GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1951 - 1975** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Complex I biogenesis	Acyl carrier protein, mitochondrial Arginine-hydroxylase NDUFAF5, mitochondrial Complex I assembly factor ACAD9, mitochondrial Complex I assembly factor TIMMDC1, mitochondrial Complex I assembly factor TMEM126B, mitochondrial Complex I intermediate-associated protein 30, mitochondrial Cytochrome c oxidase assembly factor 1 homolog Distal membrane-arm assembly complex protein 1 Distal membrane-arm assembly complex protein 2 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial FAD-dependent oxidoreductase domain-containing protein 1 Iron-sulfur cluster co-chaperone protein HscB Iron-sulfur cluster transfer protein NUBPL LYR motif-containing protein 2 Mitochondrial inner membrane protein OXA1L NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 Protein arginine methyltransferase NDUFAF7, mitochondrial Protein preY, mitochondrial Sideroflexin-4 Stress-70 protein, mitochondrial Transmembrane protein 126A Transmembrane protein 186	A1L188 O00217 O14561 O15239 O43181 O43674 O43676 O43677 O43678 O43920 O75251 O75306 O75380 O75438 O75489 O95139 O95167 O95168 O95169 O95178 O95182 O95298 O95299 O96000 P03886 P03891 P03897 P03905 P03915 P03923 P17568 P19404 P28331 P38646 P49821 P51970 P56181 P56556 Q15070 Q16718 Q16795 Q330K2 Q5TEU4 Q6P4A7 Q7L592 Q86Y39 Q8IUX1 Q8IWL3 Q8N183 Q8TB37 Q96B77 Q96CU9 Q96GE9 Q96I23 Q9BQ95 Q9BU61 Q9GZY4 Q9H061 Q9H845 Q9NPL8 Q9NU23 Q9NW81 Q9NX14 Q9P032 Q9P0J0 Q9UI09 Q9Y375 Q9Y6M9	ACAD9 ATP5SL BCRM1 C14orf127 C16orf51 C17orf89 C20orf7 C2orf56 C3orf1 C3orf60 C6orf66 C7orf44 C8orf38 C9orf123 CIA30 COA1 DAP13 DMAC1 DMAC2 DNAJC20 ECSIT FOXRED1 GRIM19 GRP75 HRPAP20 HSC20 HSCB HSPA9 HSPA9B LYRM2 LYRM3 LYRM6 MITRAC15 MT-ND1 MT-ND2 MT-ND3 MT-ND4 MT-ND5 MT-ND6 MTND1 MTND2 MTND3 MTND4 MTND5 MTND6 NADH1 NADH2 NADH3 NADH4 NADH5 NADH6 NADHB14 ND1 ND2 ND3 ND4 ND5 ND6 NDUFA1 NDUFA10 NDUFA11 NDUFA12 NDUFA12L NDUFA13 NDUFA2 NDUFA3 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFAF1 NDUFAF2 NDUFAF3 NDUFAF4 NDUFAF5 NDUFAF6 NDUFAF7 NDUFAF8 NDUFAFQ NDUFB1 NDUFB10 NDUFB11 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS2L NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 NUBPL OXA1L PREY PYURF SFXN4 TIMMDC1 TMEM126A TMEM126B TMEM186 TMEM261 UQOR1 UQOR22 mt-HSP70	Homo sapiens (human)
Reactions specific to the hybrid N-glycan synthesis pathway	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Q09327	GGNT3 MGAT3	Homo sapiens (human)
Release of Hh-Np from the secreting cell	Desert hedgehog protein Disintegrin and metalloproteinase domain-containing protein 17 Glypican-5 Indian hedgehog protein Palmitoleoyl-protein carboxylesterase NOTUM Protein dispatched homolog 2 Signal peptide, CUB and EGF-like domain-containing protein 2 Sonic hedgehog protein	A7MBM2 O43323 P78333 P78536 Q14623 Q15465 Q6P988 Q9NQ36	ADAM17 C15orf36 CEGP1 CSVP DHH DISP2 DISPB GPC5 IHH KIAA1742 LINC00594 NOTUM SCUBE2 SHH TACE	Homo sapiens (human)
