GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **326 - 350** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Sorafenib-resistant PDGFR mutants	Platelet-derived growth factor receptor alpha	P16234	PDGFR2 PDGFRA RHEPDGFRA	Homo sapiens (human)
snRNP Assembly	Aladin E3 SUMO-protein ligase RanBP2 Gem-associated protein 2 Gem-associated protein 4 Gem-associated protein 5 Gem-associated protein 6 Gem-associated protein 7 Gem-associated protein 8 Methylosome protein WDR77 Methylosome subunit pICln Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Phosphorylated adapter RNA export protein Probable ATP-dependent RNA helicase DDX20 Protein SEC13 homolog Protein arginine N-methyltransferase 5 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D1 Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' Snurportin-1 Survival motor neuron protein Trimethylguanosine synthase mRNA export factor RAE1	A8CG34 O14744 O14893 O15504 O75694 O95149 P12270 P14678 P35658 P37198 P49790 P49792 P52298 P54105 P55735 P57678 P57740 P62304 P62306 P62308 P62314 P62316 P62318 P78406 Q09161 Q12769 Q16637 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8TEQ6 Q8WUM0 Q8WXD5 Q92621 Q96HA1 Q96RS0 Q99567 Q9BQA1 Q9BTX1 Q9BW27 Q9H814 Q9H840 Q9NRG9 Q9NWZ8 Q9UHI6 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CBP20 CBP80 CG1 CLCI CLNS1A COD D3S1231E DDX20 DP103 FAM51A1 GEMIN2 GEMIN3 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 HCA137 HRMT1L5 IBP72 ICLN JBP1 KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MEP50 MP44 MRNP41 NCBP NCBP1 NCBP2 NCOA6IP NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PBSCF PBSCG PCNT1 PHAX PIMT POM121 POM121A POM121C PRMT5 RAE1 RANBP2 RNUT1 RNUXA SEC13 SEC13A SEC13L1 SEC13R SIP1 SKB1 SMN SMN1 SMN2 SMNC SMNT SNRPB SNRPB1 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN SPN1 TGS1 TMEM48 TPR WD45 WDR77	Homo sapiens (human)
MTF1 activates gene expression	Beta-synuclein Cysteine and glycine-rich protein 1 Metal regulatory transcription factor 1	P21291 Q14872 Q16143	CSRP CSRP1 CYRP MTF1 SNCB	Homo sapiens (human)
RNA Polymerase II Transcription Elongation	AF4/FMR2 family member 4 CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 ELL-associated factor 1 ELL-associated factor 2 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Parafibromin Protein AF-9 Protein ENL Protein IWS1 homolog RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase II-associated factor 1 homolog RNA polymerase-associated protein CTR9 homolog RNA polymerase-associated protein LEO1 RNA polymerase-associated protein RTF1 homolog Superkiller complex protein 8 Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription elongation factor SPT6	O00267 O15514 O60563 O60583 O75909 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P42568 P50613 P50750 P51946 P51948 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q03111 Q08945 Q13888 Q13889 Q14241 Q15369 Q15370 Q6P1J9 Q6PD62 Q6ZYL4 Q7KZ85 Q8IXH7 Q8IYF1 Q8N7H5 Q8WVC0 Q8WX92 Q92541 Q92759 Q96CJ1 Q96JC9 Q96ST2 Q9GZS3 Q9H3P2 Q9UHB7 Q9Y5B0 Q9Y5B9	AF5Q31 AF9 AFF4 BTF2 BTF2P44 C19orf17 C1orf28 C6orf175 CAK CAK1 CAP35 CCNH CCNK CCNT1 CCNT2 CDC2L4 