GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1851 - 1875** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Drug resistance in ERBB2 TMD/JMD mutants	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Regulation of PTEN localization	E3 ubiquitin-protein ligase NEDD4 E3 ubiquitin-protein ligase XIAP Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Polyubiquitin-B Polyubiquitin-C Protein PML Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P29590 P46934 P60484 P62979 P62987 P98170 Q93009	API3 BIRC4 HAUSP IAP3 KIAA0093 MMAC1 MYL NEDD4 NEDD4-1 PML PP8675 PTEN RNF71 RPF1 RPS27A TEP1 TRIM19 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 XIAP	Homo sapiens (human)
ADP signalling through P2Y purinoceptor 12	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 P2Y purinoceptor 12	A8MTJ3 O14610 O14775 O60262 P04899 P08754 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63096 P63211 P63215 P63218 Q9H244 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	GNAI1 GNAI2 GNAI2B GNAI3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 HORK3 P2RY12	Homo sapiens (human)
Chylomicron clearance	Apolipoprotein B-100 Apolipoprotein E Hepatic triacylglycerol lipase Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor	P01130 P02649 P04114 P11150 Q5SW96	APOB APOE ARH HTGL LDLR LDLRAP1 LIPC	Homo sapiens (human)
Loss of MECP2 binding ability to 5mC-DNA	Histone deacetylase 1 Paired amphipathic helix protein Sin3a	Q13547 Q96ST3	HDAC1 RPD3L1 SIN3A	Homo sapiens (human)
TRAF6 mediated NF-kB activation	Advanced glycosylation end product-specific receptor Amyloid-beta precursor protein Antiviral innate immune response receptor RIG-I E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Mitogen-activated protein kinase kinase kinase 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor-interacting Ras-like protein 1 NF-kappa-B inhibitor-interacting Ras-like protein 2 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Protein S100-A12 Protein S100-B Serum amyloid A-1 protein TNF receptor-associated factor 2 TNF receptor-associated factor 6 Transcription factor p65	O14920 O15111 O95786 P04271 P05067 P09429 P0DJI8 P19838 P25963 P80511 Q00653 Q04206 Q12933 Q13233 Q14258 Q15109 Q15653 Q7Z434 Q8IUD6 Q9BYX4 Q9C037 Q9NYR9 Q9NYS0 Q9Y4K3 Q9Y6K9	A4 AD1 AGER APP CHUK DDX58 EFP FIP3 HMG1 HMGB1 IFIH1 IKBA IKBB IKBKB IKBKG IKKA IKKB IPS1 KBRAS1 KBRAS2 KIAA1271 LYT10 MAD3 MAP3K1 MAPKKK1 MAVS MDA5 MEKK MEKK1 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA NFKBIB NKIRAS1 NKIRAS2 RAGE RELA RH116 RIGI RNF135 RNF147 RNF85 RNF87 S100A12 S100B SAA1 TCF16 TRAF2 TRAF6 TRAP3 TRIM25 TRIM4 TRIP9 VISA ZNF147	Homo sapiens (human)
Amino acid transport across the plasma membrane	Amino acid transporter heavy chain SLC3A1 Amino acid transporter heavy chain SLC3A2 Asc-type amino acid transporter 1 Cationic amino acid transporter 3 Cystine/glutamate transporter High affinity cationic amino acid transporter 1 Inactive sodium-dependent neutral amino acid transporter B(0)AT3 Large neutral amino acids transporter small subunit 1 Large neutral amino acids transporter small subunit 2 Large neutral amino acids transporter small subunit 3 Large neutral amino acids transporter small subunit 4 Mitochondrial basic amino acids transporter Monocarboxylate