Tie2 Signaling	Angiopoietin-1 receptor Angiopoietin-1 Angiopoietin-2 Angiopoietin-4 Docking protein 2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 14 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform SHC-transforming protein 1 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O00459 O15123 O60496 P01111 P01112 P27986 P29353 P42336 P42338 Q02763 Q06124 Q07889 Q14449 Q14451 Q15389 Q9Y264	ANG3 ANG4 ANGPT1 ANGPT2 ANGPT4 DOK2 GRB1 GRB14 GRB7 HRAS HRAS1 KIAA0003 NRAS PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PTP2C PTPN11 SHC SHC1 SHCA SHPTP2 SOS1 TEK TIE2 VMCM VMCM1	Homo sapiens (human)
Ligand-receptor interactions	Brother of CDO Cell adhesion molecule-related/down-regulated by oncogenes Desert hedgehog protein Growth arrest-specific protein 1 Hedgehog-interacting protein Indian hedgehog protein Protein patched homolog 1 Sonic hedgehog protein	O43323 P54826 Q13635 Q14623 Q15465 Q4KMG0 Q96QV1 Q9BWV1	BOC CDO CDON DHH GAS1 HHIP HIP IHH PTCH PTCH1 SHH	Homo sapiens (human)
Reelin signalling pathway	Disabled homolog 1 Reelin SH3 domain-containing kinase-binding protein 1 Tyrosine-protein kinase Fyn Very low-density lipoprotein receptor	O75553 P06241 P78509 P98155 Q96B97	CIN85 DAB1 FYN RELN SH3KBP1 VLDLR	Homo sapiens (human)
RUNX3 regulates RUNX1-mediated transcription	Core-binding factor subunit beta Runt-related transcription factor 3	Q13761 Q13951	AML2 CBFA3 CBFB PEBP2A3 RUNX3	Homo sapiens (human)
Defective ABCA3 causes SMDP3	Phospholipid-transporting ATPase ABCA3	Q99758	ABC3 ABCA3	Homo sapiens (human)
FOXO-mediated transcription of cell cycle genes	Caveolin-1 Cyclin-G2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Forkhead box protein G1 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Growth arrest and DNA damage-inducible protein GADD45 alpha Growth/differentiation factor 8 Krueppel-like factor 4 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Poly(rC)-binding protein 4 Protein BTG1 Retinoblastoma-like protein 2	O14793 O43474 O43524 P24522 P38936 P46527 P55316 P57723 P62324 P84022 P98177 Q03135 Q08999 Q12778 Q13485 Q15796 Q16589	AFX AFX1 BTG1 CAP20 CAV CAV1 CCNG2 CDKN1 CDKN1A CDKN1B CIP1 DDIT1 DPC4 EZF FKH2 FKHL1 FKHL2 FKHL3 FKHL4 FKHR FKHRL1 FOXG1 FOXG1A FOXG1B FOXG1C FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 GADD45 GADD45A GDF8 GKLF KIP1 KLF4 MADH2 MADH3 MADH4 MADR2 MDA6 MLLT7 MSTN PCBP4 PIC1 RB2 RBL2 SDI1 SMAD2 SMAD3 SMAD4 WAF1 p27	Homo sapiens (human)
