GlyCosmos Portal

Rattus norvegicus (Norway rat)

Summary

Taxonomy ID: 10116
PubChem Taxonomy: 10116

Genes (2388) Glycans (773) Glycoproteins (2551) Lectins (167) Pathways (998)

Displaying entries **551 - 575** of **998** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZXR7 D3ZYL0 M0RA08 Q56DL5 Q63691 Q8R2E7 Q9JHX4 Q9QX05 Q9Z2P5	Casp8 Cd14 Fadd Ly96 Plin3 Rip3 Ripk1 Ripk3 Ticam1 Ticam2 Tlr4
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 7 Polyubiquitin-B Polyubiquitin-C Prostate transmembrane protein, androgen induced 1 Serine-threonine kinase receptor-associated protein TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A8I5Y0P5 A0A8I6A5Y3 A0A8I6AFY1 M0RCH9 O70436 O88406 P0CG51 P17246 P38438 P62982 P80204 P84025 Q5XIG8 Q63429 Q91XN4	Bambi LOC100360645 Madh2 Madh3 Madh7 Mtmr4 Pmepa1 Rps27a Smad2 Smad3 Smad7 Smurf2 Strap Tgfb1 Tgfbr1 Tgfbr2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Unrip
Pyroptosis	Apoptosis regulator BAX BCL2-antagonist/killer 1 Caspase-1 Caspase-3 Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 3 Charged multivesicular body protein 4B Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cytochrome c domain-containing protein Cytochrome c, somatic Elastase, neutrophil expressed Gasdermin D Gasdermin E Granzyme B High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Similar to Cytochrome c, somatic	A0A096MJ11 A0A0G2K6P4 A0A8I5Y7D7 A0A8I5ZP83 A0A8I5ZY10 A0A8I6AB52 A0A8I6AQ75 A0A8I6GBU6 D3ZXV2 D4A488 D4A5L9 D4A7H9 F1MAG0 F7EQF3 P16598 P18291 P43527 P55213 P62898 P63159 P97636 Q569C1 Q63264 Q63690 Q8CGS4	AC128290.1 Bak1 Bax Casp1 Casp3 Chmp2a Chmp2b Chmp3 Chmp4b Chmp4c Chmp6 Chmp7 Cpp32 Cycs Cycsl2 Cycsl3 Elane Gsdmd Gsdme Gzmb Hmg-1 Hmg1 Hmgb1 Hmgb1-ps33 Hmgb1-ps4 Hmgb1l1 Hmgb1l2 Hmgb1l5 Igif Il18 Il1a Il1b Il1bc Il1bce LOC108349189 LOC134483981 LOC690675 RGD1562558 Vps24
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Calmodulin-3 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	D4A3N4 F1LQT1 M0R5U4 P09456 P0DP31 P12368 P12369 P21932 P26769 P26770 P27791 P40146 P68182 P81377 Q03343 Q04400	Adcy1 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 CaMIII Calm3 Cam3 Camc Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b
Defensins	Alpha-defensin N-terminal domain-containing protein Beta-defensin 14 Beta-defensin 17 Beta-defensin 18 Beta-defensin 1 Beta-defensin 25 Beta-defensin 30 Beta-defensin 41 Beta-defensin 43 Beta-defensin 4 Beta-defensin Beta-defensin Beta-defensin Beta-defensin Defensin alpha 10 Defensin alpha 11 Defensin alpha 24 Defensin alpha 4 Defensin alpha 6 Defensin alpha 8 Defensin alpha 9 Defensin alpha-like protein 1 Neutrophil antibiotic peptide NP-2 Neutrophil antibiotic peptide NP-3B	A0A8I6GLV0 A0A8J8YAJ6 F1LSU5 F7EMF7 F7FD31 O88514 O89117 Q32ZF3 Q32ZF5 Q32ZG2 Q32ZG7 Q32ZH1 Q32ZH4 Q32ZH5 Q32ZH7 Q4JEI2 Q4JEI3 Q4JEI5 Q4JEI6 Q4JEI8 Q4JEI9 Q62714 Q62715 Q9Z1F1	Defa Defa-rs1 Defa10 Defa11 Defa24 Defa31 Defa6 Defa8 Defa9 Defal1 Defb1 Defb14 Defb17 Defb18 Defb2 Defb21 Defb24 Defb25 Defb28 Defb3 Defb30 Defb36 Defb4 Defb41 Defb43 Defcr4 ENSRNOG00000064390 Np4 Rd5
