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Standards Ontologies Notations
heroin dependence

Summary
Definition
An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.
Super Class
opiate dependence
Disease Ontology
DOID:9976
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying entries 21 - 30 of 35 in total
Gene ID Gene Symbol Description Source
2571 GAD1 glutamate decarboxylase 1
2572 GAD2 glutamate decarboxylase 2
2668 GDNF glial cell derived neurotrophic factor
2890 GRIA1 glutamate ionotropic receptor AMPA type subunit 1
2903 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A
2912 GRM2 glutamate metabotropic receptor 2
3359 HTR3A 5-hydroxytryptamine receptor 3A
4803 NGF nerve growth factor
4886 NPY1R neuropeptide Y receptor Y1
4985 OPRD1 opioid receptor delta 1
Displaying entries 1 - 10 of 34 in total
Gene ID Gene Symbol Description Source
11423 Ache acetylcholinesterase
11549 Adra1a adrenergic receptor, alpha 1a
11669 Aldh2 aldehyde dehydrogenase 2, mitochondrial
12038 Bche butyrylcholinesterase
12064 Bdnf brain derived neurotrophic factor
12846 Comt catechol-O-methyltransferase
13095 Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29
13162 Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
13488 Drd1 dopamine receptor D1
13489 Drd2 dopamine receptor D2
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
24225 Bdnf brain-derived neurotrophic factor
24267 Comt catechol-O-methyltransferase
24318 Drd2 dopamine receptor D2
24409 Grin2a glutamate ionotropic receptor NMDA type subunit 2A
24415 Grm2 glutamate metabotropic receptor 2
24613 Oprd1 opioid receptor, delta 1
24898 Slc6a3 solute carrier family 6 member 3
24922 Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3
25085 Th tyrosine hydroxylase
25453 Gdnf glial cell derived neurotrophic factor
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
32554 Lcch3 Ligand-gated chloride channel homolog 3
33007 Dop2R Dopamine 2-like receptor
36428 Mdr49 Multi drug resistance 49
36849 DAT Dopamine transporter
37892 mAChR-A muscarinic Acetylcholine Receptor, A-type
38726 Mdr65 Multi drug resistance 65
38742 GluRIA Glutamate receptor IA
41625 Ace Acetylcholine esterase
41726 Dop1R1 Dopamine 1-like receptor 1
43484 Dop1R2 Dopamine 1-like receptor 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
58133 ngfb nerve growth factor b (beta polypeptide)
114549 ache acetylcholinesterase (Yt blood group)
561372 comta catechol-O-methyltransferase a
565370 comtb catechol-O-methyltransferase b
Displaying all 4 entries
Gene ID Gene Symbol Description Source Organism
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
100127346 grin2a.L glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 11 - 16 of 16 in total
Gene ID Gene Symbol Description Source
181326 pgp-3 Multidrug resistance protein pgp-3
181706 ace-1 Acetylcholinesterase 1
183715 dop-4 Dopamine receptor 4
184572 ser-5 G-protein coupled receptors family 1 profile domain-containing protein
189837 gbb-1 G-protein coupled receptors family 3 profile domain-containing protein;Gamma-aminobutyric acid type B receptor subunit 1
191707 mgl-1 G-protein coupled receptors family 3 profile domain-containing protein;putative metabotropic glutamate receptor mgl-1
Displaying 1 entry
Gene ID Gene Symbol Description Source
853671 STE6 ATP-binding cassette a-factor transporter STE6
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024