FGFR3b ligand binding and activation
|
|
|
- Aigf
- Fgf-1
- Fgf-9
- Fgf1
- Fgf17
- Fgf18
- Fgf20
- Fgf8
- Fgf9
- Fgfa
- Fgfr3
- Mfr3
- Sam3
|
|
FGFRL1 modulation of FGFR1 signaling
|
|
|
- Aigf
- Fgf-2
- Fgf-3
- Fgf-4
- Fgf-5
- Fgf10
- Fgf17
- Fgf18
- Fgf2
- Fgf22
- Fgf23
- Fgf3
- Fgf4
- Fgf5
- Fgf8
- Fgfr5
- Fgfrl1
- Int-2
- Kfgf
- Spred1
- Spred2
|
|
Serine biosynthesis
|
|
|
- Aigp1
- Aigp2
- Aigp3
- Diff33
- Phgdh
- Psa
- Psat
- Psat1
- Psph
- Serinc1
- Serinc2
- Serinc3
- Serinc4
- Serinc5
- Srr
- Tde1
- Tde1l
- Tde2
- Tde2l
- Tms1
- Tms2
|
|
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
|
|
|
- Aik
- Aik2
- Aim1
- Airk1
- Airk2
- Anapc1
- Anapc10
- Anapc11
- Anapc15
- Anapc16
- Anapc2
- Anapc4
- Anapc5
- Anapc6
- Anapc7
- Anapc8
- Apc10
- Apc7
- Ark1
- Ark2
- Aura
- Aurka
- Aurkb
- Ayk1
- Btak
- Cdc16
- Cdc20
- Cdc23
- Cdc26
- Cdc27
- D10Ertd641e
- D5Ertd249e
- E2epf
- Fyr
- Fzr
- Fzr1
- Iak1
- Kiaa0072
- Kiaa0077
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mcpr
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- P91a
- Pa28b1
- Pad1
- Plk
- Plk1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Pttg
- Pttg1
- Rb-1
- Rb1
- Ring12
- Rps27a
- Skp2
- Stk1
- Stk12
- Stk15
- Stk5
- Stk6
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tsg24
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubce5
- Ubcep1
- Ubcep2
- Ubch10
- Ubcm3
- Ube2c
- Ube2d1
- Ube2e1
- Ube2s
|
|
Regulation of TP53 Activity through Phosphorylation
|
|
|
- Aik
- Aik2
- Aim1
- Airk1
- Airk2
- Ark1
- Ark2
- Atm
- Atr
- Atrip
- Aura
- Aurka
- Aurkb
- Ayk1
- Bach1
- Bard1
- Blm
- Brca1
- Brip1
- Btak
- Ccg1
- Ccna
- Ccna1
- Ccna2
- Cdk2
- Cdk5
- Cdk5r
- Cdk5r1
- Cdkn2
- Cdkn5
- Chek1
- Chek2
- Chk1
- Chk2
- Ck2n
- Ckiia
- Cnk
- Crk1
- Crk6
- Csbp1
- Csbp2
- Csnk2a1
- Csnk2a2
- Csnk2b
- Ctip
- Cyca
- Cyca2
- Dna2
- Dna2l
- Dyrk2
- Exo1
- Fact140
- Factp140
- Fancj
- Fnk
- Gm929
- Hipk1
- Hipk2
- Htatip
- Hus1
- Iak1
- Kat5
- Kiaa0083
- Kiaa0259
- Kiaa0537
- Kiaa0630
- Kiaa4069
- Lkb1
- Mapk11
- Mapk14
- Mapkapk5
- Mdm2
- Mdm4
- Mdmx
- Mre11
- Mre11a
- Myak
- Nbak1
- Nbak2
- Nbn
- Nbs1
- Nck5a
- Nir
- Noc2l
- Nuak1
- Omphk1
- P53
- PSSALRE
- Pin1
- Plk3
- Prkaa1
- Prkaa2
- Prkaac
- Prkab1
- Prkab2
- Prkag1
- Prkag2
- Prkag3
- Prkm11
- Prpk
- Rad1
- Rad17
- Rad50
- Rad53
- Rad9
- Rad9a
- Rad9b
