GlyCosmos Portal

Rattus norvegicus (Norway rat)

Summary

Taxonomy ID: 10116
PubChem Taxonomy: 10116

Genes (449) Glycans (773) Glycoproteins (2935) Lectins (166) Pathways (1070)

Displaying entries **526 - 550** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	GlyTouCan ID
Regulation of pyruvate metabolism	Armadillo repeat-containing protein 8 E3 ubiquitin-protein transferase MAEA GID complex subunit 4 GID complex subunit 8 homolog L-lactate dehydrogenase A chain Muskelin NADP-dependent malic enzyme Polyubiquitin-B Polyubiquitin-C Pyruvate kinase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase Ran-binding protein 9 Serine/threonine-protein phosphatase PGAM5, mitochondrial Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 26 non-specific serine/threonine protein kinase	A0A0G2K5C7 A0A8I5Y176 A0A8I6A5Y3 A0A8I6AAM6 D3ZWU9 F1LTR1 F1M943 M0RD14 P04642 P0CG51 P13697 P62982 Q562B5 Q566Q9 Q5RKJ1 Q63429 Q6YDN8 Q99PV3	Armc8 Gid4 Gid8 LOC100360645 LOC100362738 Ldh-1 Ldh1 Ldha Maea Me1 Mkln1 Mod-1 Mod1 Msk Nek1 Pgam5 Pkml1 Ranbp9 Rmnd5a Rmnd5b Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Wdr26
ARMS-mediated activation	Adapter molecule crk Beta-nerve growth factor High affinity nerve growth factor receptor Kinase D-interacting substrate of 220 kDa Ras-related protein Rap-1A	P25427 P35739 P62836 Q63768 Q9EQG6	Arms Crk Crko Kidins220 Krev1 Ngf Ngfb Ntrk1 Rap1a Trk Trka
NPAS4 regulates expression of target genes	Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Basic helix-loop-helix ARNT-like protein 1 Melanoma-associated antigen D1 Neuronal PAS domain-containing protein 4	P41739 Q78E60 Q8CJH6 Q9EPW1 Q9ES73	Arnt Arnt2 Arntl Bmal1 Maged1 Npas4 Nrage Nxf Tic
Thrombin signalling through proteinase activated receptors (PARs)	Beta-arrestin-1 Beta-arrestin-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Proteinase-activated receptor 1 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin Proto-oncogene tyrosine-protein kinase Src	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 A0A8J8XRQ3 D4AAI1 F2Z3T8 G3V8K2 O35353 O88302 P18292 P21708 P26824 P29066 P29067 P43425 P52287 P54311 P54313 P61954 P62882 P63077 P63086 P63219 P82471 Q920E0 Q920E1 Q9JID2 Q9WUD9	Arrb1 Arrb2 Erk1 Erk2 F2 F2r F2rl2 F2rl3 Gna11 Gna14 Gna15 Gnaq Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Mapk Mapk1 Mapk3 Par1 Par3 Par4 Prkm1 Prkm3 Src
CS/DS degradation	Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase-1 Hyaluronidase-3 Iduronate 2-sulfatase Neurocan core protein Versican core protein (Fragments)	D3ZE16 F1LLW8 P47853 P50430 P55067 P55068 Q00657 Q01129 Q641X3 Q6AXR4 Q76HM9 Q76HN1 Q9ERB4 Q9ERQ6	Arsb Bcan Behab Bgn Caleb Cspg2 Cspg3 Cspg4 Cspg5 Dcn Hexa Hexb Hyal1 Hyal3 Ids Idua LOC100363795 Ncan Ng2 Ngc Vcan	G27025MB
Alpha-defensins	Alpha-defensin N-terminal domain-containing protein Anionic trypsin-2-like Anionic trypsin-2 Defensin alpha 10 Defensin alpha 11 Defensin alpha 24 Defensin alpha 4 Defensin alpha 6 Defensin alpha 8 Defensin alpha 9 Defensin alpha-like protein 1 NAD(P)(+)--arginine ADP-ribosyltransferase Neutrophil antibiotic peptide NP-2 Neutrophil antibiotic peptide NP-3B Serine protease 1 Similar to Anionic trypsin II precursor (Pretrypsinogen II) T-cell surface glycoprotein CD4 Trypsin 10 trypsin trypsin	A0A8I5Y5M6 A0A8I5ZME9 A0A8I6APH4 A0A8I6GLV0 D3ZJK0 D3ZQV0 F1LSU5 P00762 P00763 P05540 Q4JEI2 Q4JEI3 Q4JEI5 Q4JEI6 Q4JEI8 Q4JEI9 Q62714 Q62715 Q9Z1F1 W4VSR6	Art1 Cd4 Defa Defa-rs1 Defa10 Defa11 Defa24 Defa6 Defa8 Defa9 Defal1 Defcr4 ENSRNOG00000064390 LOC100365995 LOC102554637 LOC683849 Np4 Prss1 Prss2 Prss2l1 Prss3 Rd5 Trp1 Try1 Try10 Try2 Try4 Try5 Tryp1
