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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 181 - 190 of 325 in total
Gene ID Gene Symbol Description Source
5019 OXCT1 3-oxoacid CoA-transferase 1
5054 SERPINE1 serpin family E member 1
5069 PAPPA pappalysin 1
5105 PCK1 phosphoenolpyruvate carboxykinase 1
5122 PCSK1 proprotein convertase subtilisin/kexin type 1
5126 PCSK2 proprotein convertase subtilisin/kexin type 2
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
5176 SERPINF1 serpin family F member 1
5243 ABCB1 ATP binding cassette subfamily B member 1
5286 PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Displaying entries 201 - 210 of 249 in total
Gene ID Gene Symbol Description Source
56637 Gsk3b glycogen synthase kinase 3 beta
56717 Mtor mechanistic target of rapamycin kinase
58805 Mlxipl MLX interacting protein-like
58992 F12 coagulation factor XII (Hageman factor)
59027 Nampt nicotinamide phosphoribosyltransferase
66085 Eif3f eukaryotic translation initiation factor 3, subunit F
68054 Serpina12 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
68916 Cdkal1 CDK5 regulatory subunit associated protein 1-like 1
70839 P2ry12 purinergic receptor P2Y, G-protein coupled 12
71665 Fuca1 fucosidase, alpha-L- 1, tissue
Displaying entries 1 - 10 of 166 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24182 Agtr2 angiotensin II receptor, type 2
24185 Akt1 AKT serine/threonine kinase 1
24192 Akr1b1 aldo-keto reductase family 1 member B1
24221 Avp arginine vasopressin
24225 Bdnf brain-derived neurotrophic factor
24241 Calca calcitonin-related polypeptide alpha
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24310 Ace angiotensin I converting enzyme
Displaying entries 1 - 10 of 80 in total
Gene ID Gene Symbol Description Source
31234 Pdfr Pigment-dispersing factor receptor
31248 sgg shaggy
31271 w white
31806 Ogg1 8-oxoguanine DNA glycosylase
31926 Idgf4 Imaginal disc growth factor 4
32442 Rab3-GEF Rab3 GDP-GTP exchange factor
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33496 lilli lilliputian
34091 Spn28Dc Serpin 28Dc
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
30173 nog3 noggin 3
30174 nog1 noggin 1
30262 ins preproinsulin
30667 mtnr1aa melatonin receptor 1A a
30668 mtnr1bb melatonin receptor 1Bb
30682 vegfaa vascular endothelial growth factor Aa
266751 adra2b adrenoceptor alpha 2B
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
Displaying entries 11 - 20 of 20 in total
Gene ID Gene Symbol Description Source Organism
407879 ppp1cc protein phosphatase 1, catalytic subunit, gamma isozyme Xenopus tropicalis (tropical clawed frog)
432039 pon2.S paraoxonase 2 S homeolog Xenopus laevis (African clawed frog)
432172 akt2.S v-akt murine thymoma viral oncogene homolog 2 S homeolog Xenopus laevis (African clawed frog)
448238 cadm2 cell adhesion molecule 2 Xenopus tropicalis (tropical clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
493191 nog noggin Xenopus tropicalis (tropical clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100489505 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 69 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
171782 abt-2 ABC transporter domain-containing protein
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
172509 gpdh-3 putative glycerol-3-phosphate dehydrogenase, mitochondrial
173297 F49B2.6 Aminopeptidase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175076 ace-3 Carboxylic ester hydrolase
175182 ver-1 Protein ver-1
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
850678 YBT1 bile acid-transporting ATPase YBT1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
2645 GCK glucokinase
6514 SLC2A2 solute carrier family 2 member 2
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024