RHOH GTPase cycle
|
|
|
- Aaat
- Arhgdia
- Arhgdib
- Arhgdig
- Arhh
- Asct2
- Brwd2
- C87222
- Cav
- Cav1
- Csk
- D15Ertd621e
- Dbt
- Epb7.2
- Epb72
- Fam91a1
- Garnl1
- Gbas
- Gdi1
- Gdi5
- Gdid4
- Jup
- Kiaa0493
- Kiaa0884
- Kiaa1142
- Kiaa1351
- Kiaa1561
- Lamtor1
- Lck
- Lpp2
- Lsk-t
- Mtr
- Nbc3
- Nipsnap2
- Nsfl1c
- ORF18
- Osbpl11
- Pak1
- Pak2
- Pak4
- Pak5
- Pak6
- Pak7
- Paka
- Rab7
- Rab7a
- Ralgapa1
- Rhoh
- Rock1
- Rock2
- Slc1a5
- Slc1a7
- Slc4a7
- Srk
- Stom
- Syb3
- Tdcf1
- Tfrc
- Tmem59
- Trfr
- Tuba1b
- Tuba2
- Tulip1
- Uaca
- Vamp3
- Vangl1
- Vcp
- Wdr11
- Zap-70
- Zap70
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|
Activation of the TFAP2 (AP-2) family of transcription factors
|
|
|
- Ap2tf
- Cbp
- Cited1
- Cited2
- Cited4
- Crebbp
- Ep300
- Gas41
- Mrg1
- Mrg2
- Msg1
- Msg2
- P300
- Tcfap2a
- Tcfap2b
- Tcfap2c
- Tcfap2d
- Tcfap2e
- Tfap2a
- Tfap2b
- Tfap2c
- Tfap2d
- Tfap2e
- Wox1
- Wwox
- Yeats4
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Estrogen-dependent gene expression
|
- Cbp/p300-interacting transactivator 1
- Core-binding factor subunit beta
- Cyclin-T1
- Cyclin-dependent kinase 9
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Estrogen receptor
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- Heat shock protein HSP 90-alpha
- Heat shock protein HSP 90-beta
- Hepatocyte nuclear factor 3-alpha
- Histone H2A.J
- Histone H2B type 1-A
- Histone H2B type 1-B
- Histone H2B type 1-C/E/G
- Histone H2B type 1-F/J/L
- Histone H2B type 1-H
- Histone H2B type 1-K
- Histone H2B type 1-M
- Histone H2B type 1-P
- Histone H2B type 2-E
- Histone H2B type 3-B
- Histone H3.1
- Histone H3.2
- Histone H3.3
- Histone H4
- Histone acetyltransferase KAT2B
- Histone acetyltransferase KAT5
- Histone acetyltransferase p300
- Histone lysine acetyltransferase CREBBP
- Histone-arginine methyltransferase CARM1
- Lysine-specific histone demethylase 1A
- Mediator of RNA polymerase II transcription subunit 1
- Nuclear receptor coactivator 1
- Nuclear receptor coactivator 2
- Nuclear receptor coactivator 3
- Nuclear receptor-interacting protein 1
- Peptidyl-prolyl cis-trans isomerase FKBP4
- Probable ATP-dependent RNA helicase DDX5
- Progesterone receptor
- Prostaglandin E synthase 3
- Protein GREB1
- Protein arginine N-methyltransferase 1
- Receptor tyrosine-protein kinase erbB-4
- Runt-related transcription factor 1
