Negative regulation of FLT3
|
|
|
- Abl2
- Arg
- Byp
- Cbl
- Cis2
- Cis4
- Cish2
- Cish4
- Csk
- Flk-2
- Flt-3
- Flt3
- Flt3l
- Flt3lg
- Lnk
- Ptprj
- Rps27a
- Scc1
- Sh2b3
- Sla
- Sla2
- Slap
- Slap1
- Socs2
- Socs4
- Socs6
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
|
|
|
- Ffar1
- Gna-11
- Gna-14
- Gna-15
- Gna11
- Gna14
- Gna15
- Gnaq
- Gpr40
- Plcb
- Plcb1
- Plcb2
- Plcb3
|
|
Sodium-coupled sulphate, di- and tri-carboxylate transporters
|
|
|
- Nact
- Nadc1
- Nadc3
- Nas1
- Nasi1
- Sdct1
- Sdct2
- Slc13a1
- Slc13a2
- Slc13a3
- Slc13a4
- Slc13a5
|
|
Growth hormone receptor signaling
|
|
|
- Erk1
- Erk2
- Gh
- Gh1
- Ghr
- Jak2
- Lyn
- Mapk
- Mapk1
- Mapk3
- Mgf
- Mpf
- Prkm1
- Prkm3
- Prl
- Prlr
- Ptpn1
- Sh2b1
- Sh2bpsm1
- Stat5a
- Stat5b
|
|
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
|
|
|
- Akt
- Akt1
- Akt2
- Akt3
- Cdkn1b
- Creb-1
- Creb1
- Crm1
- Erk2
- Fkhr2
- Foxo3
- Foxo3a
- Kis
- Kist
- Mapk
- Mapk1
- Prkm1
- Rac
- Uhmk1
- Xpo1
|
|
SHC1 events in ERBB2 signaling
|
|
|
- Bcn
- Btc
- Dtr
- Egf
- Egfr
- Erbb2
- Erbb3
- Erbb4
- Ereg
- Hbegf
- Hegfl
- Kiaa3023
- Mer4
- Neu
- Nrg1
- Nrg2
- Nrg3
- Pkca
- Pkcd
- Pkce
- Pkcea
- Prkca
- Prkcd
- Prkce
- Ptpn12
|
|
MET activates PTK2 signaling
|
|
|
- Egfl3
- Hgf
- Itga2
- Itga3
- Itgb1
- Lama4
- Megf6
- Met
- Src
|
|
IRAK1 recruits IKK complex
|
|
|
- Blu
- Chuk
- Croc1
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Il1rak
- Irak1
- Nemo
- Peli1
- Peli2
- Peli3
- Traf6
- Ube2n
- Ube2v1
|
|
Beta oxidation of myristoyl-CoA to lauroyl-CoA
|
|
|
|
|
Heme biosynthesis
|
|
|
- Abcg2
- Abcp
- Alad
- Alas1
- Alas2
- Alb
- Alb-1
- Alb1
- Bcrp1
- Cox10
- Cox15
- Cpo
- Cpox
- Fech
- Flvcr1
- Hmbs
- Lv
- Mfsd7b
- Ppox
- Urod
- Uros
- Uros1
- Uros3
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|
FGFR1b ligand binding and activation
|
|
|
- Fgf-1
- Fgf-2
- Fgf-3
- Fgf1
- Fgf10
- Fgf2
- Fgf22
- Fgf3
- Fgfa
- Fgfr1
- Flg
- Gipc
- Gipc1
- Int-2
- Rgs19ip1
- Semcap1
- Tgfbr3
|
|
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
|
|
|
|
|
RIP-mediated NFkB activation via ZBP1
|
|
|
- Chuk
- Ddx9
- Dhx9
- Ikba
- Ikbb
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Myd88
- Nemo
- Nfkb1
- Nfkb2
- Nfkb3
- Nfkbia
- Nfkbib
- Nkiras1
- Nkiras2
- Rela
|
|
Serine biosynthesis
|
|
|
- Aigp1
- Aigp2
- Aigp3
- Diff33
- Phgdh
- Psa
- Psat
- Psat1
- Psph
- Serinc1
- Serinc2
- Serinc3
- Serinc4
- Serinc5
- Srr
- Tde1
- Tde1l
- Tde2
- Tde2l
- Tms1
- Tms2
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|
Translesion synthesis by REV1
|
|
|
- Ibf-1
- Mad2b
- Mad2l2
- Pcna
- Polz
- Recc1
- Rev1
- Rev1l
- Rev3l
- Rev7
- Rfc1
- Rfc2
- Rfc3
- Rfc4
- Rfc5
- Rpa1
- Rpa2
- Rpa3
- Rpa34
- Rps27a
- Sez4
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Telomere Extension By Telomerase
|
|
|
- Acd
- Ankrd28
- Ccna
