lung disease

Summary
Definition
A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.
Super Class
lower respiratory tract disease
Disease Ontology
DOID:850
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying entries 11 - 16 of 16 in total
Gene ID Gene Symbol Description Source
4353 MPO myeloperoxidase
6440 SFTPC surfactant protein C
6441 SFTPD surfactant protein D
7040 TGFB1 transforming growth factor beta 1
7097 TLR2 toll like receptor 2
653509 SFTPA1 surfactant protein A1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
24310 Ace angiotensin I converting enzyme
25245 Bdkrb2 bradykinin receptor B2
25325 Il10 interleukin 10
25369 Adora2a adenosine A2a receptor
29260 Tlr4 toll-like receptor 4
29290 Adora1 adenosine A1 receptor
81687 Mmp9 matrix metallopeptidase 9

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025