GlyCosmos Portal

Mus musculus (house mouse)

Summary

Taxonomy ID: 10090
PubChem Taxonomy: 10090

Genes (662) Glycans (1270) Glycoproteins (13000) Lectins (276) Pathways (1335)

Displaying entries **576 - 600** of **1335** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Presynaptic depolarization and calcium channel opening	Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent L-type calcium channel subunit beta-4 Voltage-dependent N-type calcium channel subunit alpha-1B Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2 Voltage-dependent calcium channel subunit alpha-2/delta-3	O55017 O88602 P54285 P97445 Q61290 Q6PHS9 Q8CC27 Q8R0S4 Q8R3Z5 Q9JJV4 Q9Z1L5	Caca1a Cach4 Cach5 Cach6 Cacn3 Cacna1a Cacna1b Cacna1e Cacna2d2 Cacna2d3 Cacnb1 Cacnb2 Cacnb3 Cacnb4 Cacng2 Cacng4 Cacnl1a4 Cacnl1a5 Cacnl1a6 Cacnlb1 Cacnlb2 Cacnlb3 Cacnlb4 Ccha1a Cchn1a Cchra1 Kiaa0558 Stg
p38MAPK events	GTPase HRas GTPase KRas GTPase NRas MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Ral guanine nucleotide dissociation stimulator	P08556 P32883 P47811 P49138 Q03385 Q3UMW7 Q61411 Q9WUI1	Crk1 Csbp1 Csbp2 Hras Hras1 Kras Kras2 Mapk11 Mapk14 Mapkapk2 Mapkapk3 Nras Prkm11 Ralgds Rgds Rps6kc1
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor	P18762 P25962 P30545 P34971 P97714 P97717 P97718 Q01337 Q01338	Adra1a Adra1b Adra1c Adra1d Adra2a Adra2b Adra2c Adrb1 Adrb1r Adrb2 Adrb2r Adrb3 Adrb3r B3bar Gpcr8
RAF activation	14-3-3 protein beta/alpha BRCA1-associated protein Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 GTPase HRas GTPase KRas GTPase NRas Kinase suppressor of Ras 1 Leucine-rich repeat protein SHOC-2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase kinase kinase 11 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras-related protein M-Ras Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Tyrosine-protein kinase JAK2	O08989 O88520 P04627 P05480 P08556 P0DP26 P11798 P28028 P28652 P31938 P32883 P62141 P62715 P63087 P63330 P67778 Q03141 Q60996 Q61097 Q61151 Q61411 Q62120 Q63932 Q6PD03 Q6PD28 Q6PHZ2 Q76MZ3 Q7TNL5 Q7TNP2 Q80XI6 Q923T9 Q99MP8 Q99N57 Q9CQV8	A-raf Araf Araf1 B-raf Braf Brap Calm Calm1 Cam Cam1 Camk2a Camk2b Camk2d Camk2g Craf Emk2 Hras Hras1 Jak2 Kiaa4006 Kiaa4163 Kras Kras2 Ksr Ksr1 Map2k1 Map2k2 Map3k11 Mark3 Mek1 Mek2 Mkk2 Mlk3 Mpk10 Mras Nras Phb Phb1 Ppp1cb Ppp1cc Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Prkmk1 Prkmk2 Raf1 Shoc2 Src Xras Ywhab
Oncogene Induced Senescence	Cellular tumor antigen p53 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 DNA-binding protein inhibitor ID-1 E3 ubiquitin-protein ligase Mdm2 ETS domain-containing transcription factor ERF Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Protein C-ets-1 Protein C-ets-2 Protein Mdm4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O35618 P02340 P0CG49 P0CG50 P15037 P20067 P23804 P27577 P30285 P55271 P62983 P62984 P63085 P70459 Q63844 Q64261	Cdk4 Cdk6 Cdkn2b Cdkn6 Crk2 Crk3 Erf Erk1 Erk2 Ets-1 Ets1 Ets2 Id Id-1 Id1 Idb1 Mapk Mapk1 Mapk3 Mdm2 Mdm4 Mdmx P53 Prkm1 Prkm3 Rps27a Tp53 Trp53 Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2