transporter 10 Neutral amino acid transporter A Neutral amino acid transporter B(0) Neutral amino acid uniporter 4 Proton-coupled amino acid transporter 1 Proton-coupled amino acid transporter 2 Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) Sodium- and chloride-dependent taurine transporter Sodium- and chloride-dependent transporter XTRP3 Sodium-coupled neutral amino acid symporter 1 Sodium-coupled neutral amino acid symporter 2 Sodium-coupled neutral amino acid transporter 3 Sodium-coupled neutral amino acid transporter 4 Sodium-coupled neutral amino acid transporter 5 Sodium-dependent neutral amino acid transporter B(0)AT1 Sodium-dependent neutral amino acid transporter B(0)AT2 Y+L amino acid transporter 1 Y+L amino acid transporter 2 b(0,+)-type amino acid transporter 1	O75387 P08195 P30825 P31641 P43007 P48065 P82251 Q01650 Q07837 Q15758 Q495M3 Q695T7 Q6YBV0 Q7Z2H8 Q8N370 Q8N8R3 Q8TF71 Q8WUX1 Q8WY07 Q92536 Q969I6 Q96N87 Q96QD8 Q99624 Q9H2H9 Q9H2J7 Q9NP91 Q9NS82 Q9UHI5 Q9UM01 Q9UN76 Q9UPY5	ASC1 ASCT1 ASCT2 ATA1 ATA2 ATA3 ATRC1 ATRC3 B0AT1 B0AT2 B0AT3 BAT1 BGT1 C14orf69 CAT3 CD98LC ERR G17 JM24 KIAA0245 KIAA1382 LAT1 LAT2 LAT3 LAT4 M7V1 MCT10 MDU1 MPE16 NAT1 NAT2 NAT3 NBAT NTT73 ORNT3 PAT1 PAT2 PAT4 PB39 POV1 RDR RDRC REC1L SAT1 SAT2 SATT SBAT1 SIT1 SLC16A10 SLC1A4 SLC1A5 SLC25A29 SLC36A1 SLC36A2 SLC36A4 SLC38A1 SLC38A2 SLC38A3 SLC38A4 SLC38A5 SLC3A1 SLC3A2 SLC43A1 SLC43A2 SLC6A12 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A20 SLC6A6 SLC7A1 SLC7A10 SLC7A11 SLC7A3 SLC7A5 SLC7A6 SLC7A7 SLC7A8 SLC7A9 SN1 SN2 SNAT1 SNAT2 SNAT3 SNAT4 SNAT5 TAT1 TRAMD1 XT3 XTRP2 XTRP3	Homo sapiens (human)
Activation of gene expression by SREBF (SREBP)	3'-5' exoribonuclease HELZ2 7-dehydrocholesterol reductase Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 Delta(14)-sterol reductase TM7SF2 Diphosphomevalonate decarboxylase F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Farnesyl pyrophosphate synthase Fatty acid synthase Geranylgeranyl pyrophosphate synthase Glycerol-3-phosphate acyltransferase 1, mitochondrial Histone-arginine methyltransferase CARM1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Lanosterol 14-alpha demethylase Lanosterol synthase Lathosterol oxidase Mediator of RNA polymerase II transcription subunit 1 Metal regulatory transcription factor 1 Mevalonate kinase Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Peroxisome proliferator-activated receptor alpha Phosphomevalonate kinase Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Squalene monooxygenase Squalene synthase Stearoyl-CoA desaturase Sterol regulatory element-binding protein 2 Transcription factor Sp1 Trimethylguanosine synthase Very long chain fatty acid elongase 6	O00763 O00767 O60907 O75845 O76062 O95749 P08047 P14324 P19793 P23511 P25208 P37268 P48449 P49327 P53602 Q01581 Q03426 Q07869 Q12772 Q13085 Q13907 Q13952 Q14534 Q14686 Q14872 Q15126 Q15596 Q15648 Q15788 Q16850 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q9BYK8 Q9BZK7 Q9H5J4 Q9HCL2 Q9UBM7	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB AIB3 ANG1 ARC205 BAF60C BHLHD2 BHLHE74 BHLHE75 CARM1 CBP CHD9 CREBBP CRSP1 CRSP200 CYP51 CYP51A1 D7SR DHCR7 DRIP205 DRIP230 ELOVL6 ERG1 FACE FADS5 FAS FASN FDFT1 FDPS FPS GGPS1 GPAM GPAT1 HAP3 HCA137 HELZ2 HMGCS HMGCS1 IDI1 IRA1 KIAA0181 KIAA0308 KIAA1293 KIAA1560 KIAA1769 KISH2 LCE LSS MED1 MPD MTF1 MVD MVK NCOA1 NCOA2 NCOA6 NCOA6IP NFYA NFYB NFYC NR1C1 NR2B1 OSC PBP PIMT PMKI PMVK PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SC5D SC5DL SCD SCD1 SCDOS SMARCD3 SP1 SQLE SRC1 SRC2 SREBF2 SREBP2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TM7SF2 TRAP220 TRBP TRIP2 TSFP1	Homo sapiens (human)
