Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
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- A4
- AD1
- APP
- APT1LG1
- BCL2L11
- BIM
- CANPL1
- CANPL2
- CAPN1
- CAPN2
- CAPN4
- CAPNS
- CAPNS1
- CAPNS2
- CAST
- CD95L
- CDC25A
- CDC25B
- CDC25C
- CDC25HU2
- CDK5
- CDK5R
- CDK5R1
- CDKN5
- FASL
- FASLG
- FKHRL1
- FOXO3
- FOXO3A
- GOLGA2
- JUN
- LMN2
- LMNB
- LMNB1
- NCK5A
- NKEFB
- PAGA
- PAGB
- PRDX1
- PRDX2
- PSSALRE
- SOD2
- TDPX1
- TDPX2
- TNFSF6
- YWHAE
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Homo sapiens (human)
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RNA Polymerase III Transcription Initiation From Type 1 Promoter
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- DNA-directed RNA polymerase III subunit RPC10
- DNA-directed RNA polymerase III subunit RPC1
- DNA-directed RNA polymerase III subunit RPC2
- DNA-directed RNA polymerase III subunit RPC3
- DNA-directed RNA polymerase III subunit RPC4
- DNA-directed RNA polymerase III subunit RPC5
- DNA-directed RNA polymerase III subunit RPC6
- DNA-directed RNA polymerase III subunit RPC7-like
- DNA-directed RNA polymerase III subunit RPC7
- DNA-directed RNA polymerase III subunit RPC8
- DNA-directed RNA polymerase III subunit RPC9
- DNA-directed RNA polymerases I and III subunit RPAC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription factor 3C polypeptide 1
- General transcription factor 3C polypeptide 2
- General transcription factor 3C polypeptide 3
- General transcription factor 3C polypeptide 4
- General transcription factor 3C polypeptide 5
- General transcription factor 3C polypeptide 6
- Protein POLR1D, isoform 2
- TATA-box-binding protein
- Transcription factor IIIA
- Transcription factor IIIB 90 kDa subunit
- Transcription factor TFIIIB component B'' homolog
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- BDP1
- BN51
- BN51T
- BRF
- BRF1
- C6orf51
- CRCP
- GTF2D1
- GTF3A
- GTF3B
- GTF3C1
- GTF3C2
- GTF3C3
- GTF3C4
- GTF3C5
- GTF3C6
- KIAA0011
- KIAA1241
- KIAA1452
- KIAA1665
- KIAA1689
- POLR1C
- POLR1D
- POLR1E
- POLR2E
- POLR2F
- POLR2H
- POLR2K
- POLR2L
- POLR3A
- POLR3B
- POLR3C
- POLR3D
- POLR3E
- POLR3F
- POLR3G
- POLR3GL
- POLR3H
- POLR3K
- POLRF
- RPC11
- RPC8
- TAF3B2
- TAF3C
- TBP
- TF2D
- TFIID
- TFNR
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Homo sapiens (human)
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Translation of Structural Proteins
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Homo sapiens (human)
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Aspartate and asparagine metabolism
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|
|
- ACY2
- AGC1
- ARALAR1
- ASNS
- ASP
- ASPA
- ASPG
- C14orf76
- CML3
- FOLH
- FOLH1
- FOLH1B
- GADL1
- GOT1
- GOT2
- KYAT4
- NAALAD1
- NAALAD2
- NAT8L
- PSM
- PSMA
- PSMAL
- SLC25A12
- SLC25A13
- TS11
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Homo sapiens (human)