CDC73 CDK7 CDK9 CDKN7 COBRA1 CPR4 CTDP1 CTR9 EAF1 EAF2 ELL ELOA ELOA2 ELOB ELOC ENL ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HRPT2 IWS1 IWS1L KIAA0155 KIAA0162 KIAA0252 KIAA1182 LEO1 LTG19 MAT1 MCEF MLLT1 MLLT3 MNAT1 MO15 NELFA NELFB NELFCD NELFD NELFE PAF1 PD2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RDL RNF66 RPB7 RTF1 SH2BP1 SKIC8 SPT4H SPT5 SPT5H SPT6H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H SUPT6H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TRAITS TTDA WDR61 WHSC2 XPB XPBC XPD XPDC YEATS1 YEATS3	Homo sapiens (human)
Integrin cell surface interactions	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Basigin CD44 antigen Cadherin-1 Cartilage oligomeric matrix protein Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XXIII) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-4(IV) chain Fibrillin-1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Integrin alpha-10 Integrin alpha-11 Integrin alpha-1 Integrin alpha-2 Integrin alpha-3 Integrin alpha-4 Integrin alpha-5 Integrin alpha-6 Integrin alpha-7 Integrin alpha-8 Integrin alpha-9 Integrin alpha-D Integrin alpha-E Integrin alpha-IIb Integrin alpha-L Integrin alpha-M Integrin alpha-V Integrin alpha-X Integrin beta-1 Integrin beta-2 Integrin beta-3 Integrin beta-5 Integrin beta-6 Integrin beta-7 Integrin beta-8 Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 2 Intercellular adhesion molecule 3 Intercellular adhesion molecule 4 Intercellular adhesion molecule 5 Junctional adhesion molecule A Junctional adhesion molecule B Junctional adhesion molecule C Leukocyte surface antigen CD47 Lumican Osteopontin Platelet endothelial cell adhesion molecule Tenascin Thrombospondin-1 Vascular cell adhesion protein 1 Vascular endothelial growth factor receptor 2 Vitronectin	O00468 O75578 P02462 P02671 P02675 P02679 P02751 P04004 P05106 P05107 P05362 P05556 P06756 P07996 P08514 P08572 P08648 P10451 P11215 P12830 P13598 P13612 P16070 P16284 P17301 P18084 P18564 P19320 P20701 P20702 P20849 P21815 P23229 P24821 P26006 P26010 P26012 P32942 P35555 P35613 P35968 P38570 P39060 P49747 P51884 P53420 P53708 P56199 P57087 P98160 Q01955 Q07092 Q08722 Q13349 Q13683 Q13797 Q14050 Q14055 Q14773 Q5TAT6 Q86Y22 Q9BX67 Q9UKX5 Q9UMF0 Q9Y624	AGRIN AGRN BNSP BSG C21orf43 CD11A CD11B CD11C CD18 CD44 CD47 CD49B CD49D CDH1 CDHE COL13A1 COL16A1 COL18A1 COL23A1 COL4A1 COL4A2 COL4A3 COL4A4 COL9A1 COL9A2 COL9A3 COMP CR3A F11R FBN FBN1 FGA FGB FGG FLK1 FN FN1 FNRA FNRB GP2B GP3A HSPG2 HXB IBSP ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAB ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM1 JAM2 JAM3 JCAM KDR LDC LHR LUM LW MDF2 MDU2 MDU3 MER6 MFI7 MIC4 MSK12 MSK18 MSK8 OPN PECAM1 SLRR2D SPP1 THBS1 TLCN TLN TNC TSP TSP1 UVO VCAM1 VEGFR2 VEJAM VNRA VTN VTNR	Homo sapiens (human)
RHO GTPases activate KTN1	Cell division control protein 42 homolog Kinectin Kinesin heavy chain isoform 5A Kinesin light chain 1 Kinesin light chain 2 Kinesin light chain 3 Kinesin light chain 4 Kinesin-1 heavy chain Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoG Transforming protein RhoA	P33176 P60953 P61586 P63000 P84095 Q07866 Q12840 Q6P597 Q86UP2 Q9H0B6 Q9NSK0	ARH12 ARHA ARHG CDC42 CG1 KIAA0004 KIF5A KIF5B KLC KLC1 KLC2 KLC2L KLC3 KLC4 KNS KNS1 KNS2 KNSL8 KTN1 NKHC1 RAC1 RHO12 RHOA RHOG TC25	Homo sapiens (human)
