GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **551 - 575** of **2074** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
IRE1alpha activates chaperones	Endoplasmic reticulum chaperone BiP Serine/threonine-protein kinase/endoribonuclease IRE1	O75460 P11021	ERN1 GRP78 HSPA5 IRE1	Homo sapiens (human)
NEIL3-mediated resolution of ICLs	Endonuclease 8-like 3	Q8TAT5	NEIL3	Homo sapiens (human)
Defective Base Excision Repair Associated with NEIL3	Endonuclease 8-like 3	Q8TAT5	NEIL3	Homo sapiens (human)
SARS-CoV-2 modulates autophagy	Elongation factor Tu, mitochondrial Membrane protein Microtubule-associated proteins 1A/1B light chain 3B ORF3a protein ORF7a protein UV radiation resistance-associated gene protein Vacuolar protein sorting-associated protein 11 homolog Vacuolar protein sorting-associated protein 16 homolog Vacuolar protein sorting-associated protein 18 homolog Vacuolar protein sorting-associated protein 33A Vacuolar protein sorting-associated protein 33B Vacuolar protein sorting-associated protein 41 homolog Vacuolar protein sorting-associated protein 45 Vam6/Vps39-like protein	P0DTC3 P0DTC5 P0DTC7 P49411 P49754 Q96AX1 Q96JC1 Q9GZQ8 Q9H267 Q9H269 Q9H270 Q9NRW7 Q9P253 Q9P2Y5	3a 7a KIAA0770 KIAA1475 M MAP1ALC3 MAP1LC3B RNF108 TLP TUFM UVRAG VAM6 VPS11 VPS16 VPS18 VPS33A VPS33B VPS39 VPS41 VPS45 VPS45A VPS45B	Homo sapiens (human)
SARS-CoV-1 modulates host translation machinery	Elongation factor 1-alpha 1 Heterogeneous nuclear ribonucleoprotein A1 Nucleoprotein Replicase polyprotein 1a Replicase polyprotein 1ab Ribosomal protein eS27-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P08708 P08865 P09651 P0C6U8 P0C6X7 P15880 P22090 P23396 P25398 P39019 P42677 P46781 P46782 P46783 P59595 P60866 P61247 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62701 P62753 P62841 P62847 P62851 P62854 P62857 P62861 P62979 P63220 P68104 Q71UM5 Q8TD47	1a CCG2 D6S218E EEF1A EEF1A1 EF1A FAU FTE1 HNRNPA1 HNRPA1 LAMBR LAMR1 LENG7 MFTL MPS1 N RIG RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA SCAR UBA80 UBCEP1 rep	Homo sapiens (human)
Peptide chain elongation	Elongation factor 1-alpha 1 Elongation factor 2 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P05386 P05387 P05388 P08708 P08865 P13639 P15880 P18077 P18124 P18621 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P39019 P39023 P40429 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P50914 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P68104 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q6P5R6 Q71UM5 Q8TD47 Q92901 Q969Q0 Q96EH5 Q96L21 Q9UNX3 Q9Y3U8	BBC1 CCG2 D11S2243E D6S218E DXS648E EC45 EEF1A EEF1A1 EEF2 EF1A EF2 FAU FTE1 LAMBR LAMR1 LENG7 MFTL MPS1 NEDD6 QM RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SURF-3 SURF3 TXREB1 UBA52 UBA80 UBCEP1 UBCEP2	Homo sapiens (human)
Eukaryotic Translation Elongation	Elongation factor 1-alpha 1 Elongation factor 1-alpha 2 Elongation factor 1-beta Elongation factor 1-delta Elongation factor 1-gamma Putative elongation factor 1-alpha-like 3	P24534 P26641 P29692 P68104 Q05639 Q5VTE0	EEF1A EEF1A1 EEF1A1P5 EEF1A2 EEF1AL EEF1AL3 EEF1B EEF1B2 EEF1D EEF1G EF1A EF1B EF1D EF1G LENG7 STN	Homo sapiens (human)
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)	Electrogenic sodium bicarbonate cotransporter 1	Q9Y6R1	NBC NBC1 NBCE1 SLC4A4	Homo sapiens (human)
