GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1351 - 1375** of **2074** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism
RUNX3 regulates CDKN1A transcription	Cellular tumor antigen p53 Cyclin-dependent kinase inhibitor 1 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein Zinc finger homeobox protein 3	P01137 P04637 P38936 P84022 Q13485 Q13761 Q15911	AML2 ATBF1 C16orf47 CAP20 CBFA3 CDKN1 CDKN1A CIP1 DPC4 MADH3 MADH4 MDA6 P53 PEBP2A3 PIC1 RUNX3 SDI1 SMAD3 SMAD4 TGFB TGFB1 TP53 WAF1 ZFHX3	Homo sapiens (human)
TGF-beta receptor signaling activates SMADs	E3 ubiquitin-protein ligase CBL Furin Integrin alpha-8 Integrin alpha-V Integrin beta-1 Integrin beta-3 Integrin beta-5 Integrin beta-6 Integrin beta-8 Latent-transforming growth factor beta-binding protein 1 Latent-transforming growth factor beta-binding protein 2 Latent-transforming growth factor beta-binding protein 3 Latent-transforming growth factor beta-binding protein 4 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NEDD8-conjugating enzyme Ubc12 NEDD8 Peptidyl-prolyl cis-trans isomerase FKBP1A TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta receptor type 3 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein	P01137 P05106 P05556 P06756 P09958 P10600 P18084 P18564 P22681 P26012 P36897 P37173 P53708 P61081 P61812 P62942 P84022 Q03167 Q13485 Q14766 Q14767 Q15796 Q15843 Q8N2S1 Q9NS15	ALK5 C14orf141 CBL CBL2 DPC4 FKBP1 FKBP12 FKBP1A FNRB FUR FURIN GP3A ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP2 LTBP3 LTBP4 MADH2 MADH3 MADH4 MADR2 MDF2 MSK12 MSK8 NEDD8 PACE PCSK3 RNF55 SKR4 SMAD2 SMAD3 SMAD4 TGFB TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TGFBR3 UBC12 UBE2M VNRA VTNR	Homo sapiens (human)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase SMURF1 Junctional adhesion molecule A Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Peptidyl-prolyl cis-trans isomerase FKBP1A Polyubiquitin-B Polyubiquitin-C Protein kinase C zeta type Rho guanine nucleotide exchange factor 18 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P01137 P0CG47 P0CG48 P36897 P37173 P61586 P62942 P62979 P62987 Q05513 Q6ZSZ5 Q8TEW0 Q9HCE7 Q9NPB6 Q9P2M7 Q9Y624	ALK5 ARH12 ARHA ARHGEF18 CGN F11R FKBP1 FKBP12 FKBP1A JAM1 JCAM KIAA0521 KIAA1319 KIAA1625 PAR3 PAR3A PAR6A PARD3 PARD6A PKC2 PRKCZ RHO12 RHOA RPS27A SKR4 SMURF1 TGFB TGFB1 TGFBR1 TGFBR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
TGFBR1 LBD Mutants in Cancer	Peptidyl-prolyl cis-trans isomerase FKBP1A TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P62942	ALK5 FKBP1 FKBP12 FKBP1A SKR4 TGFB TGFB1 TGFBR1 TGFBR2	Homo sapiens (human)
SMAD2/3 Phosphorylation Motif Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P84022 Q15796	ALK5 MADH2 MADH3 MADR2 SKR4 SMAD2 SMAD3 TGFB TGFB1 TGFBR1 TGFBR2	Homo sapiens (human)
TGFBR1 KD Mutants in Cancer	Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173 P84022 Q15796	ALK5 MADH2 MADH3 MADR2 SKR4 SMAD2 SMAD3 TGFB TGFB1 TGFBR1 TGFBR2	Homo sapiens (human)