- Ccna1
- Ccna2
- Cdk2
- Cdkn2
- Cyca
- Cyca2
- D19Ertd703e
- Dkc1
- Gar1
- Kiaa1088
- Kiaa1558
- Nhp2
- Nola1
- Nola2
- Nola3
- Nop10
- Pif1
- Pot1
- Pot1a
- Pp6r3
- Ppp6c
- Ppp6r3
- Rap1
- Rtel
- Rtel1
- Saps3
- Shq1
- Tcab1
- Terf1
- Terf2
- Terf2ip
- Tert
- Tin2
- Tinf2
- Trf1
- Trf2
- Wdr79
- Wrap53
|
|
RAF/MAP kinase cascade
|
- Alpha-actinin-2
- Amphiregulin
- Angiopoietin-1 receptor
- Angiopoietin-1
- Artemin
- Astrocytic phosphoprotein PEA-15
- Beta-klotho
- Calcium/calmodulin-dependent protein kinase type II subunit alpha
- Calcium/calmodulin-dependent protein kinase type II subunit beta
- Calcium/calmodulin-dependent protein kinase type II subunit delta
- Calcium/calmodulin-dependent protein kinase type II subunit gamma
- Calmodulin-1
- Cytokine receptor common subunit beta
- Cytokine receptor common subunit gamma
- Disks large homolog 1
- Disks large homolog 2
- Disks large homolog 3
- Disks large homolog 4
- Epidermal growth factor receptor
- Epigen
- Fibroblast growth factor 10
- Fibroblast growth factor 15
- Fibroblast growth factor 16
- Fibroblast growth factor 17
- Fibroblast growth factor 18
- Fibroblast growth factor 1
- Fibroblast growth factor 20
- Fibroblast growth factor 22
- Fibroblast growth factor 23
- Fibroblast growth factor 2
- Fibroblast growth factor 3
- Fibroblast growth factor 4
- Fibroblast growth factor 5
- Fibroblast growth factor 6
- Fibroblast growth factor 7
- Fibroblast growth factor 8
- Fibroblast growth factor 9
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor 4
- Fibroblast growth factor receptor substrate 2
- Fibroblast growth factor receptor substrate 3
- Fms-related tyrosine kinase 3 ligand
- GDNF family receptor alpha-1
- GDNF family receptor alpha-2
- GDNF family receptor alpha-3
- GDNF family receptor alpha-4
- GTPase HRas
- GTPase KRas
- GTPase NRas
- Glial cell line-derived neurotrophic factor
- Glutamate receptor ionotropic, NMDA 1
- Glutamate receptor ionotropic, NMDA 2B
- Glutamate receptor ionotropic, NMDA 2D
- Granulocyte-macrophage colony-stimulating factor
- Hepatocyte growth factor receptor
- Hepatocyte growth factor
- Insulin receptor substrate 1
- Insulin receptor substrate 2
- Interleukin-2 receptor subunit alpha
- Interleukin-2 receptor subunit beta
- Interleukin-2
- Interleukin-3 receptor class 2 subunit beta
- Interleukin-3
- Interleukin-5 receptor subunit alpha
- Interleukin-5
- Kit ligand
- Klotho
- Leucine-rich repeat-containing protein 7
- Linker for activation of T-cells family member 1
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 3
- Neural cell adhesion molecule 1
- Neurofilament light polypeptide
- Neurturin
- Persephin
- Phosphatidylinositol 3-kinase regulatory subunit alpha
- Phosphatidylinositol 3-kinase regulatory subunit beta
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Platelet-derived growth factor subunit A
