GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1251 - 1275** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
Defective ACTH causes obesity and POMCD	Adrenocorticotropic hormone receptor Pro-opiomelanocortin	P01189 Q01718	ACTHR MC2R POMC	Homo sapiens (human)
Imatinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Activation of PUMA and translocation to mitochondria	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Bcl-2-binding component 3, isoforms 1/2 Cellular tumor antigen p53 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Tumor protein 63 Tumor protein p73	O15350 P04637 Q01094 Q13625 Q14186 Q14188 Q96KQ4 Q9BXH1 Q9H3D4	ASPP1 ASPP2 BBC3 BBP DP1 DP2 E2F1 KET KIAA0771 P53 P63 P73 P73H P73L PPP1R13B PUMA RBBP3 TFDP1 TFDP2 TP53 TP53BP2 TP63 TP73 TP73L	Homo sapiens (human)
HDR through Single Strand Annealing (SSA)	ATR-interacting protein BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA excision repair protein ERCC-1 DNA repair endonuclease XPF DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD52 homolog DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Tyrosine-protein kinase ABL1	O60671 O60921 O60934 O75943 P00519 P07992 P15927 P27694 P35244 P35249 P35250 P38398 P40937 P40938 P43351 P49959 P51530 P54132 Q06609 Q13315 Q13472 Q13535 Q14191 Q6WBX8 Q8WXE1 Q92547 Q92878 Q92889 Q92993 Q96E14 Q99638 Q99708 Q99728 Q9BSD3 Q9BX63 Q9H9A7 Q9UQ84	ABL ABL1 AGS1 ATM ATR ATRIP BACH1 BARD1 BLM BRCA1 BRIP1 C12orf32 C16orf75 C9orf76 CTIP DNA2 DNA2L ERCC1 ERCC11 ERCC4 EXO1 EXOI FANCJ FRP1 HEX1 HNGS1 HTATIP HUS1 JTK7 KAT5 KIAA0083 KIAA0259 MRE11 MRE11A NBN NBS NBS1 P95 R24L RAD1 RAD17 RAD50 RAD51 RAD51A RAD52 RAD9A RAD9B RBBP8 REC1 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 TIP60 TOP3 TOP3A TOPBP1 WRN XPF	Homo sapiens (human)
Synthesis of PIPs at the early endosome membrane	1-phosphatidylinositol 3-phosphate 5-kinase Inositol polyphosphate 4-phosphatase type II Inositol polyphosphate-4-phosphatase type I A Myotubularin-related protein 10 Myotubularin-related protein 12 Myotubularin Phosphatidylinositide phosphatase SAC2 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2 Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4 Phosphoinositide 3-kinase regulatory subunit 4 Polyphosphoinositide phosphatase Protein VAC14 homolog	O00443 O15327 Q08AM6 Q13496 Q13614 Q8NEB9 Q8TCG2 Q92562 Q96PE3 Q99570 Q9BTU6 Q9C0I1 Q9NXD2 Q9NYA4 Q9Y2H2 Q9Y2I7	CG2 FIG4 INPP4A INPP4B INPP5F KIAA0274 KIAA0647 KIAA0966 KIAA0981 KIAA1073 KIAA1682 MTM1 MTMR10 MTMR12 MTMR2 MTMR4 PI4K2A PI4K2B PIK3C2A PIK3C3 PIK3R4 PIKFYVE PIP3AP PIP5K3 SAC2 SAC3 TAX1BP2 TRX VAC14 VPS15 VPS34 ZFYVE11	Homo sapiens (human)
TRAF6 mediated IRF7 activation	Antiviral innate immune response receptor RIG-I CREB-binding protein E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Histone acetyltransferase p300 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon beta Interferon regulatory factor 3 Interferon regulatory factor 7 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Serine/threonine-protein kinase TBK1 Suppressor of IKBKE 1 TNF receptor-associated factor 2 TNF receptor-associated factor 6 TRAF family member-associated NF-kappa-B activator	O95786 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P32881 Q09472 Q12933 Q14164 Q14258 Q14653 Q7Z434 Q8IUD6 Q92793 Q92844 Q92985 Q9BRV8 Q9BYX4 Q9C037 Q9UHD2 Q9Y4K3	CBP CREBBP DDX58 EFP EP300 IFB IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB IFNB1 IKBKE IKKE IKKI IPS1 IRF3 IRF7 ITRAF KIAA0151 KIAA1271 MAVS MDA5 NAK P300 RH116 RIGI RNF135 RNF147 RNF85 RNF87 SIKE SIKE1 TANK TBK1 TRAF2 TRAF6 TRAP3 TRIM25 TRIM4 VISA ZNF147	Homo sapiens (human)
