GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1826 - 1850** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
Signaling by NTRK3 (TRKC)	NT-3 growth factor receptor Neurotrophin-3 Receptor-type tyrosine-protein phosphatase O Receptor-type tyrosine-protein phosphatase S	P20783 Q13332 Q16288 Q16827	GLEPP1 NTF3 NTRK3 PTPRO PTPRS PTPU2 TRKC	Homo sapiens (human)
KIT mutants bind TKIs	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Regulation of PTEN stability and activity	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase NEDD4 E3 ubiquitin-protein ligase RNF146 E3 ubiquitin-protein ligase XIAP E3 ubiquitin-protein ligase makorin-1 NEDD4-like E3 ubiquitin-protein ligase WWP2 OTU domain-containing protein 3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Tyrosine-protein kinase FRK Ubiquitin carboxyl-terminal hydrolase 13 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein RFP	O00231 O00232 O00308 O00487 O14818 O43242 O95271 P0CG47 P0CG48 P14373 P17980 P19784 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P31749 P31751 P35998 P42685 P43686 P46934 P48556 P49720 P49721 P51665 P60484 P60896 P60900 P62191 P62195 P62333 P62979 P62987 P67870 P68400 P98170 Q13200 Q15008 Q16186 Q5T2D3 Q70Z35 Q92995 Q99436 Q99460 Q9H2K2 Q9NTX7 Q9UHC7 Q9UNE7 Q9UNM6 Q9Y243	ADRM1 AKT1 AKT2 AKT3 API3 BIRC4 C7orf76 CHIP CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B DEPDC2 DSS1 FRK G5A GP110 HC2 HC3 HC8 HC9 HSPC IAP3 ISOT3 KIAA0093 KIAA0107 KIAA0459 LMPX LMPY MB1 MIP224 MKRN1 MMAC1 MOV34L MSS1 NEDD4 NEDD4-1 NU OTUD3 PARP5A PARP5B PARPL PFAAP4 PKB PKBG POH1 PREX2 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTEN PTK5 RAC RAK RFP RNF146 RNF61 RNF76 RPF1 RPS27A SEM1 SHFDG1 SHFM1 STUB1 SUG1 SUG2 TANK2 TBP1 TBP7 TEP1 TIN1 TINF1 TNKL TNKS TNKS1 TNKS2 TRAP2 TRIM27 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP13 WWP2 X XIAP Y Z	Homo sapiens (human)
Sialic acid metabolism	Alpha-2,8-sialyltransferase 8B Alpha-2,8-sialyltransferase 8E Alpha-2,8-sialyltransferase 8F Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 1 Beta-galactoside alpha-2,6-sialyltransferase 2 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase CMP-sialic acid transporter Lactosylceramide alpha-2,3-sialyltransferase Lysosomal protective protein N-acetylneuraminate lyase N-acylneuraminate cytidylyltransferase N-acylneuraminate-9-phosphatase Sialic acid synthase Sialidase-1 Sialidase-2 Sialidase-3 Sialidase-4 Sialin Type 2 lactosamine alpha-2,3-sialyltransferase	O15466 O43173 P10619 P15907 P16278 P61647 P78382 Q11201 Q11203 Q11206 Q16842 Q8NDV1 Q8NFW8 Q8TBE9 Q8WWR8 Q92185 Q92186 Q92187 Q969X2 Q96JF0 Q99519 Q9BVH7 Q9BXD5 Q9H4F1 Q9NR45 Q9NRA2 Q9NSC7 Q9UJ37 Q9UNP4 Q9UQ49 Q9Y223 Q9Y274 Q9Y3R4	C1orf13 C20orf147 CGS23 CMAS CTSA ELNR1 GLB1 GLCNE GNE HDHD4 IBM2 KIAA1877 NANH NANP NANS NANTA3 NEU1 NEU2 NEU3 NEU4 NPL PPGB PST PST1 SAS SIAT1 SIAT10 SIAT2 SIAT3C SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SIAT7A SIAT7B SIAT7C SIAT7D SIAT7E SIAT7F SIAT8 SIAT8A SIAT8B SIAT8C SIAT8D SIAT8E SIAT8F SIAT9 SIATL1 SLC17A5 SLC35A1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL1 ST6GAL2 ST6GALNAC1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA2 ST8SIA3 ST8SIA4 ST8SIA5 ST8SIA6 STHM STX STZ	Homo sapiens (human)