Elastic fibre formation	Elastin Fibrillin-1 Fibrillin-2 Fibrillin-3 Fibulin-5 Furin Integrin alpha-5 Integrin alpha-V Integrin beta-1 Integrin beta-3 Integrin beta-6 Lysyl oxidase homolog 1 Lysyl oxidase homolog 2 Lysyl oxidase homolog 3 Lysyl oxidase homolog 4 Microfibrillar-associated protein 2 Microfibrillar-associated protein 5 Protein-lysine 6-oxidase	P05106 P05556 P06756 P08648 P09958 P15502 P18564 P28300 P35555 P35556 P55001 P58215 Q08397 Q13361 Q75N90 Q96JB6 Q9UBX5 Q9Y4K0	DANCE ELN FBLN5 FBN FBN1 FBN2 FBN3 FNRA FNRB FUR FURIN GP3A ITGA5 ITGAV ITGB1 ITGB3 ITGB6 KIAA1776 LOX LOXC LOXL LOXL1 LOXL2 LOXL3 LOXL4 MAGP1 MAGP2 MDF2 MFAP2 MFAP5 MSK12 MSK8 PACE PCSK3 VNRA VTNR	Homo sapiens (human)
Vitamin B2 (riboflavin) metabolism	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 FAD synthase Riboflavin kinase Solute carrier family 52, riboflavin transporter, member 1 Solute carrier family 52, riboflavin transporter, member 2 Solute carrier family 52, riboflavin transporter, member 3 Tartrate-resistant acid phosphatase type 5	P13686 P22413 Q8NFF5 Q969G6 Q9HAB3 Q9NQ40 Q9NWF4	ACP5 C20orf54 ENPP1 FLAD1 GPR172A GPR172B M6S1 NPPS PAR1 PAR2 PC1 PDNP1 RFK RFT1 RFT2 RFT3 RFVT3 SLC52A1 SLC52A2 SLC52A3	Homo sapiens (human)
Phosphate bond hydrolysis by NTPDase proteins	Ectonucleoside triphosphate diphosphohydrolase 1 Ectonucleoside triphosphate diphosphohydrolase 2 Ectonucleoside triphosphate diphosphohydrolase 3 Ectonucleoside triphosphate diphosphohydrolase 4 Ectonucleoside triphosphate diphosphohydrolase 6 Ectonucleoside triphosphate diphosphohydrolase 7 Ectonucleoside triphosphate diphosphohydrolase 8 Nucleoside diphosphate phosphatase ENTPD5	O75354 O75355 O75356 P49961 Q5MY95 Q9NQZ7 Q9Y227 Q9Y5L3	CD39 CD39L1 CD39L2 CD39L3 CD39L4 ENTPD1 ENTPD2 ENTPD3 ENTPD4 ENTPD5 ENTPD6 ENTPD7 ENTPD8 IL6ST2 KIAA0392 LALP1 LALP70 LYSAL1 PCPH	Homo sapiens (human)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphoinositide 3-kinase regulatory subunit 4 Rabenosyn-5 Toll-like receptor 9	Q15075 Q8NEB9 Q99570 Q9H1K0 Q9NR96	EEA1 PIK3C3 PIK3R4 RBSN TLR9 VPS15 VPS34 ZFYVE2 ZFYVE20	Homo sapiens (human)
ERK/MAPK targets	ETS domain-containing protein Elk-1 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Myocyte-specific enhancer factor 2A Myocyte-specific enhancer factor 2C Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-5 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O75582 P19419 P27361 P28482 P30153 P30154 P51812 P62714 P67775 Q02078 Q06413 Q13164 Q14738 Q15349 Q15418 Q15759 Q16539	BMK1 CSBP CSBP1 CSBP2 CSPB1 ELK1 ERK1 ERK2 ERK5 ISPK1 MAPK1 MAPK11 MAPK14 MAPK3 MAPK7 MAPKAPK1A MAPKAPK1B MAPKAPK1C MEF2 MEF2A MEF2C MSK1 MXI2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKM1 PRKM11 PRKM2 PRKM3 PRKM7 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA5 RSK1 RSK2 RSK3 SAPK2 SAPK2A SAPK2B	Homo sapiens (human)
Inhibition of membrane repair	ESAT-6-like protein EsxG ESAT-6-like protein EsxH Hepatocyte growth factor-regulated tyrosine kinase substrate	O14964 O53692 P9WNK3	HGS HRS cfp7 esxG esxH	Homo sapiens (human)
IRAK1 recruits IKK complex	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
Signaling by RNF43 mutants	E3 ubiquitin-protein ligase RNF43 Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-8 Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Protein Wnt-3a	O60353 O75197 O75581 P56704 Q13467 Q68DV7 Q9H461 Q9ULV1	C2orf31 FZD4 FZD5 FZD6 FZD8 LR3 LRP5 LRP6 LRP7 RNF43 WNT3A	Homo sapiens (human)
Regulation of FZD by ubiquitination	E3 ubiquitin-protein ligase RNF43 E3 ubiquitin-protein ligase ZNRF3 Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-8 Leucine-rich repeat-containing G-protein coupled receptor 4 Leucine-rich repeat-containing G-protein coupled receptor 5 Leucine-rich repeat-containing G-protein coupled receptor 6 Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Polyubiquitin-B Polyubiquitin-C Protein Wnt-3a R-spondin-1 R-spondin-2 R-spondin-3 R-spondin-4 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60353 O75197 O75473 O75581 P0CG47 P0CG48 P40818 P56704 P62979 P62987 Q13467 Q2I0M5 Q2MKA7 Q68DV7 Q6UXX9 Q9BXB1 Q9BXY4 Q9H461 Q9HBX8 Q9ULT6 Q9ULV1	C20orf182 C2orf31 FZD4 FZD5 FZD6 FZD8 GPR48 GPR49 GPR67 KIAA0055 KIAA1133 LGR4 LGR5 LGR6 LR3 LRP5 LRP6 LRP7 PWTSR RNF203 RNF43 RPS27A RSPO1 RSPO2 RSPO3 RSPO4 THSD2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBPY USP8 WNT3A ZNRF3	Homo sapiens (human)