Pyroptosis	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Caspase-1 Caspase-3 Caspase-4 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cytochrome c, somatic Gasdermin-D Gasdermin-E Granzyme B(G,H) High mobility group protein B1 Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Neutrophil elastase	O08734 P01582 P04187 P0C0A3 P10749 P29452 P62897 P63158 P70343 P70380 P70677 Q07813 Q3UP87 Q8BJF9 Q8R1T1 Q9CQ10 Q9D7F7 Q9D8B3 Q9D8T2 Q9DB34 Q9Z2D3	Bak Bak1 Bax Casp1 Casp11 Casp3 Casp4 Caspl Chmp2a Chmp2b Chmp3 Chmp4b Chmp4c Chmp6 Chmp7 Cpp32 Ctla-1 Ctla1 Cycs Dfna5 Dfna5h Ela2 Elane Gsdmd Gsdmdc1 Gsdme Gzmb Hmg-1 Hmg1 Hmgb1 Ich3 Igif Il18 Il1a Il1b Il1bc Vps24
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Calcineurin subunit B type 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calmodulin-1 Catenin beta-1 Frizzled-2 Frizzled-3 Frizzled-4 Frizzled-5 Frizzled-6 GTPase KRas Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Lymphoid enhancer-binding factor 1 Mitogen-activated protein kinase kinase kinase 7 Nuclear factor of activated T-cells, cytoplasmic 1 Protein Wnt-11 Protein Wnt-5a Protein phosphatase 3 catalytic subunit alpha Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta Serine/threonine-protein kinase NLK Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform Transcription factor 7-like 2	A3KGF7 O54949 O88942 P09174 P0DP26 P11798 P18872 P22725 P23440 P27664 P27782 P29387 P32883 P48453 P48615 P50149 P50153 P51432 P61953 P62874 P62880 P62881 P63078 P63213 P63216 P63328 Q02248 Q61011 Q61012 Q61016 Q61017 Q61086 Q61088 Q61089 Q62073 Q63810 Q80SZ7 Q924A0 Q9CXP8 Q9DAS9 Q9EQD0 Q9JIP6 Q9JMF3 Q9Z1B3	Calm Calm1 Calna Calnb Cam Cam1 Camk2a Catnb Cnb Ctnnb1 Fzd10 Fzd2 Fzd3 Fzd4 Fzd5 Fzd6 Gna0 Gnao Gnao1 Gnat2 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng1 Gng10 Gng11 Gng12 Gng13 Gng2 Gng3 Gng4 Gng5 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt2 Gngt3 Gngt4 Gngt5 Gngt7 Gngt8 Gngt9 Kras Kras2 Lef1 Map3k7 Mpa Mpb Nfat2 Nfatc Nfatc1 Nlk Pde6a Pde6b Pde6g Pdea Pdeb Pdeg Plcb Plcb1 Plcb2 Plcb3 Ppp3ca Ppp3cb Ppp3r1 Tak1 Tcf4 Tcf7l2 Wnt-11 Wnt-5a Wnt11 Wnt5a rd
RNA Polymerase III Transcription Initiation From Type 2 Promoter	DNA-directed RNA polymerase III subunit RPC10 DNA-directed RNA polymerase III subunit RPC2 DNA-directed RNA polymerase III subunit RPC3 DNA-directed RNA polymerase III subunit RPC4 DNA-directed RNA polymerase III subunit RPC5 DNA-directed RNA polymerase III subunit RPC6 DNA-directed RNA polymerase III subunit RPC7-like DNA-directed RNA polymerase III subunit RPC7 DNA-directed RNA polymerase III subunit RPC8 DNA-directed RNA polymerase III subunit RPC9 DNA-directed RNA polymerase subunit DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor 3C polypeptide 1 General transcription factor 3C polypeptide 2 General transcription factor 3C polypeptide 4 General transcription factor 3C polypeptide 5 General transcription factor 3C polypeptide 6 General transcription factor IIIC, polypeptide 3 TATA-box-binding protein Transcription factor IIIB 90 kDa subunit Transcription factor TFIIIB component B'' homolog	B2RXC6 O35427 P29037 P52432 P59470 P61219 P62876 Q3TMP1 Q571C7 Q63871 Q6NXY9 Q80UW8 Q8BL74 Q8BMQ2 Q8CFK2 Q8K284 Q8R0C0 Q8R2T8 Q91WD1 Q921X6 Q923G2 Q9CQZ7 Q9CZT4 Q9D2C6 Q9D483 Q9D8P7	AL022818 Bdp1 Bn51t Brf1 Crcp Gtf3c1 Gtf3c2 Gtf3c3 Gtf3c4 Gtf3c5 Gtf3c6 Kiaa0011 Kiaa1241 Mt1a Polr1c Polr2e Polr2f Polr2h Polr2k Polr2l Polr3a Polr3b Polr3c Polr3d Polr3e Polr3f Polr3g Polr3gl Polr3h Polr3k Rpo1-1 Sin Tbp Tfiid Tfnr
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor IX Coagulation factor VII Coagulation factor X Tissue factor pathway inhibitor Tissue factor	O54819 O88947 P16294 P20352 P70375	Cf-3 Cf3 Cf7 Cf9 F10 F3 F7 F9 Tfpi
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon regulatory factor 7 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG49 P0CG50 P10810 P35235 P62983 P62984 P70347 P70434 P70671 Q60803 Q6PDS3 Q80UF7 Q8BJQ4 Q8K3K8 Q9JHF9 Q9QUK6 Q9R0T8 Q9WUN2	Cap-1 Cd14 Craf1 Esop1 Ikbke Ikke Ikki Irf3 Irf7 Itraf Kiaa0524 Lps Ly96 Md2 Optn Ptpn11 Rps27a Sarm1 Tank Tbk1 Ticam1 Ticam2 Tirp Tlr4 Traf3 Trafamn Tram Trif Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2
Thromboxane signalling through TP receptor	Angio-associated migratory protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-13 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Thromboxane A2 receptor	J3QN89 P21278 P21279 P27601 P29387 P30677 P30678 P30987 P50153 P61953 P62874 P62880 P62881 P63078 P63213 P63216 Q61011 Q61012 Q61016 Q61017 Q80SZ7 Q9CXP8 Q9DAS9 Q9JMF3	Aamp Gna-11 Gna-13 Gna-14 Gna-15 Gna11 Gna13 Gna14 Gna15 Gnaq Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng1 Gng10 Gng11 Gng12 Gng13 Gng2 Gng3 Gng4 Gng5 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt2 Gngt3 Gngt4 Gngt5 Gngt7 Gngt8 Gngt9 Tbxa2r
Toll Like Receptor 7/8 (TLR7/8) Cascade	Toll-like receptor 7	P58681	Tlr7
Assembly of the ORC complex at the origin of replication	Importin subunit alpha-5 Importin subunit alpha-7 Importin subunit beta-1 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6	O35345 O88708 P70168 Q60862 Q60960 Q9JK30 Q9WUJ8 Q9WUV0 Q9Z1N2	Impnb Kpna1 Kpna5 Kpna6 Kpnb1 Orc1 Orc1l Orc2 Orc2l Orc3 Orc3l Orc4 Orc4l Orc5 Orc5l Orc6 Orc6l Rch2
MET interacts with TNS proteins	Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta-1 Tensin-3 Tensin-4	P09055 P16056 Q08048 Q5SSZ5 Q8BZ33	Hgf Itgb1 Met Tens1 Tns3 Tns4
Threonine catabolism	2-iminobutanoate/2-iminopropanoate deaminase L-serine dehydratase/L-threonine deaminase Serine dehydratase-like	P52760 Q8R238 Q8VBT2	Hrp12 Rida Sds Sdsl