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pexidartinib-resistant FLT3 mutants
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Homo sapiens (human)
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EML4 and NUDC in mitotic spindle formation
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- AHCTF1
- AIK2
- AIM1
- AIRK2
- API4
- APITD1
- ARK2
- AURKB
- B9D2
- BIRC5
- BUB1
- BUB1B
- BUB1L
- BUB3
- BUBR1
- C16orf56
- C16orf60
- C18orf24
- C1orf155
- C1orf48
- C20orf172
- C22orf18
- C2orf2
- C6orf139
- CASC5
- CCDC99
- CDC20
- CDCA1
- CDCA8
- CENPA
- CENPC
- CENPC1
- CENPE
- CENPF
- CENPH
- CENPI
- CENPK
- CENPL
- CENPM
- CENPN
- CENPO
- CENPP
- CENPQ
- CENPR
- CENPS
- CENPT
- CENPU
- CKAP5
- CLASP1
- CLASP2
- CLIP1
- CRM1
- CYLN1
- D3S1231E
- DHC1
- DLC1
- DLC2
- DNCH1
- DNCI1
- DNCI2
- DNCIC1
- DNCIC2
- DNCL
- DNCL1
- DNCLC1
- DNCLI1
- DNCLI2
- DNECL
- DSN1
- DYHC
- DYNC1H1
- DYNC1I1
- DYNC1I2
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- ELYS
- EMAPL4
- EML4
- EOPA
- ERCC6L
- FAAP16
- FAM33A
- FSHPRH1
- HDLC1
- HEC
- HEC1
- IAP4
- ICEN19
- ICEN22
- ICEN24
- ICEN32
- ICEN33
- ICEN35
- ICEN36
- ICEN37
- ICEN39
- ICEN7
- INCENP
- ITGB3BP
- KIAA0044
- KIAA0097
- KIAA0166
- KIAA0197
- KIAA0325
- KIAA0622
- KIAA0627
- KIAA1361
- KIAA1470
- KIAA1570
- KIAA1835
- KIAA1995
- KIF18A
- KIF2
- KIF2A
- KIF2B
- KIF2C
- KLIP1
- KNL1
- KNS2
- KNSL6
- KNTC1
- KNTC2
- LIC2
- LIS1
- LRPR1
- MAD1
- MAD1L1
- MAD2
- MAD2L1
- MAD3L
- MAP3K16
- MAPRE1
- MARKK
- MAST1
- MCM21R
- MDCR
- MDS
- MHF1
- MIS12
- MIS13
- MITAP1
- MKSR2
- MLF1IP
- MPS1
- NDC80
- NDE1
- NDEL1
- NEK6
- NEK7
- NEK8
- NEK9
- NERCC
- NRIF3
- NSL1
- NUDC
- NUDE
- NUDEL
- NUF2
- NUF2R
- NUP107
- NUP120
- NUP133
- NUP160
- NUP358
- NUP37
- NUP43
- NUP75
- NUP85
- PAFAH1B1
- PAFAHA
- PANE1
- PBIP1
- PCNT1
- PESCRG3
- PICH
- PLK
- PLK1
- PMF1
- PPP1CC
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- RANBP2
- RANGAP1
- RCC2
- ROD
- RPS27
- RSN
- SD
- SEC13
- SEC13A
- SEC13L1
- SEC13R
- SGO1
- SGO2
- SGOL1
- SGOL2
- SKA1
- SKA2
- SPBC24
- SPBC25
- SPC24
- SPC25
- SPDL1
- SSK1
- STK1
- STK12
- STK5
- TAOK1
- TD60
- TMBS62
- TXBP181
- XPO1
- ZW10
- ZWILCH
- ZWINT
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Homo sapiens (human)
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SARS-CoV-1 modulates host translation machinery
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- 1a
- CCG2
- D6S218E
- EEF1A
- EEF1A1
- EF1A
- FAU
- FTE1
- HNRNPA1
- HNRPA1
- LAMBR
- LAMR1
- LENG7
- MFTL
- MPS1
- N
- RIG
- RPS10
- RPS11
- RPS12
- RPS13
- RPS14
- RPS15
- RPS15A
- RPS16
- RPS17
- RPS17L
- RPS18
- RPS19
- RPS2
- RPS20
- RPS21
- RPS23
- RPS24
- RPS25
- RPS26
- RPS27
- RPS27A
- RPS27L
- RPS28
- RPS29
- RPS3
- RPS3A
- RPS4
- RPS4X
- RPS4Y
- RPS4Y1
- RPS4Y2
- RPS4Y2P
- RPS5
- RPS6
- RPS7
- RPS8
- RPS9
- RPSA
- SCAR
- UBA80
- UBCEP1
- rep
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Homo sapiens (human)
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Regulation of lipid metabolism by PPARalpha