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Artemin Docking protein 1 Docking protein 2 Docking protein 4 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha 3 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GDNF family receptor alpha-4 GRB2-associated binding protein 1 GRB2-associated-binding protein 2 Glial cell line-derived neurotrophic factor Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase 7 Neurturin PDZ and LIM domain protein 7 Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase Src Proto-oncogene tyrosine-protein kinase receptor Ret Rap1 GTPase-activating protein SH3 and multiple ankyrin repeat domains protein 3 SHC-transforming protein 1 SHC-transforming protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5Y949 A0A8I6A882 A0A8I6ALT5 A0A8I6B3J9 D3ZAL7 D4A244 D4A3T0 F1LV89 F1M038 F1MAL5 F7F1M3 F7FET5 G3V9H8 O70143 O70301 P05696 P0C865 P0CE43 P10686 P27791 P41499 P62994 P68182 Q07731 Q4QQV2 Q5M824 Q62997 Q63787 Q63788 Q63789 Q6AYE8 Q811Q5 Q9EPI2 Q9EQH1 Q9JLU4 Q9QZC5 Q9WUD9 Q9Z1L0 Q9Z1Z9	Artn Ash Bmk1 Dok1 Dok2 Dok4 Dok5 Dok6 Enigma Erk5 Frs2 Gab1 Gab2 Gdnf Gdnfra Gfra1 Gfra2 Gfra3 Gfra4 Grb10 Grb2 Grb7 Irs2 Lim1 Mapk7 Nrtn Nshc Pdlim7 Pik3ca Pik3cb Pik3cd Pik3r1 Pik3r2 Pik3r3 Pkacb Pkca Plcg1 Prkaca Prkacb Prkca Prosap2 Pspn Ptpn11 Rap1gap Ret Retl1 Shank3 Shc1 Shc3 Shcc Sos1 Src Trnr1
Neurotransmitter release cycle	N-acylethanolamine-hydrolyzing acid amidase	Q5KTC7	Asahl Naaa
Amino acid transport across the plasma membrane	Amino acid transporter heavy chain SLC3A1 Amino acid transporter heavy chain SLC3A2 Asc-type amino acid transporter 1 Cationic amino acid transporter 3 High affinity cationic amino acid transporter 1 Large neutral amino acids transporter small subunit 1 Large neutral amino acids transporter small subunit 2 Large neutral amino acids transporter small subunit 4 Mitochondrial basic amino acids transporter Monocarboxylate transporter 10 Neutral amino acid transporter B(0) Proton-coupled amino acid transporter 1 Proton-coupled amino acid transporter 2 Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent taurine transporter Sodium- and chloride-dependent transporter XTRP3 Sodium-coupled neutral amino acid symporter 1 Sodium-coupled neutral amino acid symporter 2 Sodium-coupled neutral amino acid transporter 3 Sodium-coupled neutral amino acid transporter 4 Sodium-coupled neutral amino acid transporter 5 Sodium-dependent neutral amino acid transporter B(0)AT1 Sodium-dependent neutral amino acid transporter B(0)AT2 Sodium-dependent neutral amino acid transporter B(0)AT3 Solute carrier family 36 member 4 Solute carrier family 43 member 1 Solute carrier family 7 member 11 Transporter Y+L amino acid transporter 1 Y+L amino acid transporter 2 b(0,+)-type amino acid transporter 1	A0A8I5ZKR1 A0A8I6A5L0 A0A8I6AB70 A0A8I6AUR9 A2VCW5 B1WBX5 D3ZJ25 D3ZMH7 O08812 P30823 P31643 P48056 P63116 