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O89110 P10810 Q60855 Q61160 Q80UF7 Q8BJQ4 Q9JHF9 Q9QUK6 Q9QZL0	Casp8 Cd14 Esop1 Fadd Lps Ly96 Md2 Mort1 Rinp Rip Rip3 Ripk1 Ripk3 Ticam1 Ticam2 Tirp Tlr4 Tram Trif
Interleukin-18 signaling	Interleukin-18 receptor 1 Interleukin-18 receptor accessory protein Interleukin-18-binding protein Interleukin-18	P70380 Q61098 Q9Z0M9 Q9Z2B1	Igif Igifbp Il18 Il18bp Il18r1 Il18rap
Multifunctional anion exchangers	Anion exchange transporter Chloride anion exchanger Pendrin Sodium-coupled monocarboxylate transporter 2 Sodium-independent sulfate anion transporter Solute carrier family 26 member 6 Solute carrier family 26 member 9 Sulfate anion transporter 1 Sulfate transporter	P58735 Q49B93 Q62273 Q80ZD3 Q8BU91 Q8CIW6 Q8R2Z3 Q9R155 Q9WVC8	Cfex Dra Dtd Dtdst Pat1 Pds Sat1 Slc26a1 Slc26a11 Slc26a2 Slc26a3 Slc26a4 Slc26a6 Slc26a7 Slc26a9 Slc5a12 Smct2
SMAC, XIAP-regulated apoptotic response	Caspase-3 Caspase-7 Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP Septin-4	P28661 P70677 P97864 Q60989 Q9JIQ3	Aipa Api3 Bh5 Birc4 Casp3 Casp7 Cpp32 Diablo Gm11492 Lice2 Mch3 Miha Pnutl2 Sep4 Sept4 Septin4 Smac Xiap
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	14-3-3 protein beta/alpha 5'-3' exoribonuclease 1 Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP42 Exosome complex exonuclease RRP44 MAP kinase-activated protein kinase 2 Transportin-1 m7GpppN-mRNA hydrolase mRNA decay activator protein ZFP36 mRNA-decapping enzyme 1A	P22893 P49138 P97789 Q7TQK4 Q8BFY9 Q8BTW3 Q8VBV3 Q91YD3 Q921I9 Q9CQV8 Q9CRA8 Q9CSH3 Q9CYC6 Q9D0M0 Q9D753 Q9DAA6 Q9JHI7	Csl4 D7Wsu180e Dcp1a Dcp2 Dhm2 Dis3 Exo Exosc1 Exosc2 Exosc3 Exosc4 Exosc5 Exosc6 Exosc7 Exosc8 Exosc9 Kiaa1008 Kpnb2 Mapkapk2 Mitc1 Mtr3 Nup475 Pmscl1 Rps6kc1 Rrp4 Rrp40 Rrp41 Rrp42 Rrp43 Rrp44 Rrp46 Sep1 Smif Tis11 Tis11a Tnpo1 Ttp Xrn1 Ywhab Zfp36
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15	A3KGF7 P21278 P21279 P30677 P30678 P51432 Q91UZ1 Q9Z1B3	Gna-11 Gna-14 Gna-15 Gna11 Gna14 Gna15 Gnaq Plcb Plcb1 Plcb2 Plcb3 Plcb4
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 5'-3' exonuclease PLD4 Calmodulin-1 Inositol polyphosphate 5-phosphatase OCRL Inositol-tetrakisphosphate 1-kinase Inositol-trisphosphate 3-kinase A Inositol-trisphosphate 3-kinase C Kinase Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Synaptojanin-1 Type II inositol 1,4,5-trisphosphate 5-phosphatase	A2AP18 A3KGF7 B2RXC2 O08586 P0DP26 P51432 P59644 Q4KWH5 Q62077 Q6NVF0 Q6P549 Q7TS72 Q8BG07 Q8BYN3 Q8CHC4 Q8CIH5 Q8K2J0 Q8K337 Q8K3R3 Q8K4D7 Q8K4S1 Q8R071 Q8R3B1 Q91UZ1 Q9ES52 Q9Z1B3	7a33 Calm Calm1 Cam Cam1 Inpp5b Inpp5d Inpp5j Inppl1 Itpk1 Itpka Itpkb Itpkc Kiaa0910 Kiaa1069 Kiaa1516 Kiaa1964 Mmac1 Ocrl Ocrl1 Pib5pa Plcb Plcb1 Plcb2 Plcb3 Plcb4 Plcd Plcd1 Plcd3 Plcd4 Plce Plce1 Plcg-1 Plcg1 Plcg2 Plch1 Plch2 Plcl3 Plcl4 Plcz1 Pld4 Pten Ship Ship1 Ship2 Synj1
