GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1601 - 1625** of **2090** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol
Processing of DNA double-strand break ends	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 Claspin Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF4 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 NAD-dependent protein deacylase sirtuin-6 Nibrin Polyubiquitin-B Polyubiquitin-C Protein timeless homolog RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein phosphatase 4 catalytic subunit Serine/threonine-protein phosphatase 4 regulatory subunit 2 Small ubiquitin-related modifier 2 TIMELESS-interacting protein TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14757 O60671 O60814 O60921 O60934 O75943 O76064 O95714 O96028 P06899 P0CG47 P0CG48 P15927 P16104 P20248 P23527 P24941 P27694 P33778 P35244 P35249 P35250 P38398 P40937 P40938 P46736 P49959 P51530 P54132 P57053 P58876 P60510 P61088 P61956 P62805 P62807 P62979 P62987 P63279 P78317 P78396 Q12888 Q13315 Q13472 Q13535 Q14191 Q14676 Q15819 Q16695 Q16778 Q6UWZ7 Q6WBX8 Q8IYW5 Q8N257 Q8N2W9 Q8N6T7 Q8WXE1 Q92547 Q92878 Q92993 Q93079 Q96A08 Q96E14 Q96RL1 Q99638 Q99708 Q99728 Q99877 Q99879 Q99880 Q9BSD3 Q9BVW5 Q9BX63 Q9H9A7 Q9HAW4 Q9NWV8 Q9NXR7 Q9NY27 Q9UNS1 Q9UQ84	ABRA1 ABRAXAS1 AGS1 ATM ATR ATRIP BABAM1 BABAM2 BACH1 BARD1 BLM BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE BRIP1 C12orf32 C16orf75 C19orf62 C6.1A C9orf76 CCDC98 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 CHEK1 CHK1 CLSPN CTIP CXorf53 DNA2 DNA2L EXO1 EXOI FAM175A FANCJ FRP1 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HEX1 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0170 KIAA0259 KIAA0646 KIAA1090 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NSD2 P95 PIAS4 PIASG PPP4 PPP4C PPP4R2 PPX R24L RAD1 RAD17 RAD50 RAD9A RAD9B RAP80 RBBP8 REC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF168 RNF4 RNF53 RNF8 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A RXRIP110 SIR2L6 SIRT6 SMT3B SMT3H2 SNURF SUMO2 TIM TIM1 TIMELESS TIMELESS1 TIP60 TIPIN TOP3 TOP3A TOPBP1 TP53BP1 TRX5 TSH2B UBA52 UBA80 UBB UBC UBC9 UBCE9 UBCEP1 UBCEP2 UBE2I UBE2N UBE2V2 UEV2 UIMC1 WHSC1 WRN
G2/M DNA damage checkpoint	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Cellular tumor antigen p53 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2	O14757 O60671 O60814 O60921 O60934 O75943 O76064 O95714 O96017 O96028 P04637 P06899 P15927 P16104 P23527 P27694 P33778 P35244 P35249 P35250 P38398 P40937 P40938 P46736 P49959 P51530 P54132 P57053 P58876 P61088 P62805 P62807 Q12888 Q13315 Q13472 Q13535 Q14191 Q14676 Q15819 Q16695 Q16778 Q6UWZ7 Q6WBX8 Q8IYW5 Q8N257 Q8N2W9 Q8WXE1 Q92547 Q92878 Q92993 Q93079 Q96A08 Q96E14 Q96RL1 Q99638 Q99708 Q99728 Q99877 Q99879 Q99880 Q9BSD3 Q9BX63 Q9H9A7 Q9NWV8 Q9NXR7 Q9UQ84	ABRA1 ABRAXAS1 AGS1 ATM ATR ATRIP BABAM1 BABAM2 BACH1 BARD1 BLM BLU BRCA1 BRCC3 BRCC36 BRCC45 BRE BRIP1 C12orf32 C16orf75 C19orf62 C6.1A C9orf76 CCDC98 CDS1 CHEK1 CHEK2 CHK1 CHK2 CTIP CXorf53 DNA2 DNA2L EXO1 EXOI FAM175A FANCJ FRP1 H2AFX H2AX H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HERC2 HEX1 HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0170 KIAA0259 KIAA0646 KIAA1090 MDC1 MERIT40 MMS2 MMSET MRE11 MRE11A NBA1 NBN NBS NBS1 NFBD1 NSD2 P53 P95 PIAS4 PIASG R24L RAD1 RAD17 RAD50 RAD53 RAD9A RAD9B RAP80 RBBP8 REC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF168 RNF53 RNF8 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RXRIP110 TIP60 TOP3 TOP3A TOPBP1 TP53 TP53BP1 TRX5 TSH2B UBE2N UBE2V2 UEV2 UIMC1 WHSC1 WRN
