obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 1 - 10 of 343 in total
Gene ID Gene Symbol Description Source
19 ABCA1 ATP binding cassette subfamily A member 1
32 ACACB acetyl-CoA carboxylase beta
38 ACAT1 acetyl-CoA acetyltransferase 1
51 ACOX1 acyl-CoA oxidase 1
123 PLIN2 perilipin 2
133 ADM adrenomedullin
134 ADORA1 adenosine A1 receptor
154 ADRB2 adrenoceptor beta 2
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
Displaying entries 111 - 120 of 241 in total
Gene ID Gene Symbol Description Source
16956 Lpl lipoprotein lipase
17195 Mbl2 mannose-binding lectin (protein C) 2
17201 Mc3r melanocortin 3 receptor
17202 Mc4r melanocortin 4 receptor
17395 Mmp9 matrix metallopeptidase 9
17762 Mapt microtubule-associated protein tau
17869 Myc myelocytomatosis oncogene
17977 Ncoa1 nuclear receptor coactivator 1
18024 Nfe2l2 nuclear factor, erythroid derived 2, like 2
18127 Nos3 nitric oxide synthase 3, endothelial cell
Displaying entries 1 - 10 of 151 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24217 Atp4b ATPase H+/K+ transporting subunit beta
24225 Bdnf brain-derived neurotrophic factor
24232 C3 complement C3
24267 Comt catechol-O-methyltransferase
24310 Ace angiotensin I converting enzyme
24318 Drd2 dopamine receptor D2
24367 Fgg fibrinogen gamma chain
24377 G6pd glucose-6-phosphate dehydrogenase
Displaying entries 21 - 30 of 43 in total
Gene ID Gene Symbol Description Source
36411 sca scabrous
36849 DAT Dopamine transporter
37028 ACOX1 acyl-CoA oxidase 1
37089 fj four-jointed
37447 Sdc Syndecan
37772 GlyT Glycine transporter
37778 gbb glass bottom boat
38109 Glut1 Glucose transporter 1
38868 Snmp2 Sensory neuron membrane protein 2
39404 INPP5E Inositol polyphosphate 5-phosphatase E
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 51 in total
Gene ID Gene Symbol Description Source
171782 abt-2 ABC transporter domain-containing protein
171994 lin-44 Abnormal cell lineage protein 44
171999 poml-2 Arylesterase
173169 eif-6 Eukaryotic translation initiation factor 6
173399 cwn-1 Protein Wnt-1
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175201 stim-1 Stromal interaction molecule 1
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
Displaying entries 21 - 29 of 29 in total
Gene ID Gene Symbol Description Source
855247 HFA1 acetyl-CoA carboxylase HFA1
855301 TRM732 tRNA methylation protein TRM732
855480 ZWF1 glucose-6-phosphate dehydrogenase
855483 KEX2 kexin KEX2
855949 PEP4 proteinase A
856020 SEC16 Sec16p
856294 RHO1 Rho family GTPase RHO1
856533 ECM14 putative metallocarboxypeptidase
856699 NPP2 nucleotide diphosphatase/phosphodiesterase NPP2
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
9672 SDC3 syndecan 3

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Last updated: December 9, 2024