Prefoldin mediated transfer of substrate to CCT/TriC	Actin, cytoplasmic 1 Prefoldin subunit 1 Prefoldin subunit 2 Prefoldin subunit 3 Prefoldin subunit 4 Prefoldin subunit 5 Prefoldin subunit 6 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta-2 T-complex protein 1 subunit zeta Tubulin alpha-1A chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-4A chain Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain	O15212 O60925 P04350 P0DPH7 P0DPH8 P17987 P40227 P48643 P49368 P50990 P50991 P60709 P61758 P68366 P68371 P78371 Q13509 Q13885 Q71U36 Q92526 Q99471 Q99832 Q9BQE3 Q9BUF5 Q9BVA1 Q9H4B7 Q9NQP4 Q9UHV9	99D8.1 ACTB C21orf112 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT6A CCT6B CCT7 CCT8 CCTA CCTB CCTD CCTE CCTG CCTH CCTQ CCTZ HKE2 KIAA0002 KIAA0098 MM1 NIP7-1 PFD1 PFD2 PFD4 PFD5 PFD6 PFDN1 PFDN2 PFDN3 PFDN4 PFDN5 PFDN6 SRB TCP1 TRIC5 TUBA1 TUBA1A TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA4A TUBA6 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6 VBP1	Homo sapiens (human)
CREB phosphorylation	Cyclic AMP-dependent transcription factor ATF-1 MAP kinase-activated protein kinase 2 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-5	O75582 P18846 P49137 P51812 Q15349 Q15418	ATF1 ISPK1 MAPKAPK1A MAPKAPK1B MAPKAPK1C MAPKAPK2 MSK1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA5 RSK1 RSK2 RSK3	Homo sapiens (human)
Creatine metabolism	Creatine kinase B-type Creatine kinase M-type Creatine kinase S-type, mitochondrial Creatine kinase U-type, mitochondrial Glycine amidinotransferase, mitochondrial Guanidinoacetate N-methyltransferase Sodium- and chloride-dependent GABA transporter 3 Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent creatine transporter 1 Sodium-dependent proline transporter	P06732 P12277 P12532 P17540 P48029 P48065 P48066 P50440 Q14353 Q99884	AGAT BGT1 CKB CKBB CKM CKMM CKMT CKMT1A CKMT1B CKMT2 GABT3 GAMT GAT3 GATM PROT SLC6A11 SLC6A12 SLC6A7 SLC6A8	Homo sapiens (human)
Mitochondrial transcription initiation	DNA-directed RNA polymerase, mitochondrial Dimethyladenosine transferase 2, mitochondrial Transcription factor A, mitochondrial	O00411 Q00059 Q9H5Q4	NS5ATP5 POLRMT TCF6 TCF6L2 TFAM TFB2M	Homo sapiens (human)
Glycogen synthesis	1,4-alpha-glucan-branching enzyme E3 ubiquitin-protein ligase NHLRC1 Glycogen [starch] synthase, liver Glycogen [starch] synthase, muscle Glycogenin-1 Glycogenin-2 Laforin Phosphoglucomutase-1 Polyubiquitin-B Polyubiquitin-C Protein phosphatase 1 regulatory subunit 3C UTP--glucose-1-phosphate uridylyltransferase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15488 O95278 P0CG47 P0CG48 P13807 P36871 P46976 P54840 P62979 P62987 Q04446 Q16851 Q6VVB1 Q9UQK1	EPM2A EPM2B GBE1 GYG GYG1 GYG2 GYS GYS1 GYS2 NHLRC1 PGM1 PPP1R3C PPP1R5 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UGP1 UGP2	Homo sapiens (human)
Defective MPDU1 causes CDG-1f	Mannose-P-dolichol utilization defect 1 protein	O75352	MPDU1	Homo sapiens (human)	G59406KS
AMPK inhibits chREBP transcriptional activation activity	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-2 Adiponectin receptor protein 1 Adiponectin receptor protein 2 Adiponectin Carbohydrate-responsive element-binding protein Serine/threonine-protein kinase STK11	O43741 P54646 Q15831 Q15848 Q86V24 Q96A54 Q9NP71 Q9UGJ0	ACDC ACRP30 ADIPOQ ADIPOR1 ADIPOR2 AMPK AMPK2 APM1 BHLHD14 GBP28 LKB1 MIO MLXIPL PAQR1 PAQR2 PJS PRKAA2 PRKAB2 PRKAG2 STK11 TESBP1A WBSCR14	Homo sapiens (human)