Differentiation of keratinocytes in interfollicular epidermis in mammalian skin	Pro-epidermal growth factor	P01133	EGF	Homo sapiens (human)
Resistance of ERBB2 KD mutants to trastuzumab	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Electron transport from NADPH to Ferredoxin	Adrenodoxin, mitochondrial Ferredoxin-2, mitochondrial NADPH	P10109 P22570 Q6P4F2	ADX ADXR FDX1 FDX1L FDX2 FDXR	Homo sapiens (human)
Nicotinate metabolism	5'-nucleotidase ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 Glutamine-dependent NAD(+) synthetase NAD kinase 2, mitochondrial NAD kinase Nicotinamide riboside kinase 1 Nicotinamide riboside kinase 2 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 Nicotinate-nucleotide pyrophosphorylase [carboxylating]	O95544 P21589 P28907 Q10588 Q15274 Q4G0N4 Q6IA69 Q96T66 Q9BZQ4 Q9HAN9 Q9NPI5 Q9NWW6	BST1 C1orf15 C5orf33 C9orf95 CD38 ITGB1BP3 KIAA0479 MNADK NADK NADK2 NADKD1 NADSYN1 NMNAT NMNAT1 NMNAT2 NMNAT3 NMRK1 NMRK2 NRK1 NRK2 NT5 NT5E NTE QPRT	Homo sapiens (human)
Smooth Muscle Contraction	Aldehyde dehydrogenase, mitochondrial Annexin A1 Annexin A2 Annexin A6 Caldesmon Calmodulin-1 Caveolin-3 Dysferlin Guanylate cyclase soluble subunit alpha-1 Guanylate cyclase soluble subunit alpha-2 Guanylate cyclase soluble subunit beta-1 Guanylate cyclase soluble subunit beta-2 Integrin alpha-1 Integrin beta-5 Leiomodin-1 Myosin light chain 5 Myosin light chain 6B Myosin light chain kinase, smooth muscle Myosin light polypeptide 6 Myosin regulatory light chain 10 Myosin regulatory light chain 11 Myosin regulatory light chain 12A Myosin regulatory light chain 12B Myosin regulatory light chain 2, atrial isoform Myosin regulatory light polypeptide 9 Myosin-11 Paxillin Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Sorbin and SH3 domain-containing protein 1 Talin-1 Tripartite motif-containing protein 72 Tropomyosin alpha-1 chain Tropomyosin alpha-3 chain Tropomyosin alpha-4 chain Tropomyosin beta chain Vinculin Vinexin Voltage-dependent T-type calcium channel subunit alpha-1G Voltage-dependent T-type calcium channel subunit alpha-1H Voltage-dependent T-type calcium channel subunit alpha-1I cGMP-specific 3',5'-cyclic phosphodiesterase	O14950 O43497 O60504 O75343 O75923 O76074 O95180 P04083 P05091 P06753 P07355 P07951 P08133 P09493 P0DP23 P14649 P18084 P18206 P19105 P24844 P29536 P33402 P35749 P49023 P56199 P56539 P60660 P67936 Q01449 Q02045 Q02108 Q02153 Q05682 Q13153 Q13177 Q15746 Q6ZMU5 Q96A32 Q9BUA6 Q9BX66 Q9P0X4 Q9Y490	ALDH2 ALDM ANX1 ANX2 ANX2L4 ANX6 ANXA1 ANXA2 ANXA6 C15orf13 CACNA1G CACNA1H CACNA1I CAD CAL1H CALD1 CALM CALM1 CAM CAM1 CAV3 CDM DYSF FER1L1 GUC1A2 GUC1A3 GUC1B3 GUCSA2 GUCSA3 GUCSB3 GUCY1A1 GUCY1A2 GUCY1A3 GUCY1B1 GUCY1B2 GUCY1B3 HSRLC ITGA1 ITGB5 KIAA0866 KIAA0894 KIAA1027 KIAA1120 KIAA1123 KIAA1296 LMOD1 LPC1 LPC2D MG53 MLC1SA MLC2 MLCB MLCK MLCK1 MRLC1 MRLC2 MRLC3 MYH11 MYL10 MYL11 MYL12A MYL12B MYL2A MYL5 MYL6 MYL6B MYL7 MYL9 MYLC2A MYLC2B MYLC2PL MYLK MYLK1 MYLPF MYRL2 PAK1 PAK2 PDE5 PDE5A PLRLC PXN RLC SCAM1 SH3D5 SORBS1 SORBS3 TLN TLN1 TMSA TMSB TPM1 TPM2 TPM3 TPM4 TRIM72 VCL	Homo sapiens (human)