ABC transporters in lipid homeostasis	ATP-binding cassette sub-family A member 10 ATP-binding cassette sub-family A member 2 ATP-binding cassette sub-family A member 6 ATP-binding cassette sub-family A member 9 ATP-binding cassette sub-family D member 1 ATP-binding cassette sub-family D member 2 ATP-binding cassette sub-family D member 3 ATP-binding cassette sub-family G member 1 ATP-binding cassette sub-family G member 4 ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8 Apolipoprotein A-I Cholesterol transporter ABCA5 Glucosylceramide transporter ABCA12 Peroxisomal biogenesis factor 19 Peroxisomal biogenesis factor 3 Phospholipid-transporting ATPase ABCA3 Phospholipid-transporting ATPase ABCA7	P02647 P28288 P33897 P40855 P45844 P56589 Q86UK0 Q8IUA7 Q8IZY2 Q8N139 Q8WWZ4 Q8WWZ7 Q99758 Q9BZC7 Q9H172 Q9H221 Q9H222 Q9UBJ2	ABC12 ABC2 ABC3 ABC8 ABCA10 ABCA12 ABCA2 ABCA3 ABCA5 ABCA6 ABCA7 ABCA9 ABCD1 ABCD2 ABCD3 ABCG1 ABCG4 ABCG5 ABCG8 ALD ALD1 ALDL1 ALDR ALDRP APOA1 HK33 KIAA1062 KIAA1888 PEX19 PEX3 PMP70 PXF PXMP1 WHITE2 WHT1	Homo sapiens (human)
Formation of definitive endoderm	C-X-C chemokine receptor type 4 Cadherin-1 Catenin beta-1 Eomesodermin homolog Hepatocyte nuclear factor 3-beta Homeobox protein MIXL1 Homeobox protein goosecoid Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 T-box transcription factor T Transcription factor 7-like 2 Transcription factor GATA-4 Transcription factor GATA-6 Transcription factor SOX-17	O15178 O95936 P12830 P35222 P43694 P56915 P61073 P84022 Q13485 Q15796 Q92908 Q9H2W2 Q9H6I2 Q9NQB0 Q9Y261	CDH1 CDHE CTNNB CTNNB1 CXCR4 DPC4 EOMES FOXA2 GATA4 GATA6 GSC HNF3B MADH2 MADH3 MADH4 MADR2 MIXL MIXL1 SMAD2 SMAD3 SMAD4 SOX17 T TBR2 TBXT TCF3B TCF4 TCF7L2 UVO	Homo sapiens (human)
MET activates PI3K/AKT signaling	GRB2-associated-binding protein 1 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	P08581 P14210 P27986 P42336 Q13480	GAB1 GRB1 HGF HPTA MET PIK3CA PIK3R1	Homo sapiens (human)
Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)	Basigin Monocarboxylate transporter 1	P35613 P53985	BSG MCT1 SLC16A1	Homo sapiens (human)
Cytosolic iron-sulfur cluster assembly	Anamorsin Cytosolic Fe-S cluster assembly factor NUBP1 Cytosolic Fe-S cluster assembly factor NUBP2 Cytosolic iron-sulfur assembly component 2B Cytosolic iron-sulfur assembly component 3 DNA polymerase delta catalytic subunit Fanconi anemia group J protein General transcription and DNA repair factor IIH helicase subunit XPD Iron-sulfur clusters transporter ABCB7, mitochondrial MMS19 nucleotide excision repair protein homolog NADPH-dependent diflavin oxidoreductase 1 Probable cytosolic iron-sulfur protein assembly protein CIAO1 Regulator of telomere elongation helicase 1	O75027 O76071 P18074 P28340 P53384 Q6FI81 Q96T76 Q9BX63 Q9H6Q4 Q9NZ71 Q9UHB4 Q9Y3D0 Q9Y5Y2	ABC7 ABCB7 BACH1 BRIP1 C20orf41 CIA1 CIAB CIAO1 CIAO2B CIAO3 CIAPIN1 ERCC2 FAM96B FANCJ KIAA1088 MIP18 MMS19 MMS19L NARFL NBP NBP1 NDOR1 NHL NR1 NUBP1 NUBP2 POLD POLD1 PRN RTEL1 WDR39 XPD XPDC	Homo sapiens (human)