- TATA-box-binding protein
- Trans-acting T-cell-specific transcription factor GATA-3
- Transcription factor Sp1
- Transcription initiation factor IIA subunit 1
- Transcription initiation factor IIA subunit 2
- Transducin-like enhancer protein 3
- Upstream stimulatory factor 1
- Upstream stimulatory factor 2
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- Aib1
- Aml1
- Aof2
- Carm1
- Cbfa2
- Cbfb
- Cbp
- Ccnt1
- Cdk9
- Cited1
- Crebbp
- Crsp210
- Ddx5
- Drip205
- Ep300
- Erbb4
- Esg
- Esr
- Esr1
- Estr
- Estra
- Fkbp4
- Fkpb52
- Foxa1
- Gata-3
- Gata3
- Greb1
- Grip1
- Gtf2a1
- Gtf2a2
- Gtf2f1
- Gtf2f2
- H2aj
- H2b-f
- H2b-j
- H2b-l
- H2b-n
- H2bc1
- H2bc11
- H2bc12
- H2bc13
- H2bc14
- H2bc15
- H2bc21
- H2bc26
- H2bc26-ps
- H2bc3
- H2bc4
- H2bc6
- H2bc7
- H2bc8
- H2bc9
- H2bu1
- H2bu1-ps
- H3-143
- H3-3a
- H3-3b
- H3-53
- H3-B
- H3-F
- H3.1-221
- H3.1-291
- H3.1-I
- H3.2
- H3.2-221
- H3.2-614
- H3.2-615
- H3.2-616
- H3.3a
- H3.3b
- H3a
- H3b
- H3c1
- H3c10
- H3c11
- H3c13
- H3c14
- H3c15
- H3c2
- H3c3
- H3c4
- H3c6
- H3c7
- H3c8
- H3f
- H3f3a
- H3f3b
- H3g
- H3h
- H3i
- H4-12
- H4-53
- H4c1
- H4c11
- H4c12
- H4c14
- H4c16
- H4c2
- H4c3
- H4c4
- H4c6
- H4c8
- H4c9
- H4f16
- Hist1h2ba
- Hist1h2bb
- Hist1h2bc
- Hist1h2be
- Hist1h2bf
- Hist1h2bg
- Hist1h2bh
- Hist1h2bj
- Hist1h2bk
- Hist1h2bl
- Hist1h2bm
- Hist1h2bn
- Hist1h2bp
- Hist1h3a
- Hist1h3b
- Hist1h3c
- Hist1h3d
- Hist1h3e
- Hist1h3f
- Hist1h3g
- Hist1h3h
- Hist1h3i
- Hist1h4a
- Hist1h4b
- Hist1h4c
- Hist1h4d
- Hist1h4f
- Hist1h4h
- Hist1h4i
- Hist1h4j
- Hist1h4k
- Hist1h4m
- Hist2h2be
- Hist2h3b
- Hist2h3c1
- Hist2h3c2
- Hist2h3ca1
- Hist2h3ca2
- Hist2h4
- Hist2h4a
- Hist3h2bb
- Hist3h2bb-ps
- Hist4h4
- Hnf3a
- Hrmt1l2
- Hsp84
- Hsp84-1
- Hsp86
- Hsp86-1
- Hsp90aa1
- Hsp90ab1
- Hspc3
- Hspca
- Hspcb
- Htatip
- Kat2b
- Kat5
- Kdm1a
- Kiaa0575
- Kiaa0601
- Lsd1
- Med1
- Mer4
- Mrmt1
- Msg1
- Mt1a
- Ncoa1
- Ncoa2
- Ncoa3
- Nr3a1
- Nr3c3
- Nrip1
- P300
- Pbp
- Pcaf
- Pcip
- Pebp2ab
- Pebp2b
- Pebpb2
- Pgr
- Polr2a
- Polr2b
- Polr2c
- Polr2d
- Polr2e
- Polr2f
- Polr2g
- Polr2h
- Polr2i
- Polr2j
- Polr2k
- Polr2l
- Pparbp
- Pr
- Prmt1
- Prmt4
- Ptges3
- Rac3
- Rpii215
- Rpo2-1
- Rpo2-3
- Rpo2-4
- Runx1
- Sid3177
- Sp1
- Src1
- Src2
- Tbp
- Tcf-3a
- Tcf3a
- Tebp
- Tfiid
- Th2b
- Tif2
- Tip60
- Tle3
- Tnz2
- Tram1
- Trap220
- Trip2
- Usf
- Usf1
- Usf2
