Synthesis of active ubiquitin: roles of E1 and E2 enzymes
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- A1S9T
- CDC34
- CDC34B
- DFFRX
- E2EPF
- FAM
- FAM105B
- HAUSP
- HIP2
- ISOT
- LIG
- MOP4
- OTULIN
- PUBC1
- RAD6A
- RAD6B
- RPS27A
- SFT
- UBA1
- UBA52
- UBA6
- UBA80
- UBB
- UBC
- UBC16
- UBC3B
- UBC4
- UBC5A
- UBC5B
- UBC7
- UBCE4
- UBCE7
- UBCEP1
- UBCEP2
- UBCH1
- UBCH10
- UBCH3
- UBCH4
- UBCH5
- UBCH5A
- UBCH5B
- UBCH6
- UBCH7
- UBCH9
- UBE1
- UBE1L2
- UBE2A
- UBE2B
- UBE2C
- UBE2D1
- UBE2D2
- UBE2E1
- UBE2E3
- UBE2G
- UBE2G1
- UBE2G2
- UBE2H
- UBE2K
- UBE2L3
- UBE2Q2
- UBE2R1
- UBE2R2
- UBE2S
- UBE2T
- UBE2W
- UBE2Z
- UCHL3
- USP5
- USP7
- USP9
- USP9X
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Transport and synthesis of PAPS
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- ATPSK1
- ATPSK2
- C6orf196
- DTD
- DTDST
- PAPSS
- PAPSS1
- PAPSS2
- PAPST1
- PAPST2
- SAT1
- SLC26A1
- SLC26A2
- SLC35B2
- SLC35B3
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Neurofascin interactions
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- ANK
- ANK1
- CASPR
- CNTN1
- CNTNAP1
- DBCN
- DCX
- KIAA0343
- KIAA0756
- LISX
- MDA9
- NFASC
- NRCAM
- NRXN4
- SDCBP
- SYCL
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RNA Polymerase I Promoter Escape
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- CDK-activating kinase assembly factor MAT1
- Chromobox protein homolog 3
- Cyclin-H
- Cyclin-dependent kinase 7
- DNA-directed RNA polymerase I subunit RPA12
- DNA-directed RNA polymerase I subunit RPA1
- DNA-directed RNA polymerase I subunit RPA2
- DNA-directed RNA polymerase I subunit RPA34
- DNA-directed RNA polymerase I subunit RPA43
- DNA-directed RNA polymerase I subunit RPA49
- DNA-directed RNA polymerases I and III subunit RPAC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit 2
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 4
- General transcription factor IIH subunit 5
- Histone H2A type 1-B/E
- Histone H2A type 1-C
- Histone H2A type 1-D
- Histone H2A type 1-J
- Histone H2A type 2-A
- Histone H2A type 2-C
- Histone H2A-Bbd type 1
- Histone H2A.J
- Histone H2A.V
- Histone H2AX
- Histone H2B type 1-A
- Histone H2B type 1-B
- Histone H2B type 1-C/E/F/G/I
- Histone H2B type 1-D
- Histone H2B type 1-H
- Histone H2B type 1-J
- Histone H2B type 1-K
- Histone H2B type 1-L
- Histone H2B type 1-M
- Histone H2B type 1-N
- Histone H2B type 1-O
- Histone H2B type 2-E
- Histone H2B type 3-B
- Histone H2B type F-S
- Histone H3.1
- Histone H3.2
- Histone H3.3
- Histone H4
- Nucleolar transcription factor 1
- Protein POLR1D, isoform 2
- RNA polymerase I-specific transcription initiation factor RRN3
- TATA box-binding protein-associated factor RNA polymerase I subunit A
- TATA box-binding protein-associated factor RNA polymerase I subunit B
- TATA box-binding protein-associated factor RNA polymerase I subunit C