RND2 GTPase cycle	Aldehyde dehydrogenase family 3 member A2 Ankyrin repeat domain-containing protein 26 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 Bridge-like lipid transfer protein family member 3B Caveolin-1 Cytoskeleton-associated protein 4 DEP domain-containing protein 1B Desmoglein-1-alpha Disks large homolog 5 Dystonin Ephrin type-A receptor 2 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Formin-binding protein 1 Golgin subfamily A member 3 Inactive tyrosine-protein kinase PRAG1 Kinase D-interacting substrate 220 Kinectin Kinesin-like protein KIF14 Leucine-rich repeat-containing protein 1 Mucin-13 Nischarin Nuclear migration protein nudC Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plakophilin-4 Plexin-D1 Protein FAM83B Protein scribble homolog RNA-binding motif protein, X chromosome RNA-binding protein 39 Rho GTPase-activating protein 1 Rho GTPase-activating protein 35 Rho GTPase-activating protein 5 Rho-related GTP-binding protein RhoN Thioredoxin-like protein 1 Transferrin receptor protein 1 Tyrosine-protein phosphatase non-receptor type 13 UBX domain-containing protein 11 Vang-like protein 1 Vang-like protein 2 tRNA (34-2'-O)-methyltransferase regulator WDR6	A2RSJ4 E9Q9B7 E9Q9R9 L0N7N1 O08908 O35685 O70479 P19467 P26450 P47740 P49817 P55937 P97393 Q03145 Q0VBM2 Q3UH93 Q571I4 Q5FWK3 Q61495 Q61595 Q62351 Q64512 Q68FH0 Q80TM9 Q80TY0 Q80U72 Q80VQ1 Q80Z96 Q811D2 Q8BGV7 Q8BH88 Q8BMK4 Q8C180 Q8CDN6 Q8VH51 Q91WJ0 Q91YM2 Q91ZD4 Q91ZU6 Q99ME2 Q9D572 Q9QYM5 Q9WV02	Ahd-3 Ahd3 Aldh3 Aldh3a2 Aldh4 Ankrd26 Arhgap1 Arhgap35 Arhgap5 Arhn Armrp Bltp3b Bpag1 Caper Cav Cav1 Ckap4 D4Bwg1540e D8Ertd82e Depdc1b Dlg5 Dsg1 Dsg1a Dst Eck Edp1 Epha2 Fam83b Fbp17 Fnbp1 Frs2 Frs2a Frs2b Frs3 Golga3 Grlf1 Hnrnpg Hnrpg Kctd13 Kiaa0147 Kiaa0554 Kiaa0701 Kiaa0975 Kiaa1074 Kiaa1722 Kidins220 Kif14 Ktn1 Lap4 Lpp1 Lpp2 Lrrc1 Ltap Ly64 Macf2 Mea2 Muc13 Myk2 Nack Nisch Nudc P190A Pik3r1 Pik3r2 Pkp4 Plxnd1 Poldip1 Prag1 Ptp14 Ptpn13 Rbm39 Rbmx Rbmxp1 Rbmxrt Rho7 Rhogap5 Rhon Rnd2 Rnpc2 Scrib Scrib1 Sek2 Sgk223 Ship164 Soc Tfrc Tnfaip1 Trfr Trp32 Txnl Txnl1 Ubxd5 Ubxn11 Uhrf1bp1l Vangl1 Vangl2 Wdr6 p190ARHOGAP
RHO GTPases activate PAKs	Calmodulin-1 Cell division control protein 42 homolog Filamin-A LIM domain kinase 1 Merlin Myosin light chain kinase, smooth muscle Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein phosphatase PP1-beta catalytic subunit	O08638 O88643 P0DP26 P46662 P53668 P60766 P62141 P63001 Q3THE2 Q60605 Q61036 Q61879 Q6PDN3 Q6URW6 Q8BG95 Q8BTM8 Q8CIN4 Q8VDD5 Q9CQ19 Q9DBR7	Calm Calm1 Cam Cam1 Cdc42 Fln Fln1 Flna Limk Limk1 Mrlc2 Myh10 Myh11 Myh14 Myh9 Myl12b Myl6 Myl9 Mylc2b Mylk Myln Mypt1 Mypt2 Myrl2 Nf-2 Nf2 Pak-3 Pak1 Pak2 Pak3 Paka Pakb Ppp1cb Ppp1r12a Ppp1r12b Rac1 Stk4
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	P53349 P70196 Q9QZH6	Ecsit Map3k1 Mekk Mekk1 Sitpec Traf6

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