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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cystic fibrosis
Summary
- Synonym
-
- CF
- mucoviscidosis
- Definition
- A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.
- Super Class
- autosomal recessive disease syndrome
External Links
- Disease Ontology
- DOID:1485
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- ORDO
- OMIM
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4586 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | |
| 4842 | NOS1 | nitric oxide synthase 1 | |
| 4843 | NOS2 | nitric oxide synthase 2 | |
| 4846 | NOS3 | nitric oxide synthase 3 | |
| 5243 | ABCB1 | ATP binding cassette subfamily B member 1 | |
| 5244 | ABCB4 | ATP binding cassette subfamily B member 4 | |
| 5465 | PPARA | peroxisome proliferator activated receptor alpha | |
| 5644 | PRSS1 | serine protease 1 | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 | |
| 5806 | PTX3 | pentraxin 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11554 | Adrb1 | adrenergic receptor, beta 1 | |
| 11555 | Adrb2 | adrenergic receptor, beta 2 | |
| 11556 | Adrb3 | adrenergic receptor, beta 3 | |
| 11596 | Ager | advanced glycosylation end product-specific receptor | |
| 12475 | Cd14 | CD14 antigen | |
| 12638 | Cftr | cystic fibrosis transmembrane conductance regulator | |
| 12724 | Clcn2 | chloride channel, voltage-sensitive 2 | |
| 12766 | Cxcr3 | C-X-C motif chemokine receptor 3 | |
| 12986 | Csf3r | colony stimulating factor 3 receptor | |
| 13076 | Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25747 | Ppara | peroxisome proliferator activated receptor alpha | |
| 29199 | Hfe | homeostatic iron regulator | |
| 29260 | Tlr4 | toll-like receptor 4 | |
| 29397 | Ccl11 | C-C motif chemokine ligand 11 | |
| 29527 | Ptgs2 | prostaglandin-endoperoxide synthase 2 | |
| 59086 | Tgfb1 | transforming growth factor, beta 1 | |
| 60350 | Cd14 | CD14 molecule | |
| 60582 | Il1rn | interleukin 1 receptor antagonist | |
| 63868 | Hspd1 | heat shock protein family D (Hsp60) member 1 | |
| 81687 | Mmp9 | matrix metallopeptidase 9 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 34091 | Spn28Dc | Serpin 28Dc | |
| 34714 | Edem2 | ER degradation enhancer, mannosidase alpha-like 2 | |
| 36428 | Mdr49 | Multi drug resistance 49 | |
| 38326 | Pxn | Peroxidasin | |
| 38726 | Mdr65 | Multi drug resistance 65 | |
| 41549 | Octbeta2R | Octopamine beta2 receptor | |
| 42652 | Octbeta1R | Octopamine beta1 receptor | |
| 43222 | Tl | Toll | |
| 47905 | l(2)03659 | lethal (2) 03659 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174821 | clh-1 | CBS domain-containing protein | |
| 177857 | C47E12.3 | alpha-1,2-Mannosidase | |
| 178215 | pgp-1 | Multidrug resistance protein pgp-1 | |
| 179197 | cri-2 | Putative metalloproteinase inhibitor tag-225 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 181101 | mec-10 | Degenerin mec-10 | |
| 181288 | pxn-2 | Peroxidasin homolog pxn-2 | |
| 181326 | pgp-3 | Multidrug resistance protein pgp-3 | |
| 181728 | mec-4 | Degenerin mec-4 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0003251 | Male infertility |
| HP:0001508 | Failure to thrive |
| HP:0012236 | Elevated sweat chloride |
| HP:0002035 | Rectal prolapse |
| HP:0000938 | Osteopenia |
| HP:0002726 | Recurrent Staphylococcus aureus infections |
| HP:0000246 | Sinusitis |
| HP:0002107 | Pneumothorax |
| HP:0002910 | Elevated circulating hepatic transaminase concentration |
| HP:0001394 | Cirrhosis |
