GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **751 - 775** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	GlyTouCan ID
Truncations of AMER1 destabilize the destruction complex	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX
ER Quality Control Compartment (ERQC)	Derlin-2 E3 ubiquitin-protein ligase AMFR E3 ubiquitin-protein ligase MARCHF6 E3 ubiquitin-protein ligase RNF103 E3 ubiquitin-protein ligase RNF139 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 E3 ubiquitin-protein ligase TRIM13 E3 ubiquitin-protein ligase synoviolin ER degradation-enhancing alpha-mannosidase-like protein 1 ER degradation-enhancing alpha-mannosidase-like protein 2 ER degradation-enhancing alpha-mannosidase-like protein 3 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Polyubiquitin-B Polyubiquitin-C Protein OS-9 Protein sel-1 homolog 1 UDP-glucose UDP-glucose Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00237 O60337 O60858 P0CG47 P0CG48 P62979 P62987 Q13438 Q86TM6 Q8WU17 Q92611 Q96GF1 Q99942 Q9BV94 Q9BZQ6 Q9GZP9 Q9NYU1 Q9NYU2 Q9UBV2 Q9UKM7 Q9UKV5	AMFR C1orf22 C20orf31 C20orf49 DER2 DERL2 EDEM EDEM1 EDEM2 EDEM3 FLANA G16 GT HRD1 KIAA0212 KIAA0597 KIAA1810 LEU5 MAN1B1 MARCH6 MARCHF6 NG2 OS9 RFP2 RMA1 RNF103 RNF139 RNF176 RNF185 RNF45 RNF5 RNF77 RPS27A SEL1L SYVN1 TEB4 TRC8 TRIM13 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UGCGL1 UGCGL2 UGGT UGGT1 UGGT2 UGT1 UGT2 UGTR ZFP103	G70323CJ G93575MM
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	26S proteasome regulatory subunit 4 Cytosolic endo-beta-N-acetylglucosaminidase Derlin-1 E3 ubiquitin-protein ligase AMFR Glucosidase 2 subunit beta Malectin Mannosyl-oligosaccharide glucosidase Neutral alpha-glucosidase AB Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Polyubiquitin-B Polyubiquitin-C Transitional endoplasmic reticulum ATPase UBX domain-containing protein 1 UV excision repair protein RAD23 homolog B Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P14314 P54727 P55072 P62191 P62979 P62987 Q04323 Q13724 Q14165 Q14697 Q8NFI3 Q96IV0 Q9BUN8 Q9UKV5	AMFR DER1 DERL1 ENGASE G19P1 G2AN GANAB GCS1 HEL-220 HEL-S-70 KIAA0088 KIAA0152 MLEC MOGS NGLY1 PNG1 PRKCSH PSMC1 RAD23B RNF45 RPS27A SAKS1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBXN1 VCP	G03934XO G25577BM G28233ME G51034LA G58161NS G86419OL
RUNX3 regulates p14-ARF	Bromodomain-containing protein 2 Core-binding factor subunit beta G1/S-specific cyclin-D1 GTPase KRas Histone acetyltransferase p300 Histone deacetylase 4 Runt-related transcription factor 1 Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein	P01116 P01137 P24385 P25440 P56524 Q01196 Q09472 Q13761 Q13951	AML1 AML2 BCL1 BRD2 CBFA2 CBFA3 CBFB CCND1 EP300 HDAC4 KIAA0288 KIAA9001 KRAS KRAS2 P300 PEBP2A3 PRAD1 RASK2 RING3 RUNX1 RUNX3 TGFB TGFB1
RUNX1 regulates expression of components of tight junctions	Claudin-5 Core-binding factor subunit beta Occludin Runt-related transcription factor 1 Tight junction protein ZO-1	O00501 Q01196 Q07157 Q13951 Q16625	AML1 AWAL CBFA2 CBFB CLDN5 OCLN RUNX1 TJP1 TMVCF ZO1
RUNX1 regulates transcription of genes involved in WNT signaling	Axin-1 Core-binding factor subunit beta Estrogen receptor Forkhead box protein P3 R-spondin-3 Runt-related transcription factor 1	O15169 P03372 Q01196 Q13951 Q9BXY4 Q9BZS1	AML1 AXIN AXIN1 CBFA2 CBFB ESR ESR1 FOXP3 IPEX NR3A1 PWTSR RSPO3 RUNX1 THSD2