Regulation of NPAS4 mRNA translation	Helicase MOV-10 Neuronal PAS domain-containing protein 4 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	Q8IUM7 Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 BHLHE79 CAGH26 EIF2C1 EIF2C2 EIF2C3 EIF2C4 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MOV10 NPAS4 NXF PASD10 TNRC6 TNRC6A TNRC6B TNRC6C	Homo sapiens (human)
Neurotransmitter receptors and postsynaptic signal transmission	5-hydroxytryptamine receptor 3A 5-hydroxytryptamine receptor 3B 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3D 5-hydroxytryptamine receptor 3E Glycine receptor subunit alpha-1 Glycine receptor subunit alpha-2 Glycine receptor subunit alpha-3 Glycine receptor subunit beta Neurobeachin	A5X5Y0 O75311 O95264 P23415 P23416 P46098 P48167 Q70Z44 Q8NFP9 Q8WXA8	5HT3R BCL8B GLRA1 GLRA2 GLRA3 GLRB HTR3 HTR3A HTR3B HTR3C HTR3D HTR3E KIAA1544 LYST2 NBEA	Homo sapiens (human)
Formation of the HIV-1 Early Elongation Complex	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 P13984 P18074 P18615 P19387 P19388 P19447 P24928 P30876 P32780 P35269 P36954 P50613 P51946 P51948 P52298 P52434 P52435 P53803 P61218 P62487 P62875 P63272 Q09161 Q13888 Q13889 Q6ZYL4 Q8IXH7 Q8WX92 Q92759 Q9H3P2 Q9Y5B0	BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCNH CDK7 CDKN7 COBRA1 CTDP1 ERCC2 ERCC3 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA1182 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H STK1 SUPT4H SUPT4H1 SUPT5H TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC	Homo sapiens (human)
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	Apoptosis regulator Bcl-2 BH3-interacting domain death agonist Bcl-2-binding component 3, isoforms 1/2 Bcl-2-like protein 11 Bcl-2-like protein 1 Bcl-2-modifying factor Bcl2-associated agonist of cell death Phorbol-12-myristate-13-acetate-induced protein 1 Signal transducer and activator of transcription 3	O43521 P10415 P40763 P55957 Q07817 Q13794 Q92934 Q96LC9 Q9BXH1	APRF BAD BBC3 BBC6 BCL2 BCL2L BCL2L1 BCL2L11 BCL2L8 BCLX BID BIM BMF NOXA PMAIP1 PUMA STAT3	Homo sapiens (human)
tRNA modification in the mitochondrion	3-hydroxyacyl-CoA dehydrogenase type-2 Mitochondrial ribonuclease P catalytic subunit Mitochondrial tRNA-specific 2-thiouridylase 1 Protein MTO1 homolog, mitochondrial tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial tRNA dimethylallyltransferase tRNA methyltransferase 10 homolog C tRNA modification GTPase GTPBP3, mitochondrial	O15091 O75648 Q7L0Y3 Q969Y2 Q99714 Q9BVS5 Q9H3H1 Q9Y2Z2	ERAB GTPBP3 HADH2 HSD17B10 IPT KIAA0391 MOD5 MRPP1 MRPP2 MRPP3 MTGP1 MTO1 MTU1 PRORP RG9MTD1 SCHAD SDR5C1 TRIT1 TRMT1 TRMT10C TRMT61B TRMU XH98G2	Homo sapiens (human)