Complex IV assembly	Coenzyme Q-binding protein COQ10 homolog B, mitochondrial Coenzyme Q10A Cytochrome c oxidase assembly factor 3 Cytochrome c oxidase assembly factor COX18 Cytochrome c oxidase assembly homolog COX15 Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase copper chaperone COX11 Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 4 isoform 2, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 6C-2 Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit 8C, mitochondrial Mitochondrial import inner membrane translocase subunit Tim21 Small integral membrane protein 20 Surfeit locus protein 1 Synthesis of cytochrome C oxidase 1 Thymidine phosphorylase Transmembrane protein 177	A0A0G2JYY6 A0A8I5ZSY5 A0A8I5ZWG1 C0HLM6 D3Z8B0 D3Z9I1 D3ZNJ0 D4A414 D4A568 G3V985 P00406 P05503 P10888 P11240 P11951 P80431 P80432 P80433 Q4KM93 Q5I0I9 Q5U2X7 Q5XFV8 Q7TNN2 Q91Y94 Q9QXU2	COX2 Coa3 Coi Coii Coq10a Coq10b Cox11 Cox14 Cox15 Cox16 Cox18 Cox20 Cox4 Cox4a Cox4b Cox4i1 Cox4i2 Cox5a Cox6c Cox6c2 Cox7b Cox7c Cox7c1 Cox8 Cox8a Cox8c Cox8l LOC100911779 LOC120096563 Mt-co1 Mt-co2 Mtco1 Mtco2 Sco1 Smim20 Surf-1 Surf1 Tim21 Timm21 Tmem177 Tymp
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 P2X purinoceptor 1 P2X purinoceptor 2 P2X purinoceptor 3 P2X purinoceptor 4 P2X purinoceptor 5 P2X purinoceptor 6 P2X purinoceptor 7 Short transient receptor potential channel 3 Transient receptor potential cation channel, subfamily C, member 7	F1LQF7 P29994 P29995 P47824 P49653 P49654 P51577 P51578 P51579 Q63269 Q64663 Q9JMI9	Insp3r Itpr1 Itpr2 Itpr3 P2rx1 P2rx2 P2rx3 P2rx4 P2rx5 P2rx6 P2rx7 P2rxl1 Trpc3 Trpc7 Trrp3
Generic Transcription Pathway	C2H2-type domain-containing protein Gonadotropin inducible ovarian transcription factor 1 KRAB-A domain containing 1 LOC680200 protein Neurotrophin receptor-interacting factor 1 RGD1565622 Regulator of sex limited protein 1 Similar to expressed sequence AI449175 Similar to regulator of sex-limitation candidate 16 Transcription intermediary factor 1-beta Uncharacterized LOC102556092 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vomeronasal 1 receptor, F4-like Zinc finger and SCAN domain containing 25 Zinc finger protein 111 Zinc finger protein 112 Zinc finger protein 12 Zinc finger protein 133 Zinc finger protein 13 Zinc finger protein 141 Zinc finger protein 143 Zinc finger protein 157 Zinc finger protein 169 Zinc finger protein 184 Zinc finger protein 189 Zinc finger protein 18 Zinc finger protein 1 Zinc finger protein 202 Zinc finger protein 212 Zinc finger protein 213 Zinc finger protein 239-like Zinc finger protein 248 Zinc finger protein 263 Zinc finger protein 267 Zinc finger protein 26 Zinc finger protein 273 like, pseudogene 1 Zinc finger protein 282 Zinc finger protein 286A Zinc finger protein 28 Zinc finger protein 2 Zinc finger protein 317 Zinc finger protein 324 Zinc finger protein 354A Zinc finger protein 354C Zinc finger protein 37, pseudogene 1 Zinc finger protein 382 