Sema4D induced cell migration and growth-cone collapse
|
|
|
- Arha
- Arha2
- Arhb
- Arhc
- Arhgef11
- Arhgef12
- Erbb2
- Kiaa0382
- Kiaa0407
- Kiaa3023
- Larg
- Neu
- Plxnb1
- Rho6
- Rhoa
- Rhob
- Rhoc
- Rnd1
- Rock1
- Rock2
- Sema4d
- Semacl2
- Semaj
|
|
Sema4D mediated inhibition of cell attachment and migration
|
|
|
- Arha
- Arha2
- Arhgap35
- Grlf1
- Kiaa0407
- Kiaa1722
- Met
- P190A
- Plxnb1
- Rac1
- Rho6
- Rhoa
- Rnd1
- Rras
- Sema4d
- Semacl2
- Semaj
- p190ARHOGAP
|
|
Other semaphorin interactions
|
|
|
- Cd108
- Cd72
- Dap12
- Karap
- Kiaa1206
- Kiaa1479
- Kiaa4053
- Ly-32
- Ly-5
- Ly32
- Lyb-2
- Plxn6
- Plxna1
- Plxnb3
- Plxnc1
- Plxnd1
- Ptprc
- SemB
- SemF
- Sema3e
- Sema4a
- Sema4d
- Sema5a
- Sema6d
- Sema7a
- Semab
- Semacl2
- Semaf
- Semah
- Semaj
- Semal
- Semh
- Semk1
- Trem2
- Trem2a
- Trem2b
- Trem2c
- Tyrobp
- Vespr
|
|
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
|
|
|
- Akr1c20
- Akr1c21
- Akr1c6
- Cbr
- Cbr1
- Cox-1
- Cox-2
- Cox1
- Cox2
- Cyp12
- Cyp5
- Cyp5a1
- Cyp8
- Cyp8b1
- Gbf1
- Gsts
- Hpgds
- Hsd17b5
- Pgds
- Pges
- Pges2
- Pghs-b
- Ptgds
- Ptgds2
- Ptges
- Ptges2
- Ptges3
- Ptgis
- Ptgs1
- Ptgs2
- Sid3177
- Tbxas1
- Tebp
- Tis10
|
|
RAF-independent MAPK1/3 activation
|
|
|
- 3ch134
- Dusp1
- Dusp10
- Dusp16
- Dusp2
- Dusp4
- Dusp5
- Dusp6
- Dusp7
- Dusp8
- Dusp9
- Erk1
- Erk2
- Mapk
- Mapk1
- Mapk3
- Mkp1
- Mkp3
- Mkp5
- Nttp1
- Pac-1
- Pac1
- Pea15
- Pea15a
- Prkm1
- Prkm3
- Ptpn10
- Ptpn16
|
|
activated TAK1 mediates p38 MAPK activation
|
|
|
- Blu
- Card15
- Crk1
- Croc1
- Csbp1
- Csbp2
- Ikbkg
- Il1rak
- Irak1
- Irak2
- Kiaa0733
- Kiaa4135
- Map2k3
- Map2k6
- Map3k7
- Map3k7ip1
- Map3k7ip2
- Map3k7ip3
- Mapk11
- Mapk14
- Mapkapk2
- Mapkapk3
- Mkk3
- Nemo
- Nod1
- Nod2
- Prkm11
- Prkmk3
- Prkmk6
- Rip2
- Ripk2
- Rps6kc1
- Sapkk3
- Tab1
- Tab2
- Tab3
- Tak1
- Traf6
- Ube2n
- Ube2v1
|
|
Oxidative Stress Induced Senescence
|
|
|
- Ask1
- Cdk4
- Cdk6
- Cdkn2b
- Cdkn6
- Crk1
- Crk2
- Crk3
- Csbp1
- Csbp2
- D11Ertd530e
- Eed
- Enx1h
- Erk1
- Erk2
- Ezh2
- Fos
- Jmjd3
- Jnk1
- Jnk2
- Jnk3
- Jnkk1
- Jun
- Kdm6b
- Kiaa0160
- Kiaa0346
- Kiaa0551
- Map2k3
- Map2k4
- Map2k6
- Map2k7
- Map3k5
- Map4k4
- Map4k6
- Mapk
- Mapk1
- Mapk10
- Mapk11
- Mapk14
- Mapk3
- Mapk8
- Mapk9
- Mapkapk2
- Mapkapk3
- Mapkapk5
- Mdm2
- Mdm4
- Mdmx
- Mek4
- Mekk5
- Mink
- Mink1
- Mkk3
- Mkk4
- Mkk7
- Nik
- P53
- Prkm1
- Prkm10
- Prkm11
- Prkm3
- Prkm8
- Prkm9
- Prkmk3
- Prkmk4
- Prkmk6
- Rbap46
- Rbap48
- Rbbp4
- Rbbp7
- Rps27a
- Rps6kc1
- Sapkk3
- Sek1
- Serk1
- Serk2
- Skk1
- Suz12
- Tnik
- Tp53
- Trp53
- Txn
- Txn1
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Reactions specific to the complex N-glycan synthesis pathway
|
|
|
- Cga
- Chst10
- Chst8
- Fuca
- Fuca1
- Fut8
- Lhb
- Man2a1
- Man2a2
- Mana2
- Mana2x
- Mgat2
|
|