RUNX1 regulates estrogen receptor mediated transcription	Axin-1 BTB/POZ domain-containing protein KCTD6 Core-binding factor subunit beta Estrogen receptor Glycerol-3-phosphate acyltransferase 1, mitochondrial Runt-related transcription factor 1	O15169 P03372 Q01196 Q13951 Q8NC69 Q9HCL2	AML1 AXIN AXIN1 CBFA2 CBFB ESR ESR1 GPAM GPAT1 KCTD6 KIAA1560 NR3A1 RUNX1
RUNX1 regulates transcription of genes involved in BCR signaling	Core-binding factor subunit beta ETS-related transcription factor Elf-1 ETS-related transcription factor Elf-2 Paired box protein Pax-5 Runt-related transcription factor 1 Tyrosine-protein kinase Blk	P32519 P51451 Q01196 Q02548 Q13951 Q15723	AML1 BLK CBFA2 CBFB ELF1 ELF2 NERF PAX5 RUNX1
Organic cation transport	Organic cation/carnitine transporter 2 Regulatory solute carrier protein family 1 member 1 Runt-related transcription factor 1 Solute carrier family 22 member 15 Solute carrier family 22 member 16 Solute carrier family 22 member 18 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3 Solute carrier family 22 member 4	O15244 O15245 O75751 O76082 Q01196 Q86VW1 Q8IZD6 Q92681 Q96BI1 Q9H015	AML1 BWR1A BWSCR1A CBFA2 EMTH ETT FLIPT1 HET IMPT1 ITM OCT1 OCT2 OCT3 OCT6 OCTN1 OCTN2 ORCTL2 RSC1A1 RUNX1 SLC22A1 SLC22A15 SLC22A16 SLC22A18 SLC22A1L SLC22A2 SLC22A3 SLC22A4 SLC22A5 TSSC5 UT2H
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Cathepsin L2 Core-binding factor subunit beta Procathepsin L Runt-related transcription factor 1 Serpin B13 Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 4	O14543 O60911 P07711 P43235 Q01196 Q13951 Q8WXH5 Q9UIV8	AML1 CATL2 CBFA2 CBFB CIS3 CTSK CTSL CTSL1 CTSL2 CTSO CTSO2 CTSU CTSV PI13 RUNX1 SERPINB13 SOCS3 SOCS4 SOCS7 SSI3
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	CREB-binding protein Core-binding factor subunit beta Galectin-3 Granulocyte-macrophage colony-stimulating factor Protein kinase C beta type Runt-related transcription factor 1	P04141 P05771 P17931 Q01196 Q13951 Q92793	AML1 CBFA2 CBFB CBP CREBBP CSF2 GMCSF LGALS3 MAC2 PKCB PRKCB PRKCB1 RUNX1
RUNX1 regulates transcription of genes involved in interleukin signaling	Core-binding factor subunit beta ETS-related transcription factor Elf-1 Interleukin-3 Leukemia inhibitory factor receptor Runt-related transcription factor 1	P08700 P32519 P42702 Q01196 Q13951	AML1 CBFA2 CBFB ELF1 IL3 LIFR RUNX1
RUNX2 regulates genes involved in differentiation of myeloid cells	Core-binding factor subunit beta Galectin-3 Runt-related transcription factor 1	P17931 Q01196 Q13951	AML1 CBFA2 CBFB LGALS3 MAC2 RUNX1
RUNX3 regulates CDKN1A transcription	Cellular tumor antigen p53 Cyclin-dependent kinase inhibitor 1 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein Zinc finger homeobox protein 3	P01137 P04637 P38936 P84022 Q13485 Q13761 Q15911	AML2 ATBF1 C16orf47 CAP20 CBFA3 CDKN1 CDKN1A CIP1 DPC4 MADH3 MADH4 MDA6 P53 PEBP2A3 PIC1 RUNX3 SDI1 SMAD3 SMAD4 TGFB TGFB1 TP53 WAF1 ZFHX3
Binding of TCF/LEF:CTNNB1 to target gene promoters	Axin-2 Catenin beta-1 Lymphoid enhancer-binding factor 1 Myc proto-oncogene protein Runt-related transcription factor 3 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7	P01106 P35222 P36402 Q13761 Q9HCS4 Q9NQB0 Q9UJU2 Q9Y2T1	AML2 AXIN2 BHLHE39 CBFA3 CTNNB CTNNB1 LEF1 MYC PEBP2A3 RUNX3 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2