DNA replication initiation	DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA primase large subunit DNA primase small subunit	P09884 P49642 P49643 P56282 Q07864 Q14181 Q9NR33 Q9NRF9	CHRAC17 DPE2 POLA POLA1 POLA2 POLE POLE1 POLE2 POLE3 POLE4 PRIM1 PRIM2 PRIM2A	Homo sapiens (human)
Digestion	Guanylate cyclase activator 2B Guanylin Guanylyl cyclase C Intestinal-type alkaline phosphatase Pirin	O00625 P09923 P25092 Q02747 Q16661	ALPI GUC2C GUCA2 GUCA2A GUCA2B GUCY2C PIR STAR	Homo sapiens (human)
Tat-mediated elongation of the HIV-1 transcript	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-T1 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Protein Tat RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 O60563 P04608 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P50613 P50750 P51946 P51948 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q08945 Q13888 Q13889 Q14241 Q15369 Q15370 Q6ZYL4 Q8IXH7 Q8IYF1 Q8WX92 Q92759 Q9H3P2 Q9Y5B0 Q9Y5B9	BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CCNH CCNT1 CDC2L4 CDK7 CDK9 CDKN7 COBRA1 CTDP1 ELL ELOA ELOA2 ELOB ELOC ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S KIAA1182 MAT1 MNAT1 MO15 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC tat	Homo sapiens (human)
Transcriptional Regulation by E2F6	Apoptotic protease-activating factor 1 Breast cancer type 1 susceptibility protein Cell division cycle 7-related protein kinase Chromobox protein homolog 3 Chromobox protein homolog 5 DNA endonuclease RBBP8 DNA repair protein RAD51 homolog 1 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Enhancer of polycomb homolog 1 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Histone-lysine N-methyltransferase EZH2 Lethal(3)malignant brain tumor-like protein 2 MAX gene-associated protein Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polycomb group RING finger protein 6 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 3 Protein UXT Protein max RING1 and YY1-binding protein Ribonucleoside-diphosphate reductase subunit M2 Serine/threonine-protein kinase Chk1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F6 YY1-associated factor 2	O00311 O14727 O14757 O75461 O75530 P31350 P35226 P35227 P38398 P45973 P61244 P78364 Q01094 Q06587 Q06609 Q09028 Q13185 Q14186 Q14188 Q15022 Q15910 Q16576 Q8IWI9 Q8IY57 Q8N488 Q8NDX5 Q969R5 Q96KQ7 Q99496 Q99708 Q9BYE7 Q9H2F5 Q9H9B1 Q9UBK9	APAF1 BAP1 BAT8 BHLHD4 BMI1 BRCA1 C6orf30 CBX3 CBX5 CDC7 CDC7L1 CHEK1 CHET9 CHK1 CTIP DEDAF DING DP1 DP2 E2F1 E2F6 EDR1 EDR3 EED EHMT1 EHMT2 EPC1 EUHMTASE1 EZH2 G9A GLP HIPI3 HP1A JJAZ1 KIAA0160 KIAA0413 KIAA0518 KIAA1876 KMT1C KMT1D KMT6 L3MBTL2 MAD5 MAX MBLR MEL18 MGA NG36 PCGF2 PCGF4 PCGF6 PH1 PH3 PHC1 PHC3 RAD51 RAD51A RBAP46 RBAP48 RBBP3 RBBP4 RBBP7 RBBP8 RECA RING1 RING1A RING1B RNF1 RNF110 RNF134 RNF2 RNF51 RNF53 RR2 RRM2 RYBP SUZ12 TFDP1 TFDP2 UXT YAF2 YEAF1 ZNF144	Homo sapiens (human)
E2F-enabled inhibition of pre-replication complex formation	Cyclin-dependent kinase 1 DNA helicase MCM8 G2/mitotic-specific cyclin-B1 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6	O43913 O43929 P06493 P14635 Q13415 Q13416 Q9UBD5 Q9UJA3 Q9Y5N6	C20orf154 CCNB CCNB1 CDC2 CDC28A CDK1 CDKN1 LATHEO MCM8 ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L P34CDC2 PARC1	Homo sapiens (human)
CTLA4 inhibitory signaling	Cytotoxic T-lymphocyte protein 4 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11	P06239 P06241 P07947 P07948 P16410 P30153 P30154 P31749 P31751 P33681 P42081 P62714 P67775 Q06124 Q13362 Q14738 Q15172 Q15173 Q16537 Q9Y243	AKT1 AKT2 AKT3 CD152 CD28LG CD28LG1 CD28LG2 CD80 CD86 CTLA4 FYN JTK8 KIAA0044 LAB7 LCK LYN PKB PKBG PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PTP2C PTPN11 RAC SHPTP2 YES YES1	Homo sapiens (human)