- Rbbp8
- Rec1
- Rfc2
- Rfc3
- Rfc4
- Rfc5
- Rhno1
- Rmi1
- Rmi2
- Rpa1
- Rpa2
- Rpa3
- Rpa34
- Rps27a
- Sip
- Ssrp1
- Stank
- Stk1
- Stk11
- Stk12
- Stk15
- Stk5
- Stk6
- Supt16
- Supt16h
- Taf1
- Taf10
- Taf11
- Taf12
- Taf13
- Taf15
- Taf2
- Taf2c2
- Taf2e
- Taf2f
- Taf2g
- Taf2h
- Taf2k
- Taf3
- Taf4
- Taf4a
- Taf4b
- Taf5
- Taf6
- Taf7
- Taf7l2
- Taf9
- Taf9b
- Taf9l
- Tafii105
- Tafii30
- Tbp
- Tfiid
- Tip60
- Top3
- Top3a
- Topbp1
- Tp53
- Tp53rk
- Tp53rkb
- Tpx2
- Trp53
- Trp53inp1
- Trp53rk
- Trp53rkb
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Wrn
|
|
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
|
|
|
- Aik
- Airk1
- Ark1
- Aura
- Aurka
- Ayk1
- Bax
- Btak
- Ccn-2
- Ccnb1
- Ccnb1-rs13
- Cdc2
- Cdc2a
- Cdk1
- Cdkn1
- Cycb
- Cycb1
- Ddit1
- Gadd45
- Gadd45a
- Iak1
- Mkrn3
- Pcna
- Sfn
- Stk15
- Stk6
|
|
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
|
|
|
- Aik
- Airk1
- Ark1
- Aura
- Aurka
- Ayk1
- Btak
- Cul1
- Fbxl18
- Fbxl7
- Iak1
- Kiaa0072
- Kiaa0077
- Kiaa0840
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Rbx1
- Ring12
- Rps27a
- Skp1
- Skp1a
- Stk15
- Stk6
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Costimulation by the CD28 family
|
|
|
- Ailim
- B7h2
- B7rp1
- Btla
- Hcp
- Hcph
- Icos
- Icosl
- Icoslg
- Pik3ca
- Pik3r1
- Pik3r2
- Pik3r3
- Ptp1C
- Ptpn11
- Ptpn6
- Tnfrsf14
- hvem
|
|
Melanin biosynthesis
|
|
|
- Aim1
- Dct
- Matp
- Oca2
- P
- Slc45a2
- Tyr
- Tyrp-1
- Tyrp-2
- Tyrp1
- Tyrp2
- uw
|
|
Cytosolic sensors of pathogen-associated DNA
|
|
|
- Aim2
- Gm1313
- Ifi210
- Mre11
- Mre11a
|
|
Transcriptional and post-translational regulation of MITF-M expression and activity
|
|
|
- Aimp1
- Aimp2
- Cbp
- Crebbp
- Crm1
- Dars
- Dars1
- Eef1e1
- Emap2
- Eprs
- Eprs1
- Erk1
- Erk2
- Gsk3b
- Hint
- Hint1
- Iars
- Iars1
- Jtv1
- Kars
- Kars1
- Kit
- Kitl
- Kitlg
- Lars
- Lars1
- Mapk
- Mapk1
- Mapk3
- Mapkapk1a
- Mars
- Mars1
- Mgf
- Pkci
- Pkci1
- Prkcnh1
- Prkm1
- Prkm3
- Qars
- Qars1
- Qprs
- Rars
- Rars1
- Rps6ka1
- Rsk1
- Scye1
- Sl
- Slf
- Wnt-3a
- Wnt3a
- Xpo1
|
|
Mitochondrial translation elongation
|
|
|
- Aip
- Akip
- Aurkaip1
- Chchd1
- D10Ertd322e
- D9Wsu149
- Dap3
- Efg
- Efg1
- Eral1
- Gadd45gip1
- Gdap3
- Gfm
- Gfm1
- Heg1
- Ict1
- Imogn38
- Kgd4
- L23mrp
- Mera
- Mrp63
- Mrp64
- Mrpl1
- Mrpl10
- Mrpl11
- Mrpl12
- Mrpl13
