TGF-beta receptor signaling activates SMADs
|
|
|
- ALK5
- C14orf141
- CBL
- CBL2
- DPC4
- FKBP1
- FKBP12
- FKBP1A
- FNRB
- FUR
- FURIN
- GP3A
- ITGA8
- ITGAV
- ITGB1
- ITGB3
- ITGB5
- ITGB6
- ITGB8
- LTBP1
- LTBP2
- LTBP3
- LTBP4
- MADH2
- MADH3
- MADH4
- MADR2
- MDF2
- MSK12
- MSK8
- NEDD8
- PACE
- PCSK3
- RNF55
- SKR4
- SMAD2
- SMAD3
- SMAD4
- TGFB
- TGFB1
- TGFB2
- TGFB3
- TGFBR1
- TGFBR2
- TGFBR3
- UBC12
- UBE2M
- VNRA
- VTNR
|
Homo sapiens (human)
|
|
TGFBR1 LBD Mutants in Cancer
|
|
|
- ALK5
- FKBP1
- FKBP12
- FKBP1A
- SKR4
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
|
Homo sapiens (human)
|
|
SMAD2/3 Phosphorylation Motif Mutants in Cancer
|
|
|
- ALK5
- MADH2
- MADH3
- MADR2
- SKR4
- SMAD2
- SMAD3
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
|
Homo sapiens (human)
|
|
TGFBR1 KD Mutants in Cancer
|
|
|
- ALK5
- MADH2
- MADH3
- MADR2
- SKR4
- SMAD2
- SMAD3
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
|
Homo sapiens (human)
|
|
TGFBR2 Kinase Domain Mutants in Cancer
|
|
|
- ALK5
- SKR4
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
|
Homo sapiens (human)
|
|
Transcriptional regulation of granulopoiesis
|
|
|
- ALL1
- AML1
- APRF
- BHLHA17
- BHLHE39
- BTEB2
- CAP20
- CBFA2
- CBFB
- CDK2
- CDK4
- CDKN1
- CDKN1A
- CDKN2
- CEBP
- CEBPA
- CEBPB
- CEBPE
- CIP1
- CKLF
- CSF3R
- CXXC7
- DEK
- DP1
- DP2
- E2F1
- EP300
- FLI1
- GATA2
- GCSFR
- GFI1
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST4H4
- HRX
- HTRX
- IKLF
- IL6R
- KLF5
- KMT2A
- LEF1
- MDA6
- MLL
- MLL1
- MYB
- MYC
- NR1B1
- NR2B1
- P300
- PIC1
- RARA
- RBBP3
- RUNX1
- RXRA
- SCL
- SDI1
- SPI1
- STAT3
- TAL1
- TCF5
- TCL5
- TFDP1
- TFDP2
- TRX1
- TSH2B
- WAF1
- ZNF163
|
Homo sapiens (human)
|
|
Suppression of apoptosis
|
|
|
- ALO17
- C17orf27
- CTSG
- ERK1
- ERK2
- GSK3A
- KIAA1554
- KIAA1618
- MAPK1
- MAPK3
- MYSTR
- PRKM1
- PRKM2
- PRKM3
- PSF
- RFP
- RNF213
- RNF76
- Rv3364c
- Rv3654c
- Rv3655c
- SFPQ
- TRIM27
- lprM
- mce3E
- mptpA
- ptpA
|
Homo sapiens (human)
|
|
Synthesis of 15-eicosatetraenoic acid derivatives
|
|
|
- ALOX15
- ALOX15B
- COX2
- GPX1
- GPX2
- GPX4
- LOG15
- PTGS2
|
Homo sapiens (human)
|
|
Biosynthesis of E-series 18(S)-resolvins
|
|
|
- ALOX15
- ALOX5
- HPGD
- LOG15
- LOG5
- LTA4
- LTA4H
- PGDH1
- SDR36C1
|
Homo sapiens (human)
|
|
Biosynthesis of E-series 18(R)-resolvins
|
|
|
- ALOX15
- ALOX5
- LOG15
- LOG5
- LTA4
- LTA4H
|
Homo sapiens (human)
|
|
Biosynthesis of protectins
|
|
|
- ALOX15
- CYP1A1
- CYP1A2
- LOG15
- LTA4
- LTA4H
|
Homo sapiens (human)
|
|
Synthesis of 5-eicosatetraenoic acids
|
|
|
- ALOX5
- ALOX5AP
- FLAP
- GPX1
- GPX2
- GPX4
- LOG5
- LTC4S
- PON
- PON1
- PON2
- PON3
|
Homo sapiens (human)
|
|
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives
|
|
|
|
Homo sapiens (human)
|
|
Biosynthesis of maresins