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family AAA domain-containing protein 2 Choriogonadotropin subunit beta 3 Epidermal growth factor receptor Estrogen receptor Glycoprotein hormones alpha chain Mast/stem cell growth factor receptor Kit Protransforming growth factor alpha Receptor tyrosine-protein kinase erbB-2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcriptional repressor protein YY1 Vascular endothelial growth factor A, long form	P00533 P01135 P01215 P03372 P04626 P05549 P0DN86 P10721 P15692 P25490 Q6PL18 Q92481 Q92754	AP2TF ATAD2 CGA CGB CGB3 CGB5 CGB8 EGFR ERBB ERBB1 ERBB2 ESR ESR1 HER1 HER2 INO80S KIT MLN19 NEU NGL NR3A1 SCFR TFAP2 TFAP2A TFAP2B TFAP2C TGFA VEGF VEGFA YY1
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	ATPase GET3 Amyloid-beta precursor protein Emerin Golgi to ER traffic protein 4 homolog Guided entry of tail-anchored proteins factor 1 Guided entry of tail-anchored proteins factor CAMLG Heme oxygenase 1 Large proline-rich protein BAG6 Major prion protein Otoferlin Protein transport protein Sec61 subunit beta Protein transport protein Sec61 subunit gamma Small glutamine-rich tetratricopeptide repeat-containing protein alpha Stress-associated endoplasmic reticulum protein 1 Syntaxin-1A Syntaxin-5 Ubiquitin-like protein 4A Vesicle-associated membrane protein 2 Vesicle-associated membrane protein-associated protein A	O00258 O43681 O43765 P04156 P05067 P09601 P11441 P46379 P49069 P50402 P60059 P60468 P63027 Q13190 Q16623 Q7L5D6 Q9HC10 Q9P0L0 Q9Y6X1	A4 AD1 ALTPRP APP ARSA ASNA1 BAG6 BAT3 C7orf20 CAML CAMLG CEE CHD5 DXS254E EDMD EMD FER1L2 G3 GDX GET1 GET2 GET3 GET4 HMOX1 HO HO1 OTOF PRIP PRNP PRP RAMP4 SEC61B SEC61G SERP1 SGT SGT1 SGTA STA STX1 STX1A STX5 STX5A SYB2 TRC35 TRC40 UBL4 UBL4A VAMP2 VAP33 VAPA WRB
Classical Kir channels	ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 14 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	P48050 P63252 Q14500 Q9UNX9	IRK1 IRK2 IRK3 IRK4 KCNJ12 KCNJ14 KCNJ2 KCNJ4 KCNJN1
Phase 4 - resting membrane potential	ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 14 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4 Potassium channel subfamily K member 10 Potassium channel subfamily K member 12 Potassium channel subfamily K member 13 Potassium channel subfamily K member 15 Potassium channel subfamily K member 16 Potassium channel subfamily K member 17 Potassium channel subfamily K member 18 Potassium channel subfamily K member 1 Potassium channel subfamily K member 2 Potassium channel subfamily K member 3 Potassium channel subfamily K member 4 Potassium channel subfamily K member 5 Potassium channel subfamily K member 6 Potassium channel subfamily K member 7 Potassium channel subfamily K member 9	O00180 O14649 O95069 O95279 P48050 P57789 P63252 Q14500 Q7Z418 Q96T54 Q96T55 Q9H427 Q9HB14 Q9HB15 Q9NPC2 Q9NYG8 Q9UNX9 Q9Y257 Q9Y2U2	HOHO1 IRK1 IRK2 IRK3 IRK4 KCNJ12 KCNJ14 KCNJ2 KCNJ4 KCNJN1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK18 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNO1 TALK1 TALK2 TASK TASK1 TASK2 TASK3 TASK4 TASK5 TOSS TRAAK TREK TREK1 TREK2 TRESK TRIK TWIK1 TWIK2