- TATA box-binding protein-associated factor RNA polymerase I subunit D
- TATA-box-binding protein
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- ASE1
- BTF2
- BTF2P44
- C6orf175
- CAK
- CAK1
- CAP35
- CAST
- CBX3
- CCNH
- CD3EAP
- CDK7
- CDKN7
- ERCC2
- ERCC3
- GTF2D1
- GTF2H1
- GTF2H2
- GTF2H3
- GTF2H4
- GTF2H5
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST4H4
- JOSD3
- MAT1
- MNAT1
- MO15
- PAF49
- PAF53
- POLR1A
- POLR1B
- POLR1C
- POLR1D
- POLR1E
- POLR1F
- POLR1G
- POLR1H
- POLR2E
- POLR2F
- POLR2H
- POLR2K
- POLR2L
- POLRF
- PRAF1
- RNF66
- RPA12
- RRN3
- STK1
- TAF1A
- TAF1B
- TAF1C
- TAF1D
- TBP
- TF2D
- TFIID
- TIFIA
- TSH2B
- TTDA
- TWISTNB
- UBF
- UBF1
- UBTF
- XPB
- XPBC
- XPD
- XPDC
- ZNRD1
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Regulation of Apoptosis
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IkBA variant leads to EDA-ID
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- CHUK
- FIP3
- IKBA
- IKBKB
- IKBKG
- IKKA
- IKKB
- LYT10
- MAD3
- NEMO
- NFKB1
- NFKB2
- NFKB3
- NFKBI
- NFKBIA
- RELA
- TCF16
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Defective ABCC2 causes DJS
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- ABCC2
- CMOAT
- CMOAT1
- CMRP
- MRP2
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Type II Na+/Pi cotransporters
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- NPT2
- NPT2C
- NPTIIC
- SLC17A2
- SLC34A1
- SLC34A2
- SLC34A3
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Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)
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Synthesis of Ketone Bodies
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- AACS
- ACAT
- ACAT1
- ACSF1
- ACSS3
- BDH
- BDH1
- BDH2
- DHRS6
- HMGCL
- HMGCLL1
- HMGCS2
- MAT
- SDR15C1
- SDR9C1
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SARS-CoV-2 targets host intracellular signalling and regulatory pathways
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- 3a
- AKT1
- AKT2
- AKT3
- CAV
- CAV1
- HME1
- M
- N
- PDK1
- PDPK1
- PKB
- PKBG
- RAC
- SFN
- YWHA1
- YWHAB
- YWHAE
- YWHAG
- YWHAH
- YWHAQ
- YWHAZ
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Pyrophosphate hydrolysis
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RHO GTPases activate PAKs
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- CALM
- CALM1
- CAM
- CAM1
- CDC42
- CTTN
- EMS1
- FLN
- FLN1
- FLNA
- KIAA0866
- KIAA2034
- LIMK
- LIMK1
- MBS
- MLC2
- MLCK
- MLCK1
- MRLC1
- MRLC2
- MYH10
- MYH11
- MYH14
- MYH9
- MYL12B
- MYL6
- MYL9
- MYLC2B
- MYLK
- MYLK1
- MYPT1
- MYPT2
- MYRL2
- NF2
- OPHN3
- PAK1
- PAK2
- PAK3
- PPP1CB
- PPP1R12A
- PPP1R12B
- RAC1
- SCH
- TC25
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Zygotic genome activation (ZGA)
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- CBP
- CREBBP
- DPPA2