Downregulation of ERBB2:ERBB3 signaling	E3 ubiquitin-protein ligase NRDP1 Polyubiquitin-B Polyubiquitin-C Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Receptor tyrosine-protein kinase erbB-2 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14511 P04626 P0CG47 P0CG48 P31749 P31751 P40818 P62979 P62987 Q02297 Q9H4P4 Q9Y243	AKT1 AKT2 AKT3 ERBB2 FLRF GGF HER2 HGL HRGA KIAA0055 MLN19 NDF NEU NGL NRDP1 NRG1 NRG2 NTAK PKB PKBG RAC RNF41 RPS27A SMDF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBPY USP8	Homo sapiens (human)
Myoclonic epilepsy of Lafora	E3 ubiquitin-protein ligase NHLRC1 Glycogen [starch] synthase, muscle Glycogenin-1 Laforin Polyubiquitin-B Polyubiquitin-C Protein phosphatase 1 regulatory subunit 3C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O95278 P0CG47 P0CG48 P13807 P46976 P62979 P62987 Q6VVB1 Q9UQK1	EPM2A EPM2B GYG GYG1 GYS GYS1 NHLRC1 PPP1R3C PPP1R5 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Regulation of PTEN localization	E3 ubiquitin-protein ligase NEDD4 E3 ubiquitin-protein ligase XIAP Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Polyubiquitin-B Polyubiquitin-C Protein PML Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P29590 P46934 P60484 P62979 P62987 P98170 Q93009	API3 BIRC4 HAUSP IAP3 KIAA0093 MMAC1 MYL NEDD4 NEDD4-1 PML PP8675 PTEN RNF71 RPF1 RPS27A TEP1 TRIM19 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 XIAP	Homo sapiens (human)
LXRs regulate gene expression to limit cholesterol uptake	E3 ubiquitin-protein ligase MYLIP Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta	P19793 P28702 P55055 Q13133 Q8WY64	BZF1 IDOL LXRA LXRB MYLIP NER NR1H2 NR1H3 NR2B1 NR2B2 RXRA RXRB UNR	Homo sapiens (human)
Downregulation of ERBB4 signaling	E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase NEDD4 NEDD4-like E3 ubiquitin-protein ligase WWP1 Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P12931 P46934 P62979 P62987 Q96J02 Q9H0M0	ITCH KIAA0093 NEDD4 NEDD4-1 RPF1 RPS27A SRC SRC1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWP1	Homo sapiens (human)
IRF3 mediated activation of type 1 IFN	E3 ubiquitin-protein ligase DTX4 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 Serine/threonine-protein kinase TBK1 Z-DNA-binding protein 1	Q14653 Q96MN2 Q9H171 Q9UHD2 Q9Y2E6	C20orf183 DLM1 DTX4 IRF3 KIAA0937 NAK NALP4 NLRP4 PAN2 PYPAF4 RNF155 RNH2 TBK1 ZBP1	Homo sapiens (human)
Regulation of innate immune responses to cytosolic DNA	E3 ubiquitin-protein ligase DTX4 E3 ubiquitin-protein ligase TRIM21 E3 ubiquitin-protein ligase TRIM32 E3 ubiquitin-protein ligase TRIM56 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 Polyubiquitin-B Polyubiquitin-C Probable ATP-dependent RNA helicase DDX41 Serine/threonine-protein kinase TBK1 Stimulator of interferon genes protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Z-DNA-binding protein 1	P0CG47 P0CG48 P19474 P62979 P62987 Q13049 Q14653 Q86WV6 Q96MN2 Q9BRZ2 Q9H171 Q9UHD2 Q9UJV9 Q9Y2E6	ABS C20orf183 DDX41 DLM1 DTX4 ERIS HT2A IRF3 KIAA0937 MITA NAK NALP4 NLRP4 PAN2 PYPAF4 RNF109 RNF155 RNF81 RNH2 RO52 RPS27A SSA1 STING STING1 TBK1 TMEM173 TRIM21 TRIM32 TRIM56 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZBP1	Homo sapiens (human)

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