Activation of G protein gated Potassium channels	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	O14610 O14775 O60262 O75899 P16520 P48050 P48051 P48544 P48549 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P63252 P78508 Q14500 Q92806 Q99712 Q9HAV0 Q9NPI9 Q9P2W3 Q9UBI6 Q9UBS5 Q9UK08	GABBR1 GABBR2 GIRK1 GIRK2 GIRK3 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPR51 GPRC3A GPRC3B IRK1 IRK2 IRK3 KATP2 KCNJ10 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ7 KCNJ9 KCNJN1
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	O14610 O14775 O60262 O75899 P16520 P48050 P48051 P48544 P48549 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P63252 P78508 Q14500 Q92806 Q99712 Q9HAV0 Q9NPI9 Q9P2W3 Q9UBI6 Q9UBS5 Q9UK08	GABBR1 GABBR2 GIRK1 GIRK2 GIRK3 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPR51 GPRC3A GPRC3B IRK1 IRK2 IRK3 KATP2 KCNJ10 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ7 KCNJ9 KCNJN1
Potassium transport channels	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 1 Inward rectifier potassium channel 16	P48048 P78508 Q9NPI9	KCNJ1 KCNJ10 KCNJ16 ROMK1
Cellular response to mitochondrial stress	ATP-dependent zinc metalloprotease YME1L1 DAP3-binding cell death enhancer 1 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 2-alpha kinase 1 Metalloendopeptidase OMA1, mitochondrial Prohibitin-2 Stomatin-like protein 2, mitochondrial	P05198 P20042 P41091 Q14154 Q96E52 Q96TA2 Q99623 Q9BQI3 Q9UJZ1	BAP DELE DELE1 EIF2A EIF2AK1 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 FTSH1 HRI KIAA0141 KIAA1369 MPRP1 OMA1 PHB2 REA SLP2 STOML2 YME1L YME1L1
Processing of SMDT1	ATP-dependent zinc metalloprotease YME1L1 Calcium uniporter protein, mitochondrial Calcium uniporter regulatory subunit MCUb, mitochondrial Calcium uptake protein 1, mitochondrial Calcium uptake protein 2, mitochondrial Calcium uptake protein 3, mitochondrial Essential MCU regulator, mitochondrial Mitochondrial inner membrane m-AAA protease component AFG3L2 Mitochondrial inner membrane m-AAA protease component paraplegin Mitochondrial-processing peptidase subunit alpha Mitochondrial-processing peptidase subunit beta Presenilin-associated rhomboid-like protein, mitochondrial Prohibitin 1 Prohibitin-2 Stomatin-like protein 2, mitochondrial m-AAA protease-interacting protein 1, mitochondrial	O75439 P35232 Q10713 Q86XE3 Q8IYU8 Q8NE86 Q8WWC4 Q96TA2 Q99623 Q9BPX6 Q9H300 Q9H4I9 Q9NWR8 Q9UJZ1 Q9UQ90 Q9Y4W6	AFG3L2 BAP C10orf42 C22orf32 C2orf47 CALC CAR CBARA1 CCDC109A CCDC109B CMAR EFHA1 EFHA2 EMRE FTSH1 INPP5E KIAA0123 MAIP1 MCU MCUB MICU1 MICU2 MICU3 MPPA MPPB PARL PGN PHB PHB1 PHB2 PMPCA PMPCB PSARL REA SLP2 SMDT1 SPG7 STOML2 YME1L YME1L1
Abacavir transmembrane transport	ATP-dependent translocase ABCB1 Broad substrate specificity ATP-binding cassette transporter ABCG2 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	O15244 O15245 O75751 P08183 Q9UNQ0	ABCB1 ABCG2 ABCP BCRP BCRP1 EMTH MDR1 MXR OCT1 OCT2 OCT3 PGY1 SLC22A1 SLC22A2 SLC22A3
PIWI-interacting RNA (piRNA) biogenesis	ATP-dependent RNA helicase TDRD9 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Heat shock protein HSP 90-alpha Inactive peptidyl-prolyl cis-trans isomerase FKBP6 Mitochondrial cardiolipin hydrolase Myb-related protein A Piwi-like protein 1 Piwi-like protein 2 Piwi-like protein 4 Probable ATP-dependent RNA helicase DDX4 Protein maelstrom homolog Putative ATP-dependent RNA helicase TDRD12 RNA helicase Mov10l1 Small RNA 2'-O-methyltransferase Tudor and KH domain-containing protein Tudor domain-containing protein 1 Tudor domain-containing protein 6	O15514 O60522 O75344 P07900 P10243 P19387 P19388 P24928 P30876 P36954 P52434 P52435 P53803 P61218 P62487 P62875 Q587J7 Q5T8I9 Q7Z3Z4 Q8N2A8 Q8NDG6 Q8TC59 Q8WWH4 Q96J94 Q96JY0 Q9BXT4 Q9BXT6 Q9NQI0 Q9Y2W6	ALP1 AMYB ANKL1 ASZ1 C14orf75 C1orf59 C7orf7 DDX4 ECAT8 FKBP36 FKBP6 GASZ HENMT1 HILI HIWI HIWI2 HSP90A HSP90AA1 HSPC1 HSPCA MAEL MOV10L1 MYBL1 PIWI PIWIL1 PIWIL2 PIWIL4 PLD6 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RPB7 TDRD1 TDRD12 TDRD2 TDRD6 TDRD9 TDRKH VASA