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- AIB3
- ARC205
- BAF60C
- BHLHE74
- BHLHE75
- CARM1
- CBP
- CHD9
- CREBBP
- CRSP1
- CRSP200
- CTG26
- DRIP205
- DRIP230
- FABP1
- FABPL
- HCA137
- HDAC3
- HELZ2
- IRA1
- KIAA0181
- KIAA0308
- KIAA1047
- KIAA1769
- KISH2
- MED1
- NCOA1
- NCOA2
- NCOA6
- NCOA6IP
- NCOR1
- NCOR2
- NR1C1
- NR2B1
- PBP
- PIMT
- PPAR
- PPARA
- PPARBP
- PPARGBP
- PRIC285
- PRIC320
- PRMT4
- RAP250
- RB18A
- RXRA
- SIN3A
- SMARCD3
- SRC1
- SRC2
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TGS1
- TIF2
- TRAP220
- TRBP
- TRIP2
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Homo sapiens (human)
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RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
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- CDK-activating kinase assembly factor MAT1
- Cyclin-H
- Cyclin-dependent kinase 7
- DNA-directed RNA polymerase II subunit RPB11-a
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB3
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB7
- DNA-directed RNA polymerase II subunit RPB9
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIF subunit 1
- General transcription factor IIF subunit 2
- General transcription factor IIH subunit 1
- General transcription factor IIH subunit 2
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 4
- General transcription factor IIH subunit 5
- Transcription elongation factor SPT5
- mRNA cap guanine-N7 methyltransferase
- mRNA-capping enzyme
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- BTF2
- BTF2P44
- C6orf175
- CAK
- CAK1
- CAP1A
- CAP35
- CCNH
- CDK7
- CDKN7
- ERCC2
- ERCC3
- GTF2F1
- GTF2F2
- GTF2H1
- GTF2H2
- GTF2H3
- GTF2H4
- GTF2H5
- KIAA0398
- MAT1
- MNAT1
- MO15
- POLR2
- POLR2A
- POLR2B
- POLR2C
- POLR2D
- POLR2E
- POLR2F
- POLR2G
- POLR2H
- POLR2I
- POLR2J
- POLR2J1
- POLR2K
- POLR2L
- POLRF
- RAP30
- RAP74
- RNF66
- RNGTT
- RNMT
- RPB7
- SPT5
- SPT5H
- STK1
- SUPT5H
- TTDA
- XPB
- XPBC
- XPD
- XPDC
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Homo sapiens (human)
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Adrenaline signalling through Alpha-2 adrenergic receptor
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- ADRA2A
- ADRA2B
- ADRA2C
- ADRA2L1
- ADRA2L2
- ADRA2R
- ADRA2RL1
- ADRA2RL2
- ADRAR
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Homo sapiens (human)
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crizotinib-resistant ALK mutants
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Homo sapiens (human)
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RUNX2 regulates bone development
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- BSP1
- CBFB
- DPC4
- MADH1
- MADH4
- MADH6
- MADR1
- RBM14
- SIP
- SMAD1
- SMAD4
- SMAD6
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Homo sapiens (human)
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Defective MTRR causes HMAE