P82252 Q08469 Q2A865 Q5HZE0 Q62687 Q63016 Q64093 Q64319 Q794F9 Q8K415 Q91Y77 Q924A5 Q9EQ25 Q9JHE5 Q9JHZ9 Q9JM15 Q9R0S5 Q9WVR6	Asc1 Ata1 Ata2 Ata3 Atrc1 Atrc3 B0at1 B0at3 Bat1 Cat3 Glnt Lat1 Lat2 Lat4 Lyaat1 Mct10 Mpe16 Nbat Ntt73 Ornt3 Pat2 Sa1 Sa2 Sat1 Sat2 Sit1 Slc16a10 Slc1a5 Slc25a29 Slc36a1 Slc36a2 Slc36a4 Slc38a1 Slc38a2 Slc38a3 Slc38a4 Slc38a5 Slc3a1 Slc3a2 Slc43a1 Slc43a2 Slc6a12 Slc6a14 Slc6a15 Slc6a18 Slc6a19 Slc6a20 Slc6a6 Slc7a1 Slc7a10 Slc7a11 Slc7a3 Slc7a5 Slc7a6 Slc7a7 Slc7a8 Slc7a9 Sn2 Snat1 Snat2 Snat3 Snat4 Snat5 Ta1 Tat1 Tramd1 Xtrp2 Xtrp3
Basigin interactions	Amino acid transporter heavy chain SLC3A2 Asc-type amino acid transporter 1 Basigin Caveolin-1 Integrin alpha 3 variant B Integrin beta-1 Integrin subunit alpha 6 Large neutral amino acids transporter small subunit 1 Large neutral amino acids transporter small subunit 2 Leukosialin (Fragment) Monocarboxylate transporter 1 Monocarboxylate transporter 3 Monocarboxylate transporter 4 Myelin-associated glycoprotein Neural cell adhesion molecule L1 Peptidyl-prolyl cis-trans isomerase A RING-type E3 ubiquitin transferase Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta-2 Sodium/potassium-transporting ATPase subunit beta-3 Solute carrier family 7 member 11 Y+L amino acid transporter 1 Y+L amino acid transporter 2 b(0,+)-type amino acid transporter 1 interstitial collagenase	A0A8I5ZKR1 A0A8I6AB70 A0A8I6AJE9 B5DFD5 F7FHL6 I4DUB5 O35910 O70461 P07340 P07722 P10111 P13638 P13838 P26453 P41350 P49134 P53987 P63116 P82252 Q05695 Q63016 Q63377 Q794F9 Q9R0S5 Q9WVR6	Asc1 Atp1b1 Atp1b2 Atp1b3 Bat1 Bsg Caml1 Cav Cav1 ITGA3B Itga3 Itga6 Itgb1 L1cam Lat1 Lat2 Lat4 Mag Mct1 Mct3 Mct4 Mmp1 Mmp1a Mpe16 Ppia Ppil2 Slc16a1 Slc16a3 Slc16a8 Slc3a2 Slc7a10 Slc7a11 Slc7a5 Slc7a6 Slc7a7 Slc7a8 Slc7a9 Spn Ta1
Asparagine N-linked glycosylation	Asialoglycoprotein receptor 1 Asialoglycoprotein receptor 2 Beta-1,4-N-acetyl-galactosaminyl transferase 2 Uromodulin	A0A8I6AAQ3 P02706 P08290 P27590	Asgr-1 Asgr-2 Asgr1 Asgr2 B4galnt2 Umod
DAP12 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Beta-2-microglobulin GRB2-related adaptor protein 2 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Killer cell lectin like receptor C1 Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 NKG2-D type II integral membrane protein Natural killer cells antigen CD94 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Proto-oncogene tyrosine-protein kinase LCK Ras-related C3 botulinum toxin substrate 1 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3	A0A0G2JUX8 A0A0G2K344 A0A0G2K6M9 A0A8I5ZPB5 A0A8J8YIH6 D3ZYG0 D3ZZ89 D4A3T0 O35778 O70215 O70601 P07151 P08644 P10686 P20171 P24135 P62994 Q01621 Q04970 Q3KR57 Q5M824 Q62844 Q63787 Q63788 Q64725 Q6RUV5 Q6X9T7 Q9Z1L0	Ash B2m Btk Cd94 Dap12 Fyn Grap2 Grb2 Hras Hras1 Klrc1 Klrd1 Klrk1 Kras Kras2 Lat Lck Lcp2 Nkg2d Nkrp2 Nras Pik3ca Pik3cb Pik3r1 Pik3r2 Plcg1 Plcg2 Rac Rac1 Shc1 Sos1 Syk Trem2 Tyrobp Vav2 Vav3