- Mrpl14
- Mrpl15
- Mrpl16
- Mrpl17
- Mrpl18
- Mrpl19
- Mrpl2
- Mrpl20
- Mrpl21
- Mrpl22
- Mrpl23
- Mrpl24
- Mrpl27
- Mrpl28
- Mrpl3
- Mrpl30
- Mrpl32
- Mrpl33
- Mrpl34
- Mrpl35
- Mrpl36
- Mrpl37
- Mrpl38
- Mrpl39
- Mrpl4
- Mrpl40
- Mrpl41
- Mrpl42
- Mrpl43
- Mrpl44
- Mrpl45
- Mrpl46
- Mrpl47
- Mrpl48
- Mrpl49
- Mrpl50
- Mrpl51
- Mrpl52
- Mrpl53
- Mrpl54
- Mrpl55
- Mrpl57
- Mrpl58
- Mrpl59
- Mrpl9
- Mrps10
- Mrps11
- Mrps12
- Mrps14
- Mrps15
- Mrps16
- Mrps17
- Mrps18a
- Mrps18b
- Mrps18c
- Mrps2
- Mrps21
- Mrps22
- Mrps23
- Mrps24
- Mrps25
- Mrps26
- Mrps27
- Mrps28
- Mrps29
- Mrps30
- Mrps31
- Mrps32
- Mrps33
- Mrps34
- Mrps35
- Mrps36
- Mrps37
- Mrps38
- Mrps39
- Mrps5
- Mrps6
- Mrps7
- Mrps9
- Nlvcf
- Oxa1l
- Ptcd3
- Rpml12
- Rpms12
- Rpms15
- Rpms16
- Rpms17
- Rpms21
- Rpms22
- Rpms25
- Rpms6
- Tce2
|
|
Mitochondrial translation termination
|
|
|
- Aip
- Akip
- Aurkaip1
- Chchd1
- D10Ertd322e
- D9Wsu149
- Dap3
- Efg2
- Eral1
- Gadd45gip1
- Gdap3
- Gfm2
- Heg1
- Ict1
- Imogn38
- Kgd4
- L23mrp
- Mera
- Mrp63
- Mrp64
- Mrpl1
- Mrpl10
- Mrpl11
- Mrpl12
- Mrpl13
- Mrpl14
- Mrpl15
- Mrpl16
- Mrpl17
- Mrpl18
- Mrpl19
- Mrpl2
- Mrpl20
- Mrpl21
- Mrpl22
- Mrpl23
- Mrpl24
- Mrpl27
- Mrpl28
- Mrpl3
- Mrpl30
- Mrpl32
- Mrpl33
- Mrpl34
- Mrpl35
- Mrpl36
- Mrpl37
- Mrpl38
- Mrpl39
- Mrpl4
- Mrpl40
- Mrpl41
- Mrpl42
- Mrpl43
- Mrpl44
- Mrpl45
- Mrpl46
- Mrpl47
- Mrpl48
- Mrpl49
- Mrpl50
- Mrpl51
- Mrpl52
- Mrpl53
- Mrpl54
- Mrpl55
- Mrpl57
- Mrpl58
- Mrpl59
- Mrpl9
- Mrps10
- Mrps11
- Mrps12
- Mrps14
- Mrps15
- Mrps16
- Mrps17
- Mrps18a
- Mrps18b
- Mrps18c
- Mrps2
- Mrps21
- Mrps22
- Mrps23
- Mrps24
- Mrps25
- Mrps26
- Mrps27
- Mrps28
- Mrps29
- Mrps30
- Mrps31
- Mrps32
- Mrps33
- Mrps34
- Mrps35
- Mrps36
- Mrps37
- Mrps38
- Mrps39
- Mrps5
- Mrps6
- Mrps7
- Mrps9
- Mrrf
- Mtrf1l
- Nlvcf
- Oxa1l
- Ptcd3
- Rpml12
- Rpms12
- Rpms15
- Rpms16
- Rpms17
- Rpms21
- Rpms22
- Rpms25
- Rpms6
- Tce2
|
|
Regulation of necroptotic cell death
|
|
|
- Aip1
- Aipa
- Alix
- Api3
- Birc2
- Birc3
- Birc4
- Casp8
- Cdc37
- Chip
- Esa1
- Fadd
- Flot1
- Flot2
- Hsp86
- Hsp86-1
- Hsp90aa1
- Hspca
- Itch
- M17s1
- Miha
- Mlkl
- Mort1
- Ogt
- Park2
- Pdcd6ip
- Peli1
- Prkn
- Rinp
- Rip
- Rip3
- Ripk1
- Ripk3
- Rps27a
- Sdcbp
- Stub1
- Tradd
- Traf2
- Uba52
- Uba80
- Ubb
- Ubc
- Ubce7
- Ubcep1
- Ubcep2
- Ube2l3
- Xiap
|
|