Nuclear import of Rev protein	Aladin E3 SUMO-protein ligase RanBP2 GTP-binding nuclear protein Ran Importin subunit beta-1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleophosmin Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog Regulator of chromosome condensation mRNA export factor RAE1	A8CG34 O15504 O75694 P06748 P12270 P18754 P35658 P37198 P49790 P49792 P55735 P57740 P62826 P78406 Q12769 Q14974 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA ARA24 C7orf14 CAIN CAN CG1 CHC1 D3S1231E KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KPNB1 MP44 MRNP41 NDC1 NPAP60L NPM NPM1 NTF97 NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C RAE1 RAN RANBP2 RCC1 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR	Homo sapiens (human)
Synthesis and processing of ENV and VPU	Envelope glycoprotein gp160 Furin Protein Vpu	P04578 P05919 P09958	FUR FURIN PACE PCSK3 env vpu	Homo sapiens (human)
Metabolism of serotonin	Aldehyde dehydrogenase, mitochondrial Amine oxidase [flavin-containing] A	P05091 P21397	ALDH2 ALDM MAOA	Homo sapiens (human)
Mitochondrial calcium ion transport	A-kinase anchor protein 1, mitochondrial Calcium uniporter protein, mitochondrial Calcium uniporter regulatory subunit MCUb, mitochondrial Calcium uptake protein 1, mitochondrial Calcium uptake protein 2, mitochondrial Calcium uptake protein 3, mitochondrial Essential MCU regulator, mitochondrial Mitochondrial proton/calcium exchanger protein Mitochondrial sodium/calcium exchanger protein Non-selective voltage-gated ion channel VDAC1 Sodium/calcium exchanger 3 Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3	O95202 P21796 P45880 P57103 Q6J4K2 Q86XE3 Q8IYU8 Q8NE86 Q92667 Q9BPX6 Q9H4I9 Q9NWR8 Q9Y277	AKAP1 AKAP149 C10orf42 C22orf32 CALC CBARA1 CCDC109A CCDC109B EFHA1 EFHA2 EMRE LETM1 MCU MCUB MICU1 MICU2 MICU3 NCKX6 NCLX NCX3 PRKA1 SLC24A6 SLC8A3 SLC8B1 SMDT1 VDAC VDAC1 VDAC2 VDAC3	Homo sapiens (human)
Biosynthesis of DPAn-3 SPMs	Prostaglandin G/H synthase 2	P35354	COX2 PTGS2	Homo sapiens (human)
Cytosolic tRNA aminoacylation	Alanine--tRNA ligase, cytoplasmic Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Arginine--tRNA ligase, cytoplasmic Asparagine--tRNA ligase, cytoplasmic Aspartate--tRNA ligase, cytoplasmic Bifunctional glutamate/proline--tRNA ligase Cysteine--tRNA ligase, cytoplasmic Eukaryotic translation elongation factor 1 epsilon-1 Glutamine--tRNA ligase Glycine--tRNA ligase Histidine--tRNA ligase, cytoplasmic Inorganic pyrophosphatase Isoleucine--tRNA ligase, cytoplasmic Leucine--tRNA ligase, cytoplasmic Lysine--tRNA ligase Methionine--tRNA ligase, cytoplasmic Phenylalanine--tRNA ligase alpha subunit Phenylalanine--tRNA ligase beta subunit Serine--tRNA ligase, cytoplasmic Threonine--tRNA ligase 1, cytoplasmic Tryptophan--tRNA ligase, cytoplasmic Tyrosine--tRNA ligase, cytoplasmic Valine--tRNA ligase	O43324 O43776 P07814 P12081 