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|
Nectin/Necl trans heterodimerization
|
|
|
- Cadm1
- Cadm3
- D7Ertd458e
- Hvec
- Igsf4
- Igsf4b
- Lnir
- Mph
- Necl1
- Necl2
- Nectin1
- Nectin2
- Nectin3
- Nectin4
- Prr1
- Prr4
- Pvr
- Pvrl1
- Pvrl2
- Pvrl3
- Pvrl4
- Pvs
- Ra175
- SynCam1
- Syncam
- Syncam3
- Tage4
- Tslc1
- Tsll1
|
|
DSCAM interactions
|
|
|
|
|
Ligand-receptor interactions
|
|
|
- Cdo
- Cdon
- Dhh
- Gas-1
- Gas1
- Hhg1
- Hhip
- Hip
- Ihh
- Ptch
- Ptch1
- Shh
|
|
DCC mediated attractive signaling
|
|
|
- Cdc42
- Dcc
- Dock1
- Fyn
- Nck1
- Rac1
- Src
- Trio
|
|
G beta:gamma signalling through CDC42
|
|
|
- Arhgef6
- Cdc42
- Gnb1
- Gnb2
- Gnb3
- Gnb4
- Gnb5
- Gng1
- Gng10
- Gng11
- Gng12
- Gng13
- Gng2
- Gng3
- Gng4
- Gng5
- Gng7
- Gng8
- Gng9
- Gngt1
- Gngt11
- Gngt2
- Gngt3
- Gngt4
- Gngt5
- Gngt7
- Gngt8
- Gngt9
- Pak1
- Paka
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|
RHO GTPases activate KTN1
|
|
|
- Arha
- Arha2
- Arhg
- Cdc42
- Khcs
- Kiaa4086
- Kif5
- Kif5a
- Kif5b
- Klc1
- Klc2
- Klc3
- Klc4
- Kns1
- Kns2
- Knsl8
- Ktn1
- Nkhc1
- Rac1
- Rhoa
- Rhog
- Sid10750
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|
CD28 dependent Vav1 pathway
|
|
|
- B7
- Cd28
- Cd80
- Cd86
- Cdc42
- Fyn
- Lck
- Lsk-t
- Pak-3
- Pak1
- Pak2
- Pak3
- Paka
- Pakb
- Rac1
- Stk4
- Vav
- Vav1
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Activation of the pre-replicative complex
|
|
|
- Bm28
- Cdc21
- Cdc45
- Cdc45l
- Cdc45l2
- Cdc46
- Cdc47
- Cdc6
- Cdc7
- Cdc7l1
- Cdcl1
- Cdk2
- Cdkn2
- Cdt1
- Dbf4
- Dbf4a
- Gmnn
- Kiaa0030
- Mcm10
- Mcm2
- Mcm3
- Mcm4
- Mcm5
- Mcm6
- Mcm7
- Mcm8
- Mcmd
- Mcmd2
- Mcmd3
- Mcmd4
- Mcmd5
- Mcmd6
- Mcmd7
- Mis5
- Orc1
- Orc1l
- Orc2
- Orc2l
- Orc3
- Orc3l
- Orc4
- Orc4l
- Orc5
- Orc5l
- Orc6
- Orc6l
- Pola
- Pola1
- Pola2
- Pole
- Pole1
- Pole2
- Pole3
- Pole4
- Prim1
- Prim2
- Ris2
- Rpa1
- Rpa2
- Rpa3
- Rpa34
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|
SCF-beta-TrCP mediated degradation of Emi1
|
|
|
- Cdc20
- Cul1
- Emi1
- Fbxo5
- Fyr
- Fzr
- Fzr1
- Rps27a
- Skp1
- Skp1a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Phosphorylation of Emi1
|
|
|
- Ccn-2
- Ccnb1
- Ccnb1-rs13
- Cdc2
- Cdc20
- Cdc2a
- Cdk1
- Cdkn1
- Cycb
- Cycb1
- Emi1
- Fbxo5
- Fyr
- Fzr
- Fzr1
- Plk
- Plk1
|
|
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
|
|
|
|
|
Oncogene Induced Senescence
|
|
|
- Cdk4