Pyruvate metabolism	Alanine aminotransferase 1 L-lactate dehydrogenase A chain L-lactate dehydrogenase A-like 6A L-lactate dehydrogenase A-like 6B L-lactate dehydrogenase B chain L-lactate dehydrogenase C chain Lactoylglutathione lyase Mitochondrial pyruvate carrier 1-like protein Mitochondrial pyruvate carrier 1 Mitochondrial pyruvate carrier 2 NAD-dependent malic enzyme, mitochondrial NADP-dependent malic enzyme, mitochondrial NADP-dependent malic enzyme Non-selective voltage-gated ion channel VDAC1 Oxaloacetate tautomerase FAHD1, mitochondrial Pyruvate carboxylase, mitochondrial	O95563 P00338 P07195 P07864 P0DKB6 P11498 P21796 P23368 P24298 P48163 Q04760 Q16798 Q6P587 Q6ZMR3 Q9BYZ2 Q9Y5U8	AAT1 BRP44 BRP44L C16orf36 FAHD1 GLO1 GPT GPT1 LDH3 LDHA LDHAL6 LDHAL6A LDHAL6B LDHB LDHC LDHL LDHL2 LDHX ME1 ME2 ME3 MPC1 MPC1L MPC2 PC VDAC VDAC1 YISKL	Homo sapiens (human)
Zygotic genome activation (ZGA)	CREB-binding protein Cellular tumor antigen p53 Developmental pluripotency-associated protein 2 Developmental pluripotency-associated protein 4 Double homeobox protein 4 Double homeobox protein A Double homeobox protein B Histone acetyltransferase p300 Lysine-specific demethylase 4E Paired-like homeodomain transcription factor LEUTX Terminal uridylyltransferase 4 Terminal uridylyltransferase 7 Tetra-peptide repeat homeobox protein 1 Tetra-peptide repeat homeobox-like protein Tetrapeptide repeat homeobox protein 2 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-3 Zinc finger and SCAN domain-containing protein 4	A0A1W2PPF3 A6NLW8 A8MZ59 B2RXH2 P04637 P0DV77 P46937 Q09472 Q15561 Q17RH7 Q5TAX3 Q5VYS8 Q7L190 Q7Z7J5 Q8N7U7 Q8NAM6 Q92793 Q9UBX2	CBP CREBBP DPPA2 DPPA4 DUX10 DUX4 DUXA DUXB EP300 HS2 KDM4DL KDM4E KIAA0191 KIAA1711 LEUTX P300 P53 PESCRG1 RTEF1 TCF13L1 TEAD4 TEF3 TP53 TPRX1 TPRX2 TPRXL TUT4 TUT7 YAP1 YAP65 ZCCHC11 ZCCHC6 ZNF494 ZSCAN4	Homo sapiens (human)
Metal ion SLC transporters	Calcium/manganese antiporter SLC30A10 Ceruloplasmin Ferroportin Hephaestin High affinity copper uptake protein 1 Natural resistance-associated macrophage protein 1 Natural resistance-associated macrophage protein 2 Solute carrier family 41 member 1 Solute carrier family 41 member 2	O15431 P00450 P49279 P49281 Q6XR72 Q8IVJ1 Q96JW4 Q9BQS7 Q9NP59	COPT1 CP CTR1 DCT1 DMT1 FPN FPN1 HEPH IREG1 KIAA0698 LSH NRAMP NRAMP1 NRAMP2 SLC11A1 SLC11A2 SLC11A3 SLC30A10 SLC31A1 SLC40A1 SLC41A1 SLC41A2 ZNT10 ZNT8	Homo sapiens (human)
mRNA 3'-end processing	ATP-dependent RNA helicase DDX39A Chromatin target of PRMT1 protein Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 Eukaryotic initiation factor 4A-III Leucine zipper protein 4 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Polyadenylate-binding protein 2 Polymerase delta-interacting protein 3 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Pre-mRNA-processing factor 17 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor SLU7 Protein CASC3 Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SAP domain-containing ribonucleoprotein Serine/arginine repetitive matrix protein 1 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 9 Spliceosome RNA helicase DDX39B Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Symplekin THO complex subunit 1 THO complex subunit 2 THO complex subunit 3 THO complex subunit 4 THO complex subunit 5 THO complex subunit 6 THO complex subunit 7 UAP56-interacting factor Zinc finger CCCH domain-containing