- DPPA4
- DUX10
- DUX4
- DUXA
- DUXB
- EP300
- HS2
- KDM4DL
- KDM4E
- KIAA0191
- KIAA1711
- LEUTX
- P300
- P53
- PESCRG1
- RTEF1
- TCF13L1
- TEAD4
- TEF3
- TP53
- TPRX1
- TPRX2
- TPRXL
- TUT4
- TUT7
- YAP1
- YAP65
- ZCCHC11
- ZCCHC6
- ZNF494
- ZSCAN4
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Transport of fatty acids
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- ACSVL2
- ACSVL4
- ACSVL5
- APOD
- FACVL2
- FATP1
- FATP4
- FATP6
- LCN1
- LCN12
- LCN15
- LCN9
- SLC27A1
- SLC27A4
- SLC27A6
- VEGP
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Regulation of gene expression by Hypoxia-inducible Factor
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- ARNT
- BHLHE2
- BHLHE73
- BHLHE78
- CA9
- CBP
- CITED2
- CREBBP
- EP300
- EPAS1
- EPO
- G250
- HIF1A
- HIF2A
- HIG1
- HIGD1A
- MN
- MOP1
- MOP2
- MRG1
- P300
- PASD2
- PASD8
- VEGF
- VEGFA
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RAS processing
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- ABHD17A
- ABHD17B
- ABHD17C
- APT1
- ARL2
- BCL2L
- BCL2L1
- BCLX
- C19orf27
- C9orf77
- CALM
- CALM1
- CAM
- CAM1
- CXorf11
- DUB3
- FACE2
- FAM108A1
- FAM108B1
- FAM108C1
- FNTA
- FNTB
- GCP16
- GOLGA7
- HRAS
- HRAS1
- ICMT
- KRAS
- KRAS2
- LPL1
- LYPLA1
- NRAS
- PCCMT
- PDE6D
- PDED
- PRKCQ
- PRKCT
- PRKG2
- PRKGR2
- RASK2
- RCE1
- RCE1A
- RCE1B
- USP17
- USP17H
- USP17I
- USP17J
- USP17K
- USP17L
- USP17L2
- USP17M
- ZDHHC10
- ZDHHC9
- ZNF379
- ZNF380
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Sorafenib-resistant PDGFR mutants
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Ribavirin ADME
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- ADA
- ADA1
- ADK
- C20orf37
- CNT2
- CNT3
- ENT1
- ENT3
- ITPA
- NDPKA
- NM23
- NM23B
- NME1
- NME2
- NP
- NT5B
- NT5C2
- NT5CP
- PNP
- PNT5
- SLC28A2
- SLC28A3
- SLC29A1
- SLC29A3
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Nuclear Receptor transcription pathway
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- AD4BP
- AR
- ARC205
- BCON3
- CRSP1
- CRSP200
- CTG26
- DHTR
- DRIP205
- DRIP230
- EAR1
- EAR2
- EAR3
- EAR7
- ERBA1
- ERBA2
- ERBAL2
- ERBAL3
- ERR1
- ERR3
- ERRB2
- ERRG2
- ESR
- ESR1
- ESR2
- ESRL1
- ESRL2
- ESRRA
- ESRRB
- ESRRG
- ESTRB
- FTZF1
- GFRP1
- HAP
- HMR
- HNF4
- HNF4A
- HNF4G
- HREV
- KIAA0832
- KIAA1047
- LXRB
- MED1
- NAK1
- NCOR1
- NCOR2
- NER
- NOT
- NR0B2
- NR1A1
- NR1A2
- NR1B1
- NR1B2
- NR1B3
- NR1C1
- NR1C2
- NR1C3
- NR1D1
- NR1D2
- NR1F1
- NR1F2
- NR1F3
- NR1H2
- NR1I1
- NR2A1
- NR2A2
- NR2B1
- NR2B2
- NR2B3
- NR2C1
- NR2C2
- NR2C2AP
- NR2E1
- NR2F1
- NR2F6
- NR3A1
- NR3A2
- NR3B1
- NR3B2
- NR3B3
- NR3C3
- NR3C4
- NR4A1
- NR4A2
- NR5A1
- NRBP
- NRBP1
- NURR1
- PBP
- PGR
- PPAR
- PPARA
- PPARB
- PPARBP
- PPARD
- PPARG
- PPARGBP
- RARA
- RARB
- RARG
- RB18A
- RORA
- RORB
- RORC
- RORG
- RXRA
- RXRB
- RXRG
- RZRA
- RZRB
- RZRG
- SF1
- SHP
