diabetes mellitus

Summary
Synonym
  • diabetes
Definition
A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
Super Class
glucose metabolism disease
Disease Ontology
DOID:9351
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 84 in total
Gene ID Gene Symbol Description Source
654 BMP6 bone morphogenetic protein 6
655 BMP7 bone morphogenetic protein 7
656 BMP8B bone morphogenetic protein 8b
959 CD40LG CD40 ligand
999 CDH1 cadherin 1
1080 CFTR CF transmembrane conductance regulator
1361 CPB2 carboxypeptidase B2
1436 CSF1R colony stimulating factor 1 receptor
1508 CTSB cathepsin B
1543 CYP1A1 cytochrome P450 family 1 subfamily A member 1
Displaying entries 31 - 40 of 72 in total
Gene ID Gene Symbol Description Source
15439 Hp haptoglobin
15894 Icam1 intercellular adhesion molecule 1
16001 Igf1r insulin-like growth factor I receptor
16153 Il10 interleukin 10
16184 Il2ra interleukin 2 receptor, alpha chain
16333 Ins1 insulin I
16334 Ins2 insulin II
16337 Insr insulin receptor
16398 Itga2 integrin alpha 2
16514 Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11
Displaying entries 1 - 10 of 46 in total
Gene ID Gene Symbol Description Source
24255 Cftr CF transmembrane conductance regulator
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24385 Gck glucokinase
24446 Hgf hepatocyte growth factor
24464 Hp haptoglobin
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24617 Serpine1 serpin family E member 1
Displaying entries 1 - 10 of 21 in total
Gene ID Gene Symbol Description Source
31234 Pdfr Pigment-dispersing factor receptor
31271 w white
32974 Zw Zwischenferment
34091 Spn28Dc Serpin 28Dc
35259 Lar Leukocyte-antigen-related-like
35486 sxc super sex combs
36692 scb scab
37455 Egfr Epidermal growth factor receptor
37778 gbb glass bottom boat
38109 Glut1 Glucose transporter 1
Displaying all 6 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
64274 csf1ra colony stimulating factor 1 receptor, a
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
322857 prom1a prominin 1a
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
559080 cftr CF transmembrane conductance regulator
Displaying all 8 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178748 zmp-3 Matrix metalloproteinase-C
179053 cpr-4 Cathepsin B-like cysteine proteinase 4
179197 cri-2 Putative metalloproteinase inhibitor tag-225
Displaying entries 11 - 14 of 14 in total
Gene ID Gene Symbol Description Source
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
855480 ZWF1 glucose-6-phosphate dehydrogenase
856014 GLR1 glutathione-disulfide reductase GLR1
856533 ECM14 putative metallocarboxypeptidase

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