TGFBR2 Kinase Domain Mutants in Cancer	TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173	ALK5 SKR4 TGFB TGFB1 TGFBR1 TGFBR2	Homo sapiens (human)
TGFBR2 MSI Frameshift Mutants in Cancer	TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P37173	TGFB TGFB1 TGFBR2	Homo sapiens (human)
ARMS-mediated activation	14-3-3 protein beta/alpha Adapter molecule crk Beta-nerve growth factor High affinity nerve growth factor receptor Kinase D-interacting substrate of 220 kDa Ras-related protein Rap-1A Serine/threonine-protein kinase B-raf	P01138 P04629 P15056 P31946 P46108 P62834 Q9ULH0	ARMS BRAF BRAF1 CRK KIAA1250 KIDINS220 KREV1 MTC NGF NGFB NTRK1 RAFB1 RAP1A TRK TRKA YWHAB	Homo sapiens (human)
Signalling to p38 via RIT and RIN	Beta-nerve growth factor GTP-binding protein Rit1 GTP-binding protein Rit2 High affinity nerve growth factor receptor Serine/threonine-protein kinase B-raf	P01138 P04629 P15056 Q92963 Q99578	BRAF BRAF1 MTC NGF NGFB NTRK1 RAFB1 RIBB RIN RIT RIT1 RIT2 ROC1 ROC2 TRK TRKA	Homo sapiens (human)
PLC-gamma1 signalling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629 P19174	MTC NGF NGFB NTRK1 PLC1 PLCG1 TRK TRKA	Homo sapiens (human)
Signalling to STAT3	Beta-nerve growth factor High affinity nerve growth factor receptor Signal transducer and activator of transcription 3	P01138 P04629 P40763	APRF MTC NGF NGFB NTRK1 STAT3 TRK TRKA	Homo sapiens (human)
TRKA activation by NGF	Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629	MTC NGF NGFB NTRK1 TRK TRKA	Homo sapiens (human)
NRIF signals cell death from the nucleus	Beta-nerve growth factor Centromere protein R Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Mitogen-activated protein kinase 8 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Sequestosome-1 TNF receptor-associated factor 6 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P01138 P08138 P0CG47 P0CG48 P45983 P49768 P49810 P62979 P62987 Q13352 Q13501 Q8WW43 Q92542 Q96BI3 Q9NZ42 Q9Y4K3	AD3 AD4 APH1A APH1B CENPR ITGB3BP JNK1 KIAA0253 MAPK8 NCSTN NGF NGFB NGFR NRIF3 ORCA OSIL PEN2 PRKM8 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF85 RPS27A SAPK1 SAPK1C SQSTM1 STM2 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
NADE modulates death signalling	14-3-3 protein epsilon Beta-nerve growth factor Caspase-2 Caspase-3 Protein BEX3 Tumor necrosis factor receptor superfamily member 16	P01138 P08138 P42574 P42575 P62258 Q00994	BEX3 CASP2 CASP3 CPP32 DXS6984E ICH1 NADE NEDD2 NGF NGFB NGFR NGFRAP1 TNFRSF16 YWHAE	Homo sapiens (human)
Axonal growth stimulation	Beta-nerve growth factor Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P01138 P08138 P52565 P61586	ARH12 ARHA ARHGDIA GDIA1 NGF NGFB NGFR RHO12 RHOA TNFRSF16	Homo sapiens (human)
NFG and proNGF binds to p75NTR	Beta-nerve growth factor Sortilin-related VPS10 domain containing receptor 3 Tumor necrosis factor receptor superfamily member 16	P01138 P08138 Q17R88	NGF NGFB NGFR SORCS3 TNFRSF16	Homo sapiens (human)
NGF processing	Beta-nerve growth factor Furin Proprotein convertase subtilisin/kexin type 5 Proprotein convertase subtilisin/kexin type 6	P01138 P09958 P29122 Q92824	FUR FURIN NGF NGFB PACE PACE4 PC5 PC6 PCSK3 PCSK5 PCSK6	Homo sapiens (human)
