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Standards Ontologies Notations
asthma

Summary
Synonym
  • bronchial hyperreactivity
  • chronic obstructive asthma
  • chronic obstructive asthma with acute exacerbation
  • chronic obstructive asthma with status asthmaticus
Definition
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Super Class
bronchial disease
Disease Ontology
DOID:2841
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 151 - 160 of 206 in total
Gene ID Gene Symbol Description Source
6439 SFTPB surfactant protein B
6440 SFTPC surfactant protein C
6441 SFTPD surfactant protein D
6532 SLC6A4 solute carrier family 6 member 4
6572 SLC18A3 solute carrier family 18 member A3
6580 SLC22A1 solute carrier family 22 member 1
6648 SOD2 superoxide dismutase 2
6772 STAT1 signal transducer and activator of transcription 1
6775 STAT4 signal transducer and activator of transcription 4
6778 STAT6 signal transducer and activator of transcription 6
Displaying entries 111 - 120 of 191 in total
Gene ID Gene Symbol Description Source
18127 Nos3 nitric oxide synthase 3, endothelial cell
18205 Ntf3 neurotrophin 3
18211 Ntrk1 neurotrophic tyrosine kinase, receptor, type 1
18591 Pdgfb platelet derived growth factor, B polypeptide
18646 Prf1 perforin 1 (pore forming protein)
18654 Pgf placental growth factor
18669 Abcb1b ATP-binding cassette, sub-family B member 1B
18671 Abcb1a ATP-binding cassette, sub-family B member 1A
18783 Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent)
19074 Prg2 proteoglycan 2, bone marrow
Displaying entries 1 - 10 of 112 in total
Gene ID Gene Symbol Description Source
24180 Agtr1a angiotensin II receptor, type 1a
24182 Agtr2 angiotensin II receptor, type 2
24225 Bdnf brain-derived neurotrophic factor
24232 C3 complement C3
24255 Cftr CF transmembrane conductance regulator
24260 Chrm3 cholinergic receptor, muscarinic 3
24310 Ace angiotensin I converting enzyme
24464 Hp haptoglobin
24493 Il1a interleukin 1 alpha
24598 Nos1 nitric oxide synthase 1
Displaying entries 11 - 20 of 33 in total
Gene ID Gene Symbol Description Source
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
37455 Egfr Epidermal growth factor receptor
37892 mAChR-A muscarinic Acetylcholine Receptor, A-type
37895 SerT Serotonin transporter
38223 Cht2 Chitinase 2
38326 Pxn Peroxidasin
38726 Mdr65 Multi drug resistance 65
39015 TrpA1 Transient receptor potential cation channel A1
40404 ORMDL Orosomucoid 1-like
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
394082 slc18a3b solute carrier family 18 member 3b
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
436718 rhocb ras homolog family member Cb
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
399298 ntf3.L neurotrophin 3 L homeolog Xenopus laevis (African clawed frog)
495825 abo.3.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog Xenopus laevis (African clawed frog)
549437 abo.3 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 Xenopus tropicalis (tropical clawed frog)
549858 abo.2 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 Xenopus tropicalis (tropical clawed frog)
550054 abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
172841 45566 Organic cation transporter 1
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175383 zmp-2 Matrix metalloproteinase-B
175504 pat-3 Integrin beta pat-3
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
178118 trpa-1 Ion transport domain-containing protein;Transient receptor potential cation channel subfamily A member 1 homolog
178215 pgp-1 Multidrug resistance protein pgp-1
178274 cho-1 High-affinity choline transporter 1
Displaying all 8 entries
Gene ID Gene Symbol Description Source
850462 GIT1 Git1p
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
851977 CTS2 putative chitinase
853671 STE6 ATP-binding cassette a-factor transporter STE6
853978 NFT1 putative multidrug transporter NFT1
854394 STE13 Ste13p
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
856294 RHO1 Rho family GTPase RHO1
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
HP:0000006 Autosomal dominant inheritance
HP:0002099 Asthma
Displaying 1 entry
Gene ID Gene Symbol Description
240 ALOX5 arachidonate 5-lipoxygenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024