alpha-linolenic acid (ALA) metabolism	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Acyl-coenzyme A thioesterase 8 Long-chain-fatty-acid--CoA ligase 1 Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O14734 O60427 O95864 P09110 P22307 P33121 P33897 P51659 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACAA ACAA1 ACOT8 ACSL1 ACTEIII ALD CIG30 EDH17B4 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 HSD17B4 LACS LACS1 LACS2 PTE1 PTHIO SCP2 SDR8C1 SSC1 SSC2	Homo sapiens (human)
RHOH GTPase cycle	Caveolin-1 Drebrin Junction plakoglobin Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methionine synthase NSFL1 cofactor p47 Neutral amino acid transporter B(0) Oxysterol-binding protein-related protein 11 Protein FAM91A1 Protein NipSnap homolog 2 Ragulator complex protein LAMTOR1 Ral GTPase-activating protein subunit alpha-1 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GDP-dissociation inhibitor 3 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoH Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase PAK 5 Serine/threonine-protein kinase PAK 6 Sodium bicarbonate cotransporter 3 Stomatin Transferrin receptor protein 1 Transitional endoplasmic reticulum ATPase Transmembrane protein 59 Tubulin alpha-1B chain Tyrosine-protein kinase CSK Tyrosine-protein kinase Lck Tyrosine-protein kinase ZAP-70 Uveal autoantigen with coiled-coil domains and ankyrin repeats Vang-like protein 1 Vesicle-associated membrane protein 3 WD repeat-containing protein 11	O75116 O75323 O96013 P02786 P06239 P11182 P14923 P27105 P41240 P43403 P51149 P52565 P52566 P55072 P68363 Q03135 Q13153 Q13177 Q13464 Q15669 Q15758 Q15836 Q16643 Q658Y4 Q6GYQ0 Q6IAA8 Q8TAA9 Q99707 Q99819 Q9BXB4 Q9BXS4 Q9BZF9 Q9BZH6 Q9NQU5 Q9P286 Q9UNZ2 Q9Y6M7	ARHGDIA ARHGDIB ARHGDIG ARHH ASCT2 BCATE2 BCKDHE2 BND7 BRWD2 BT C11orf59 C1orf8 CAV CAV1 CSK CTNNG D0S117E DBN1 DBT DP3 EPB72 FAM91A1 GARNL1 GBAS GDIA1 GDIA2 GDID4 HEL-220 HEL-S-70 JUP KIAA0619 KIAA0884 KIAA1142 KIAA1264 KIAA1351 KIAA1561 LAMTOR1 LCK M7V1 MTR NBC2 NBC2B NBC3 NBCn1 NIPSNAP2 NSFL1C ORP11 OSBP12 OSBPL11 PAK1 PAK2 PAK4 PAK5 PAK6 PAK7 PDRO RAB7 RAB7A RALGAPA1 RAP1GN1 RDR RDRC RHOH ROCK1 ROCK2 SBC2 SLC1A5 SLC4A6 SLC4A7 SRK STB2 STOM SYB3 TFRC TMEM59 TTF TUBA1B TULIP1 UACA UBXN2C VAMP3 VANGL1 VCP WDR11 WDR15 ZAP70	Homo sapiens (human)
Regulation of CDH11 function	Angiopoietin-related protein 4 Cadherin-11 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Disintegrin and metalloproteinase domain-containing protein 19 Disintegrin and metalloproteinase domain-containing protein 33 Junction plakoglobin	O60716 P14923 P35221 P35222 P55287 Q9BY76 Q9BZ11 Q9H013	ADAM19 ADAM33 ANGPTL4 ARP4 C20orf153 CDH11 CTNNA1 CTNNB CTNNB1 CTNND1 CTNNG DP3 HFARP JUP KIAA0384 MLTNB PGAR	Homo sapiens (human)
Cellular response to mitochondrial stress	ATP-dependent zinc metalloprotease YME1L1 DAP3-binding cell death enhancer 1 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 2-alpha kinase 1 Metalloendopeptidase OMA1, mitochondrial Prohibitin-2 Stomatin-like protein 2, mitochondrial	P05198 P20042 P41091 Q14154 Q96E52 Q96TA2 Q99623 Q9BQI3 Q9UJZ1	BAP DELE DELE1 EIF2A EIF2AK1 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 FTSH1 HRI KIAA0141 KIAA1369 MPRP1 OMA1 PHB2 REA SLP2 STOML2 YME1L YME1L1	Homo sapiens (human)