RIPK1-mediated regulated necrosis
|
|
|
- Aip1
- Alix
- Esa1
- Flot1
- Flot2
- M17s1
- Mlkl
- Pdcd6ip
- Rinp
- Rip
- Rip3
- Ripk1
- Ripk3
- Sdcbp
|
|
Glutamate Neurotransmitter Release Cycle
|
|
|
- Aip5
- Arl6ip5
- Ata2
- Bnpi
- Bzrap1
- Cplx1
- Eaac1
- Eaat1
- Eaat2
- Eaat3
- Eaat4
- Gls
- Gls1
- Gls2
- Glt1
- Gmt1
- Jwa
- Kiaa0340
- Kiaa0612
- Kiaa0838
- Kiaa1382
- Kiaa4146
- Ppfia1
- Ppfia2
- Ppfia3
- Ppfia4
- Pra2
- Praf3
- Rab3a
- Rab3ip1
- Rbp1
- Rim1
- Rims1
- Sat2
- Slc17a7
- Slc1a1
- Slc1a2
- Slc1a3
- Slc1a6
- Slc1a7
- Slc38a2
- Snap
- Snap25
- Snat2
- Stx1a
- Stxbp1
- Syb2
- Syt1
- Tspoap1
- Unc13a
- Unc13b
- Vamp2
- Vglut1
- ppfia4
|
|
Regulation of PTEN stability and activity
|
|
|
- Aipa
- Akt
- Akt1
- Akt2
- Akt3
- Api3
- Birc4
- Bsk
- Chip
- Ck2n
- Ckiia
- Csnk2a1
- Csnk2a2
- Csnk2b
- Depdc2
- Frk
- Iyk
- Kiaa0072
- Kiaa0077
- Kiaa0093
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Miha
- Mkrn1
- Mmac1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Nedd-4
- Nedd4
- Nedd4-1
- Nedd4a
- Otud3
- P91a
- Pa28b1
- Pad1
- Prex2
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Pten
- Rac
- Rfp
- Ring12
- Rnf146
- Rpf1
- Rps27a
- Stub1
- Sug1
- Sug2
- Tank2
- Tbp1
- Tbp7
- Tnks
- Tnks1
- Tnks2
- Trim27
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Usp13
- Wwp2
- Xiap
|
|
Deactivation of the beta-catenin transactivating complex
|
|
|
- Aipa
- Akt
- Akt1
- Akt2
- Apc
- Api3
- Birc4
- Catnb
- Catnbip1
- Cby
- Cby1
- Chd8
- Crm1
- Ctbp1
- Ctnnb1
- Ctnnbip1
- Esg
- Grg1
- Grg2
- Grg4
- Hdac1
- Icat
- Kiaa1564
- Lef1
- Miha
- Pgea1
- Rac
- Rps27a
- Sox-13
- Sox-17
- Sox-2
- Sox-3
- Sox-4
- Sox-6
- Sox-7
- Sox-9
- Sox13
- Sox17
- Sox2
- Sox3
- Sox4
- Sox6
- Sox7
- Sox9
- Tcf-1
- Tcf1
- Tcf3
- Tcf4
- Tcf7
- Tcf7l1
- Tcf7l2
- Tle1
- Tle2
- Tle3
- Tle4
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Xiap
- Xpo1
- Ywhaz
|
|
Regulation of the apoptosome activity
|
|
|
- Aipa
- Apaf1
- Api3
- Apip
- Aven
- Birc4
- Casp9
- Cycs
- Diablo
- Erk1
- Erk2
- Mapk
- Mapk1
- Mapk3
- Mch6
- Miha
- Mmrp19
- Prkm1
- Prkm3
- Smac
- Xiap
|
|
Activation of caspases through apoptosome-mediated cleavage
|
|
|
- Aipa
- Apaf1
- Api3
- Birc4
- Casp3
- Casp7
- Casp9
- Cpp32
- Cycs
- Lice2
- Mch3
- Mch6
- Miha
- Xiap
|
|
SMAC, XIAP-regulated apoptotic response
|
|
|
- Aipa
- Api3
- Bh5