Zinc finger protein 386 (Kruppel-like) Zinc finger protein 394 Zinc finger protein 398 Zinc finger protein 39 Zinc finger protein 419-like Zinc finger protein 420 Zinc finger protein 426 Zinc finger protein 43-like Zinc finger protein 431-like Zinc finger protein 431-like Zinc finger protein 445 Zinc finger protein 446 Zinc finger protein 45-like Zinc finger protein 454 Zinc finger protein 455 Zinc finger protein 458 Zinc finger protein 472 Zinc finger protein 473 Zinc finger protein 496 Zinc finger protein 52 Zinc finger protein 54 Zinc finger protein 560 Zinc finger protein 563 Zinc finger protein 566 Zinc finger protein 583 Zinc finger protein 605 Zinc finger protein 606 Zinc finger protein 612 Zinc finger protein 617 Zinc finger protein 641 Zinc finger protein 647 Zinc finger protein 655 Zinc finger protein 658-like Zinc finger protein 658 Zinc finger protein 665-like Zinc finger protein 667 Zinc finger protein 668 Zinc finger protein 688 Zinc finger protein 689 Zinc finger protein 689 Zinc finger protein 68 Zinc finger protein 703 Zinc finger protein 704 Zinc finger protein 706 Zinc finger protein 707-like 1 Zinc finger protein 709-like 1 Zinc finger protein 709-like Zinc finger protein 709-like Zinc finger protein 709-like Zinc finger protein 709-like Zinc finger protein 709-like Zinc finger protein 710 Zinc finger protein 715 Zinc finger protein 717 Zinc finger protein 728-like Zinc finger protein 740 Zinc finger protein 746 Zinc finger protein 748, pseudogene 1 Zinc finger protein 74 Zinc finger protein 750 Zinc finger protein 764 like 1 Zinc finger protein 764 Zinc finger protein 770 Zinc finger protein 773, pseudogene 1 Zinc finger protein 775 Zinc finger protein 780B, pseudogene 1 Zinc finger protein 799 Zinc finger protein 804B Zinc finger protein 839 Zinc finger protein 845 like, pseudogene 1 Zinc finger protein 846 Zinc finger protein 846 Zinc finger protein 850-like Zinc finger protein 850-like Zinc finger protein 866 Zinc finger protein 867 Zinc finger protein 869 Zinc finger protein 870 Zinc finger protein 883-like Zinc finger protein 90 Zinc finger protein 91-like Zinc finger protein 939 Zinc finger protein 954 Zinc finger protein OZF-like Zinc finger protein OZF-like Zinc finger protein interacting with K protein 1 Zinc finger protein with KRAB and SCAN domains 1 Zinc finger protein Zinc finger with KRAB and SCAN domains 3 Zinc finger with KRAB and SCAN domains 4 Zinc finger with KRAB and SCAN domains 5 Zinc finger with KRAB and SCAN domains 7 Zinc finger with KRAB and SCAN domains 8	A0A0G2JUS3 A0A0G2JW96 A0A0G2JWH7 A0A0G2JWU0 A0A0G2JWY4 A0A0G2K008 A0A0G2K0R0 A0A0G2K1A1 A0A0G2K1C4 A0A0G2K1C7 A0A0G2K1H6 A0A0G2K2I4 A0A0G2K379 A0A0G2K390 A0A0G2K3T8 A0A0G2K492 A0A0G2K8C6 A0A0G2K8T1 A0A0G2K951 A0A0G2K9M2 A0A8I5ZJF6 A0A8I5ZLH8 A0A8I5ZPP3 A0A8I5ZQN7 A0A8I5ZQZ7 A0A8I5ZS86 A0A8I5ZUL1 A0A8I5ZWP1 A0A8I5ZZL4 A0A8I6A0Y8 A0A8I6A3B5 A0A8I6A5Q4 A0A8I6A6J6 A0A8I6A7U8 A0A8I6A933 A0A8I6AAN4 A0A8I6ACG2 A0A8I6ACN9 A0A8I6ADN5 A0A8I6AGR4 A0A8I6AHN9 A0A8I6AIG3 A0A8I6AJD3 A0A8I6AL30 