P14868 P23381 P26639 P26640 P41250 P41252 P47897 P49588 P49589 P49591 P54136 P54577 P56192 Q12904 Q13155 Q15046 Q15181 Q9NSD9 Q9P2J5 Q9Y285	AARS AARS1 AIMP1 AIMP2 AIMP3 CARS CARS1 DARS DARS1 EEF1E1 EMAP2 EPRS EPRS1 FARS FARSA FARSB FARSL FARSLA FARSLB FRSB G7A GARS GARS1 GLNS HARS HARS1 HRS IARS IARS1 IFI53 IOPPP JTV1 KARS KARS1 KIAA0070 KIAA1352 LARS LARS1 MARS MARS1 NARS NARS1 NRS P18 PARS PP PPA1 QARS QARS1 QPRS RARS RARS1 SARS SARS1 SCYE1 SERS TARS TARS1 VARS VARS1 VARS2 WARS WARS1 WRS YARS YARS1	Homo sapiens (human)
SUMO is proteolytically processed	Sentrin-specific protease 1 Sentrin-specific protease 2 Sentrin-specific protease 5 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 Q96HI0 Q9HC62 Q9P0U3	KIAA1331 SENP1 SENP2 SENP5 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUMO1 SUMO2 SUMO3 UBL1	Homo sapiens (human)
Defective ABCB11 causes PFIC2 and BRIC2	Bile salt export pump	O95342	ABCB11 BSEP	Homo sapiens (human)
Defective visual phototransduction due to RDH5 loss of function	Retinaldehyde-binding protein 1 Retinol dehydrogenase 5	P12271 Q92781	CRALBP HSD17B9 RDH1 RDH5 RLBP1 SDR9C5	Homo sapiens (human)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Aurora kinase A Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/LRR-repeat protein 18 F-box/LRR-repeat protein 7 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 S-phase kinase-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O14965 O43242 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q13200 Q13616 Q15008 Q16186 Q96ME1 Q99436 Q99460 Q9UJT9 Q9UNM6	ADRM1 AIK AIRK1 ARK1 AURA AURKA AYK1 BTAK C7orf76 CUL1 DSS1 EMC19 FBL18 FBL6 FBL7 FBXL18 FBXL7 GP110 HC2 HC3 HC8 HC9 HSPC IAK1 KIAA0107 KIAA0840 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBX1 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A STK15 STK6 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)
APC-Cdc20 mediated degradation of Nek2A	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase Nek2 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 O43684 O60566 P0CG47 P0CG48 P30260 P51668 P51955 P51965 P60006 P62979 P62987 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L NEK2 NEK2A NLK1 RPS27A SFT SSK1 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
NFE2L2 regulating tumorigenic genes	Amphiregulin Apoptosis regulator Bcl-2 Bcl-2-like protein 1 CREB-binding protein Histone acetyltransferase p300 Neurogenic locus notch homolog protein 1 Nuclear factor erythroid 2-related factor 2 Platelet-derived growth factor subunit A Pro-epidermal growth factor Transcription factor MafK Transcription factor Sp1	O60675 P01133 P04085 P08047 P10415 P15514 P46531 Q07817 Q09472 Q16236 Q92793	AREG AREGB BCL2 BCL2L BCL2L1 BCLX CBP CREBBP EGF EP300 MAFK NFE2L2 NOTCH1 NRF2 P300 PDGF1 PDGFA SDGF SP1 TAN1 TSFP1	Homo sapiens (human)
Activation of RAC1 downstream of NMDARs	ARF GTPase-activating protein GIT1 Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type 1 Calmodulin-1 Ras-related C3 botulinum toxin substrate 1	P0DP23 P63000 Q14012 Q8N5S9 Q96RR4 Q9Y2X7	CALM CALM1 CAM CAM1 CAMK1 CAMKK1 CAMKK2 CAMKKA CAMKKB GIT1 KIAA0787 RAC1 TC25	Homo sapiens (human)
