cGMP effects
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- Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
- Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
- Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
- High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
- Inositol 1,4,5-triphosphate receptor associated 1
- Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
- cGMP-dependent 3',5'-cyclic phosphodiesterase
- cGMP-dependent protein kinase 1
- cGMP-dependent protein kinase 2
- cGMP-specific 3',5'-cyclic phosphodiesterase
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- Insp3r
- Irag
- Irag1
- Itpr1
- Mrvi1
- Pcd6
- Pcp1
- Pde10a
- Pde11a
- Pde1a
- Pde1b
- Pde1b1
- Pde2a
- Pde5
- Pde5a
- Pde8b
- Pde9a
- Prkg1
- Prkg1b
- Prkg2
- Prkgr1a
- Prkgr1b
- Prkgr2
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Toll Like Receptor 4 (TLR4) Cascade
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- Bpi
- Cd14
- Cd180
- Dnm
- Dnm1
- Dnm2
- Dnm3
- Dyn2
- Esop1
- Itgam
- Itgb2
- Kiaa0820
- Kiaa4093
- Lbp
- Lps
- Ly78
- Ly86
- Ly96
- Md1
- Md2
- Plcg2
- Ptpn4
- Rp105
- Ticam2
- Tirp
- Tlr4
- Tram
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Potassium transport channels
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TAK1-dependent IKK and NF-kappa-B activation
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- A4
- AD1
- Ager
- Alpk1
- App
- Blu
- Chuk
- Croc1
- Hmg-1
- Hmg1
- Hmgb1
- Ikba
- Ikbb
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Il1rak
- Irak1
- Irak2
- Kiaa0733
- Kiaa1527
- Kiaa4135
- Map3k7
- Map3k7ip1
- Map3k7ip2
- Map3k7ip3
- Nemo
- Nfkb1
- Nfkb2
- Nfkb3
- Nfkbia
- Nfkbib
- Nkiras1
- Nkiras2
- Rage
- Rela
- Rps27a
- S100b
- T2bp
- Tab1
- Tab2
- Tab3
- Tak1
- Tifa
- Traf6
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Ube2n
- Ube2v1
- Ubp43
- Usp18
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MAP3K8 (TPL2)-dependent MAPK1/3 activation
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- Abin2
- Btrcp2
- Chuk
- Cot
- Cul1
- Fbw1b
- Fbxw11
- Fbxw1b
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Map3k8
- Nemo
- Nfkb1
- Rps27a
- Skp1
- Skp1a
- Tnip2
- Tpl2
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
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TRAF6 mediated NF-kB activation
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- A4
- AD1
- Ager
- App
- Chuk
- Hmg-1
- Hmg1
- Hmgb1
- Ikba
- Ikbb
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Nemo
- Nfkb1
- Nfkb2
- Nfkb3
- Nfkbia
- Nfkbib
- Nkiras1
- Nkiras2
- Rage
- Rela
- S100b
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IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
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- Blu
- Chuk
- Croc1
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Il1rak
- Irak1
- Nemo
- Peli1
- Peli2
- Peli3
- Traf6
- Ube2n
- Ube2v1
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IRAK1 recruits IKK complex
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- Blu
- Chuk
- Croc1
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Il1rak
- Irak1
- Nemo
- Peli1
- Peli2
- Peli3
- Traf6
- Ube2n
- Ube2v1
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p75NTR recruits signalling complexes
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- A170
- Ikbkb
- Ikkb
- Il1rak
- Irak1
- Myd88
- Ngf
- Ngfb
- Ngfr
- Pkcl
- Prkci
- Rip2
- Ripk2
- Rps27a
- STAP
- Sqstm1
- Tnfrsf16
- Traf6
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
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NF-kB is activated and signals survival
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- A170
- Ikba
- Ikbkb
- Ikkb
- Il1rak
- Irak1
- Nfkb1
- Nfkb3
- Nfkbia
- Ngf
- Ngfb
- Ngfr
- Rela
- Rps27a
- STAP
- Sqstm1
- Tnfrsf16
- Traf6
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
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FGFR1c ligand binding and activation
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- Aigf
- Fgf-1
- Fgf-2
- Fgf-4
- Fgf-5
- Fgf-6
- Fgf-9
- Fgf1
- Fgf17
- Fgf2
- Fgf20
- Fgf23
- Fgf4
- Fgf5
- Fgf6
- Fgf8
- Fgf9
- Fgfa
- Fgfr1
- Flg
- Gipc
- Gipc1
- Hstf2
- Kfgf
- Rgs19ip1
- Semcap1