A0A8I6ALI6 A0A8I6AMT7 A0A8I6AP07 A0A8I6AP48 A0A8I6AQ11 A0A8I6AQ54 A0A8I6AQX0 A0A8I6AS09 A0A8I6G6C2 A0A8I6G6X3 A0A8I6G862 A0A8I6GKB8 A0A8I6GL47 A0A8J8YSH5 A0JPL0 A1L1L7 B1WBX4 B2RZ85 D3Z901 D3Z9A8 D3ZAB7 D3ZAK3 D3ZB41 D3ZB44 D3ZCK0 D3ZGH2 D3ZKK4 D3ZLR3 D3ZM47 D3ZQ68 D3ZRX1 D4A171 D4A286 D4A296 D4A2C1 D4A327 D4A3X9 D4A4V7 D4A514 D4A5T4 D4A6L5 D4A704 D4A7C1 D4A7G1 D4ABF5 D4ACK9 E9PTG0 F1LPY3 F1LQU1 F1LSG4 F1LSH5 F1LT76 F1LTH0 F1LTY6 F1LU95 F1LVJ0 F1LVS9 F1LWS7 F1LYK4 F1LZG2 F1M076 F1M0F0 F1M1B9 F1M278 F1M2B6 F1M829 F1M9J2 F1MAL7 F7DP88 F7FQD8 G3V6U6 G3V8H6 G3V9G6 G3V9J4 M0R3N9 M0R5W9 M0R7K4 M0R8P8 M0R904 M0RA43 M0RAT5 M0RCK0 M0RCQ9 M0RDI4 M0RDY1 O08629 Q02975 Q4KLI1 Q4V8A8 Q4V8E9 Q5MYW4 Q5U2X3 Q5XIU2 Q642B9 Q6P6Q8 Q7TPB3 Q99PJ7 Q9EPU7 Q9Z2K3	9130023H24Rik AABR07002893.1 ENSRNOG00000064392 ENSRNOG00000065506 ENSRNOG00000067347 ENSRNOG00000067761 ENSRNOG00000069512 ENSRNOG00000069557 Giot1 Hit39 Kap1 Kid1 Krba1 LOC100359967 LOC100365363 LOC100366023 LOC100909688 LOC100910577 LOC100911224 LOC100912683 LOC100912787 LOC102546572 LOC102546648 LOC102547287 LOC102547412 LOC102548695 LOC102550291 LOC102550944 LOC102552527 LOC102553866 LOC102555672 LOC102556092 LOC103691238 LOC108348090 LOC108348123 LOC108348125 LOC108348224 LOC108348302 LOC120094815 LOC120094816 LOC134478820 LOC134478826 LOC361487 LOC680200 LOC682206 LOC682834 LOC688328 MGC72612 Mip1 Mipu1 Nrif1 Prdm5 RGD1561413 RGD1561832 RGD1566325 RGD1566386 Rlzfy Rsl1 Staf Tcf17 Tif1b Trim28 Zfp1 Zfp110 Zfp111 Zfp112 Zfp12 Zfp13 Zfp133 Zfp141 Zfp143 Zfp157 Zfp160 Zfp167 Zfp169 Zfp18 Zfp184 Zfp189 Zfp192 Zfp2 Zfp202 Zfp212 Zfp213 Zfp23 Zfp239l1 Zfp248 Zfp26 Zfp263 Zfp267 Zfp273l-ps1 Zfp28 Zfp282 Zfp286a Zfp317 Zfp324 Zfp354a Zfp354c Zfp37-ps1 Zfp382 Zfp386 Zfp39 Zfp394 Zfp398 Zfp420 Zfp426 Zfp445 Zfp446 Zfp455 Zfp455l1 Zfp458 Zfp470 Zfp472 Zfp473 Zfp496 Zfp498 Zfp52 Zfp534l2 Zfp535 Zfp54 Zfp560 Zfp563 Zfp566 Zfp58 Zfp583 Zfp599 Zfp605 Zfp606 Zfp612 Zfp617 Zfp629 Zfp641 Zfp647 Zfp655 Zfp658 Zfp664 Zfp667 Zfp668 Zfp677 Zfp68 Zfp688 Zfp689 Zfp703 Zfp704 Zfp706 Zfp707 Zfp707l1 Zfp708 Zfp709l1 Zfp709l2 Zfp710 Zfp715 Zfp717 Zfp74 Zfp746 Zfp748 Zfp748-ps1 Zfp764 Zfp764l1 Zfp77 Zfp770 Zfp772 Zfp773-ps1 Zfp775 Zfp78 Zfp780b-ps1 Zfp788 Zfp790l2 Zfp799 Zfp80 Zfp804b Zfp808l3 Zfp839 Zfp846 Zfp866 Zfp867 Zfp868 Zfp869 Zfp87 Zfp870 Zfp874b Zfp9 Zfp90 Zfp939 Zfp94 Zfp94l1 Zfp950 Zfp950l11 Zfp950l12 Zfp950l2 Zfp950l4 Zfp951 Zfp954 Zfp961 Zfp973 Zfp99 Zik1 Zkscan1 Zkscan3 Zkscan4 Zkscan5 Zkscan7 Zkscan8 Znf143 Znf18 Znf248 Znf354a Znf354b Znf354c Znf382 Znf394 Znf426 Znf454 Znf667 Znf689 Znf740 Znf750 Znf770 Znf773 Znf845l-ps1 Znf846 Zscan25
Abacavir transmembrane transport	Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	O88446 Q63089 Q9R0W2	Oct1 Oct2 Oct3 Slc22a1 Slc22a2 Slc22a3