protein 11A pre-mRNA 3' end processing protein WDR33	O00148 O15234 O43809 O60508 O75152 O94913 O95391 O95639 P26368 P33240 P38919 P51003 P52298 P61326 P82979 P84103 Q01081 Q01130 Q05048 Q05519 Q07955 Q08170 Q09161 Q10570 Q12996 Q13242 Q13243 Q13247 Q13769 Q13838 Q15287 Q16629 Q6I9Y2 Q6UN15 Q86U42 Q86V81 Q86W42 Q8IYB3 Q8N684 Q8NI27 Q8WU68 Q92620 Q92797 Q92989 Q96A72 Q96FV9 Q96J01 Q96QD9 Q9BY77 Q9BZI7 Q9C0J8 Q9H0L4 Q9P127 Q9P2I0 Q9UKF6 Q9Y3Y2 Q9Y5S9	ALY ALYREF ASF BAT1 BEF C1orf77 C22orf19 CASC3 CBP20 CBP80 CDC40 CFIM25 CHTOP CLP1 CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 CXorf3 DDX38 DDX39 DDX39A DDX39B DDX48 DHX38 EHB3 EIF4A3 FIP1 FIP1L1 FOP FYTTD1 HCC1 HEAB HPR1 HRS KIAA0111 KIAA0224 KIAA0663 KIAA0689 KIAA0824 KIAA0983 KIAA1367 KIAA1649 LDC2 LUZP4 MAGOH MAGOH2 MAGOHA MAGOHB MLN51 NAR NCBP NCBP1 NCBP2 NEB1 NIF3L1BP1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PCF11 PDIP46 POLDIP3 PRP16 PRP17 PRPF17 RBM8 RBM8A RENT3B RHE RNPS1 SARNP SF2 SF2P33 SFRS1 SFRS11 SFRS2 SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SLU7 SPK SRM160 SRP20 SRP30C SRP40 SRP55 SRP75 SRRM1 SRSF1 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF9 SYMPK THOC1 THOC2 THOC3 THOC4 THOC5 THOC6 THOC7 U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP UAP56 UIF UPF3B UPF3X WDC146 WDR33 WDR58 ZC3H11A ZC3HDC11A	Homo sapiens (human)
HSF1-dependent transactivation	Alpha-crystallin B chain Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma DnaJ homolog subfamily B member 1 Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock factor protein 1 Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock protein beta-8 Proline-rich AKT1 substrate 1 Regulatory-associated protein of mTOR Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8	O75506 P02511 P07900 P08238 P0DMV8 P0DMV9 P11142 P25685 P34931 P42345 Q00613 Q13554 Q13555 Q13557 Q8N122 Q96B36 Q9BVC4 Q9UJY1 Q9UQM7	AKT1S1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CRYA2 CRYAB CRYAC DNAJ1 DNAJB1 E2IG1 FRAP FRAP1 FRAP2 GBL HDJ1 HSBP1 HSC70 HSF1 HSF1BP HSP22 HSP72 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA8 HSPB5 HSPB8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB HSPF1 HSTF1 HSX70 KIAA0968 KIAA1303 LST8 MLST8 MTOR PRAS40 RAFT1 RAPT1 RAPTOR RPTOR	Homo sapiens (human)
Translesion synthesis by POLI	DNA polymerase iota DNA polymerase zeta catalytic subunit DNA repair protein REV1 Mitotic spindle assembly checkpoint protein MAD2B Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60673 P0CG47 P0CG48 P12004 P15927 P27694 P35244 P35249 P35250 P35251 P40937 P40938 P62979 P62987 Q9UBZ9 Q9UI95 Q9UNA4	MAD2B MAD2L2 PCNA POLI POLZ RAD30B REPA1 REPA2 REPA3 REV1 REV1L REV3 REV3L REV7 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
mRNA decay by 3' to 5' exoribonuclease	7-methylguanosine phosphate-specific 5'-nucleotidase Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 HBS1-like protein Superkiller complex protein 2 Superkiller complex protein 3 Superkiller complex protein 8 m7GpppX diphosphatase	Q06265 Q13868 Q15024 Q15477 Q5RKV6 Q6PGP7 Q969T7 Q96B26 Q96C86 Q9GZS3 Q9NPD3 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2 Q9Y450	CML28 CSL4 DCPS DCS1 DDX13 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 HBS1 HBS1L HINT5 KIAA0116 KIAA0372 KIAA1008 KIAA1038 MTR3 NT5C3B NT5C3L OIP2 PMSCL1 RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SKI2W SKI6 SKIC2 SKIC3 SKIC8 SKIV2 SKIV2L TTC37 W WDR61	Homo sapiens (human)