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
|
|
|
- Atad2
- Cga
- Esr
- Esr1
- Estr
- Estra
- Lhb
- Nr3a1
|
|
Hormone ligand-binding receptors
|
|
|
- Cga
- Fshb
- Fshr
- Gnrh
- Gnrh1
- Gnrhr
- Gpa2
- Gpb5
- Gpha2
- Gphb5
- Lhb
- Lhcgr
- Lhr
- Tshb
- Tshr
- Zlut1
- Zsig51
|
|
Relaxin receptors
|
|
|
- Gm1018
- Gpr100
- Gpr106
- Great
- Insl3
- Insl5
- Insl7
- Lgr7
- Lgr8
- Rif
- Rif2
- Rlf
- Rln
- Rln1
- Rln3
- Rln3r1
- Rln3r2
- Rlx
- Rxfp1
- Rxfp2
- Rxfp3
- Rxfp4
- Salpr
- Zins3
|
|
Regulation of MITF-M-dependent genes involved in apoptosis
|
|
|
- Hdac1
- Hint
- Hint1
- Kiaa4126
- Pkci
- Pkci1
- Prkcnh1
- Sin3a
|
|
Regulation of MECP2 expression and activity
|
|
|
- Hdac1
- Hdac2
- Hipk2
- Kiaa4126
- Lbr
- Nbak1
- Sin3a
- Stank
- Yy1bp
|
|
G0 and Early G1
|
|
|
- Bara
- Ccna
- Ccna1
- Ccna2
- Ccne
- Ccne1
- Ccne2
- Cdk2
- Cdkn2
- Cyca
- Cyca2
- Dp2
- Dyrk
- Dyrk1a
- E2f4
- E2f5
- Hdac1
- Kiaa2037
- Lin37
- Lin52
- Lin54
- Lin9
- Rbap48
- Rbbp4
- Rbl1
- Rbl2
- Tfdp1
- Tfdp2
- Tgs1
|
|
Deactivation of the beta-catenin transactivating complex
|
|
|
- Aipa
- Akt
- Akt1
- Akt2
- Apc
- Api3
- Birc4
- Catnb
- Catnbip1
- Cby
- Cby1
- Chd8
- Crm1
- Ctbp1
- Ctnnb1
- Ctnnbip1
- Esg
- Grg1
- Grg2
- Grg4
- Hdac1
- Icat
- Kiaa1564
- Lef1
- Miha
- Pgea1
- Rac
- Rps27a
- Sox-13
- Sox-17
- Sox-2
- Sox-3
- Sox-4
- Sox-6
- Sox-7
- Sox-9
- Sox13
- Sox17
- Sox2
- Sox3
- Sox4
- Sox6
- Sox7
- Sox9
- Tcf-1
- Tcf1
- Tcf3
- Tcf4
- Tcf7
- Tcf7l1
- Tcf7l2
- Tle1
- Tle2
- Tle3
- Tle4
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Xiap
- Xpo1
- Ywhaz
|
|
Cross-presentation of soluble exogenous antigens (endosomes)
|
|
|
- Cd207
- Clec4k
- Fcg1
- Fcgr1
- Kiaa0072
- Kiaa0077
- Kiaa0709
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mrc1
- Mrc2
- Mss1
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Ring12
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
|
|
Regulation of RUNX2 expression and activity
|
|
|
- Chip
- Cul1
- Kiaa0072
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psmb1
- Psmb10
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psmf1
- Rbx1
- Ring12
- Rps27a
- Skp1
- Skp1a
- Skp2
- Stub1
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
|
|
|
- Cul1
- Gsk3b
- Kiaa0072
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Nfe2l2
- Nrf2
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psmb1
- Psmb10
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psmf1
- Rbx1
- Ring12
- Rps27a
- Skp1
- Skp1a
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
NIK-->noncanonical NF-kB signaling
|
|
|
- Btrcp2
- Chuk
- Cul1
- Fbw1b
- Fbxw11
- Fbxw1b
- Ikka
- Kiaa0072
- Kiaa0077
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Map3k14
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Nfkb2
- Nik
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Relb
- Ring12
- Rps27a