Cholesterol biosynthesis	3-hydroxy-3-methylglutaryl-coenzyme A reductase 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 Acetyl-CoA acetyltransferase, cytosolic Delta(14)-sterol reductase LBR Delta(24)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Lanosterol 14-alpha demethylase Lanosterol synthase Methylsterol monooxygenase 1 Mevalonate kinase Phosphomevalonate kinase Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 Protein ARV Squalene monooxygenase Squalene synthase Sterol regulatory element-binding protein 1 Sterol regulatory element-binding protein 2 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating isopentenyl-diphosphate Delta-isomerase	A0A8I6AEP6 D3ZTJ1 D3ZVY0 O35532 O35760 P05369 P17256 P17425 P48450 P51639 P52020 P56720 Q02769 Q3T1I5 Q5BQE6 Q5PPL3 Q5RK24 Q5XI22 Q62904 Q62967 Q64654 Q66H88 Q6F596	AABR07021955.1 Acat2 Arv1 Cyp51 Cyp51a1 Dhcr24 Erg1 Fdft1 Fdps Ggps1 Hmgcr Hmgcs Hmgcs1 Hsd17b7 Idi1 Idi2l3 Lbr Lss Mpd Msmo1 Mvd Mvk Nsdhl Osc Plpp6 Pmvk RGD1564999 Sc4mol Sqle Srebf1 Srebf2 Srebp1
Nicotinate metabolism	5'-nucleotidase ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Glutamine-dependent NAD(+) synthetase NAD kinase 2, mitochondrial NAD(+) kinase Nicotinamide riboside kinase 1 Nicotinamide-nucleotide adenylyltransferase Nicotinamide-nucleotide adenylyltransferase Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 Nicotinate-nucleotide pyrophosphorylase [carboxylating]	A0A8I5ZV91 A0A8I6AFT7 F7F588 P21588 Q0HA29 Q1HCL7 Q5I0M2 Q63072 Q64244 Q6AY91 Q812E8	Bst1 Cd38 Mnadk Nadk Nadk2 Nadkd1 Nadsyn1 Nmnat1 Nmnat2 Nmnat3 Nmrk1 Nrk1 Nt5 Nt5e Nte Qns1 Qprt
IRAK2 mediated activation of TAK1 complex	Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 P0C8E4 P0CG51 P62982 Q4QQS0 Q5U303 Q63429	Irak2 LOC100360645 Map3k7 Map3k7ip2 Rps27a Tab1 Tab2 Tab3 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
cGMP effects	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A Inositol 1,4,5-triphosphate receptor associated 1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Phosphodiesterase cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-dependent protein kinase 2 cGMP-dependent protein kinase cGMP-specific 3',5'-cyclic phosphodiesterase	A0A8I6A416 A0A8I6A9E8 D3ZDF3 O54735 P29994 Q01062 Q01066 Q64595 Q8QZV1 Q8VID6 Q9QYJ6	AABR07006724.1 Insp3r Irag1 Itpr1 Mrvi1 Pde10a Pde11a Pde1a Pde1b Pde1b1 Pde2a Pde5 Pde5a Pde9a Prkg1 Prkg2
activated TAK1 mediates p38 MAPK activation	Interleukin-1 receptor-associated kinase-like 2 MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 Mapk11 protein Mitogen-activated protein kinase 14 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleotide-binding oligomerization domain containing 1 Nucleotide-binding oligomerization domain containing 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 variant 1 mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase non-specific serine/threonine protein kinase	A0A0G2JYX9 A0A0G2K4Z7 A0A0U1RRU5 A0A8I6A3Q1 A0A8I6ABN5 A0A8I6AH74 B5DF45 D4A3U7 D4ADT7 G3V783 M0R7E7 P0C8E4 P70618 Q4QQS0 Q5U303 Q66H84 Q6TMG5 Q80ZF4 Q925D6	Csbp1 Csbp2 ENSRNOG00000067007 Ikbkg Irak1 Irak2 Map2k3 Map2k6 Map3k7 Map3k7ip2 Mapk11 Mapk14 Mapkapk2 Mapkapk3 Mkk6 Nemo Nod1 Nod2 Ripk2 Tab1 Tab2 Tab3 Traf6
