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Standards Ontologies Notations
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 180 in total
Gene ID Gene Symbol Description Source
2 A2M alpha-2-macroglobulin
25 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
43 ACHE acetylcholinesterase (Yt blood group)
50 ACO2 aconitase 2
111 ADCY5 adenylate cyclase 5
131 ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
157 GRK3 G protein-coupled receptor kinase 3
185 AGTR1 angiotensin II receptor type 1
207 AKT1 AKT serine/threonine kinase 1
Displaying entries 1 - 10 of 146 in total
Gene ID Gene Symbol Description Source
11350 Abl1 c-abl oncogene 1, non-receptor tyrosine kinase
11423 Ache acetylcholinesterase
11529 Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
11607 Agtr1a angiotensin II receptor, type 1a
11608 Agtr1b angiotensin II receptor, type 1b
11651 Akt1 thymoma viral proto-oncogene 1
11652 Akt2 thymoma viral proto-oncogene 2
11747 Anxa5 annexin A5
12064 Bdnf brain derived neurotrophic factor
12317 Calr calreticulin
Displaying entries 41 - 50 of 82 in total
Gene ID Gene Symbol Description Source
29714 Ptprn2 protein tyrosine phosphatase, receptor type N2
54305 Sstr2 somatostatin receptor 2
60663 Insrr insulin receptor-related receptor
63868 Hspd1 heat shock protein family D (Hsp60) member 1
64347 Sncg synuclein, gamma
64532 Adcy5 adenylate cyclase 5
65248 Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1
79250 Aco2 aconitase 2
81528 Ogg1 8-oxoguanine DNA glycosylase
81638 Agtr1b angiotensin II receptor, type 1b
Displaying entries 11 - 20 of 25 in total
Gene ID Gene Symbol Description Source
37196 5-HT1A 5-hydroxytryptamine (serotonin) receptor 1A
37455 Egfr Epidermal growth factor receptor
38545 nAChRbeta1 nicotinic Acetylcholine Receptor beta1
39557 Hsp110 Heat shock protein 110
41166 Calr Calreticulin
41625 Ace Acetylcholine esterase
41726 Dop1R1 Dopamine 1-like receptor 1
41840 Hsc70-4 Heat shock protein 70 cognate 4
42490 Mvl Malvolio
42549 InR Insulin-like receptor
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 11 - 20 of 26 in total
Gene ID Gene Symbol Description Source
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177044 smf-3 NRAMP-like transporter smf-3
177314 gba-4 Putative glucosylceramidase 4
178535 gba-3 Putative glucosylceramidase 3
179347 dop-2 Dopamine receptor 2
180714 dop-1 Dopamine receptor 1
180747 glit-1 Neuroligin-like protein glit-1
180837 cat-1 Major facilitator superfamily (MFS) profile domain-containing protein
180937 acr-3 Acetylcholine receptor subunit beta-type acr-3
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
850370 PGK1 phosphoglycerate kinase
850721 SMF3 putative divalent metal ion transporter SMF3
851013 ACO1 aconitate hydratase ACO1
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852351 AKL1 serine/threonine protein kinase AKL1
852470 SMY2 Smy2p
852495 PGI1 glucose-6-phosphate isomerase
852806 HSF1 stress-responsive transcription factor HSF1
853071 TIF4631 translation initiation factor eIF4G
853300 YAK1 serine/threonine protein kinase YAK1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024