Inhibition of nitric oxide production	Importin subunit alpha-5 Importin subunit beta-1 Nitric oxide synthase, inducible PPE family protein PPE2	P35228 P52294 P9WI47 Q14974	KPNA1 KPNB1 NOS2 NOS2A NTF97 PPE2 RCH2	Homo sapiens (human)
Recycling of eIF2:GDP	Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Translation initiation factor eIF2B subunit alpha Translation initiation factor eIF2B subunit beta Translation initiation factor eIF2B subunit delta Translation initiation factor eIF2B subunit epsilon Translation initiation factor eIF2B subunit gamma	P05198 P20042 P41091 P49770 Q13144 Q14232 Q9NR50 Q9UI10	EIF2A EIF2B EIF2B1 EIF2B2 EIF2B3 EIF2B4 EIF2B5 EIF2BA EIF2BB EIF2BD EIF2BE EIF2G EIF2S1 EIF2S2 EIF2S3	Homo sapiens (human)
TBC/RABGAPs	ADP-ribosylation factor 6 ADP-ribosylation factor-binding protein GGA1 ADP-ribosylation factor-binding protein GGA2 ADP-ribosylation factor-binding protein GGA3 Carabin Gamma-aminobutyric acid receptor-associated protein-like 2 Gamma-aminobutyric acid receptor-associated protein Genome polyprotein Hamartin Microtubule-associated proteins 1A/1B light chain 3B Optineurin Rab GTPase-activating protein 1 Rab GTPase-binding effector protein 1 Rab5 GDP/GTP exchange factor Ras-related protein Rab-11A Ras-related protein Rab-11B Ras-related protein Rab-33A Ras-related protein Rab-33B Ras-related protein Rab-35 Ras-related protein Rab-4A Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-7a Ras-related protein Rab-7b Ras-related protein Rab-8A Ras-related protein Rab-8B Serine/threonine-protein kinase ULK1 Synaptotagmin-like protein 1 TBC1 domain family member 10A TBC1 domain family member 10B TBC1 domain family member 13 TBC1 domain family member 14 TBC1 domain family member 15 TBC1 domain family member 16 TBC1 domain family member 17 TBC1 domain family member 20 TBC1 domain family member 24 TBC1 domain family member 25 TBC1 domain family member 2A TBC1 domain family member 3 TBC1 domain family member 7 Tuberin	O75385 O95166 P20338 P20339 P20340 P27958 P49815 P51148 P51149 P60520 P61006 P61020 P62330 P62491 Q14088 Q15276 Q15286 Q15907 Q3MII6 Q4KMP7 Q8IV04 Q8IYJ3 Q8IZP1 Q8TBP0 Q8TC07 Q92574 Q92930 Q96AH8 Q96BZ9 Q96CV9 Q9BXI6 Q9BYX2 Q9GZQ8 Q9H082 Q9HA65 Q9NRW1 Q9NVG8 Q9NZ52 Q9P0N9 Q9P2M4 Q9UJ41 Q9UJY4 Q9UJY5 Q9ULP9 Q9Y3P9	ARF6 C20orf140 EPI64 FIP2 FLC3A FLC3B GABARAP GABARAPL2 GEF2 GGA1 GGA2 GGA3 GLC1E HIP7 HYPL KIAA0154 KIAA0243 KIAA0722 KIAA1080 KIAA1171 KIAA1322 MAP1ALC3 MAP1LC3B MEL NRP OATL1 OPTN PARIS1 PP8997 PRC17 RAB11 RAB11A RAB11B RAB1C RAB33A RAB33B RAB35 RAB4 RAB4A RAB5 RAB5A RAB5B RAB5C RAB5EP RAB6 RAB6A RAB6B RAB7 RAB7A RAB7B RAB8 RAB8A RAB8B RABEP1 RABEX5 RABGAP1 RABGEF1 RABL RABPT5 RABPT5A RABS10 RAY SLP1 SYTL1 TBC1D10 TBC1D10A TBC1D10B TBC1D10C TBC1D13 TBC1D14 TBC1D15 TBC1D16 TBC1D17 TBC1D2 TBC1D20 TBC1D24 TBC1D25 TBC1D2A TBC1D3 TBC1D3A TBC1D7 TBC7 TSC TSC1 TSC2 TSC4 ULK1 YPT3	Homo sapiens (human)