G alpha (s) signalling events	3',5'-cyclic-AMP phosphodiesterase 4A 3',5'-cyclic-AMP phosphodiesterase 4C (Fragment) 3',5'-cyclic-AMP phosphodiesterase 4D Beta-2 adrenergic receptor Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B G protein-coupled receptor kinase 3 G protein-coupled receptor kinase 5 G protein-coupled receptor kinase 6 High affinity 3',5'-cyclic-AMP phosphodiesterase 7A (Fragment) Phosphodiesterase Phosphodiesterase Phosphodiesterase Phosphodiesterase cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B	A0A8I5ZTX5 A0A8I5ZWQ4 A0A8I6A416 O08593 P10608 P14270 P14644 P26817 P26819 P29066 P29067 P54748 P97711 Q01062 Q01066 Q62833 Q62865 Q63085 Q76KC6 Q8VID6 Q9QYJ6	Adrb2 Adrb2r Adrbk1 Adrbk2 Arrb1 Arrb2 Dpde1 Gprk5 Gprk6 Grk2 Grk3 Grk5 Grk6 Pde10a Pde11a Pde1a Pde1b Pde1b1 Pde2a Pde3a Pde3b Pde4a Pde4c Pde4d Pde7a Pde7b Pde8a Pde8b RNPDE8A
Formation of the cornified envelope	Caspase 14 Chymotrypsin-like elastase family member 2A Corneodesmosin Desmocollin 1 Desmocollin 2 Desmocollin 3 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein-4 Desmoplakin Envoplakin Junction plakoglobin Kallikrein k Kallikrein l Kallikrein m Kallikrein related-peptidase 5 Kallikrein-8 Kazrin Lipase Lipase Lipase P53 apoptosis effector related to PMP22 Periplakin Plakophilin 1 Plakophilin 3 Plakophilin 4 Plakophilin-2 Protein-glutamine gamma-glutamyltransferase K Repetin Serine peptidase inhibitor, Kazal type 5 Serine protease inhibitor Kazal-type 6 Small proline-rich protein 3 Stefin A2-like 3	A0A0G2K230 A0A0G2K430 A0A0G2KA90 A0A8I5ZKH8 A0A8I6A880 A0A8I6AG90 A0A8I6GLK6 B2GVC0 D3ZD22 D3ZET2 D3ZHQ6 D3ZJ50 D3ZJ70 D3ZJR7 D3ZL74 D3ZM39 D3ZRA7 D3ZRF0 D3ZY51 D3ZZ65 D4A5T8 D4A9L7 D4AA61 F1LMV6 F1M091 F1M7L9 G3V765 O88780 P00774 P23606 Q5FWS6 Q6IE47 Q6P0K8 Q6W3B0	AABR07044375.1 Bsp1 Casp14 Cdsn Cela2a Dsc1 Dsc2 Dsc3 Dsg1 Dsg2 Dsg3 Dsg4 Dsp Ela2 Ela2a Evpl Jup Kaz Kazn Klk12 Klk13 Klk14 Klk5 Klk8 Klnk Klnl Klnm Lipk Lipm Lipn Nrpn Perp Pg Pkp1 Pkp2 Pkp3 Pkp4 Ppl Prss19 Rptn Spink5 Spink5l1 Spink6 Sprr3 Stfa2l3 Tgm1
NRIF signals cell death from the nucleus	Beta-nerve growth factor Centromere protein R Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Sequestosome-1 TNF receptor-associated factor 6 Tumor necrosis factor receptor superfamily member 16 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I6A5Y3 B5DF45 F7EYZ3 O08623 O88777 P07174 P0CG51 P25427 P62982 P97887 Q5U1Z7 Q63429 Q6QI68 Q8CGU6	Aph1a Cenpr Itgb3bp LOC100360645 Ncstn Ngf Ngfb Ngfr Nrif3 Ps2 Psen1 Psen2 Psenen Psnl1 Psnl2 Rps27a Sqstm1 Tnfrsf16 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Zip
TNFs bind their physiological receptors	EDAR-associated death domain Ectodysplasin A2 receptor Ectodysplasin-A receptor Ectodysplasin-A Lymphotoxin-alpha TNF receptor superfamily member 13B TNF receptor superfamily member 14 TNF receptor superfamily member 17 TNF receptor superfamily member 18 TNF receptor superfamily member 25 TNF receptor superfamily member 9 TNF superfamily member 13 TNF superfamily member 13b TNF superfamily member 18 TNF superfamily member 8 