Lysine catabolism	5-phosphohydroxy-L-lysine phospho-lyase Alpha-aminoadipic semialdehyde dehydrogenase Alpha-aminoadipic semialdehyde synthase, mitochondrial Glutaryl-CoA dehydrogenase, mitochondrial Hydroxylysine kinase Ketimine reductase mu-crystallin Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Mitochondrial 2-oxodicarboxylate carrier Peroxisomal sarcosine oxidase	A2RU49 P49419 Q14894 Q8IUZ5 Q8N5Z0 Q92947 Q9BQT8 Q9P0Z9 Q9UDR5	AADAT AASS AGPHD1 AGXT2L2 ALDH7A1 ATQ1 CRYM GCDH HYKK KAT2 KYAT2 LPIPOX ODC PHYKPL PIPOX PSO SLC25A21 THBP	Homo sapiens (human)
Apoptotic cleavage of cell adhesion proteins	Cadherin-1 Caspase-3 Catenin beta-1 Desmoglein-1 Desmoglein-2 Desmoglein-3 Desmoplakin Occludin Plakophilin-1 Tight junction protein ZO-1 Tight junction protein ZO-2	P12830 P15924 P32926 P35222 P42574 Q02413 Q07157 Q13835 Q14126 Q16625 Q9UDY2	CASP3 CDH1 CDHE CDHF4 CDHF5 CDHF6 CPP32 CTNNB CTNNB1 DSG1 DSG2 DSG3 DSP OCLN PKP1 TJP1 TJP2 UVO X104 ZO1 ZO2	Homo sapiens (human)
Biosynthesis of protectins	Cytochrome P450 1A1 Cytochrome P450 1A2 Leukotriene A-4 hydrolase Polyunsaturated fatty acid lipoxygenase ALOX15	P04798 P05177 P09960 P16050	ALOX15 CYP1A1 CYP1A2 LOG15 LTA4 LTA4H	Homo sapiens (human)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Cathepsin L2 Core-binding factor subunit beta Procathepsin L Runt-related transcription factor 1 Serpin B13 Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 4	O14543 O60911 P07711 P43235 Q01196 Q13951 Q8WXH5 Q9UIV8	AML1 CATL2 CBFA2 CBFB CIS3 CTSK CTSL CTSL1 CTSL2 CTSO CTSO2 CTSU CTSV PI13 RUNX1 SERPINB13 SOCS3 SOCS4 SOCS7 SSI3	Homo sapiens (human)
Negative regulation of FLT3	E3 ubiquitin-protein ligase CBL Fms-related tyrosine kinase 3 ligand Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein kinase FLT3 Receptor-type tyrosine-protein phosphatase eta SH2B adapter protein 3 Src-like-adapter 2 Src-like-adapter Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 6 Tyrosine-protein kinase ABL2 Tyrosine-protein kinase CSK Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14508 O14544 P0CG47 P0CG48 P22681 P36888 P41240 P42684 P49771 P62979 P62987 Q12913 Q13239 Q9H6Q3 Q9UQQ2	ABL2 ABLL ARG C20orf156 CBL CBL2 CD135 CIS2 CIS4 CSK DEP1 FLK2 FLT3 FLT3LG LNK PTPRJ RNF55 RPS27A SH2B3 SLA SLA2 SLAP SLAP1 SLAP2 SOCS2 SOCS4 SOCS6 SSI2 STATI2 STK1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Metabolism of polyamines	Ornithine decarboxylase S-adenosylmethionine decarboxylase proenzyme Spermidine synthase Spermine synthase	P11926 P17707 P19623 P52788	AMD AMD1 ODC1 SMS SPS1 SRM SRML1	Homo sapiens (human)
Resolution of AP sites via the single-nucleotide replacement pathway	DNA ligase 3 DNA polymerase beta DNA repair protein XRCC1	P06746 P18887 P49916	LIG3 POLB XRCC1	Homo sapiens (human)

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