Mitochondrial RNA degradation	ATP-dependent RNA helicase SUPV3L1, mitochondrial G-rich sequence factor 1 Leucine-rich PPR motif-containing protein, mitochondrial Oligoribonuclease, mitochondrial Polyribonucleotide nucleotidyltransferase 1, mitochondrial SRA stem-loop-interacting RNA-binding protein, mitochondrial	P42704 Q12849 Q8IYB8 Q8TCS8 Q9GZT3 Q9Y3B8	C14orf156 GRSF1 LRP130 LRPPRC PNPASE PNPT1 REXO2 SFN SLIRP SMFN SUPV3L1 SUV3
DDX58/IFIH1-mediated induction of interferon-alpha/beta	ATP-dependent RNA helicase DHX58 Antiviral innate immune response receptor RIG-I E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Mitochondrial import receptor subunit TOM70 NLR family member X1 Nucleoprotein ORF9b protein Protein NLRC5 Serine/threonine-protein kinase TBK1 Triokinase/FMN cyclase Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ISG15 Ubiquitin/ISG15-conjugating enzyme E2 L6	O14933 O94826 O95786 P05161 P07900 P08238 P0DTC9 P0DTD2 P41226 Q14258 Q14653 Q3LXA3 Q7Z434 Q86UT6 Q86WI3 Q8IUD6 Q96C10 Q9BYX4 Q9C037 Q9UHD2 Q9UII4	9b CEB1 CEBP1 D11LGP2E DAK DDX58 DHX58 EFP G1P2 HERC5 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB IFIH1 IPS1 IRF3 ISG15 KIAA0719 KIAA1271 LGP2 MAVS MDA5 N NAK NLRC5 NLRX1 NOD27 NOD4 NOD5 NOD9 RH116 RIGI RNF135 RNF147 RNF87 TBK1 TKFC TOM70 TOMM70 TOMM70A TRIM25 TRIM4 UBA7 UBCH8 UBE1L UBE2 UBE2L6 UCRP VISA ZNF147
mRNA 3'-end processing	ATP-dependent RNA helicase DDX39A Chromatin target of PRMT1 protein Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 Eukaryotic initiation factor 4A-III Leucine zipper protein 4 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Polyadenylate-binding protein 2 Polymerase delta-interacting protein 3 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Pre-mRNA-processing factor 17 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor SLU7 Protein CASC3 Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SAP domain-containing ribonucleoprotein Serine/arginine repetitive matrix protein 1 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 9 Spliceosome RNA helicase DDX39B Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Symplekin THO complex subunit 1 THO complex subunit 2 THO complex subunit 3 THO complex subunit 4 THO complex subunit 5 homolog THO complex subunit 6 homolog THO complex subunit 7 homolog UAP56-interacting factor Zinc finger CCCH domain-containing protein 11A pre-mRNA 3' end processing protein WDR33	O00148 O15234 O43809 O60508 O75152 O94913 O95391 O95639 P26368 P33240 P38919 P51003 P52298 P61326 P82979 P84103 Q01081 Q01130 Q05048 Q05519 Q07955 Q08170 Q09161 Q10570 Q12996 Q13242 Q13243 Q13247 Q13769 Q13838 Q15287 Q16629 Q6I9Y2 Q6UN15 Q86U42 Q86V81 Q86W42 Q8IYB3 Q8N684 Q8NI27 Q8WU68 Q92620 Q92797 Q92989 Q96A72 Q96FV9 Q96J01 Q96QD9 Q9BY77 Q9BZI7 Q9C0J8 Q9H0L4 Q9P127 Q9P2I0 Q9UKF6 Q9Y3Y2 Q9Y5S9	ALY ALYREF ASF BAT1 BEF C1orf77 C22orf19 CASC3 CBP20 CBP80 CDC40 CFIM25 CHTOP CLP1 CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 CXorf3 DDX38 DDX39 DDX39A DDX39B DDX48 DHX38 EHB3 EIF4A3 FIP1 FIP1L1 FOP FYTTD1 HCC1 HEAB HPR1 HRS KIAA0111 