TNF superfamily member 9 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 15 Tumor necrosis factor ligand superfamily member 4 Tumor necrosis factor receptor superfamily member 11B Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor superfamily member 4 Tumor necrosis factor receptor superfamily member 8	A0A096MIW0 A0A096MJP5 A0A8I6ATG2 A0A8J8XC20 D3ZFD8 D3ZGP2 D3ZKQ8 D4A3I1 D4ADP7 F1LX35 F1LYE0 F7FFS7 M0R3V3 O08727 P15725 P22934 P97525 Q06332 Q4V895 Q80WE6 Q80WY6 Q8K3Y7 Q9ESE2 Q9Z2P3	Cd30 Eda Eda2r Edar Edaradd Lta Opg Opgl Ox40 Ox40l Rankl Tl1 Tnfb Tnfr-1 Tnfr1 Tnfr2 Tnfrsf11b Tnfrsf13b Tnfrsf14 Tnfrsf17 Tnfrsf18 Tnfrsf1a Tnfrsf1b Tnfrsf25 Tnfrsf4 Tnfrsf8 Tnfrsf9 Tnfsf1 Tnfsf11 Tnfsf13 Tnfsf13b Tnfsf15 Tnfsf18 Tnfsf4 Tnfsf8 Tnfsf9 Tnlg3a Tnlg5a Trance Txgp1 Txgp1l Vegi
NOD1/2 Signaling Pathway	Angio-associated, migratory cell protein Baculoviral IAP repeat-containing 2 Baculoviral IAP repeat-containing 3 Caspase-1 Caspase-2 Caspase-8 Caspase-9 E3 ubiquitin-protein ligase Mapk11 protein Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleotide-binding oligomerization domain containing 1 Nucleotide-binding oligomerization domain containing 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 Ubiquitin carboxyl-terminal hydrolase CYLD mitogen-activated protein kinase kinase ubiquitinyl hydrolase 1	A0A0G2JTI9 A0A0G2K4Z7 A0A0U1RRU5 A0A8I5ZZU1 A0A8I6ABN5 A0A8I6AH74 A0A8I6AL23 D4A3U7 D4ADT7 G3V783 G3V7V2 P0C8E4 P43527 P55215 P70618 Q5U303 Q63538 Q66H62 Q6P6S1 Q6TMG5 Q925D6 Q9JHK1 Q9JHX4 Q9WTY9	Aamp Birc2 Birc3 Casp1 Casp2 Casp8 Casp9 Casp9_v1 Csbp1 Csbp2 Cyld Cyld1 Ich1 Ikbkg Il1bc Il1bce Itch Map2k6 Map3k7 Map3k7ip2 Mapk11 Mapk12 Mapk13 Mapk14 Mkk6 Nemo Nod1 Nod2 RNCASP9 Ripk2 Sapk3 Tab1 Tab2 Tab3 Tnfaip3
RND2 GTPase cycle	Aldehyde dehydrogenase family 3 member A2 Ankyrin repeat domain containing 26 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 Bridge-like lipid transfer protein family member 3B Caveolin-1 Cytoskeleton-associated protein 4 DEP domain containing 1B Desmoglein 1 Discs large MAGUK scaffold protein 5 Dystonin Family with sequence similarity 83, member B Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Formin-binding protein 1 Golgin A3 Inactive tyrosine-protein kinase PRAG1 Kinase D-interacting substrate of 220 kDa Kinectin 1 Kinesin family member 14 Mucin-13 Nischarin Nuclear migration protein nudC Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plakophilin 4 Plexin D1 RNA binding motif protein 39 RNA-binding motif protein, X chromosome Rho GTPase activating protein 1 Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Rho family GTPase 2 Scribble planar cell polarity protein Thioredoxin-like protein 1 Transferrin receptor protein 1 Tyrosine-protein phosphatase non-receptor type 13 UBX domain-containing protein 11 Vang-like protein 2 Vang-like protein receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A0G2JYR5 A0A0G2K7N9 A0A8I5ZQD4 A0A8I6A4W2 A0A8I6A880 A0A8I6GLX4 A0A8J8XIU8 D3ZBN3 D3ZE01 D3ZF70 D3ZH41 D3ZKC8 D3ZLD5 D3ZM39 D3ZMK9 D3ZWS0 