a1 Cyp7b1 Cyp8 Cyp8b1 Fxr Grip1 Hsd17b5 Hsd3b7 Ncoa1 Ncoa2 Nr1h4 Nr2b1 Ptgis Rip14 Rxra Src1 Src2 Tif2
Estrogen biosynthesis	17-beta-hydroxysteroid dehydrogenase type 1 Aldo-keto reductase family 1 member B7 Aldo-keto reductase family 1, member B10 (aldose reductase) Aldose reductase-related protein 2 Aromatase Estradiol 17-beta-dehydrogenase 11 Estradiol 17-beta-dehydrogenase 2 Hydroxysteroid (17-beta) dehydrogenase 14	E9Q3D4 G5E895 P21300 P28649 P45377 P51656 P51658 Q9EQ06	Akr1b10 Akr1b7 Akr1b8 Arom Avdp Cyp19 Cyp19a1 Dhrs8 Edh17b1 Edh17b2 Fgfrp Hsd17b1 Hsd17b11 Hsd17b14 Hsd17b2 Pan1b
Fructose biosynthesis	Aldo-keto reductase family 1 member B1 Sorbitol dehydrogenase	P45376 Q64442	Akr1b1 Akr1b3 Aldor1 Aldr1 Alr2 Sdh1 Sord	G58161NS
Pregnenolone biosynthesis	Adrenodoxin, mitochondrial Aldo-keto reductase family 1 member B1 Cholesterol side-chain cleavage enzyme, mitochondrial Ferredoxin-2, mitochondrial NADPH Peripheral-type benzodiazepine receptor-associated protein 1 STARD3 N-terminal-like protein StAR-related lipid transfer protein 3 StAR-related lipid transfer protein 4 StAR-related lipid transfer protein 6 Steroidogenic acute regulatory protein, mitochondrial Translocator protein	P45376 P46656 P50637 P51557 P59096 Q61542 Q61578 Q7TNF8 Q99JV5 Q9CPW2 Q9DCI3 Q9QZ82	Akr1b1 Akr1b3 Aldor1 Aldr1 Alr2 Bzrap1 Bzrp Cyp11a Cyp11a1 Es64 Fdx1 Fdx1l Fdx2 Fdxr Kiaa0612 Mbr Mentho Mln64 Rbp1 Star Stard3 Stard3nl Stard4 Stard6 Tspo Tspoap1
Glutathione conjugation	Aldo-keto reductase family 1 member A1 Glutathione S-transferase 3, mitochondrial Glutathione S-transferase A1 Glutathione S-transferase A2 Glutathione S-transferase A3 Glutathione S-transferase Mu 1 Glutathione S-transferase Mu 2 Glutathione S-transferase Mu 3 Glutathione S-transferase Mu 4 Glutathione S-transferase Mu 5 Glutathione S-transferase Mu 6 Glutathione S-transferase Mu 7 Glutathione S-transferase P 1 Glutathione S-transferase P 2 Glutathione S-transferase kappa 1 Glutathione S-transferase omega-1 Glutathione S-transferase omega-2 Glutathione S-transferase theta-1 Glutathione S-transferase theta-2 Glutathione S-transferase Glutathione S-transferase Hematopoietic prostaglandin D synthase Maleylacetoacetate isomerase Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 S-formylglutathione hydrolase	A2RST1 E9Q6L7 O09131 O35660 P10648 P10649 P13745 P15626 P19157 P19639 P30115 P46425 P48774 Q61133 Q64471 Q6P8Q0 Q80W21 Q8K2Q2 Q8R5I6 Q91VS7 Q9CPU4 Q9DCM2 Q9JHF7 Q9JII6 Q9R0P3 Q9WVL0	Akr1a1 Akr1a4 Es10 Esd Fsc2 Gm10639 Gst2 Gsta Gsta1 Gsta13 Gsta2 Gsta3 Gsta5 Gstk1 Gstm1 Gstm2 Gstm3 Gstm4 Gstm5 Gstm6 Gstm7 Gstm7-7 Gsto1 Gsto2 Gstp1 Gstp2 Gstpia Gstpib Gsts Gstt1 Gstt2 Gstx Gstya Gstyc Gstz1 Gtsttl Hpgds Maai Mgst1 Mgst2 Mgst3 Pgds Ptgds2 Sid478
Formation of xylulose-5-phosphate	Aldo-keto reductase family 1 member A1 L-xylulose reductase Lambda-crystallin homolog Sorbitol dehydrogenase Xylulose kinase	Q3TNA1 Q64442 Q91X52 Q99KP3 Q9JII6	Akr1a1 Akr1a4 Cry Cryl1 Dcxr Sdh1 Sord Xylb
Intra-Golgi traffic	ADP-ribosylation factor 1 Alkaline phosphatase, germ cell type Alkaline phosphatase Alpha-soluble NSF attachment protein BET1-like protein Beta-soluble NSF attachment protein Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 Cytohesin-1 Cytohesin-2 Cytohesin-3 Cytohesin-4 Gamma-soluble NSF attachment protein Golgi SNAP receptor complex member 1 Golgi SNAP receptor complex member 2 Guanine nucleotide exchange factor subunit RIC1 Intestinal-type alkaline phosphatase RAB6A-GEF complex partner protein 2 Ras-related protein Rab-30 Ras-related protein Rab-33B Ras-related protein Rab-36 Ras-related protein Rab-39A Synaptobrevin homolog YKT6 Synaptosomal-associated protein 29 Syntaxin-16 Syntaxin-5 Syntaxin-6 Thyroid hormone receptor interactor 11 Vacuolar protein sorting-associated protein 45 Vesicle transport through interaction with t-SNAREs homolog 1A Vesicle-fusing ATPase	E9Q512 F8VPQ6 O08967 O35153 O35166 O35963 O88630 O89116 P24822 P24823 P28663 P46460 P63034 P84078 P97390 Q3UM29 Q69ZJ7 Q80YW0 Q8BHD0 Q8BHT7 Q8BVI5 Q8C0L8 Q8CAM5 Q8CI04 Q8K1E0 Q8R1U1 Q8R3I3 Q921L5 Q923S9 Q9CQW1 Q9CWZ7 Q9DB05 Q9ERB0 Q9JJA2 Q9JKK1 Q9QX11 Q9Z160	Akp-3 Akp3 Akp5 Alpg Alpi Alppl2 Arf1 Bet1l Cog1 Cog2 Cog3 Cog4 Cog5 Cog6 Cog7 Cog8 Cyth1 Cyth2 Cyth3 Cyth4 Eap Gosr1 Gosr2 Grp1 Gs15 Gs27 Gs28 Iap Kiaa0258 Kiaa1134 Kiaa1432 Ldlb Ldlc Napa Napb Napg Nsf Pscd1 Pscd2 Pscd3 Pscd4 Rab30 Rab33b Rab36 Rab39 Rab39a Rgp1 Ric1 Rsb30 Sec7b Skd2 Snap29 Snapa Snapb Snapg Stx16 Stx5 Stx5a Stx6 Trip11 Vps45 Vps45a Vti1 Vti1a Vti1l2 Ykt6

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