- TAK1
- TCF14
- TFCOUP1
- THR1
- THRA
- THRA1
- THRA2
- THRAL
- THRB
- TINUR
- TLX
- TR2
- TR4
- TRA16
- TRAP220
- TRIP2
- UNR
- VDR
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Nuclear signaling by ERBB4
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- AD3
- AD4
- ADAM17
- ADAP1
- APH1A
- APH1B
- APOE
- BHLHC12
- BTC
- C1orf215
- CASB
- CENTA1
- CSN2
- CSVP
- CXCL12
- DTR
- DTS
- EREG
- ESR
- ESR1
- FOR
- GFAP
- GGF
- HBEGF
- HEGFL
- HGL
- HRGA
- KIAA0253
- KIAA0733
- KIAA1047
- LAP18
- MAD4
- MAP3K7IP2
- MXD4
- NCOR1
- NCSTN
- NDF
- NR3A1
- NR3C3
- NRG1
- NRG2
- NRG3
- NRG4
- NTAK
- ON
- OP18
- PEN2
- PGR
- PS1
- PS2
- PSEN1
- PSEN2
- PSENEN
- PSF
- PSFL
- PSNL1
- PSNL2
- S100B
- SDF1
- SDF1A
- SDF1B
- SDR41C1
- SMDF
- SPARC
- SRC
- SRC1
- STAT5
- STAT5A
- STM2
- STMN1
- TAB2
- TACE
- WOX1
- WWOX
- YAP1
- YAP65
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Defective SLC2A9 causes hypouricemia renal 2 (RHUC2)
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Negative regulation of TCF-dependent signaling by WNT ligand antagonists
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- DKK1
- DKK2
- DKK4
- FRP
- FRP1
- FRP2
- KREMEN
- KREMEN1
- KREMEN2
- KRM1
- KRM2
- LR3
- LRP5
- LRP6
- LRP7
- SARP1
- SARP2
- SFRP1
- SFRP2
- SOST
- WIF1
- WNT14
- WNT3A
- WNT4
- WNT5A
- WNT9A
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PI-3K cascade:FGFR1
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- FGF1
- FGF10
- FGF2
- FGF20
- FGF22
- FGF23
- FGF3
- FGF4
- FGF6
- FGF9
- FGFA
- FGFB
- FRS2
- GAB1
- GRB1
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- INT2
- KS3
- PIK3CA
- PIK3R1
- PTP2C
- PTPN11
- SHPTP2
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Olfactory Signaling Pathway
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- ADCY3
- ANO2
- C12orf3
- C14orf13
- CNCA
- CNCA1
- CNCG2
- CNGA2
- CNGA4
- GNAL
- GNB1
- GNG13
- GPR164
- KIAA0511
- OLF3
- OLFR1
- OLFRA03
- OR10A6
- OR10G3
- OR10G4
- OR10G7
- OR10H2
- OR10H5
- OR10J5
- OR10S1
- OR10X1
- OR10X1P
- OR11A1
- OR11A2
- OR11H4
- OR11H6
- OR13C3
- OR14A2
- OR14J1
- OR1A1
- OR1C1
- OR1D2
- OR1D5
- OR1E1
- OR1E5
- OR1E6
- OR1E9P
- OR1N2
- OR2A1
- OR2A25
- OR2A25P
- OR2A27
- OR2A42
- OR2A7
- OR2AT4
- OR2B11
- OR2C1
- OR2C2P
- OR2F1
- OR2F3
- OR2F3P
- OR2F4
- OR2F5
- OR2J1
- OR2J1P
- OR2J2
- OR2J3
- OR2L13
- OR2L14
- OR2M2
- OR2M7
- OR2S2
- OR2T1
- OR2T4
- OR2W1
- OR2W3
- OR2W3P
- OR2W8P
- OR3A1
- OR4C12
- OR4D2
- OR4F11P
- OR4F17
- OR4F18
- OR4F19
- OR4L1
- OR4L2P
- OR4Q3
- OR4Q4
- OR51B5
- OR51D1
- OR51E1
- OR51E1P
- OR51E2
- OR51L1
- OR52A3P
- OR52B6
- OR56A4
- OR5AL1
- OR5AL1P
- OR5AX1
- OR5AX1P
- OR5D14
- OR5K1
- OR5P3
- OR5U1
- OR6F1
- OR6P1
- OR7C1
- OR7C4
- OR7D4
- OR7D4P
- OR7G2
- OR8B3
- OR8D1
- OR8D3
- OR8K3
- OR8U8
- OR9G1
- OR9G5
- POGR
- PSGR
- PSGR2
- TMEM16B
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