Frs2-mediated activation	14-3-3 protein beta/alpha Beta-nerve growth factor Crk-like protein Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Rap guanine nucleotide exchange factor 1 Ras-related protein Rap-1A Serine/threonine-protein kinase B-raf	P01138 P15056 P27361 P28482 P31946 P36507 P46109 P62834 Q02750 Q13905 Q8WU20	BRAF BRAF1 CRKL ERK1 ERK2 FRS2 GRF2 KREV1 MAP2K1 MAP2K2 MAPK1 MAPK3 MEK1 MEK2 MKK2 NGF NGFB PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAFB1 RAP1A RAPGEF1 YWHAB	Homo sapiens (human)
Physiological factors	Atrial natriuretic peptide receptor 1 Atrial natriuretic peptide receptor 2 Atrial natriuretic peptide-converting enzyme C-type natriuretic peptide Histone acetyltransferase KAT2B Homeobox protein Nkx-2.5 Homeodomain-interacting protein kinase 1 Homeodomain-interacting protein kinase 2 Liver carboxylesterase 1 Natriuretic peptides A Neprilysin T-box transcription factor TBX5 Transcription factor GATA-4 WW domain-containing transcription regulator protein 1	P01160 P08473 P16066 P20594 P23141 P23582 P43694 P52952 Q86Z02 Q92831 Q99593 Q9GZV5 Q9H2X6 Q9Y5Q5	ANP ANPRA ANPRB CES1 CES2 CNP2 CORIN CRN CSX EPN GATA4 HIPK1 HIPK2 KAT2B KIAA0630 MME MYAK NBAK2 NKX2-5 NKX2.5 NKX2E NPPA NPPC NPR1 NPR2 PCAF PND SES1 TAZ TBX5 TMPRSS10 WWTR1	Homo sapiens (human)
YAP1- and WWTR1 (TAZ)-stimulated gene expression	CCN family member 2 Histone acetyltransferase KAT2B Homeobox protein Nkx-2.5 Homeodomain-interacting protein kinase 1 Homeodomain-interacting protein kinase 2 Natriuretic peptides A T-box transcription factor TBX5 Transcription factor GATA-4 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-4 Transcriptional enhancer factor TEF-5 WW domain-containing transcription regulator protein 1	P01160 P28347 P29279 P43694 P46937 P52952 Q15561 Q15562 Q86Z02 Q92831 Q99593 Q99594 Q9GZV5 Q9H2X6	ANP CCN2 CSX CTGF GATA4 HCS24 HIPK1 HIPK2 IGFBP8 KAT2B KIAA0630 MYAK NBAK2 NKX2-5 NKX2.5 NKX2E NPPA PCAF PND RTEF1 TAZ TBX5 TCF13 TCF13L1 TEAD1 TEAD2 TEAD3 TEAD4 TEAD5 TEF1 TEF3 TEF4 TEF5 WWTR1 YAP1 YAP65	Homo sapiens (human)
Vasopressin-like receptors	Oxytocin receptor Oxytocin-neurophysin 1 Vasopressin V1a receptor Vasopressin V1b receptor Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin	P01178 P01185 P30518 P30559 P37288 P47901	ADHR ARVP AVP AVPR1 AVPR1A AVPR1B AVPR2 AVPR3 DIR DIR3 OT OXT OXTR V2R VP VPR3	Homo sapiens (human)
Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)	Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin	P01185 P30518	ADHR ARVP AVP AVPR2 DIR DIR3 V2R VP	Homo sapiens (human)
Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)	Vasopressin V1a receptor Vasopressin V1b receptor Vasopressin-neurophysin 2-copeptin	P01185 P37288 P47901	ARVP AVP AVPR1 AVPR1A AVPR1B AVPR3 VP VPR3	Homo sapiens (human)
Opioid Signalling	Mu-type opioid receptor Pro-opiomelanocortin Proenkephalin-B	P01189 P01213 P35372	MOR1 OPRM1 PDYN POMC	Homo sapiens (human)

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