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Crk-like protein Cytoplasmic protein Cytoplasmic protein GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B (Fragment) Proto-oncogene tyrosine-protein kinase Src Rap guanine nucleotide exchange factor 1 Ras GTPase-activating protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription Tyrosine-protein phosphatase non-receptor type 11	A0A0G2JX93 A0A0G2K2M3 A0A0G2K344 B2RZ33 D4A3M8 D4A3T0 F1M8L9 P08644 P10686 P20171 P20786 P28576 P41499 P50904 P52631 P52632 P62994 Q04970 Q05028 Q05030 Q5U2U2 Q62771 Q63767 Q63768 Q63787 Q63788 Q9QZC5 Q9WUD9 Q9Z1L0	Ash Bcar1 Cas Crk Crkas Crkl Crko Grb2 Grb7 Hras Hras1 Kras Kras2 Mgf Nck1 Nck2 Nras Pdgfa Pdgfb Pdgfr Pdgfr1 Pdgfra Pdgfrb Pik3ca Pik3cb Pik3r1 Pik3r2 Plcg1 Ptpn11 Rapgef1 Rasa Rasa1 Rpa1 Sos1 Src Stat1 Stat3 Stat4 Stat5a Stat5b Stat6
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Growth factor receptor-bound protein 2 Neurotrophin-4 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A244 D4A3T0 P23363 P34131 P62994 Q63604	Ash Bdnf Frs2 Grb2 Nt4 Ntf4 Ntf5 Ntrk2 Sos1 Trkb
Spry regulation of FGF signaling	E3 ubiquitin-protein ligase CBL Growth factor receptor-bound protein 2 MAP kinase-interacting serine/threonine-protein kinase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Protein phosphatase 2 scaffold subunit A alpha Protein sprouty homolog 2 Proto-oncogene tyrosine-protein kinase Src Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein non-specific serine/threonine protein kinase	A0A8I6A5Y3 A0A8I6ATH0 A0A8I6G3R2 P0CG51 P21708 P41499 P62716 P62982 P62994 P63086 P63331 Q4G050 Q5HZA2 Q5XI34 Q63429 Q9WUD9	Ash Braf Cbl Erk1 Erk2 Grb2 LOC100360645 Mapk Mapk1 Mapk3 Mknk1 Mnk1 Ppp2ca Ppp2cb Ppp2r1a Prkm1 Prkm3 Ptpn11 Rps27a Spry2 Src Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
PI3K events in ERBB2 signaling	Betacellulin GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3	A0A0G2K344 A0A8I5Y1H8 A0A8I6AQ55 D3ZAL7 G3V6K6 O35569 P06494 P07522 P43322 P62994 Q06175 Q62799 Q63787 Q9Z0L5	Ash Btc Dtr Egf Egfr Erbb2 Erbb3 Ereg Gab1 Grb2 Hbegf Hegfl Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Pik3ca Pik3r1
GRB2 events in ERBB2 signaling	Betacellulin GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I5Y1H8 A0A8I6AQ55 D4A3T0 O35569 P06494 P08644 P20171 P43322 P62994 Q04970 Q06175 Q9Z0L5	Ash Btc Dtr Erbb2 Ereg Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Ndf Neu Nras Nrg1 Nrg2 Nrg3 Ntak Sos1
SHC1 events in ERBB4 signaling	Betacellulin GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I5Y1H8 A0A8I6AQ55 D4A3T0 O35569 P08644 P20171 P43322 P62994 Q04970 Q06175 Q5M824 Q9Z0L5	Ash Btc Dtr Ereg Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Ndf Nras Nrg1 Nrg2 Nrg3 Ntak Shc1 Sos1
Regulation of signaling by CBL	Adapter molecule crk Crk-like protein E3 ubiquitin-protein ligase CBL Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Proto-oncogene vav Rap guanine nucleotide exchange factor 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5Y949 A0A8I6G3R2 F1LM93 F1M8L9 P50545 P54100 P62994 Q07014 Q5U2U2 Q62844 Q63768 Q63787 Q63788 Q63789 Q64725 Q9Z1L0	Ash Cbl Crk Crkl Crko Fyn Grb2 Hck Lyn Pik3ca Pik3cb Pik3cd Pik3r1 Pik3r2 Pik3r3 Rapgef1 Syk Vav Vav1 Yes1