CDH11 homotypic and heterotypic interactions	Cadherin-11 Cadherin-24 Cadherin-8 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Junction plakoglobin	O60716 P14923 P35221 P35222 P55286 P55287 Q86UP0	CDH11 CDH11L CDH24 CDH8 CTNNA1 CTNNB CTNNB1 CTNND1 CTNNG DP3 JUP KIAA0384	Homo sapiens (human)
Regulation of PLK1 Activity at G2/M Transition	14-3-3 protein epsilon 14-3-3 protein gamma A-kinase anchor protein 9 Alpha-centractin Aurora kinase A CDK5 regulatory subunit-associated protein 2 CLIP-associating protein 1 Casein kinase I isoform delta Casein kinase I isoform epsilon Centrin-2 Centriolar coiled-coil protein of 110 kDa Centriole and centriolar satellite protein OFD1 Centriolin Centromere protein J Centrosomal protein 43 Centrosomal protein of 131 kDa Centrosomal protein of 135 kDa Centrosomal protein of 152 kDa Centrosomal protein of 164 kDa Centrosomal protein of 192 kDa Centrosomal protein of 290 kDa Centrosomal protein of 41 kDa Centrosomal protein of 57 kDa Centrosomal protein of 63 kDa Centrosomal protein of 70 kDa Centrosomal protein of 72 kDa Centrosomal protein of 76 kDa Centrosomal protein of 78 kDa Centrosome-associated protein ALMS1 Centrosome-associated protein CEP250 Cullin-1 Cyclin-dependent kinase 1 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoskeleton-associated protein 5 Dynactin subunit 2 Dynactin subunit 3 Dynein light chain 1, cytoplasmic F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 HAUS augmin-like complex subunit 1 HAUS augmin-like complex subunit 2 HAUS augmin-like complex subunit 3 HAUS augmin-like complex subunit 4 HAUS augmin-like complex subunit 5 HAUS augmin-like complex subunit 6 HAUS augmin-like complex subunit 7 HAUS augmin-like complex subunit 8 Heat shock protein HSP 90-alpha LIM domain-containing protein ajuba Microtubule nucleation factor SSNA1 Microtubule-associated protein RP/EB family member 1 Ninein-like protein Nuclear distribution protein nudE homolog 1 Optineurin Outer dense fiber protein 2 Pericentrin Pericentriolar material 1 protein Platelet-activating factor acetylhydrolase IB subunit beta Polyubiquitin-B Polyubiquitin-C Protein NEDD1 Protein SFI1 homolog Protein aurora borealis Protein phosphatase 1 regulatory subunit 12A Ras-related protein Rab-8A S-phase kinase-associated protein 1 Serine/threonine-protein kinase Nek2 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase PLK4 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serologically defined colon cancer antigen 8 Tubulin alpha-1A chain Tubulin alpha-4A chain Tubulin beta chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin gamma-1 chain Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type II-beta regulatory subunit	A8K8P3 O00444 