Polo-like kinase mediated events
|
|
|
- Cdc25c
- Cdc25m1
- Fkh16
- Foxm1
- Myt1
- Pkmyt1
- Plk
- Plk1
- Wee1
|
|
Detoxification of Reactive Oxygen Species
|
|
|
- Aop1
- Aop2
- Apah1
- Cas-1
- Cas1
- Cat
- Ccs
- Ccsd
- Cgd
- Cyba
- Cybb
- Cycs
- Ero1a
- Ero1l
- Gpx1
- Gpx2
- Gpx3
- Gpx5
- Gpx6
- Gpx7
- Gpx8
- Gr1
- Gsr
- Gstp1
- Gstp2
- Gstpia
- Gstpib
- Ltw4
- Mer5
- Msp23
- Ncf1
- Ncf2
- Ncf4
- Nox4
- Noxa2
- Nudt2
- P4hb
- P67phox
- Paga
- Pdia1
- Prdx1
- Prdx2
- Prdx3
- Prdx5
- Prdx6
- Renox
- Sod-2
- Sod1
- Sod2
- Sod3
- Tdpx1
- Tdpx2
- Tpx
- Trxr1
- Trxr2
- Txn
- Txn1
- Txn2
- Txnrd1
- Txnrd2
|
|
Triglyceride catabolism
|
|
|
- Ap2
- Blbp
- Fabp1
- Fabp12
- Fabp2
- Fabp3
- Fabp4
- Fabp5
- Fabp6
- Fabp7
- Fabp9
- Fabpe
- Fabph1
- Fabpi
- Fabpl
- Gdm1
- Gpd2
- Illbp
- Klbp
- Mal1
- Perf15
- Pnpla5
- Tlbp
|
|
Glycoprotein hormones
|
|
|
- Cga
- Fshb
- Inha
- Inhba
- Inhbb
- Inhbc
- Inhbe
- Lhb
- Tshb
|
|
Pyroptosis
|
|
|
- Bak
- Bak1
- Bax
- Casp1
- Casp11
- Casp3
- Casp4
- Caspl
- Chmp2a
- Chmp2b
- Chmp3
- Chmp4b
- Chmp4c
- Chmp6
- Chmp7
- Cpp32
- Ctla-1
- Ctla1
- Cycs
- Dfna5
- Dfna5h
- Ela2
- Elane
- Gsdmd
- Gsdmdc1
- Gsdme
- Gzmb
- Hmg-1
- Hmg1
- Hmgb1
- Ich3
- Igif
- Il18
- Il1a
- Il1b
- Il1bc
- Vps24
|
|
Release of apoptotic factors from the mitochondria
|
|
|
- Bak
- Bak1
- Bax
- Bh5
- Cycs
- Dfna5
- Dfna5h
- Diablo
- Gm11492
- Gsdmd
- Gsdmdc1
- Gsdme
- Pnutl2
- Sep4
- Sept4
- Septin4
- Smac
|
|
Caspase-mediated cleavage of cytoskeletal proteins
|
|
|
- Add1
- Argbp2
- Casp3
- Casp6
- Casp7
- Casp8
- Cpp32
- Gas-2
- Gas2
- Gsb
- Gsn
- Kiaa0777
- Lice2
- Mapt
- Mch2
- Mch3
- Mtapt
- Plec
- Plec1
- Sorbs2
- Spna2
- Spta2
- Sptan1
- Tau
- Vim
|
|
Apoptotic cleavage of cellular proteins
|
|
|
- Acin1
- Acinus
- Apc
- Bap31
- Bcap31
- Birc2
- Bmx
- Casp3
- Casp6
- Casp7
- Casp8
- Clspn
- Cpp32
- Fnta
- Lice2
- Mch2
- Mch3
- Mst3
- Mst4
- Pkcd
- Pkcq
- Prkcd
- Prkcq
- Rock1
- Satb1
- Stk24
- Stk26
- Stk3
|
|
Breakdown of the nuclear lamina
|
|
|
- Casp6
- Lmn1
- Lmna
- Lmnb1
- Mch2
|
|
Purine salvage
|
|
|
- Ada
- Adal
- Adk
- Ampd1
- Ampd2
- Ampd3
- Aprt
- Dck
- Dgk
- Dguok
- Gmpr
- Gmpr1
- Gmpr2
- Hprt
- Hprt1
- Np
- Pnp
- Pnp1
- Pnp2
|
|
TP53 Regulates Transcription of DNA Repair Genes
|
- CDK-activating kinase assembly factor MAT1
- Cyclin-H
- Cyclin-K
- Cyclin-T1
- Cyclin-T2
- Cyclin-dependent kinase 12
- Cyclin-dependent kinase 13
- Cyclin-dependent kinase 7
- Cyclin-dependent kinase 9
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Elongin-A
- Elongin-B
- Elongin-C
- FACT complex subunit SPT16
- FACT complex subunit SSRP1
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit 2
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 4
- General transcription factor IIH subunit 5
- Negative elongation factor A