KIAA0224 KIAA0663 KIAA0689 KIAA0824 KIAA0983 KIAA1367 KIAA1649 LDC2 LUZP4 MAGOH MAGOH2 MAGOHA MAGOHB MLN51 NAR NCBP NCBP1 NCBP2 NEB1 NIF3L1BP1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PCF11 PDIP46 POLDIP3 PRP16 PRP17 PRPF17 RBM8 RBM8A RENT3B RHE RNPS1 SARNP SF2 SF2P33 SFRS1 SFRS11 SFRS2 SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SLU7 SPK SRM160 SRP20 SRP30C SRP40 SRP55 SRP75 SRRM1 SRSF1 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF9 SYMPK THOC1 THOC2 THOC3 THOC4 THOC5 THOC6 THOC7 U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP UAP56 UIF UPF3B UPF3X WDC146 WDR33 WDR58 ZC3H11A ZC3HDC11A
RNA Polymerase II Transcription Termination	ATP-dependent RNA helicase DDX39A Chromatin target of PRMT1 protein Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 Eukaryotic initiation factor 4A-III Histone RNA hairpin-binding protein Leucine zipper protein 4 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Polyadenylate-binding protein 2 Polymerase delta-interacting protein 3 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Pre-mRNA-processing factor 17 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor SLU7 Protein CASC3 Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SAP domain-containing ribonucleoprotein Serine/arginine repetitive matrix protein 1 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 9 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' Spliceosome RNA helicase DDX39B Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Symplekin THO complex subunit 1 THO complex subunit 2 THO complex subunit 3 THO complex subunit 4 THO complex subunit 5 homolog THO complex subunit 6 homolog THO complex subunit 7 homolog U7 snRNA-associated Sm-like protein LSm10 U7 snRNA-associated Sm-like protein LSm11 UAP56-interacting factor Zinc finger CCCH domain-containing protein 11A Zinc finger protein 473 pre-mRNA 3' end processing protein WDR33	O00148 O15234 O43809 O60508 O75152 O94913 O95391 O95639 P14678 P26368 P33240 P38919 P51003 P52298 P61326 P62304 P62306 P62308 P62318 P82979 P83369 P84103 Q01081 Q01130 Q05048 Q05519 Q07955 Q08170 Q09161 Q10570 Q12996 Q13242 Q13243 Q13247 Q13769 Q13838 Q14493 Q15287 Q16629 Q6I9Y2 Q6UN15 Q86U42 Q86V81 Q86W42 Q8IYB3 Q8N684 Q8NI27 Q8WTR7 Q8WU68 Q92620 Q92797 Q92989 Q969L4 Q96A72 Q96FV9 Q96J01 Q96QD9 Q9BY77 Q9BZI7 Q9C0J8 Q9H0L4 Q9P127 Q9P2I0 Q9UKF6 Q9Y3Y2 Q9Y5S9	ALY ALYREF ASF BAT1 BEF C1orf77 C22orf19 CASC3 CBP20 CBP80 CDC40 CFIM25 CHTOP CLP1 COD CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 CXorf3 DDX38 DDX39 DDX39A DDX39B DDX48 DHX38 EHB3 EIF4A3 FIP1 FIP1L1 FOP FYTTD1 HBP HCC1 HEAB HPR1 HRS KIAA0111 KIAA0224 KIAA0663 KIAA0689 KIAA0824 KIAA0983 KIAA1141 KIAA1367 KIAA1649 LDC2 LSM10 LSM11 LUZP4 MAGOH MAGOH2 MAGOHA MAGOHB MLN51 NAR NCBP NCBP1 NCBP2 NEB1 NIF3L1BP1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PBSCF PBSCG PCF11 PDIP46 POLDIP3 PRP16 PRP17 PRPF17 RBM8 RBM8A RENT3B RHE RNPS1 SARNP SF2 SF2P33 SFRS1 SFRS11 SFRS2 SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SLBP SLU7 SNRPB SNRPB1 SNRPD3 SNRPE SNRPF SNRPG SPK SRM160 SRP20 SRP30C SRP40 SRP55 SRP75 SRRM1 SRSF1 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF9 SYMPK THOC1 THOC2 THOC3 THOC4 THOC5 THOC6 THOC7 U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP UAP56 UIF UPF3B UPF3X WDC146 WDR33 WDR58 ZC3H11A ZC3HDC11A ZFP100 ZNF473