|
|
|
|
Homo sapiens (human)
|
|
Interleukin-18 signaling
|
|
|
- ALOX5
- FIL1Z
- IGIF
- IL13
- IL18
- IL18BP
- IL18R1
- IL18RAP
- IL1F4
- IL1F7
- IL1H4
- IL1R7
- IL1RP1
- IL1RRP
- IL37
- IL4
- LOG5
- NC30
|
Homo sapiens (human)
|
|
Biosynthesis of D-series resolvins
|
|
|
- ALOX5
- HPGD
- LOG5
- LTA4
- LTA4H
- PGDH1
- SDR36C1
|
Homo sapiens (human)
|
|
Biosynthesis of aspirin-triggered D-series resolvins
|
|
|
|
Homo sapiens (human)
|
|
Phenylalanine metabolism
|
|
|
- ALP
- ASRGL1
- CCBL1
- CRASH
- DCOH
- DHPR
- FIG1
- IL4I1
- KYAT1
- PAH
- PCBD
- PCBD1
- QDPR
- SDR33C1
|
Homo sapiens (human)
|
|
rRNA modification in the nucleus and cytosol
|
|
|
- ALP
- BAP28
- BING4
- BMS1
- BMS1L
- BUD23
- BXDC4
- C14orf111
- C15orf12
- C16orf42
- C17orf40
- C1orf107
- C2F
- C4orf9
- C6orf11
- C6orf153
- CIRH1A
- CRLZ1
- DCAF13
- DDX37
- DDX47
- DDX49
- DDX52
- DEF
- DHX37
- DIEXF
- DIMT1
- DIMT1L
- DKC1
- DRIM
- EMG1
- FBL
- FCF1
- FIB1
- FLRN
- GAR1
- HCA66
- HEATR1
- HRB2
- IMP3
- IMP4
- KIAA0007
- KIAA0185
- KIAA0187
- KIAA0266
- KIAA1517
- KIAA1709
- KIAA1988
- KRR1
- MERM1
- MHAT
- MPHOSPH10
- MPP10
- MRPS4
- NAT10
- NHP2
- NHP2L1
- NOC4L
- NOL1
- NOL11
- NOL14
- NOL5
- NOL5A
- NOL6
- NOLA1
- NOLA2
- NOLA3
- NOLA4
- NOP10
- NOP14
- NOP2
- NOP5
- NOP56
- NOP58
- NSUN1
- PDCD11
- PNO1
- PWP2
- PWP2H
- RCL1
- RNAC
- RNU3IP2
- ROK1
- RPC2
- RPCL1
- RPS14
- RPS2
- RPS4
- RPS6
- RPS7
- RPS9
- RRP36
- RRP7A
- RRP9
- RTC2
- SAS10
- SAZD
- SDCCAG16
- SNU13
- TBL3
- THUMPD1
- TRMT112
- TSR3
- U355K
- UND313L
- UTP10
- UTP11
- UTP11L
- UTP14A
- UTP14C
- UTP15
- UTP17
- UTP18
- UTP20
- UTP25
- UTP3
- UTP4
- UTP5
- UTP6
- WBSCR22
- WDR3
- WDR36
- WDR43
- WDR46
- WDR50
- WDR75
- WDSOF1
- cPERP-E
|
Homo sapiens (human)
|
|
PIWI-interacting RNA (piRNA) biogenesis
|
- ATP-dependent RNA helicase TDRD9
- Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
- DNA-directed RNA polymerase II subunit RPB11-a
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Heat shock protein HSP 90-alpha
- Inactive peptidyl-prolyl cis-trans isomerase FKBP6
- Mitochondrial cardiolipin hydrolase
- Myb-related protein A
- Piwi-like protein 1
- Piwi-like protein 2
- Piwi-like protein 4
- Probable ATP-dependent RNA helicase DDX4
- Protein maelstrom homolog
- Putative ATP-dependent RNA helicase TDRD12
- RNA helicase Mov10l1
- Small RNA 2'-O-methyltransferase
- Tudor and KH domain-containing protein
- Tudor domain-containing protein 1
- Tudor domain-containing protein 6
|
|
- ALP1
- AMYB
- ANKL1
- ASZ1
- C14orf75
- C1orf59
- C7orf7
- DDX4
- ECAT8
- FKBP36
- FKBP6
- GASZ
- HENMT1
- HILI
- HIWI
- HIWI2
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- MAEL
- MOV10L1
- MYBL1
- PIWI
- PIWIL1
- PIWIL2
- PIWIL4
- PLD6
- POLR2
- POLR2A
- POLR2B
- POLR2C
- POLR2D
- POLR2E
- POLR2F
- POLR2G
- POLR2H