- Negative elongation factor B
- Negative elongation factor D
- Negative elongation factor E
- RNA polymerase II elongation factor ELL
- RNA polymerase II subunit A C-terminal domain phosphatase
- Transcription elongation factor A protein 1
- Transcription elongation factor SPT4-A
- Transcription elongation factor SPT5
|
|
- Btf2p44
- Cak
- Ccnh
- Ccnk
- Ccnt1
- Ccnt2
- Cdc2l5
- Cdk12
- Cdk13
- Cdk7
- Cdk9
- Cdkn7
- Cobra1
- Crk4
- Crk7
- Crkrs
- Ctdp1
- D17Wsu155e
- D17h6s45
- Ell
- Eloa
- Elob
- Eloc
- Ercc2
- Ercc3
- Fact140
- Factp140
- Fcp1
- Gtf2f1
- Gtf2f2
- Gtf2h1
- Gtf2h2
- Gtf2h3
- Gtf2h4
- Gtf2h5
- Kiaa0904
- Kiaa1791
- Mat1
- Mnat1
- Mo15
- Mpk-7
- Mt1a
- Nelfa
- Nelfb
- Nelfcd
- Nelfd
- Nelfe
- Polr2a
- Polr2b
- Polr2c
- Polr2d
- Polr2e
- Polr2f
- Polr2g
- Polr2h
- Polr2i
- Polr2j
- Polr2k
- Polr2l
- Rd
- Rdbp
- Rpii215
- Rpo2-1
- Rpo2-3
- Rpo2-4
- Spt4h
- Ssrp1
- Supt16
- Supt16h
- Supt4a
- Supt4h
- Supt4h1a
- Supt5
- Supt5h
- Tcea1
- Tceat
- Tceb1
- Tceb2
- Tceb3
- Th1
- Th1l
- Whsc2
- Whsc2h
- Xpb
- Xpbc
- Xpd
|
|
mRNA Capping
|
- CDK-activating kinase assembly factor MAT1
- Cyclin-H
- Cyclin-dependent kinase 7
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit 2
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 4
- General transcription factor IIH subunit 5
- Nuclear cap-binding protein subunit 1
- Nuclear cap-binding protein subunit 2
- Transcription elongation factor SPT5
- mRNA cap guanine-N7 methyltransferase
- mRNA-capping enzyme
|
|
- Btf2p44
- Cak
- Cap1a
- Cbp20
- Cbp80
- Ccnh
- Cdk7
- Cdkn7
- Crk4
- D17Wsu155e
- Ercc2
- Ercc3
- Gtf2f1
- Gtf2f2
- Gtf2h1
- Gtf2h2
- Gtf2h3
- Gtf2h4
- Gtf2h5
- Kiaa0398
- Mat1
- Mnat1
- Mo15
- Mpk-7
- Mt1a
- Ncbp1
- Ncbp2
- Polr2a
- Polr2b
- Polr2c
- Polr2d
- Polr2e
- Polr2f
- Polr2g
- Polr2h
- Polr2i
- Polr2j
- Polr2k
- Polr2l
- Rngtt
- Rnmt
- Rpii215
- Rpo2-1
- Rpo2-3
- Rpo2-4
- Supt5
- Supt5h
- Xpb
- Xpbc
- Xpd
|
|
RNA Pol II CTD phosphorylation and interaction with CE
|
- CDK-activating kinase assembly factor MAT1
- Cyclin-H
- Cyclin-dependent kinase 7
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit 2
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 4
- General transcription factor IIH subunit 5
- Transcription elongation factor SPT5
- mRNA cap guanine-N7 methyltransferase
- mRNA-capping enzyme
|
|
- Btf2p44
- Cak
- Cap1a
- Ccnh
- Cdk7
- Cdkn7
- Crk4
- D17Wsu155e
- Ercc2
- Ercc3
- Gtf2f1
- Gtf2f2
- Gtf2h1
- Gtf2h2
- Gtf2h3
- Gtf2h4
- Gtf2h5
- Kiaa0398
- Mat1
- Mnat1
- Mo15
- Mpk-7
- Mt1a
- Polr2a
- Polr2b
- Polr2c
- Polr2d
- Polr2e
- Polr2f
- Polr2g
- Polr2h
- Polr2i
- Polr2j
- Polr2k
- Polr2l
- Rngtt
- Rnmt
- Rpii215
- Rpo2-1
- Rpo2-3
- Rpo2-4
- Supt5
- Supt5h
- Xpb
- Xpbc
- Xpd
|
|
Formation of the Early Elongation Complex
|
- CDK-activating kinase assembly factor MAT1