Transport of Mature mRNA derived from an Intron-Containing Transcript	ATP-dependent RNA helicase DDX39A Aladin Chromatin target of PRMT1 protein E3 SUMO-protein ligase RanBP2 Eukaryotic initiation factor 4A-III Leucine zipper protein 4 NTF2-related export protein 1 Nuclear RNA export factor 1 Nuclear RNA export factor 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Polymerase delta-interacting protein 3 Pre-mRNA-processing factor 17 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor SLU7 Protein CASC3 Protein SEC13 homolog Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SAP domain-containing ribonucleoprotein Serine/arginine repetitive matrix protein 1 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 9 Spliceosome RNA helicase DDX39B Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit THO complex subunit 1 THO complex subunit 2 THO complex subunit 3 THO complex subunit 4 THO complex subunit 5 homolog THO complex subunit 6 homolog THO complex subunit 7 homolog UAP56-interacting factor Zinc finger CCCH domain-containing protein 11A mRNA export factor GLE1 mRNA export factor RAE1	A8CG34 O00148 O15234 O15504 O60508 O75152 O75694 O95391 P12270 P26368 P35658 P37198 P38919 P49790 P49792 P52298 P55735 P57740 P61326 P78406 P82979 P84103 Q01081 Q01130 Q05519 Q07955 Q08170 Q09161 Q12769 Q13242 Q13243 Q13247 Q13769 Q13838 Q15287 Q16629 Q53GS7 Q5SRE5 Q6I9Y2 Q7Z3B4 Q86V81 Q86W42 Q8IYB3 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8NI27 Q8TEM1 Q8WU68 Q8WUM0 Q92620 Q92621 Q96A72 Q96FV9 Q96HA1 Q96J01 Q96QD9 Q99567 Q9BTX1 Q9BW27 Q9BY77 Q9BZI7 Q9GZY0 Q9NRG9 Q9P127 Q9UBU9 Q9UKK6 Q9UKX7 Q9Y3Y2 Q9Y5S9	AAAS ADRACALA ALY ALYREF ASF BAT1 BEF C1orf77 C22orf19 C7orf14 CAIN CAN CASC3 CBP20 CBP80 CDC40 CG1 CHTOP CXorf3 D3S1231E DDX38 DDX39 DDX39A DDX39B DDX48 DHX38 EHB3 EIF4A3 FOP FYTTD1 GLE1 GLE1L HCC1 HPR1 HRS KIAA0023 KIAA0095 KIAA0111 KIAA0169 KIAA0197 KIAA0224 KIAA0225 KIAA0618 KIAA0663 KIAA0791 KIAA0906 KIAA0983 KIAA1649 LDC2 LUZP4 MAGOH MAGOH2 MAGOHA MAGOHB MLN51 MP44 MRNP41 NCBP NCBP1 NCBP2 NDC1 NIF3L1BP1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 NXF1 NXF2 NXF2B NXT1 PCNT1 PDIP46 POLDIP3 POM121 POM121A POM121C PRP16 PRP17 PRPF17 RAE1 RANBP2 RBM8 RBM8A RENT3B RNPS1 SARNP SEC13 SEC13A SEC13L1 SEC13R SF2 SF2P33 SFRS1 SFRS11 SFRS2 SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SLU7 SRM160 SRP20 SRP30C SRP40 SRP55 SRP75 SRRM1 SRSF1 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF9 TAP TAPL2 THOC1 THOC2 THOC3 THOC4 THOC5 THOC6 THOC7 TMEM48 TPR U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP UAP56 UIF UPF3B UPF3X WDR58 ZC3H11A ZC3HDC11A
tRNA processing in the nucleus	ATP-dependent RNA helicase DDX1 Aladin Ashwin CCA tRNA nucleotidyltransferase 1, mitochondrial Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 4 Cleavage stimulation factor subunit 2 E3 SUMO-protein ligase RanBP2 Exportin-T GTP-binding nuclear protein Ran Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Polyribonucleotide 5'-hydroxyl-kinase Clp1 Protein FAM98B Protein SEC13 homolog Protein archease RNA transcription, translation and transport factor protein RNA-splicing ligase RtcB homolog Ribonuclease P protein subunit p14 Ribonuclease P protein subunit p20 Ribonuclease P protein subunit p21 Ribonuclease P protein subunit p25 Ribonuclease P protein subunit p29 Ribonuclease P protein subunit p30 Ribonuclease P protein subunit p38 Ribonuclease P protein subunit p40 Ribonuclease P/MRP protein subunit POP5 Ribonucleases P/MRP protein subunit POP1 Zinc phosphodiesterase ELAC protein 2 mRNA export factor RAE1 