O14965 O14974 O15078 O43303 O43805 O75665 O75935 O94927 O94986 O95067 O95613 O95684 P04350 P06493 P07437 P07900 P0CG47 P0CG48 P14635 P17612 P23258 P30153 P31323 P41208 P43034 P48730 P49674 P51955 P53350 P61006 P61163 P61981 P62140 P62258 P62979 P62987 P63167 P63208 P68366 P68371 Q13409 Q13561 Q13616 Q14008 Q14204 Q15154 Q15691 Q5BJF6 Q5JTW2 Q66GS9 Q68CZ6 Q6PGQ7 Q71U36 Q7Z460 Q7Z4H7 Q7Z7A1 Q86SQ7 Q86XR8 Q8NHQ1 Q8NHV4 Q8TAP6 Q8TCU4 Q8TEP8 Q96CS2 Q96CV9 Q96IF1 Q96MT8 Q96SN8 Q99871 Q99996 Q9BT25 Q9BV73 Q9BYV8 Q9H6D7 Q9HC77 Q9NVX0 Q9NXR1 Q9P209 Q9UKB1 Q9UPN4 Q9UPV0 Q9Y297 Q9Y2I6	ACTR1A AIK AIRK1 AJUBA AKAP350 AKAP450 AKAP9 ALMS1 ARK1 AURA AURKA AYK1 AZI1 BBS14 BITE BORA BTAK BTRC BTRCP BTRCP2 C13orf34 C14orf94 C15orf25 C18orf9 C4orf15 C9orf81 CALT CCCAP CCDC5 CCNB CCNB1 CCNB2 CCP110 CDC2 CDC28A CDK1 CDK5RAP2 CDKN1 CEN2 CENPJ CEP1 CEP110 CEP131 CEP135 CEP152 CEP164 CEP192 CEP2 CEP215 CEP250 CEP27 CEP290 CEP4 CEP41 CEP43 CEP57 CEP63 CEP70 CEP72 CEP76 CEP78 CETN2 CKAP5 CLASP1 CNAP1 CNTRL CP110 CPAP CSNK1D CSNK1E CTRN1 CUL1 CXorf5 DCTN2 DCTN22 DCTN3 DCTN50 DGT6 DHC1 DLC1 DNCH1 DNCI2 DNCIC2 DNCL DNCL1 DNCLC1 DNECL DYHC DYNC1H1 DYNC1I2 DYNLL1 EMC19 FAM29A FBW1A FBW1B FBXW11 FBXW1A FBXW1B FGFR1OP FIP2 FOP GLC1E HAUS1 HAUS2 HAUS3 HAUS4 HAUS5 HAUS6 HAUS7 HAUS8 HCKID HDLC1 HEIC HICE1 HIP7 HSP90A HSP90AA1 HSPC1 HSPCA HYPL IAK1 JUB KIAA0092 KIAA0097 KIAA0325 KIAA0328 KIAA0373 KIAA0402 KIAA0419 KIAA0542 KIAA0622 KIAA0635 KIAA0696 KIAA0803 KIAA0841 KIAA0912 KIAA0980 KIAA1052 KIAA1118 KIAA1519 KIAA1569 KIAA1574 KIAA1633 LAP LIP1 LIS1 MAPRE1 MAST1 MBS MDCR MDS MEL MYPT1 NA14 NDE1 NEDD1 NEK2 NEK2A NINL NLK1 NLP NPHP10 NPHP15 NPHP6 NRP NUDE OCP2 ODF2 OFD1 OPTN P34CDC2 PAFAH1B1 PAFAHA PCM1 PCNT PCNT2 PKACA PLK PLK1 PLK4 PPP1CB PPP1R12A PPP2R1A PRKACA PRKAR2B RAB8 RAB8A RPS27A SAK SDCCAG8 SFI1 SKP1 SKP1A SSNA1 STK15 STK18 STK6 TCEB1L TSGA14 TSP57 TUBA1 TUBA1A TUBA3 TUBA4A TUBB TUBB2C TUBB4 TUBB4A TUBB4B TUBB5 TUBG TUBG1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCHL5IP UIP1 YWHAE YWHAG	Homo sapiens (human)
TGFBR3 regulates activin signaling	Activin receptor type-2A Inhibin alpha chain Inhibin beta A chain Transforming growth factor beta receptor type 3	P05111 P08476 P27037 Q03167	ACVR2 ACVR2A INHA INHBA TGFBR3	Homo sapiens (human)
Regulated proteolysis of p75NTR	Disintegrin and metalloproteinase domain-containing protein 17 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Nicastrin Nuclear factor NF-kappa-B p105 subunit Presenilin-1 Presenilin-2 TNF receptor-associated factor 6 Transcription factor p65 Tumor necrosis factor receptor superfamily member 16	P08138 P19838 P49768 P49810 P78536 Q04206 Q8WW43 Q92542 Q96BI3 Q9NZ42 Q9Y4K3	AD3 AD4 ADAM17 APH1A APH1B CSVP KIAA0253 NCSTN NFKB1 NFKB3 NGFR PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RELA RNF85 STM2 TACE TNFRSF16 TRAF6	Homo sapiens (human)

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