Assembly and release of respiratory syncytial virus (RSV) virions	Fusion glycoprotein F0 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Matrix protein Nucleoprotein Phosphoprotein Protein M2-1 RNA-directed RNA polymerase L	P03418 P03420 P03421 P04545 P07900 P08238 P0DOE7 P28887	F HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB L M M2-1 N P	Homo sapiens (human)
G-protein activation	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Mu-type opioid receptor Pro-opiomelanocortin Proenkephalin-B	O14610 O14775 O60262 O95837 P01189 P01213 P16520 P29992 P30679 P35372 P50148 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 MOR1 OPRM1 PDYN POMC	Homo sapiens (human)
Energy dependent regulation of mTOR by LKB1-AMPK	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Calcium-binding protein 39-like Calcium-binding protein 39 GTP-binding protein Rheb Hamartin Neutral amino acid transporter 9 Protein phosphatase 1A Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR STE20-related kinase adapter protein alpha STE20-related kinase adapter protein beta Serine/threonine-protein kinase STK11 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Tuberin	O43504 O43741 P35813 P42345 P49815 P54619 P54646 Q0VGL1 Q13131 Q15382 Q15831 Q5VZM2 Q6IAA8 Q7L523 Q7RTN6 Q8N122 Q8NBW4 Q92574 Q9BVC4 Q9C0K7 Q9H9S4 Q9HB90 Q9NQL2 Q9UGI9 Q9UGJ0 Q9UHA4 Q9Y2Q5 Q9Y376 Q9Y478	ALS2CR2 AMPK AMPK1 AMPK2 AMPKG3 C11orf59 C7orf59 CAB39 CAB39L FRAP FRAP1 FRAP2 GBL HBXIP ILPIP KIAA0243 KIAA1303 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LKB1 LST8 LYK5 MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MO25 MTOR PDRO PJS PPM1A PPPM1A PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 STK11 STRAD STRADA STRADB TSC TSC1 TSC2 TSC4 URLC11 XIP	Homo sapiens (human)
RHOBTB1 GTPase cycle	COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 4 Cleavage and polyadenylation specificity factor subunit 7 Cullin-3 Drebrin E3 ubiquitin-protein ligase BRE1A E3 ubiquitin-protein ligase RBBP6 Heterogeneous nuclear ribonucleoproteins C1/C2 Msx2-interacting protein RNA-binding motif protein, X chromosome Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related BTB domain-containing protein 1 Serine/arginine repetitive matrix protein 1 Serine/threonine-protein kinase 38 T-complex protein 1 subunit beta T-complex protein 1 subunit eta Thioredoxin-like protein 1 Transformer-2 protein homolog beta Unconventional myosin-VI Vimentin cGMP-specific 3',5'-cyclic phosphodiesterase	O43396 O75116 O76074 O94844 P07910 P08670 P38159 P61201 P62995 P78371 Q13098 Q13464 Q13618 Q15208 Q16643 Q5VTR2 Q7Z6E9 Q8IYB3 Q8N684 Q96T58 Q99832 Q9BT78 Q9UM54	99D8.1 BRE1A CCT2 CCT7 CCTB CCTH COPS1 COPS2 COPS4 CPSF7 CSN1 CSN2 CSN4 CUL3 D0S117E DBN1 GPS1 HNRNPC HNRPC HNRPG KIAA0389 KIAA0617 KIAA0619 KIAA0740 KIAA0929 MINT MYO6 NDR1 NIP7-1 P2PR PACT PDE5 PDE5A RBBP6 RBMX RBMXP1 RBQ1 RHOBTB1 RNF20 ROCK1 ROCK2 SFRS10 SHARP SPEN SRM160 SRRM1 STK38 TRA2B TRIP15 TRP32 TXL TXNL TXNL1 VIM	Homo sapiens (human)
Defective SLC26A2 causes chondrodysplasias	Sulfate transporter	P50443	DTD DTDST SLC26A2	Homo sapiens (human)
Defective ALG14 causes ALG14-CMS	UDP-N-acetylglucosamine transferase subunit ALG13 UDP-N-acetylglucosamine transferase subunit ALG14	Q96F25 Q9NP73	ALG13 ALG14 CXorf45 GLT28D1	Homo sapiens (human)

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