- Cdk6
- Cdkn2b
- Cdkn6
- Crk2
- Crk3
- Erf
- Erk1
- Erk2
- Ets-1
- Ets1
- Ets2
- Id
- Id-1
- Id1
- Idb1
- Mapk
- Mapk1
- Mapk3
- Mdm2
- Mdm4
- Mdmx
- P53
- Prkm1
- Prkm3
- Rps27a
- Tp53
- Trp53
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
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|
Oxidative Stress Induced Senescence
|
|
|
- Ask1
- Cdk4
- Cdk6
- Cdkn2b
- Cdkn6
- Crk1
- Crk2
- Crk3
- Csbp1
- Csbp2
- D11Ertd530e
- Eed
- Enx1h
- Erk1
- Erk2
- Ezh2
- Fos
- Jmjd3
- Jnk1
- Jnk2
- Jnk3
- Jnkk1
- Jun
- Kdm6b
- Kiaa0160
- Kiaa0346
- Kiaa0551
- Map2k3
- Map2k4
- Map2k6
- Map2k7
- Map3k5
- Map4k4
- Map4k6
- Mapk
- Mapk1
- Mapk10
- Mapk11
- Mapk14
- Mapk3
- Mapk8
- Mapk9
- Mapkapk2
- Mapkapk3
- Mapkapk5
- Mdm2
- Mdm4
- Mdmx
- Mek4
- Mekk5
- Mink
- Mink1
- Mkk3
- Mkk4
- Mkk7
- Nik
- P53
- Prkm1
- Prkm10
- Prkm11
- Prkm3
- Prkm8
- Prkm9
- Prkmk3
- Prkmk4
- Prkmk6
- Rbap46
- Rbap48
- Rbbp4
- Rbbp7
- Rps27a
- Rps6kc1
- Sapkk3
- Sek1
- Serk1
- Serk2
- Skk1
- Suz12
- Tnik
- Tp53
- Trp53
- Txn
- Txn1
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
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|
PI5P Regulates TP53 Acetylation
|
|
|
- Ep300
- Ing1l
- Ing2
- Map2k6
- P300
- P53
- Pi5p4ka
- Pin1
- Pip4k2a
- Pip4k2b
- Pip4k2c
- Pip4p1
- Pip5k2a
- Pip5k2b
- Pip5k2c
- Prkmk6
- Sapkk3
- Tmem55b
- Tp53
- Trp53
|
|
Regulation of TP53 Activity through Methylation
|
|
|
- Atm
- Bat8
- Chek2
- Chk2
- Ehmt1
- Ehmt2
- Ep300
- Euhmtase1
- G9a
- Glp
- Jbp1
- Jmy
- Kiaa0681
- Kmt1d
- Kmt5a
- L3mbt
- L3mbtl
- L3mbtl1
- Mdm2
- Mdm4
- Mdmx
- Ng36
- P300
- P53
- Prmt5
- Rad53
- Rps27a
- Setd8
- Skb1
- Smyd2
- Strap
- Tp53
- Trp53
- Ttc5
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Stabilization of p53
|
|
|
- Atm
- Chek2
- Chk2
- Hca58
- Mdm2
- Mdm4
- Mdmx
- P53
- Phf20
- Rad53
- Rps27a
- Tp53
- Trp53
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
RUNX3 regulates CDKN1A transcription
|
|
|
- Aml2
- Atbf1
- Cbfa3
- Dpc4
- Madh3
- Madh4
- P53
- Pebp2a3
- Runx3
- Smad3
- Smad4
- Tgfb1
- Tp53
- Trp53
- Zfhx3
|
|
Transcriptional activation of cell cycle inhibitor p21
|
|
|
- Hzf
- P53
- Tp53
- Trp53
- Zfp385a
- Znf385a
|
|
Regulation of TP53 Expression
|
|
|
|
|
Deposition of new CENPA-containing nucleosomes at the centromere
|
|
|
- Apitd1
- Cenpa
- Cenpc
- Cenpc1
- Cenph
- Cenpi
- Cenpk
- Cenpl
- Cenpm
- Cenpn
- Cenpo
- Cenpp