- Platelet-derived growth factor subunit B
- Pro-epidermal growth factor
- Pro-neuregulin-1, membrane-bound isoform
- Pro-neuregulin-2, membrane-bound isoform
- Pro-neuregulin-3, membrane-bound isoform
- Probetacellulin
- Proepiregulin
- Proheparin-binding EGF-like growth factor
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Protransforming growth factor alpha
- RAS guanyl-releasing protein 1
- RAS guanyl-releasing protein 4
- RAS, guanyl releasing protein 3
- Ral guanine nucleotide dissociation stimulator-like 1
- Ral guanine nucleotide dissociation stimulator-like 2
- Ral guanine nucleotide dissociation stimulator-like 3
- Ral guanine nucleotide dissociation stimulator
- Ran-binding protein 9
- Rap guanine nucleotide exchange factor 2
- Ras-specific guanine nucleotide-releasing factor 1
- Ras-specific guanine nucleotide-releasing factor 2
- RasGEF domain family, member 1A
- Receptor tyrosine-protein kinase erbB-2
- Receptor tyrosine-protein kinase erbB-3
- Receptor tyrosine-protein kinase erbB-4
- Receptor-type tyrosine-protein kinase FLT3
- Receptor-type tyrosine-protein phosphatase alpha
- SHC-transforming protein 2
- SHC-transforming protein 3
- Son of sevenless homolog 1
- Spectrin alpha chain, erythrocytic 1
- Spectrin alpha chain, non-erythrocytic 1
- Spectrin beta chain, erythrocytic
- Spectrin beta chain, non-erythrocytic 1
- Spectrin beta chain
- Spectrin beta chain
- Spectrin beta, non-erythrocytic 5
- Tyrosine-protein kinase Fyn
- Tyrosine-protein kinase JAK1
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
|
|
- Actn2
- Agpt
- Ai2ca
- Aic2b
- Aigf
- Angpt1
- Areg
- Artn
- Bcn
- Bek
- Betakl
- Btc
- Calm
- Calm1
- Cam
- Cam1
- Camk2a
- Camk2b
- Camk2d
- Camk2g
- Cdc25
- Csf2
- Csf2rb
- Csf2rb1
- Csf2rb2
- Csfgm
- Csfmu
- Dlg1
- Dlg2
- Dlg3
- Dlg4
- Dlgh1
- Dlgh2
- Dlgh3
- Dlgh4
- Dtr
- Ect1
- Egf
- Egfr
- Elf
- Epgn
- Erbb2
- Erbb3
- Erbb4
- Ereg
- Erk1
- Erk2
- Fgf-1
- Fgf-2
- Fgf-3
- Fgf-4
- Fgf-5
- Fgf-6
- Fgf-7
- Fgf-9
- Fgf1
- Fgf10
- Fgf15
- Fgf16
- Fgf17
- Fgf18
- Fgf2
- Fgf20
- Fgf22
- Fgf23
- Fgf3
- Fgf4
- Fgf5
- Fgf6
- Fgf7
- Fgf8
- Fgf9
- Fgfa
- Fgfr-4
- Fgfr1
- Fgfr2
- Fgfr3
- Fgfr4
- Flg
- Flk-2
- Flt-3
- Flt3
- Flt3l
- Flt3lg
- Frs2
- Frs2a
- Frs2b
- Frs3
- Fyn
- Gdnf
- Gdnfra
- Gdnfrb
- Gfra1
- Gfra2
- Gfra3
- Gfra4
- GluN2D
- Glurz1
- Grf1
- Grf2
- Grin1
- Grin2b
- Grin2d
- Hbegf
- Hegfl
- Hgf
- Hras
- Hras1
- Hstf2
- Hyk
- Il-2
- Il-3
- Il-5
- Il2
- Il2r
- Il2ra
- Il2rb
- Il2rg
- Il3
- Il3r
- Il3rb1
- Il3rb2
- Il5
- Il5r
- Il5ra
- Int-2
- Irs-1
- Irs1
- Irs2
- Jak1
- Jak2
- Jak3
- Kfgf
- Kgf
- Kiaa0313
- Kiaa1365
- Kiaa3023
- Kiaa4163
- Kit
- Kitl
- Kitlg
- Kl
- Klb
- Kras
- Kras2
- Lap1
- Lat
- Lrp
- Lrrc7
- Mapk
- Mapk1
- Mapk3
- Mer4
- Met
- Mfr3
- Mgf
- Mpk-11
- Ncam
- Ncam1
- Nefl
- Neu
- Nf68