Negative regulation of MET activity	E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor pathway substrate 15 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor-regulated tyrosine kinase substrate Hepatocyte growth factor Leucine-rich repeats and immunoglobulin-like domains 1 Polyubiquitin-B Polyubiquitin-C SH3 domain-containing kinase-binding protein 1 Signal transducing adapter molecule 2 Signal transducing adaptor molecule Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase ubiquitinyl hydrolase 1	A0A8I5YC99 A0A8I6A5Y3 A0A8I6G3R2 A0A8I6GK94 B5DF55 D3ZN39 M0RB60 O35179 O35180 O35964 P0CG51 P17945 P20417 P35233 P62982 P62994 P97523 Q5XHY7 Q63429 Q925Q9 Q9JJ50	Ash Cbl Eps15 Grb2 Hgf Hgs Hrs Hrs2 LOC100360645 Lrig1 Met Ptpn1 Ptpn2 Ptprj Rps27a Ruk Seta Sh3d2a Sh3d2c1 Sh3gl1 Sh3gl2 Sh3gl3 Sh3kbp1 Sh3p13 Sh3p4 Sh3p8 Stam Stam2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Usp8
Negative regulation of FGFR4 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Klotho beta Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I6A5Y3 A0A8I6B5D5 A0A8I6G3R2 D3Z8T6 D4A244 F1LSQ8 O54769 O88182 P0CG51 P13109 P21708 P36364 P41499 P61149 P62982 P62994 P63076 P63086 Q498D6 Q63429 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	Ash Cbl Erk1 Erk2 FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Frs2 Grb2 Klb LOC100360645 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Ptpn11 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
Negative regulation of FGFR2 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I6A5Y3 A0A8I6B5D5 A0A8I6G3R2 D4A244 F1LSG7 F1LSQ8 O54769 O88182 P0CG51 P13109 P21708 P36364 P41499 P48807 P61149 P62982 P62994 P63076 P63086 P70492 Q02195 Q63429 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9	Ash Cbl Erk1 Erk2 FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-7 Fgf-9 Fgf1 Fgf10 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr2 Frs2 Grb2 Kgf LOC100360645 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Ptpn11 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
Negative regulation of FGFR1 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Klotho Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I6A5Y3 A0A8I6B5D5 A0A8I6G3R2 D4A244 F1LSQ8 P0CG51 P13109 P21708 P36364 P41499 P48807 P61149 P62982 P62994 P63076 P63086 P70492 Q04589 Q63429 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9 Q9Z2Y9	Ash Cbl Erk1 Erk2 FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf10 Fgf17 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Frs2 Grb2 Kl LOC100360645 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Ptpn11 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
Negative regulation of FGFR3 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2K210 A0A8I6A5Y3 A0A8I6B5D5 A0A8I6G3R2 D4A244 F1LSQ8 O54769 O88182 P0CG51 P13109 P21708 P36364 P41499 P48807 P61149 P62982 P62994 P63076 P63086 Q63429 Q8VI82 Q9EST9	Ash Cbl Erk1 Erk2 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3 Frs2 Grb2 LOC100360645 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Ptpn11 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
CD28 dependent Vav1 pathway	CD86 molecule Cd80 molecule Cell division control protein 42 homolog Growth factor receptor-bound protein 2 Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 T-cell-specific surface glycoprotein CD28 Tyrosine-protein kinase Fyn	G3V671 O35531 P31042 P35465 P54100 P62994 Q01621 Q62829 Q62844 Q64303 Q6RUV5 Q8CFN2	Ash Cd28 Cd80 Cd86 Cdc42 Fyn Grb2 Lck Pak1 Pak2 Pak3 Rac Rac1 Vav Vav1

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