- Cenpq
- Cenpr
- Cenps
- Cenpt
- Cenpu
- Cenpw
- Cenpx
- Cug2
- Enp
- FAAP16
- Faap10
- Fleg1
- Fshprh1
- Gm14920
- H2a.x
- H2ab1
- H2ab2
- H2ab3
- H2ac11
- H2ac12
- H2ac13
- H2ac15
- H2ac20
- H2ac4
- H2ac6
- H2ac8
- H2afv
- H2afx
- H2aj
- H2av
- H2ax
- H2az2
- H2b-f
- H2b-j
- H2b-l
- H2b-n
- H2bc1
- H2bc11
- H2bc12
- H2bc13
- H2bc14
- H2bc15
- H2bc21
- H2bc26
- H2bc26-ps
- H2bc3
- H2bc4
- H2bc6
- H2bc7
- H2bc8
- H2bc9
- H2bu1
- H2bu1-ps
- H4-12
- H4-53
- H4c1
- H4c11
- H4c12
- H4c14
- H4c16
- H4c2
- H4c3
- H4c4
- H4c6
- H4c8
- H4c9
- H4f16
- Hist1h2ab
- Hist1h2ac
- Hist1h2ae
- Hist1h2af
- Hist1h2ag
- Hist1h2ah
- Hist1h2ai
- Hist1h2ak
- Hist1h2an
- Hist1h2ao
- Hist1h2ap
- Hist1h2ba
- Hist1h2bb
- Hist1h2bc
- Hist1h2be
- Hist1h2bf
- Hist1h2bg
- Hist1h2bh
- Hist1h2bj
- Hist1h2bk
- Hist1h2bl
- Hist1h2bm
- Hist1h2bn
- Hist1h2bp
- Hist1h4a
- Hist1h4b
- Hist1h4c
- Hist1h4d
- Hist1h4f
- Hist1h4h
- Hist1h4i
- Hist1h4j
- Hist1h4k
- Hist1h4m
- Hist2h2aa1
- Hist2h2aa2
- Hist2h2ab
- Hist2h2ac
- Hist2h2be
- Hist2h4
- Hist2h4a
- Hist3h2bb
- Hist3h2bb-ps
- Hist4h4
- Hist5-2ax
- Hjurp
- Itgb3bp
- Kiaa1903
- Knl2
- M18bp1
- MHF1
- Mcm21r
- Mhf2
- Mis18a
- Mis18bp1
- Mlf1ip
- Ms18b
- Npm1
- Nrif3
- Oip5
- Pane1
- Rbap46
- Rbap48
- Rbbp4
- Rbbp7
- Rsf1
- Ruvbl1
- Smarca5
- Snf2h
- Solt
- Stra13
- Th2b
- Tip49
- Tip49a
|
|
Kinesins
|
|
|
- Atsv
- Cenpe
- Gm1305
- Khcs
- Kiaa1236
- Kiaa1590
- Kiaa1708
- Kiaa4086
- Kif1
- Kif11
- Kif12
- Kif13b
- Kif15
- Kif16b
- Kif18a
- Kif18b
- Kif19
- Kif19a
- Kif1a
- Kif1b
- Kif1c
- Kif2
- Kif20a
- Kif20b
- Kif21a
- Kif21b
- Kif22
- Kif23
- Kif26a
- Kif26b
- Kif27
- Kif28
- Kif28p
- Kif2a
- Kif2b
- Kif2c
- Kif3
- Kif3a
- Kif3b
- Kif3c
- Kif4
- Kif4a
- Kif5
- Kif5a
- Kif5b
- Kif6
- Kif9
- Kifap3
- Kifc1
- Kifc2
- Kifc4
- Kifc5a
- Kifc5b
- Klc1
- Klc2
- Klc3
- Klc4
- Klp2
- Klp6
- Kns1
- Kns2
- Kns4
- Knsl7
- Knsl8
- Mgcracgap
- Mphosph1
- Nkhc1
- Rab6kifl
- Racgap1
|
|
Endosomal Sorting Complex Required For Transport (ESCRT)
|
|
|
- Chmp2a
- Chmp2b
- Chmp3
- Chmp4b
- Chmp4c
- Chmp5
- Chmp6
- Chmp7
- D11Moh34
- D11Wsu68e
- Fam125a
- Fam125b
- Hbp
- Hgs
- Hrs
- Mvb12a
- Mvb12b
- Rps27a
- Skd1
- Snf7dc2
- Snf8
- Stam
- Stam1
- Stam2
- Tsg101
- Uba52
- Uba80
- Ubap1
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Vps24
- Vps25
- Vps28
- Vps36
- Vps37a
- Vps37b
- Vps37c
- Vps37d
- Vps4a
- Vps4b
- Vta1
- Wbscr24
|
|