Trafficking of GluR2-containing AMPA receptors	AP-2 complex subunit alpha-1 Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor 3 Glutamate receptor 4 Glutamate receptor-interacting protein 1 Glutamate receptor-interacting protein 2 PRKCA-binding protein Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type Tetraspanin-7 Vesicle-fusing ATPase	O95782 P05129 P05771 P17252 P41732 P42261 P42262 P42263 P46459 P48058 Q9C0E4 Q9NRD5 Q9Y3R0	A15 ADTAA AP2A1 CLAPA1 DXS1692E GLUA1 GLUH1 GLUR1 GLUR2 GLUR3 GLUR4 GLURC GRIA1 GRIA2 GRIA3 GRIA4 GRIP1 GRIP2 GluA2 GluA3 GluA4 KIAA1719 MXS1 NSF PICK1 PKCA PKCB PKCG PRKACA PRKCA PRKCABP PRKCB PRKCB1 PRKCG TM4SF2 TSPAN7	Homo sapiens (human)
EGR2 and SOX10-mediated initiation of Schwann cell myelination	3-hydroxy-3-methylglutaryl-coenzyme A reductase Adhesion G-protein coupled receptor G6 Adhesion G-protein coupled receptor V1 Dystroglycan 1 Dystrophin-related protein 2 E3 SUMO-protein ligase EGR2 Histone deacetylase 2 Laminin subunit alpha-2 Laminin subunit beta-1 Laminin subunit gamma-1 Lanosterol 14-alpha demethylase Myelin basic protein Myelin protein P0 Myelin-associated glycoprotein NGFI-A-binding protein 1 NGFI-A-binding protein 2 POU domain, class 3, transcription factor 1 POU domain, class 3, transcription factor 2 Periaxin Peripheral myelin protein 22 Stearoyl-CoA desaturase 5 Sterol regulatory element-binding protein 2 Transcription activator BRG1 Transcription factor SOX-10 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-1 Utrophin WW domain-containing transcription regulator protein 1	P02686 P04035 P07942 P11047 P11161 P20265 P20916 P24043 P25189 P28347 P46937 P46939 P51532 P56693 Q01453 Q03052 Q12772 Q13474 Q13506 Q14118 Q15742 Q16850 Q86SK9 Q86SQ4 Q8WXG9 Q92769 Q9BXM0 Q9GZV5	ACOD4 ADGRG6 ADGRV1 BAF190A BHLHD2 BRG1 BRN2 CYP51 CYP51A1 DAG1 DMDL DREG DRP1 DRP2 EGR2 GAS3 GMA GPR126 GPR98 HDAC2 HMGCR KIAA0686 KIAA1620 KIAA1943 KROX20 LAMA2 LAMB1 LAMB2 LAMC1 LAMM MADER MAG MASS1 MBP MPZ NAB1 NAB2 OCT6 OCT7 OTF6 OTF7 PMP22 POU3F1 POU3F2 PRX SCD2 SCD4 SCD5 SMARCA4 SNF2B SNF2L4 SOX10 SREBF2 SREBP2 TAZ TCF13 TEAD1 TEF1 UTRN VIGR VLGR1 WWTR1 YAP1 YAP65	Homo sapiens (human)
LDL clearance	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Apolipoprotein B-100 Carboxylesterase 3 Clathrin heavy chain 1 Clathrin light chain A Lipolysis-stimulated lipoprotein receptor Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor Lysosomal acid lipase/cholesteryl ester hydrolase NPC intracellular cholesterol transporter 1 NPC intracellular cholesterol transporter 2 Neutral cholesterol ester hydrolase 1 Proprotein convertase subtilisin/kexin type 9 Sterol O-acyltransferase 1 Sterol O-acyltransferase 2	O15118 O75908 O94973 O95782 P01130 P04114 P09496 P35610 P38571 P53680 P61916 P63010 Q00610 Q5SW96 Q6PIU2 Q6UWW8 Q86X29 Q8NBP7 Q96CW1	AADACL1 ACACT ACACT1 ACACT2 ACAT ACAT1 ACAT2 ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB ARH CES3 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 HE1 HIP9 HYPJ ILDR3 KIAA0034 KIAA0109 KIAA0899 KIAA1363 LDLR LDLRAP1 LIPA LISCH LSR NARC1 NCEH1 NPC1 NPC2 PCSK9 SOAT SOAT1 SOAT2 STAT	Homo sapiens (human)
Defective DNA double strand break response due to BARD1 loss of function	BRCA1-associated RING domain protein 1 Breast cancer type 1 susceptibility protein	P38398 Q99728	BARD1 BRCA1 RNF53	Homo sapiens (human)

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