- Nfl
- Nras
- Nrg1
- Nrg2
- Nrg3
- Nrtn
- Nshc
- Pdgfa
- Pdgfb
- Pdgfr
- Pdgfr1
- Pdgfra
- Pdgfrb
- Pdzgef1
- Pea15
- Pea15a
- Pik3ca
- Pik3cb
- Pik3r1
- Pik3r2
- Prkm1
- Prkm3
- Psd95
- Pspn
- Ptpa
- Ptpra
- Rab2l
- Ralgds
- Ranbp9
- Ranbpm
- Rapgef2
- Rasgef1a
- Rasgrf1
- Rasgrf2
- Rasgrp
- Rasgrp1
- Rasgrp3
- Rasgrp4
- Ret
- Rgds
- Rgl
- Rgl1
- Rgl2
- Rgl3
- Rlf
- Sam3
- Sck
- Sdgf
- Shc2
- Shc3
- ShcB
- ShcC
- Sis
- Sl
- Slf
- Sos1
- Spna1
- Spna2
- Spnb-1
- Spnb-2
- Spnb1
- Spnb2
- Spnb3
- Spnb4
- Spta
- Spta1
- Spta2
- Sptan1
- Sptb
- Sptb1
- Sptb2
- Sptbn1
- Sptbn2
- Sptbn4
- Sptbn5
- Tek
- Tgfa
- Tie-2
- Tie2
- Trnr1
- Trnr2
|
|
Dermatan sulfate biosynthesis
|
|
|
- An2
- Bcan
- Bgn
- Caleb
- Chst14
- Cspg2
- Cspg3
- Cspg4
- Cspg5
- D4st1
- Dcn
- Dse
- Dsel
- Kiaa4232
- Ncan
- Ng2
- Ngc
- Sart2
- Ust
- Vcan
|
|
Sulfide oxidation to sulfate
|
|
|
- Dic
- Ethe1
- Hsco
- Slc25a10
- Sqor
- Sqrdl
- Suox
- Tstd1
|
|
RA biosynthesis pathway
|
|
|
- Adh-1
- Adh1
- Adh2
- Adh4
- Ahd-2
- Ahd2
- Akr1c20
- Akr1c21
- Akr1c6
- Aldh1
- Aldh1a1
- Aldh1a2
- Aldh1a3
- Aldh1a7
- Aldh6
- Aldh8a1
- Arsdr1
- Crabp1
- Cyp26
- Cyp26a1
- Cyp26b1
- Cyp26c1
- D14Ucla2
- Dhrs3
- Dhrs4
- Dhrs9
- Hsd17b5
- Mdt1
- P450ra
- Pan2
- Psdr1
- Raldh2
- Raldh3
- Raldh4
- Rdh1
- Rdh10
- Rdh11
- Rdh13
- Rdh14
- Rdh4
- Rdh5
- Rdhe2
- Rsdr1
- Scdr9
- Sdr16c5
- cRDH
- rdh
|
|
Biosynthesis of DHA-derived SPMs
|
|
|
- Alox12
- Alox12l
- Alox12p
- Alox15
- Cox-2
- Cox2
- Pghs-b
- Ptgs2
- Tis10
|
|
Peroxisomal protein import
|
- 2-Hydroxyacid oxidase 1
- 2-Hydroxyacid oxidase 2
- 2-hydroxyacyl-CoA lyase 1
- 3-ketoacyl-CoA thiolase B, peroxisomal
- AN1-type zinc finger protein 6
- Acyl-coenzyme A diphosphatase NUDT19
- Acyl-coenzyme A thioesterase 1
- Acyl-coenzyme A thioesterase 2, mitochondrial
- Acyl-coenzyme A thioesterase 3
- Acyl-coenzyme A thioesterase 5
- Acyl-coenzyme A thioesterase 8
- Alanine--glyoxylate aminotransferase
- Alkyldihydroxyacetonephosphate synthase, peroxisomal
- Alpha-methylacyl-CoA racemase
- Bifunctional epoxide hydrolase 2
- Bile acid-CoA
- Carnitine O-acetyltransferase
- Catalase
- D-amino-acid oxidase
- D-aspartate oxidase
- Dehydrogenase/reductase SDR family member 4
- Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
- Dihydroxyacetone phosphate acyltransferase
- Enoyl-CoA delta isomerase 2
- Glutathione S-transferase kappa 1
- Hydroxymethylglutaryl-CoA lyase, mitochondrial
- Insulin-degrading enzyme
- Isocitrate dehydrogenase [NADP] cytoplasmic
- Lon protease homolog 2, peroxisomal
- Long-chain fatty acid transport protein 2
- Malonyl-CoA decarboxylase, mitochondrial
- Nitric oxide synthase, inducible
- Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
- Peroxisomal ATPase PEX1
- Peroxisomal ATPase PEX6
- Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