D4A244 D4AA32 D4AA77 G3V9S3 M0R3T8 M0R8V0 P30839 P41350 P81128 P84889 P97881 Q4G017 Q4V898 Q52RG8 Q5HZE6 Q5XFW6 Q63525 Q63787 Q63788 Q7TNY1 Q8R511 Q8R512 Q920J4 Q99376 Q9EQG6	Aldh3a2 Aldh4 Ankrd26 Arhgap1 Arhgap35 Arhgap5 Arms Bltp3b Cav Cav1 Ckap4 Depdc1b Dlg5 Dsg1 Dst Epha2 Fam83b Fbp17 Fnbp1 Frs2 Frs3 Golga3 Grlf1 Kidins220 Kif14 Ktn1 Muc13 Nisch Nudc P190A Pik3r1 Pik3r2 Pkp4 Plxnd1 Prag1 Pragmin Ptpn13 Rbm39 Rbmx Rbmxrt Rnd2 Scrib Snt2 Soc Tfrc Tnfaip1 Trfr Trp Txnl1 Ubxd5 Ubxn11 Uhrf1bp1l Vangl1 Vangl2 Wdr6 p190ARHOGAP
Signaling by Erythropoietin	Erythropoietin receptor Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	F1MAL5 Q07014 Q07303 Q62689	Epor Irs2 Jak2 Lyn
Collagen degradation	5-phosphohydroxy-L-lysine phospho-lyase 72 kDa type IV collagenase Cathepsin B Cathepsin D Cathepsin K Collagen type XIII alpha 1 chain Collagen type XIX alpha 1 chain Collagen type XV alpha 1 chain Collagen type XVIII alpha 1 chain Collagen type XXV alpha 1 chain Collagen type XXVI alpha 1 chain Collagenase 3 (Fragment) Furin Macrophage metalloelastase Matrilysin Matrix metallopeptidase 15 Matrix metallopeptidase 20 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Neutrophil collagenase Similar to Cathepsin L precursor (Major excreted protein) (MEP) Stromelysin-1 Stromelysin-2 Transmembrane serine protease 6 interstitial collagenase trypsin trypsin	A0A0G2JV12 A0A0G2K2Q8 A0A0G2K8N4 A0A8I5ZME9 A0A8I6G6J0 A0A8I6GLR1 A0A8J8XD81 B5DFD5 D3ZCG5 D3ZCQ0 D3ZKC3 D3ZQV0 D3ZXD9 M0RAM0 O35186 O88766 P00787 P03957 P07152 P23097 P23377 P24268 P33436 P50280 P50282 Q10739 Q63341	Col13a1 Col15a1 Col18a1 Col19a1 Col25a1 Col26a1 Cts7l2 Ctsb Ctsd Ctsk Ctsll3 Fur Furin LOC100365995 LOC100909752 LOC103690164 LOC687064 Mmel Mmp-7 Mmp1 Mmp10 Mmp12 Mmp13 Mmp14 Mmp15 Mmp1a Mmp2 Mmp20 Mmp3 Mmp7 Mmp8 Mmp9 Mtmmp Pcsk3 Phykpl Prss3 RGD1308751 Tmprss6 Try4 Try5
ARMS-mediated activation	Adapter molecule crk Beta-nerve growth factor High affinity nerve growth factor receptor Kinase D-interacting substrate of 220 kDa Ras-related protein Rap-1A	P25427 P35739 P62836 Q63768 Q9EQG6	Arms Crk Crko Kidins220 Krev1 Ngf Ngfb Ntrk1 Rap1a Trk Trka
Depolymerization of the Nuclear Lamina	CTD nuclear envelope phosphatase 1 Cyclin-dependent kinase 1 Emerin G2/mitotic-specific cyclin-B1 Lamin-B1 Nuclear envelope phosphatase-regulatory subunit 1 Prelamin-A/C Protein kinase C alpha type Protein kinase C beta type RNA binding motif protein 39 phosphatidate phosphatase phosphatidate phosphatase phosphatidate phosphatase	A0A0G2JW03 A0A0G2JY62 A0A8I6AUU1 A0A8J8XIU8 D3ZJA8 P05696 P30277 P39951 P48679 P68403 P70615 Q3B7T6 Q63190	Ccnb1 Cdc2 Cdc2a Cdk1 Cdkn1 Cnep1r1 Ctdnep1 Dullard Emd Lmn1 Lmna Lmnb1 Lpin1 Lpin2 Lpin3 Pkca Pkcb Prkca Prkcb Prkcb1 Rbm39 Tmem188
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	BCL2 interacting protein 3 like Metalloreductase STEAP3 Serine-protein kinase ATM Zinc finger protein 420	A0A8I6AG85 D3Z901 D4ACL8 Q5RKL5	Atm Bnip3l LOC134478826 Steap3 Zfp420

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