- Cyclin-H
- Cyclin-dependent kinase 7
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit 2
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 4
- General transcription factor IIH subunit 5
- Negative elongation factor A
- Negative elongation factor B
- Negative elongation factor D
- Negative elongation factor E
- Nuclear cap-binding protein subunit 1
- Nuclear cap-binding protein subunit 2
- RNA polymerase II subunit A C-terminal domain phosphatase
- Transcription elongation factor SPT4-A
- Transcription elongation factor SPT5
|
|
- Btf2p44
- Cak
- Cbp20
- Cbp80
- Ccnh
- Cdk7
- Cdkn7
- Cobra1
- Crk4
- Ctdp1
- D17Wsu155e
- D17h6s45
- Ercc2
- Ercc3
- Fcp1
- Gtf2f1
- Gtf2f2
- Gtf2h1
- Gtf2h2
- Gtf2h3
- Gtf2h4
- Gtf2h5
- Mat1
- Mnat1
- Mo15
- Mpk-7
- Mt1a
- Ncbp1
- Ncbp2
- Nelfa
- Nelfb
- Nelfcd
- Nelfd
- Nelfe
- Polr2a
- Polr2b
- Polr2c
- Polr2d
- Polr2e
- Polr2f
- Polr2g
- Polr2h
- Polr2i
- Polr2j
- Polr2k
- Polr2l
- Rd
- Rdbp
- Rpii215
- Rpo2-1
- Rpo2-3
- Rpo2-4
- Spt4h
- Supt4a
- Supt4h
- Supt4h1a
- Supt5
- Supt5h
- Th1
- Th1l
- Whsc2
- Whsc2h
- Xpb
- Xpbc
- Xpd
|
|
FGFR2 alternative splicing
|
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- Heterogeneous nuclear ribonucleoprotein A1
- Nuclear cap-binding protein subunit 1
- Nuclear cap-binding protein subunit 2
- Polypyrimidine tract-binding protein 1
|
|
- Cbp20
- Cbp80
- Fli-2
- Gtf2f1
- Gtf2f2
- Hnrnpa1
- Hnrpa1
- Mt1a
- Ncbp1
- Ncbp2
- Polr2a
- Polr2b
- Polr2c
- Polr2d
- Polr2e
- Polr2f
- Polr2g
- Polr2h
- Polr2i
- Polr2j
- Polr2k
- Polr2l
- Ptb
- Ptbp1
- Rpii215
- Rpo2-1
- Rpo2-3
- Rpo2-4
- Tis
|
|
Intrinsic Pathway of Fibrin Clot Formation
|
|
|
- A2m
- A2mp
- At3
- C1nh
- C1qbp
- Cf2
- Cf8
- Cf9
- F10
- F11
- F12
- F2
- F8
- F8c
- F9
- Gc1qbp
- Gp1ba
- Gp1bb
- Gp5
- Gp9
- Hcf2
- Hcii
- Klk3
- Klkb1
- Kng2
- Pci
- Pi7
- Pk
- Pn1
- Prcp
- Proc
- Pros
- Pros1
- Serpina5
- Serpinc1
- Serpind1
- Serpine2
- Serping1
- Spi4
- Vwf
|
|
GP1b-IX-V activation signalling
|
|
|
- Craf
- Fln
- Fln1
- Flna
- Gp1ba
- Gp1bb
- Gp5
- Gp9
- Pik3r1
- Raf1
- Src
- Vwf
- Ywhaz
|
|
Platelet Adhesion to exposed collagen
|
|
|
- Adamts13
- Fce1g
- Fcer1g
- Fyn
- Gm710
- Gp1ba
- Gp1bb
- Gp5
- Gp6
- Gp9
- Lyn
- Vwf
|
|
Platelet Aggregation (Plug Formation)
|
|
|
- Cf2
- F2
- Gp1ba
- Gp1bb
- Gp5
- Gp9
- Vwf
|
|
Branched-chain amino acid catabolism
|
- 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
- 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
- 3-hydroxyacyl-CoA dehydrogenase type-2
- 3-hydroxyisobutyrate dehydrogenase, mitochondrial
- 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
- Acetyl-CoA acetyltransferase, mitochondrial
- Branched-chain alpha-ketoacid dehydrogenase kinase
- Branched-chain-amino-acid aminotransferase, cytosolic