tRNA-splicing endonuclease subunit Sen15 tRNA-splicing endonuclease subunit Sen2 tRNA-splicing endonuclease subunit Sen34 tRNA-splicing endonuclease subunit Sen54	A8CG34 O15504 O43592 O75694 O75817 O75818 O95059 O95639 O95707 P12270 P33240 P35658 P37198 P49790 P49792 P55735 P57740 P62826 P78345 P78346 P78406 Q10570 Q12769 Q52LJ0 Q5SRE5 Q7Z3B4 Q7Z6J9 Q8IWT0 Q8N1F7 Q8NCE0 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q8WW01 Q92499 Q92621 Q92989 Q969H6 Q96HA1 Q96Q11 Q99567 Q99575 Q9BQ52 Q9BSV6 Q9BTX1 Q9BUL9 Q9BVC5 Q9BW27 Q9H633 Q9NRG9 Q9UKX7 Q9Y224 Q9Y3I0	AAAS ADRACALA ARA24 ARCH C14orf166 C1orf19 C22orf28 C2orf49 C6orf135 C7orf14 CAIN CAN CAT60 CG1 CLP1 CPSF1 CPSF160 CPSF30 CPSF4 CSTF2 D3S1231E DDX1 ELAC2 FAM98B HEAB HPC2 KIAA0023 KIAA0061 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 LENG5 MP44 MRNP41 NAR NDC1 NEB1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C POP1 POP4 POP5 POP7 RAE1 RAN RANBP2 RNASEP1 RNASEP2 RPP14 RPP20 RPP21 RPP25 RPP29 RPP30 RPP38 RPP40 RTCB RTRAF SEC13 SEC13A SEC13L1 SEC13R SEN15 SEN2 SEN34 SEN54 TMEM48 TPR TRNT1 TSEN15 TSEN2 TSEN34 TSEN54 XPOT ZBTB8OS
RIP-mediated NFkB activation via ZBP1	ATP-dependent RNA helicase A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor-interacting Ras-like protein 1 NF-kappa-B inhibitor-interacting Ras-like protein 2 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 Toll-like receptor 3 Transcription factor p65 Z-DNA-binding protein 1	O14920 O15111 O15455 P19838 P25963 Q00653 Q04206 Q08211 Q13546 Q15653 Q8IUC6 Q99836 Q9H171 Q9NYR9 Q9NYS0 Q9Y572 Q9Y6K9	C20orf183 CHUK DDX9 DHX9 DLM1 FIP3 IKBA IKBB IKBKB IKBKG IKKA IKKB KBRAS1 KBRAS2 LKP LYT10 MAD3 MYD88 NDH2 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA NFKBIB NKIRAS1 NKIRAS2 PRVTIRB RELA RIP RIP1 RIP3 RIPK1 RIPK3 TCF16 TICAM1 TLR3 TRIF TRIP9 ZBP1
PKR-mediated signaling	ATP-dependent RNA helicase A Alpha-synuclein Cellular tumor antigen p53 Centromere protein S Centromere protein X Cyclin-dependent kinase 1 DnaJ homolog subfamily C member 3 Double-stranded RNA-specific adenosine deaminase Dual specificity mitogen-activated protein kinase kinase 6 E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase ARIH1 E3 ubiquitin-protein ligase FANCL E3 ubiquitin/ISG15 ligase TRIM25 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Fanconi anemia core complex-associated protein 100 Fanconi anemia core complex-associated protein 20 Fanconi anemia core complex-associated protein 24 Fanconi anemia group A protein Fanconi anemia group B protein Fanconi anemia group C protein Fanconi anemia group E protein Fanconi anemia group F protein Fanconi anemia group G protein Fanconi anemia group M protein Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock-related 70 kDa protein 2 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced, double-stranded RNA-activated protein kinase Interferon-inducible double-stranded RNA-dependent protein kinase activator A Interleukin enhancer-binding factor 2 Interleukin enhancer-binding factor 3 Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator Non-structural protein 1 Nucleophosmin Nucleoprotein Protein TRS1 Protein Tat RISC-loading complex subunit TARBP2 SH2/SH3 adapter protein NCK1 SUMO-conjugating enzyme UBC9 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Small ubiquitin-related modifier 1 Sphingosine kinase 1 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin-like protein ISG15 Ubiquitin/ISG15-conjugating enzyme E2 