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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
colorectal cancer
Summary
- Definition
- A large intestine cancer that is located_in the colon and/or located_in the rectum.
- Super Class
- large intestine cancer
External Links
- Disease Ontology
- DOID:9256
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | |
| 102 | ADAM10 | ADAM metallopeptidase domain 10 | |
| 133 | ADM | adrenomedullin | |
| 207 | AKT1 | AKT serine/threonine kinase 1 | |
| 208 | AKT2 | AKT serine/threonine kinase 2 | |
| 324 | APC | APC regulator of WNT signaling pathway | |
| 329 | BIRC2 | baculoviral IAP repeat containing 2 | |
| 331 | XIAP | X-linked inhibitor of apoptosis | |
| 345 | APOC3 | apolipoprotein C3 | |
| 387 | RHOA | ras homolog family member A |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 21825 | Thbs1 | thrombospondin 1 | |
| 21929 | Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | |
| 21950 | Tnfsf9 | tumor necrosis factor (ligand) superfamily, member 9 | |
| 22059 | Trp53 | transformation related protein 53 | |
| 22139 | Ttr | transthyretin | |
| 22289 | Kdm6a | lysine (K)-specific demethylase 6A | |
| 22339 | Vegfa | vascular endothelial growth factor A | |
| 22601 | Yap1 | yes-associated protein 1 | |
| 22612 | Yes1 | YES proto-oncogene 1, Src family tyrosine kinase | |
| 24088 | Tlr2 | toll-like receptor 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 29650 | Adam10 | ADAM metallopeptidase domain 10 | |
| 50671 | Fasn | fatty acid synthase | |
| 50687 | L1cam | L1 cell adhesion molecule | |
| 56761 | Notch3 | notch receptor 3 | |
| 56820 | Ramp3 | receptor activity modifying protein 3 | |
| 58966 | Ramp2 | receptor activity modifying protein 2 | |
| 59086 | Tgfb1 | transforming growth factor, beta 1 | |
| 59323 | Erbb4 | erb-b2 receptor tyrosine kinase 4 | |
| 60628 | Cxcr4 | C-X-C motif chemokine receptor 4 | |
| 81686 | Mmp2 | matrix metallopeptidase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31293 | N | Notch | |
| 31792 | Nrg | Neuroglian | |
| 32556 | Stim | Stromal interaction molecule | |
| 33196 | smo | smoothened | |
| 33496 | lilli | lilliputian | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 35560 | Bap170 | Brahma associated protein 170kD | |
| 37455 | Egfr | Epidermal growth factor receptor | |
| 39392 | Est-6 | Esterase 6 | |
| 39393 | Est-P | Esterase P |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30225 | smo | smoothened, frizzled class receptor | |
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 30718 | notch1a | notch receptor 1a | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 559736 | galnt12 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373801 | tgfb2.L | transforming growth factor beta 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 379783 | akt2.L | v-akt murine thymoma viral oncogene homolog 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 380373 | cxcr4.S | C-X-C motif chemokine receptor 4 S homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 397787 | ttr.L | transthyretin L homeolog | Xenopus laevis (African clawed frog) | |
| 399170 | akt1.S | AKT serine/threonine kinase 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 399187 | adam10.S | ADAM metallopeptidase domain 10 S homeolog | Xenopus laevis (African clawed frog) | |
| 399347 | fgfr3.S | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog | Xenopus laevis (African clawed frog) | |
| 432172 | akt2.S | v-akt murine thymoma viral oncogene homolog 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 100037842 | notch1 | notch 1 receptor | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 172233 | unc-40 | Netrin receptor unc-40 | |
| 172689 | sup-17 | Disintegrin and metalloproteinase domain-containing protein 10 homolog | |
| 174044 | sma-6 | Serine/threonine-protein kinase receptor sma-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175182 | ver-1 | Protein ver-1 | |
| 175201 | stim-1 | Stromal interaction molecule 1 | |
| 175590 | cdh-4 | Cadherin-4 | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 176575 | plr-1 | putative E3 ubiquitin-protein ligase plr-1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0006716 | Hereditary nonpolyposis colorectal carcinoma |
| HP:0002891 | Uterine leiomyosarcoma |
| HP:0006753 | Neoplasm of the stomach |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0006740 | Transitional cell carcinoma of the bladder |
| HP:0005584 | Renal cell carcinoma |