- Birc4
- Casp3
- Casp7
- Cpp32
- Diablo
- Gm11492
- Lice2
- Mch3
- Miha
- Pnutl2
- Sep4
- Sept4
- Septin4
- Smac
- Xiap
|
|
Regulation of TNFR1 signaling
|
|
|
- Aipa
- Api3
- Birc2
- Birc3
- Birc4
- Cash
- Casp8
- Cflar
- Chip
- Chuk
- Clip3
- Clipr59
- Cyld
- Cyld1
- Fadd
- Gnb2-rs1
- Gnb2l1
- Ikbkb
- Ikbke
- Ikbkg
- Ikka
- Ikkb
- Ikke
- Ikki
- Imp3
- Kiaa0358
- Kiaa0849
- Madd
- Mapkapk2
- Mib2
- Miha
- Mort1
- Nemo
- Optn
- Otud1
- Otud7b
- Paul
- Psl2
- Rack1
- Rbck
- Rbck1
- Rinp
- Rip
- Ripk1
- Rnf31
- Rps27a
- Rps6kc1
- Skd
- Spata2
- Sppl2a
- Sppl2b
- Stub1
- Tax1bp1
- Tbk1
- Tnf
- Tnfa
- Tnfaip3
- Tnfip3
- Tnfr-1
- Tnfr1
- Tnfrsf1a
- Tnfsf2
- Tradd
- Traf1
- Traf2
- Uba52
- Uba80
- Ubb
- Ubc
- Ubc4
- Ubce7
- Ubce7ip3
- Ubcep1
- Ubcep2
- Ubch4
- Ubch5b
- Ube2d1
- Ube2d2
- Ube2d2a
- Ube2d3
- Ube2l3
- Ubp41
- Uip28
- Ulk1
- Unp
- Usp2
- Usp21
- Usp23
- Usp4
- Xiap
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TNFR1-induced NF-kappa-B signaling pathway
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- Aipa
- Api3
- Birc2
- Birc3
- Birc4
- Chuk
- Cyld
- Cyld1
- Gnb2-rs1
- Gnb2l1
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Kiaa0733
- Kiaa0849
- Kiaa4135
- Map3k7
- Map3k7ip1
- Map3k7ip2
- Map3k7ip3
- Miha
- Nemo
- Optn
- Otud1
- Otud7b
- Paul
- Rack1
- Rbck
- Rbck1
- Rinp
- Rip
- Ripk1
- Rnf31
- Spata2
- Tab1
- Tab2
- Tab3
- Tak1
- Tnf
- Tnfa
- Tnfaip3
- Tnfip3
- Tnfr-1
- Tnfr1
- Tnfrsf1a
- Tnfsf2
- Tradd
- Traf1
- Traf2
- Ubce7ip3
- Ubp41
- Uip28
- Unp
- Usp2
- Usp21
- Usp23
- Usp4
- Xiap
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TNFR1-induced proapoptotic signaling
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- Aipa
- Api3
- Birc2
- Birc3
- Birc4
- Cyld
- Cyld1
- Fadd
- Ikbke
- Ikke
- Ikki
- Kiaa0849
- Mib2
- Miha
- Mort1
- Otud1
- Otud7b
- Paul
- Rbck
- Rbck1
- Rinp
- Rip
- Ripk1
- Rnf31
- Skd
- Spata2
- Tbk1
- Tnf
- Tnfa
- Tnfaip3
- Tnfip3
- Tnfr-1
- Tnfr1
- Tnfrsf1a
- Tnfsf2
- Tradd
- Traf2
- Ubce7ip3
- Ubp41
- Uip28
- Unp
- Usp2
- Usp21
- Usp23
- Usp4
- Xiap
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SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
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- Aipa
- Api3
- Birc4
- Casp7
- Diablo
- Lice2
- Mch3
- Miha
- Smac
- Xiap
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