- Branched-chain-amino-acid aminotransferase, mitochondrial
- Dihydrolipoyl dehydrogenase, mitochondrial
- Enoyl-CoA hydratase, mitochondrial
- Isobutyryl-CoA dehydrogenase, mitochondrial
- Isovaleryl-CoA dehydrogenase, mitochondrial
- Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
- Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial
- Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
- Methylglutaconyl-CoA hydratase, mitochondrial
- Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial
- Protein phosphatase Mn(2+)-dependent 1K
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
|
|
- Acad8
- Acadsb
- Acat1
- Aldh6a1
- Auh
- Bcat1
- Bcat2
- Bcatm
- Bckdha
- Bckdhb
- Bckdk
- Dbt
- Dld
- Eca39
- Eca40
- Echs1
- Erab
- Hadh2
- Hibadh
- Hibch
- Hsd17b10
- Ivd
- Mcca
- Mccc1
- Mccc2
- Pp2cm
- Ppm1k
|
|
Signaling by Retinoic Acid
|
- Carnitine O-palmitoyltransferase 1, liver isoform
- Carnitine O-palmitoyltransferase 1, muscle isoform
- Cellular retinoic acid-binding protein 2
- Dihydrolipoyl dehydrogenase, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- Fatty acid-binding protein 5
- Peroxisome proliferator-activated receptor delta
- Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Pyruvate dehydrogenase protein X component, mitochondrial
- Retinoic acid receptor RXR-alpha
- Retinoic acid receptor RXR-beta
- Retinoic acid receptor RXR-gamma
- Retinoic acid receptor alpha
- Retinoic acid receptor beta
- Retinoic acid receptor gamma
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
|
|
- Cpt-1
- Cpt1
- Cpt1a
- Cpt1b
- Crabp2
- Dlat
- Dld
- Fabp5
- Fabpe
- Klbp
- Mal1
- Nr1b1
- Nr1b2
- Nr1b3
- Nr1c2
- Nr2b1
- Nr2b2
- Nr2b3
- Pdha-1
- Pdha-2
- Pdha1
- Pdha2
- Pdhal
- Pdhb
- Pdhx
- Pdk1
- Pdk2
- Pdk3
- Pdk4
- Pparb
- Ppard
- Rara
- Rarb
- Rarg
- Rxra
- Rxrb
- Rxrg
|
|
Regulation of pyruvate dehydrogenase (PDH) complex
|
- Dihydrolipoyl dehydrogenase, mitochondrial
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- Maleylacetoacetate isomerase
- NAD-dependent protein lipoamidase sirtuin-4, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial
- Pyruvate dehydrogenase protein X component, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
- [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
- [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial
|
|
- Dlat
- Dld
- Gstz1
- Kiaa1990
- Maai
- Pdha-1
- Pdha-2
- Pdha1
- Pdha2
- Pdhal
- Pdhb
- Pdhx
- Pdk1
- Pdk2
- Pdk3
- Pdk4
- Pdp1
- Pdp2
- Pdpr
- Ppm2c
- Sir2l4
- Sirt4
|
|
PDH complex synthesizes acetyl-CoA from PYR
|
|
|
- Dlat
- Dld
- Pdha-1
- Pdha-2
- Pdha1
- Pdha2
- Pdhal
- Pdhb
- Pdhx
|
|
Glycine degradation
|
|
|
- Amt
- Dld
- Dlst
- Gcsh
- Gldc
- Kgd4
- Kiaa4192
- Mrps36
- Ogdh
|
|
Succinyl-CoA Biosynthesis
|
|
|
- Dld
- Dlst
- Kgd4
- Kiaa4192
- Mrps36
- Ogdh
|
|