obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Disease Ontology
DOID:9970
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
Related Genes
Displaying entries 211 - 220 of 343 in total
Gene ID Gene Symbol Description Source
6347 CCL2 C-C motif chemokine ligand 2
6352 CCL5 C-C motif chemokine ligand 5
6354 CCL7 C-C motif chemokine ligand 7
6382 SDC1 syndecan 1
6403 SELP selectin P
6439 SFTPB surfactant protein B
6513 SLC2A1 solute carrier family 2 member 1
6531 SLC6A3 solute carrier family 6 member 3
6550 SLC9A3 solute carrier family 9 member A3
6554 SLC10A1 solute carrier family 10 member 1
Displaying entries 181 - 190 of 241 in total
Gene ID Gene Symbol Description Source
30052 Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor
50490 Nox4 NADPH oxidase 4
50518 a nonagouti
50721 Sirt6 sirtuin 6
53322 Nucb2 nucleobindin 2
56373 Cpb2 carboxypeptidase B2
56643 Slc15a1 solute carrier family 15 (oligopeptide transporter), member 1
56717 Mtor mechanistic target of rapamycin kinase
56774 Slc6a14 solute carrier family 6 (neurotransmitter transporter), member 14
57738 Slc15a2 solute carrier family 15 (H+/peptide transporter), member 2
Displaying entries 1 - 10 of 151 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24217 Atp4b ATPase H+/K+ transporting subunit beta
24225 Bdnf brain-derived neurotrophic factor
24232 C3 complement C3
24267 Comt catechol-O-methyltransferase
24310 Ace angiotensin I converting enzyme
24318 Drd2 dopamine receptor D2
24367 Fgg fibrinogen gamma chain
24377 G6pd glucose-6-phosphate dehydrogenase
Displaying entries 41 - 43 of 43 in total
Gene ID Gene Symbol Description Source
43766 PlexB Plexin B
44643 Cnx99A Calnexin 99A
117364 Hex-t1 Hexokinase testis 1
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 51 in total
Gene ID Gene Symbol Description Source
171782 abt-2 ABC transporter domain-containing protein
171994 lin-44 Abnormal cell lineage protein 44
171999 poml-2 Arylesterase
173169 eif-6 Eukaryotic translation initiation factor 6
173399 cwn-1 Protein Wnt-1
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175201 stim-1 Stromal interaction molecule 1
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850442 SRB8 Srb8p
850614 HXK1 hexokinase 1
850647 PUF3 mRNA-binding protein PUF3
851241 CNE1 calnexin
851888 DPL1 sphinganine-1-phosphate aldolase DPL1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852053 SSN2 Ssn2p
852102 IZH1 PAQR-type receptor
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
9672 SDC3 syndecan 3

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Last updated: December 9, 2024