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MIRAGE
acute myeloid leukemia
Summary
- Synonym
-
- AML - acute Myeloid Leukemia
- Leukemia, Myelocytic, acute
- acute myeloblastic leukaemia
- acute myeloblastic leukemia
- acute myelogenous leukaemia
- acute myelogenous leukemia
- acute myeloid leukaemia
- Definition
- A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.
- Super Class
- myeloid leukemia
External Links
- Disease Ontology
- DOID:9119
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- GARD
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 7015 | TERT | telomerase reverse transcriptase | |
| 7157 | TP53 | tumor protein p53 | |
| 7298 | TYMS | thymidylate synthetase | |
| 7422 | VEGFA | vascular endothelial growth factor A | |
| 7852 | CXCR4 | C-X-C motif chemokine receptor 4 | |
| 7980 | TFPI2 | tissue factor pathway inhibitor 2 | |
| 7994 | KAT6A | lysine acetyltransferase 6A | |
| 8021 | NUP214 | nucleoporin 214 | |
| 8028 | MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor | |
| 8233 | ZRSR2 | zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O14746 | Telomerase reverse transcriptase | |
| O15553 | Pyrin | |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | |
| P00519 | Tyrosine-protein kinase ABL1 | |
| P01111 | GTPase NRas | |
| P01116 | GTPase KRas | |
| P01583 | Interleukin-1 alpha | |
| P01920 | HLA class II histocompatibility antigen, DQ beta 1 chain | |
| P04141 | Granulocyte-macrophage colony-stimulating factor | |
| P04179 | Superoxide dismutase [Mn], mitochondrial |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P45481 | Histone lysine acetyltransferase CREBBP | |
| P55200 | Histone-lysine N-methyltransferase 2A | |
| P59598 | Polycomb group protein ASXL1 | |
| Q00342 | Receptor-type tyrosine-protein kinase FLT3 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P49687 | Nucleoporin NUP145 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0004808 | Acute myeloid leukemia |