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Homo sapiens (human)
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Vitamin C (ascorbate) metabolism
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|
- CYB5
- CYB5A
- CYB5R3
- DIA1
- GLUT1
- GLUT3
- GSTO1
- GSTO2
- GSTTLP28
- KIAA0238
- NBTL1
- SLC23A1
- SLC23A2
- SLC2A1
- SLC2A3
- SVCT1
- SVCT2
- YSPL2
- YSPL3
|
Homo sapiens (human)
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ATF4 activates genes in response to endoplasmic reticulum stress
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|
- ASNS
- ATF3
- ATF4
- ATF6
- CCL2
- CEBPB
- CEBPG
- CHOP
- CHOP10
- CML28
- CREB2
- CSL4
- CXCL8
- DAN
- DCP2
- DDIT3
- DIS3
- EXOSC1
- EXOSC2
- EXOSC3
- EXOSC4
- EXOSC5
- EXOSC6
- EXOSC7
- EXOSC8
- EXOSC9
- FUBP2
- GADD153
- HAP3
- HERP
- HERPUD1
- IBP1
- IGFBP1
- IL8
- KHSRP
- KIAA0025
- KIAA0116
- KIAA1008
- MCP1
- MIF1
- MTR3
- NFYA
- NFYB
- NFYC
- NUDT20
- OIP2
- PARN
- PMSCL1
- RRP4
- RRP40
- RRP41
- RRP42
- RRP43
- RRP44
- RRP46
- SCYA2
- SKI6
- TCF5
- TS11
- TXREB
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Homo sapiens (human)
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|
NOTCH3 Intracellular Domain Regulates Transcription
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- BHLHB31
- BHLHB32
- BHLHB33
- BHLHB38
- BHLHB39
- BLBP
- CBP
- CG1
- CHF1
- CHF2
- CREBBP
- CXorf6
- DLG7
- DLGAP5
- EP300
- FABP7
- FABPB
- GCN5
- GCN5L2
- GRL
- HERP
- HERP1
- HERP2
- HES1
- HES5
- HESR1
- HEY1
- HEY2
- HEYL
- HL
- HRT1
- HRT2
- HRT3
- HRY
- IGKJRB
- IGKJRB1
- KAT2A
- KAT2B
- KIAA0008
- KIAA0200
- KIAA0620
- KIAA0869
- KIAA1816
- KIAA1819
- KIBRA
- MAML1
- MAML2
- MAML3
- MAMLD1
- MRG
- NOTCH1
- NOTCH3
- P300
- PBX1
- PCAF
- PLXND1
- PRL
- PTCRA
- RBPJ
- RBPJK
- RBPSUH
- SKIIP
- SKIP
- SNW1
- STAT1
- TAN1
- WWC1
|
Homo sapiens (human)
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|
MPS IIIC - Sanfilippo syndrome C
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|
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|
Homo sapiens (human)
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|
Circadian Clock
|
|
|
- AIB3
- ARC205
- ARNTL
- ATF2
- BAF60C
- BHLHB3
- BHLHE41
- BHLHE5
- BHLHE74
- BHLHE75
- BHLHE78
- BHLHE8
- BHLHE9
- BMAL1
- BTRC
- BTRCP
- CARM1
- CBP
- CHD9
- CLOCK
- CREB2
- CREBBP
- CREBP1
- CRSP1
- CRSP200
- CRTC1
- CRTC2
- CRTC3
- CRY1
- CRY2
- CSNK1D
- CSNK1E
- CUL1
- DEC2
- DRIP205
- DRIP230
- E4BP4
- EAR1
- EMC19
- EP300
- FBL3A
- FBW1A
- FBXL3
- FBXL3A
- FBXW1A
- GRL
- HCA137
- HCKID
- HDAC3
- HELZ2
- HIF1A
- HREV
- IL3BP1
- IRA1
- KIAA0181
- KIAA0308
- KIAA0334
- KIAA0347
- KIAA0482
- KIAA0616
- KIAA0658
- KIAA1047
- KIAA1769
- KIAA1820
- KISH2
- LEM6
- MECT1
- MED1
- MEF2C
- MEF2D
- MOP1
- MOP3
- MOP4
- NCOA1
- NCOA2
- NCOA6
- NCOA6IP
- NCOR1
- NFIL3
- NPAS2
- NR1C1
- NR1D1
- NR1F1
- NR2B1
- NR3C1
- NRIP1
- OCP2
- P300
- PASD3
- PASD4
- PASD8
- PBP
- PER
- PER1
- PER2
- PGC1
- PGC1A
- PHLL1
- PIMT
- PPAR
- PPARA