- Tgfbr3
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Signaling by Activin
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- Acvr1b
- Acvr1c
- Acvr2
- Acvr2a
- Acvr2b
- Alk4
- Alk7
- Dpc4
- Erk1
- Erk2
- Inha
- Inhba
- Inhbb
- Madh2
- Madh3
- Madh4
- Madr2
- Mapk
- Mapk1
- Mapk3
- Prkm1
- Prkm3
- Smad2
- Smad3
- Smad4
- Tgfbr3
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Transport and synthesis of PAPS
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- Asapk
- Atpsk1
- Atpsk2
- Dtd
- Dtdst
- J207
- Papss
- Papss1
- Papss2
- Sat1
- Slc26a1
- Slc26a2
- Slc35b2
- Slc35b3
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PKA activation
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- Adcy1
- Adcy2
- Adcy3
- Adcy4
- Adcy5
- Adcy6
- Adcy7
- Adcy8
- Adcy9
- Calm
- Calm1
- Cam
- Cam1
- Kiaa1060
- Pkaca
- Pkacb
- Prkaca
- Prkacb
- Prkar1a
- Prkar1b
- Prkar2a
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Adenylate cyclase activating pathway
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- Adcy1
- Adcy2
- Adcy3
- Adcy4
- Adcy5
- Adcy6
- Adcy7
- Adcy8
- Adcy9
- Gnal
- Kiaa1060
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RHO GTPases activate KTN1
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- Arha
- Arha2
- Arhg
- Cdc42
- Khcs
- Kiaa4086
- Kif5
- Kif5a
- Kif5b
- Klc1
- Klc2
- Klc3
- Klc4
- Kns1
- Kns2
- Knsl8
- Ktn1
- Nkhc1
- Rac1
- Rhoa
- Rhog
- Sid10750
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TWIK related potassium channel (TREK)
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Bloch pathway
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- Dhcr24
- Dhcr7
- Ebp
- Kiaa0018
- Msi
- Sc5d
- Sc5dl
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Kandutsch-Russell pathway
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- Dhcr24
- Dhcr7
- Ebp
- Kiaa0018
- Msi
- Sc5d
- Sc5dl
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Aggrephagy
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- Abcc7
- Arl13b
- Arl2l1
- Blu
- Calt
- Cetn1
- Cftr
- Croc1
- Dhc1
- Dlc1
- Dlc2
- Dnch1
- Dnchc1
- Dnci1
- Dnci2
- Dncic1
- Dncic2
- Dncl1
- Dnclc1
- Dncli1
- Dncli2
- Dnclic1
- Dnclic2
- Dyhc
- Dync1h1
- Dync1i1
- Dync1i2
- Dync1li1
- Dync1li2
- Dynll1
- Dynll2
- Hdac6
- Ift88
- Park2
- Park7
- Pcnt
- Pcnt2
- Prkn
- Rps27a
- Tg737
- Tg737Rpw
- TgN737Rpw
- Ttc10
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Ube2n
- Ube2v1
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SUMOylation of DNA methylation proteins
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- Dnmt
- Dnmt1
- Dnmt3b
- Met1
- Smt3c
- Smt3h3
- Sumo1
- Ubc9
- Ubce2i
- Ubce9
- Ube2i
- Ubl1
- Uim
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Switching of origins to a post-replicative state
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- Bm28
- Cdc21
- Cdc46
- Cdc47
- Cdcl1
- Cdt1
- Gmnn
- Kiaa0030
- Mcm2
- Mcm3
- Mcm4
- Mcm5
- Mcm6
- Mcm7
- Mcmd
- Mcmd2
- Mcmd3
- Mcmd4
- Mcmd5
- Mcmd6
- Mcmd7
- Mis5
- Ris2
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JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
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- Blu
- Card15
- Croc1
- Ikbkg
- Il1rak
- Irak1
- Irak2
- Jnk1
- Jnk2
- Jnk3
- Jnkk1
- Kiaa0733
- Kiaa4135
- Map2k4
- Map2k7
- Map3k7
- Map3k7ip1
- Map3k7ip2
- Map3k7ip3
- Mapk10
- Mapk8
- Mapk9
- Mek4
- Mkk4
- Mkk7
- Nemo
- Nod1
- Nod2
- Prkm10
- Prkm8
- Prkm9
- Prkmk4
- Rip2
- Ripk2
- Sek1
- Serk1
- Serk2
- Skk1
- Tab1
- Tab2
- Tab3
- Tak1
- Traf6
- Ube2n
- Ube2v1
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Catecholamine biosynthesis
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RHOBTB1 GTPase cycle
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- Bre1a
- Cct2
- Cct7
- Cctb
- Ccth
- Cops1
- Cops2
- Cops4
- Cpsf7
- Csn1
- Csn2
- Csn4
- Cul3
- Gps1
- Hnrnpc
- Hnrnpg
- Hnrpc
- Hnrpg
- Kiaa0929
- Kiaa4116
- Mint
- Myo6
- Ndr1
- P2pr
- Pact
- Pde5
- Pde5a
- Pop101
- Rbbp6
- Rbmx
- Rbmxp1
- Rbmxrt
- Rhobtb1
- Rnf20
- Rock1
- Rock2
- Sfrs10
- Sharp
- Silg41
- Spen
- Srrm1
- Stk38
- Sv
- Tra2b
- Trip15
- Trp32
- Txnl
- Txnl1
- Vim
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