RUNX3 regulates WNT signaling	Catenin beta-1 G1/S-specific cyclin-D1 Lymphoid enhancer-binding factor 1 Myc proto-oncogene protein Runt-related transcription factor 3 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7	P01106 P24385 P35222 P36402 Q13761 Q9HCS4 Q9NQB0 Q9UJU2	AML2 BCL1 BHLHE39 CBFA3 CCND1 CTNNB CTNNB1 LEF1 MYC PEBP2A3 PRAD1 RUNX3 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2
RUNX3 regulates BCL2L11 (BIM) transcription	Bcl-2-like protein 11 Forkhead box protein O3 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Runt-related transcription factor 3	O43521 O43524 P84022 Q13485 Q13761	AML2 BCL2L11 BIM CBFA3 DPC4 FKHRL1 FOXO3 FOXO3A MADH3 MADH4 PEBP2A3 RUNX3 SMAD3 SMAD4
RUNX3 regulates NOTCH signaling	CREB-binding protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 1 Protein jagged-1 Recombining binding protein suppressor of hairless Runt-related transcription factor 3 SNW domain-containing protein 1 Transcription factor HES-1	P46531 P78504 Q06330 Q09472 Q13495 Q13573 Q13761 Q14469 Q8IZL2 Q92585 Q92793 Q92830 Q92831 Q96JK9	AML2 BHLHB39 CBFA3 CBP CG1 CREBBP CXorf6 EP300 GCN5 GCN5L2 HES1 HL HRY IGKJRB IGKJRB1 JAG1 JAGL1 KAT2A KAT2B KIAA0200 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 NOTCH1 P300 PCAF PEBP2A3 RBPJ RBPJK RBPSUH RUNX3 SKIIP SKIP SNW1 TAN1
RUNX3 Regulates Immune Response and Cell Migration	Core-binding factor subunit beta Integrin alpha-4 Integrin alpha-L Osteopontin Runt-related transcription factor 3	P10451 P13612 P20701 Q13761 Q13951	AML2 BNSP CBFA3 CBFB CD11A CD49D ITGA4 ITGAL OPN PEBP2A3 RUNX3 SPP1
Regulation of RUNX3 expression and activity	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Core-binding factor subunit beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Histone acetyltransferase p300 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proto-oncogene tyrosine-protein kinase Src Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 P01137 P0CG47 P0CG48 P12931 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q00987 Q06323 Q09472 Q13200 Q13761 Q13951 Q15008 Q16401 Q8N726 Q92530 Q99436 Q99460 Q9HAU4 Q9HCE7 Q9UL46 Q9UNM6	AML2 C7orf76 CBFA3 CBFB CDKN2 CDKN2A DSS1 EP300 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIAA1625 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MDM2 MECL1 MIP224 MLM MOV34L MSS1 NU P300 PEBP2A3 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RING10 RING12 RPS27A RUNX3 SEM1 SHFDG1 SHFM1 SMURF1 SMURF2 SRC SRC1 SUG1 SUG2 TBP1 TBP7 TGFB TGFB1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
RUNX3 regulates RUNX1-mediated transcription	Core-binding factor subunit beta Runt-related transcription factor 3	Q13761 Q13951	AML2 CBFA3 CBFB PEBP2A3 RUNX3
RUNX3 regulates YAP1-mediated transcription	CCN family member 2 Runt-related transcription factor 3 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-4 Transcriptional enhancer factor TEF-5 WW domain-containing transcription regulator protein 1	P28347 P29279 P46937 Q13761 Q15561 Q15562 Q99594 Q9GZV5	AML2 CBFA3 CCN2 CTGF HCS24 IGFBP8 PEBP2A3 RTEF1 RUNX3 TAZ TCF13 TCF13L1 TEAD1 TEAD2 TEAD3 TEAD4 TEAD5 TEF1 TEF3 TEF4 TEF5 WWTR1 YAP1 YAP65
HDL clearance	Apolipoprotein A-I Cubilin Protein amnionless Vigilin	O60494 P02647 Q00341 Q9BXJ7	AMN APOA1 CUBN HBP HDLBP IFCR VGL
Defective AMN causes MGA1	Cobalamin binding intrinsic factor Cubilin Protein amnionless	O60494 P27352 Q9BXJ7	AMN CBLIF CUBN GIF IFCR IFMH
Defective CUBN causes MGA1	Cobalamin binding intrinsic factor Cubilin Protein amnionless	O60494 P27352 Q9BXJ7	AMN CBLIF CUBN GIF IFCR IFMH

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