L6 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like	A8MT69 O14920 O14933 O15111 O15287 O15360 O75569 P03418 P03496 P04609 P04637 P05161 P05198 P06493 P06748 P0DMV8 P0DMV9 P11142 P16333 P17706 P19525 P20042 P30153 P30154 P34931 P37840 P40763 P41091 P42224 P52564 P54652 P55265 P62714 P63165 P63279 P67775 Q00597 Q08211 Q0VG06 Q12905 Q12906 Q13217 Q14258 Q15172 Q15633 Q6NZ36 Q6SVX2 Q7Z434 Q8IYD8 Q8N2Z9 Q8NB91 Q9BTP7 Q9HB96 Q9NPI8 Q9NW38 Q9NX74 Q9NYA1 Q9UII4 Q9Y4X5 Q9Y6K9	ADAR ADAR1 APITD1 APRF ARI ARIH1 C17orf70 C19orf40 C1orf86 CDC2 CDC28A CDK1 CDKN1 CEB1 CEBP1 CENPS CENPX CHUK DDX9 DHX9 DNAJC3 DRBF DSRAD DUS2 DUS2L EFP EIF2A EIF2AK2 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 FAA FAAP10 FAAP100 FAAP16 FAAP20 FAAP24 FAC FACA FACC FACE FANCA FANCB FANCC FANCE FANCF FANCG FANCH FANCL FANCM FIP3 G1P1 G1P2 HERC5 HSC70 HSP72 HSP73 HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 HSX70 IFI4 IKBKB IKBKG IKKA IKKB ILF2 ILF3 IPS1 ISG15 KIAA1271 KIAA1596 LKP MAP2K6 MAVS MEK6 MHF1 MHF2 MKK6 MOP6 MPHOSPH4 N NACP NCK NCK1 NDH2 NEMO NF45 NF90 NPM NPM1 NS P34CDC2 P53 P58IPK PACT PARK1 PHF9 PKR PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PRKMK6 PRKR PRKRA PRKRI PTPN2 PTPT RAX RNF147 SK1 SKK3 SMT3C SMT3H3 SNCA SPHK SPHK1 SPK STAT1 STAT3 STRA13 SUMO1 TARBP2 TCF16 TP53 TRBP TRIM25 TRS1 UBC9 UBCE9 UBCH7BP UBCH8 UBE2I UBE2L6 UBL1 UCRP VISA XRCC9 ZNF147 tat
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	ATP-dependent DNA/RNA helicase DHX36 ATP-dependent RNA helicase A Interferon regulatory factor 7 Myeloid differentiation primary response protein MyD88 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P19838 Q00653 Q04206 Q08211 Q92985 Q99836 Q9H2U1	DDX36 DDX9 DHX36 DHX9 IRF7 KIAA1488 LKP LYT10 MLEL1 MYD88 NDH2 NFKB1 NFKB2 NFKB3 RELA RHAU
Telomere Extension By Telomerase	ATP-dependent DNA helicase PIF1 Adrenocortical dysplasia protein homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 H/ACA ribonucleoprotein complex subunit 1 H/ACA ribonucleoprotein complex subunit 2 H/ACA ribonucleoprotein complex subunit 3 H/ACA ribonucleoprotein complex subunit DKC1 Protection of telomeres protein 1 Protein SHQ1 homolog Regulator of telomere elongation helicase 1 RuvB-like 1 RuvB-like 2 Serine/threonine-protein phosphatase 6 catalytic subunit Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A Serine/threonine-protein phosphatase 6 regulatory subunit 3 TERF1-interacting nuclear factor 2 Telomerase Cajal body protein 1 Telomerase reverse transcriptase Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O00743 O14746 O15084 O60832 P20248 P24941 P54274 P78396 Q15554 Q5H9R7 Q6PI26 Q96AP0 Q9BSI4 Q9BUR4 Q9H611 Q9NPE3 Q9NUX5 Q9NX24 Q9NY12 Q9NYB0 Q9NZ71 Q9Y230 Q9Y265	ACD ANKRD28 C11orf23 C15orf20 C20orf41 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 DKC1 DRIP5 EST2 GAR1 INO80H INO80J KIAA0379 KIAA1088 KIAA1558 NHL NHP2 NMP238 NOLA1 NOLA2 NOLA3 NOLA4 NOP10 PIF1 PIN2 PIP1 POT1 PP6R3 PPP6 PPP6C PPP6R3 PTOP RAP1 RTEL1 RUVBL1 RUVBL2 SAPL SAPS3 SHQ1 TCAB1 TCS1 TERF1 TERF2 TERF2IP TERT TIN2 TINF2 TINT1 TIP48 TIP49 TIP49A TIP49B TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TRT WDR79 WRAP53
Defective ABCG8 causes GBD4 and sitosterolemia	ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8	Q9H221 Q9H222	ABCG5 ABCG8
Defective ABCG5 causes sitosterolemia	ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8	Q9H221 Q9H222	ABCG5 ABCG8

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