- Skp1
- Skp1a
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
- Uba3
- Uba52
- Uba80
- Ubb
- Ubc
- Ubc-rs2
- Ubc12
- Ubcep1
- Ubcep2
- Ube1c
- Ube2m
|
|
Dectin-1 mediated noncanonical NF-kB signaling
|
|
|
- Btrcp2
- Chuk
- Cul1
- Fbw1b
- Fbxw11
- Fbxw1b
- Ikka
- Kiaa0072
- Kiaa0077
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Map3k14
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Nfkb2
- Nik
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Relb
- Ring12
- Rps27a
- Skp1
- Skp1a
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
- Uba3
- Uba52
- Uba80
- Ubb
- Ubc
- Ubc-rs2
- Ubc12
- Ubcep1
- Ubcep2
- Ube1c
- Ube2m
|
|
Degradation of DVL
|
|
|
- C3ip1
- Cul3
- Dact1
- Dvl
- Dvl1
- Dvl2
- Dvl3
- Hecw1
- Kiaa0072
- Kiaa0077
- Kiaa0322
- Klhl12
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Nedl1
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Rbx1
- Ring12
- Rps27a
- Sug1
- Sug2
- Tbp1
- Tbp7
- Thyex3
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Degradation of GLI1 by the proteasome
|
|
|
- Cul1
- Gli
- Gli1
- Itch
- Kiaa0072
- Kiaa0077
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Numb
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Rbx1
- Ring12
- Rps27a
- Skp1
- Skp1a
- Sufu
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
|
|
|
- Ajuba
- Cul2
- Egln1
- Egln2
- Egln3
- Elob
- Eloc
- Epas1
- Hif1a
- Hif2a
- Hif3a
- Jub
- Kiaa0072
- Kiaa0077
- Limd1
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mop7
- Mov-34
- Mov34
- Mss1
- Nepas
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Rbx1
- Ring12
- Rps27a
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tceb1
- Tceb2
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubc4
- Ubcep1
- Ubcep2
- Ubch4
- Ubch5b
- Ube2d1
- Ube2d2
- Ube2d2a
- Ube2d3
- Vhl
- Vhlh
- Wtip
|
|
KEAP1-NFE2L2 pathway
|
|
|
- A170
- Akt
- Akt1
- Akt2
- Akt3
- Cul3
- Gide
- Inrf2
- Keap1
- Kiaa0072
- Kiaa0077
- Kiaa0132
- Kiaa0794
- Kiaa1499
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Map1alc3
- Map1lc3
- Map1lc3b
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Mul1
- Nfe2l2
- Npl4
- Nploc4
- Nrf2
- P91a
- Pa26
- Pa28b1
- Pad1
- Pkcl
- Prkci
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Rac
- Rbx1
- Ring12
- Ro52
- Rps27a
- STAP
- Sesn1
- Sesn2
- Sest1
- Sqstm1
- Ssa1
- Sug1
- Sug2
- Tbp1
- Tbp7
- Trim21
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Ubxd7
- Ubxn7
- Ufd1
- Ufd1l
- Vcp
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Ubiquitin-dependent degradation of Cyclin D
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- Ccnd1
- Cdk4
- Crk3
- Cyl-1
- Kiaa0072
- Kiaa0077
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Ring12
- Rps27a
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
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