- PPARBP
- PPARGBP
- PPARGC1
- PPARGC1A
- PPP1A
- PPP1CA
- PPP1CB
- PPP1CC
- PRIC285
- PRIC320
- PRMT4
- RAI1
- RAP250
- RB18A
- RBM4
- RBM4A
- RIGUI
- RORA
- RPS27A
- RXRA
- RZRA
- SHARP1
- SIK
- SIK1
- SIR2L1
- SIRT1
- SKP1
- SKP1A
- SMARCD3
- SNF1LK
- SRC1
- SRC2
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TCEB1L
- TGS1
- THRAL
- TIF2
- TORC1
- TORC2
- TORC3
- TRAP220
- TRBP
- TRIP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WAMTP1
|
Homo sapiens (human)
|
|
Synthesis of 15-eicosatetraenoic acid derivatives
|
|
|
- ALOX15
- ALOX15B
- COX2
- GPX1
- GPX2
- GPX4
- LOG15
- PTGS2
|
Homo sapiens (human)
|
|
Beta oxidation of octanoyl-CoA to hexanoyl-CoA
|
|
|
- ACADM
- ECHS1
- HAD
- HAD1
- HADH
- HADHA
- HADHB
- HADHSC
- SCHAD
|
Homo sapiens (human)
|
|
LXRs regulate gene expression linked to cholesterol transport and efflux
|
|
|
- ABC1
- ABC8
- ABCA1
- ABCG1
- ABCG5
- ABCG8
- AGO1
- AGO2
- AGO3
- AGO4
- AOF1
- AOF2
- APC2
- APOC1
- APOC2
- APOC4
- APOD
- APOE
- ARL4C
- ARL7
- BHLHE74
- C6orf193
- CAGH26
- CERP
- CETP
- CTG26
- EEPD1
- EIF2C1
- EIF2C2
- EIF2C3
- EIF2C4
- EP300
- GPS2
- HDAC3
- IRA1
- JHDM2A
- JHDM3A
- JMJD1
- JMJD1A
- JMJD2
- JMJD2A
- KDM1
- KDM1A
- KDM1B
- KDM3A
- KDM4A
- KIAA0601
- KIAA0677
- KIAA0742
- KIAA1047
- KIAA1093
- KIAA1460
- KIAA1567
- KIAA1582
- KIAA1631
- KIAA1706
- LSD1
- LSD2
- LXRA
- LXRB
- MOV10
- NCOA1
- NCOR1
- NCOR2
- NER
- NR1H2
- NR1H3
- NR2B1
- NR2B2
- P300
- RXRA
- RXRB
- SRC1
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TNRC6
- TNRC6A
- TNRC6B
- TNRC6C
- TSGA
- UNR
- WHT1
|
Homo sapiens (human)
|
|
Telomere C-strand (Lagging Strand) Synthesis
|
|
|
- ACD
- DRIP5
- KIAA0039
- PCNA
- PIN2
- PIP1
- POLD
- POLD1
- POLD2
- POLD3
- POLD4
- POLDS
- POT1
- PTOP
- RAP1
- TERF1
- TERF2
- TERF2IP
- TIN2
- TINF2
- TINT1
- TPP1
- TRBF1
- TRBF2
- TRF
- TRF1
- TRF2
|
Homo sapiens (human)
|
|
Regulation of RUNX2 expression and activity
|
|
|
- ADRM1
- BAPX1
- BHLHA38
- BMP2
- BMP2A
- C7orf76
- CBFB
- CHIP
- CUL1
- DLX5
- DLX6
- DSS1
- EMC19
- ERR1
- ESR
- ESR1
- ESRL1
- ESRRA
- FBXL1
- GP110
- GRL
- GSK3B
- HC2
- HC3
- HC8
- HC9
- HIVEP3
- HOX8
- HSPC
- KBP1
- KIAA0107
- KIAA1555
- KIAA1625
- KRC
- LEM6
- LMPX
- LMPY
- MB1
- MIP224
- MOV34L
- MSS1
- MSX2
- NKX3-2
- NKX3B
- NR3A1
- NR3B1
- NR3C1
- NU
- OCP2
- PERC
- PFAAP4
- PGC1
- PGC1A
- PGC1B
- POH1
- PPARGC1
- PPARGC1A
- PPARGC1B
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RBX1
- RNF75
- ROC1
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SKP1
- SKP1A
- SKP2
- SMURF1
- STAT1
- STUB1
- SUG1
- SUG2
- TBP1
- TBP7
- TCEB1L
- TRAP2
- TWIST
- TWIST1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WWP1
- X
- Y
- Z
- ZAS3
|
Homo sapiens (human)
|
|
Dasatinib-resistant KIT mutants
|
|
|
|
Homo sapiens (human)
|
|
Phosphorylation of Emi1
|
|
|
- CCNB
- CCNB1
- CDC2
- CDC20
- CDC28A
- CDH1
- CDK1
- CDKN1
- EMI1
- FBX5
- FBXO5
- FYR
- FZR
- FZR1
- KIAA1242
- P34CDC2
- PLK
- PLK1
|
Homo sapiens (human)
|
|