- Peroxisomal acyl-coenzyme A oxidase 1
- Peroxisomal acyl-coenzyme A oxidase 2
- Peroxisomal acyl-coenzyme A oxidase 3
- Peroxisomal bifunctional enzyme
- Peroxisomal carnitine O-octanoyltransferase
- Peroxisomal coenzyme A diphosphatase NUDT7
- Peroxisomal leader peptide-processing protease
- Peroxisomal membrane protein PEX13
- Peroxisomal membrane protein PEX14
- Peroxisomal multifunctional enzyme type 2
- Peroxisomal sarcosine oxidase
- Peroxisomal succinyl-coenzyme A thioesterase
- Peroxisomal targeting signal 2 receptor
- Peroxisomal trans-2-enoyl-CoA reductase
- Peroxisome assembly protein 12
- Peroxisome assembly protein 26
- Peroxisome biogenesis factor 10
- Peroxisome biogenesis factor 2
- Phytanoyl-CoA dioxygenase, peroxisomal
- Polyubiquitin-B
- Polyubiquitin-C
- Protein Mpv17
- Sterol carrier protein 2
- Ubiquitin carboxyl-terminal hydrolase 9X
- Ubiquitin-conjugating enzyme E2 D1
- Ubiquitin-conjugating enzyme E2 D2
- Ubiquitin-conjugating enzyme E2 D3
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-ribosomal protein eS31 fusion protein
|
|
- Acaa1
- Acaa1b
- Acot1
- Acot2
- Acot3
- Acot4
- Acot5
- Acot8
- Acox
- Acox1
- Acox2
- Acox3
- Acsvl1
- Agps
- Agxt
- Agxt1
- Amacr
- Awp1
- Baat
- Cas-1
- Cas1
- Cat
- Cot
- Crat
- Crot
- Cte1
- D14Ucla2
- D7Rp2e
- Dao
- Dao1
- Ddo
- Decr2
- Dhapat
- Dhrs4
- Ech1
- Eci2
- Edh17b4
- Ehhadh
- Eph2
- Ephx2
- Facvl1
- Fafl
- Fam
- Fatp2
- Gnpat
- Gstk1
- Hacl1
- Hao1
- Hao2
- Hao3
- Haox2
- Hmgcl
- Hpcl
- Hsd17b4
- Ide
- Idh1
- Inosl
- L-pbe
- Ln1
- Lnap1
- Lonp2
- Macr1
- Mlycd
- Mpv17
- Mte1
- Nos2
- Nudt19
- Nudt7
- Paf1
- Pahx
- Pao
- Paox
- Pdcr
- Peci
- Pecr
- Pex1
- Pex10
- Pex12
- Pex13
- Pex14
- Pex2
- Pex26
- Pex6
- Pex7
- Phyh
- Phyh2
- Pipox
- Pmp35
- Pso
- Pte1
- Pte1a
- Pte1b
- Pte2
- Pte2a
- Pte2b
- Pxmp3
- Rps27a
- Scp-2
- Scp2
- Slc27a2
- Tysnd1
- Uba52
- Uba80
- Ubb
- Ubc
- Ubc4
- Ubcep1
- Ubcep2
- Ubch4
- Ubch5b
- Ube2d1
- Ube2d2
- Ube2d2a
- Ube2d3
- Usp9x
- Vlacs
- Vlcs
- Za20d3
- Zfand6
|
|
Sphingolipid de novo biosynthesis
|
|
|
- Abcc1
- Abcc1a
- Abcc1b
- Abcg2
- Abcp
- Admp
- Bcrp1
- Cers1
- Cers2
- Cers3
- Cers4
- Cers5
- Cers6
- Cyb5b
- Cyb5m
- Degs
- Degs1
- Degs2
- Des1
- Fa2h
- Faah
- Fvt1
- Gm1964
- Kdsr
- Lass1
- Lass2
- Lass3
- Lass4
- Lass5
- Lass6
- Lcb1
- Lcb2
- Mdes
- Mdrap
- Mfsd2b
- Mrp
- Ormdl1
- Ormdl2
- Ormdl3
- Samd8
- Sgms1
- Sgms2
- Sk1
- Sphk1
- Sphk2
- Spns2
- Sptlc1
- Sptlc2
- Sptlc2l
- Sptlc3
- Sptssa
- Sptssb
- Ssspta
- Sssptb
- Tmem23
- Trh1
- Trh3
- Trh4
- Uog-1
- Uog1
|
|
Platelet homeostasis
|
|
|
- P2rx1
- P2rx2
- P2rx3
- P2rx4
- P2rx6
- P2rx7
- P2rxl1
- P2x2
- P2x4
- P2x7
- Pafah2
|
|
Regulation of FOXO transcriptional activity by acetylation
|
|
|
- Cbp
- Crebbp
- Ep300
- Fkhr
- Fkhr2
- Foxo1
- Foxo1a
- Foxo3
- Foxo3a
- Kat2b
- P300
- Pcaf
- Sir2l1
- Sir2l3
- Sirt1
- Sirt3
|
|