- POLR2I
- POLR2J
- POLR2J1
- POLR2K
- POLR2L
- POLRF
- RPB7
- TDRD1
- TDRD12
- TDRD2
- TDRD6
- TDRD9
- TDRKH
- VASA
|
Homo sapiens (human)
|
|
Digestion
|
|
|
- ALPI
- GUC2C
- GUCA2
- GUCA2A
- GUCA2B
- GUCY2C
- PIR
- STAR
|
Homo sapiens (human)
|
|
ALPK1 signaling pathway
|
|
|
- ALPK1
- KIAA0733
- KIAA1527
- LAK
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- RNF85
- RPS27A
- T2BP
- TAB1
- TAB2
- TAB3
- TAK1
- TIFA
- TRAF6
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
Homo sapiens (human)
|
|
Intra-Golgi traffic
|
|
|
- ALPP
- ARF1
- ARNO
- ARNO3
- BET1L
- CEV14
- CIP150
- COG1
- COG2
- COG3
- COG4
- COG5
- COG6
- COG7
- COG8
- CUTL1
- CUX1
- CYT4
- CYTH1
- CYTH2
- CYTH3
- CYTH4
- D17S811E
- GIMPC
- GOLGA5
- GOLIM4
- GOLPH4
- GOLTC1
- GOSR1
- GOSR2
- GPP130
- GRP1
- GS15
- GS27
- GS28
- GTC90
- KIAA0258
- KIAA1134
- KIAA1381
- KIAA1432
- LDLB
- LDLC
- MAN1A1
- MAN1A2
- MAN1A3
- MAN1B
- MAN1C
- MAN1C1
- MAN2A1
- MAN2A2
- MANA2
- MANA2X
- NAPA
- NAPB
- NAPG
- NSF
- PLAP
- PSCD1
- PSCD2
- PSCD2L
- PSCD3
- PSCD4
- RAB30
- RAB33B
- RAB36
- RAB39
- RAB39A
- RAB41
- RETII
- RFG5
- RGP1
- RIC1
- SEC34
- SNAP29
- SNAPA
- SNAPB
- SNAPG
- STX16
- STX5
- STX5A
- STX6
- TRIP11
- VPS45
- VPS45A
- VPS45B
- VTI1A
- YKT6
|
Homo sapiens (human)
|
|
Formation of the beta-catenin:TCF transactivating complex
|
|
|
- ALR
- ASH2L
- ASH2L1
- BAF190A
- BCL9
- BCL9L
- BRG1
- C1orf28
- CBP
- CDC73
- CREBBP
- CTNNB
- CTNNB1
- DLNB11
- EP300
- EST2
- GRG4
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3-4
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H3FT
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HDAC1
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST3H3
- HIST4H4
- HRPT2
- HTATIP
- INO80H
- KAT5
- KIAA1261
- KIAA1547
- KMT2D
- LEF1
- LEO1
- MEN1
- MLL2
- MLL4
- NMP238
- P300
- PAF400
- PYGO1
- PYGO2
- RBBP5
- RBQ3
- RDL
- RPD3L1
- RUVBL1
- SCG2
- SMARCA4
- SNF2B
- SNF2L4
- TCF1
- TCF3
- TCF4
- TCF7
- TCF7L1
- TCF7L2
- TCS1
- TERT
- TIP49
- TIP49A
- TIP60
- TLE1
- TLE2
- TLE3
- TLE4
- TRRAP
- TRT
- TSH2B
|
Homo sapiens (human)
|
|
Energy dependent regulation of mTOR by LKB1-AMPK
|
|
|
- ALS2CR2
- AMPK
- AMPK1
- AMPK2
- AMPKG3
- C11orf59
- C7orf59
- CAB39
- CAB39L
- FRAP
- FRAP1
- FRAP2
- GBL
- HBXIP
- ILPIP
- KIAA0243
- KIAA1303
- LAMTOR1
- LAMTOR2
- LAMTOR3
- LAMTOR4
- LAMTOR5
- LKB1
- LST8
- LYK5
- MAP2K1IP1
- MAPBPIP
- MAPKSP1
- MLST8
- MO25
- MTOR
- PDRO
- PJS
- PPM1A
- PPPM1A
- PRKAA1
- PRKAA2
- PRKAB1
- PRKAB2
- PRKAG1
- PRKAG2
- PRKAG3
- RAFT1
- RAPT1
- RAPTOR
- RHEB
- RHEB2
- ROBLD3
- RPTOR
- RRAGA
- RRAGB
- RRAGC
- RRAGD
- SLC38A9
- STK11
- STRAD
- STRADA
- STRADB
- TSC
- TSC1
- TSC2
- TSC4
- URLC11
- XIP
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Homo sapiens (human)
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