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein C Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere protein W Centromere protein X Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3-like centromeric protein A Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Holliday junction recognition protein Kinetochore scaffold 1 Mis18-binding protein 1 Nucleophosmin Protein Mis18-alpha Protein Mis18-beta Remodeling and spacing factor 1 RuvB-like 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	A8MT69 O43482 O60264 O60814 P04908 P06748 P06899 P0C5Y9 P16104 P20671 P23527 P33778 P49450 P57053 P58876 P62805 P62807 Q03188 Q09028 Q13352 Q16576 Q16777 Q16778 Q5EE01 Q6FI13 Q6IPU0 Q6P0N0 Q71F23 Q71UI9 Q7L2Z9 Q8N0S6 Q8N257 Q8N2Z9 Q8NCD3 Q8NG31 Q92674 Q93077 Q93079 Q96A08 Q96BT3 Q96H22 Q96T23 Q99877 Q99878 Q99879 Q99880 Q9BS16 Q9BTM1 Q9BU64 Q9H3R5 Q9NSP4 Q9NYP9 Q9Y265	APITD1 C14orf106 C16orf56 C16orf60 C1orf155 C21orf45 C21orf46 C22orf18 C6orf139 C6orf173 CASC5 CENPA CENPC CENPC1 CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CENPW CENPX CUG2 FAAP10 FAAP16 FAKTS FASP1 FLEG1 FSHPRH1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HBXAP HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HJURP ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INO80H ITGB3BP KIAA1570 KIAA1903 KLIP1 KNL1 KNL2 LRPR1 M18BP1 MCM21R MHF1 MHF2 MIS18A MIS18B MIS18BP1 MLF1IP NMP238 NPM NPM1 NRIF3 OIP5 PANE1 PBIP1 RBAP46 RBAP48 RBBP4 RBBP7 RSF1 RUVBL1 SMARCA5 SNF2H STRA13 TIP49 TIP49A TSH2B URLC9 WCRF135 XAP8	Homo sapiens (human)
Myogenesis	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 C-Jun-amino-terminal kinase-interacting protein 4 Cadherin-15 Cadherin-2 Cadherin-4 Catenin alpha-1 Catenin alpha-2 Catenin beta-1 Cell adhesion molecule-related/down-regulated by oncogenes Cell division control protein 42 homolog Dual specificity mitogen-activated protein kinase kinase 6 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 14 Myoblast determination protein 1 Myocyte-specific enhancer factor 2A Myocyte-specific enhancer factor 2B Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D Myogenic factor 5 Myogenic factor 6 Myogenin Neogenin Netrin-3 Transcription factor 12 Transcription factor 4 Transcription factor E2-alpha Tyrosine-protein kinase ABL1	O00634 O60271 P00519 P13349 P15172 P15173 P15884 P15923 P19022 P23409 P26232 P35221 P35222 P52564 P53778 P55283 P55291 P60953 Q02078 Q02080 Q06413 Q12982 Q14814 Q15759 Q16539 Q4KMG0 Q92859 Q99081	ABL ABL1 BHLHB19 BHLHB20 BHLHB21 BHLHC1 BHLHC2 BHLHC3 BHLHC4 BNIP2 CAPR CDC42 CDH14 CDH15 CDH2 CDH3 CDH4 CDHN CDO CDON CSBP CSBP1 CSBP2 CSPB1 CTNNA1 CTNNA2 CTNNB CTNNB1 E2A ERK6 HEB HSS HTF4 IGDCC2 ITF1 ITF2 JTK7 KIAA0516 MAP2K6 MAPK11 MAPK12 MAPK14 MAPK8IP4 MEF2 MEF2A MEF2B MEF2C MEF2D MEK6 MKK6 MRF4 MXI2 MYF3 MYF4 MYF5 MYF6 MYOD MYOD1 MYOG NCAD NEO1 NGN NIP2 NTN2L NTN3 PRKM11 PRKMK6 SAPK2 SAPK2A SAPK2B SAPK3 SEF2 SKK3 SPAG9 SYD1 TCF12 TCF3 TCF4 XMEF2	Homo sapiens (human)
Gap junction assembly	Gap junction alpha-1 protein Gap junction alpha-10 protein Gap junction alpha-3 protein Gap junction alpha-4 protein Gap junction alpha-5 protein Gap junction alpha-8 protein Gap junction alpha-9 protein Gap junction beta-1 protein Gap junction beta-2 protein Gap junction beta-3 protein Gap junction beta-4 protein Gap junction beta-5 protein Gap junction beta-6 protein Gap junction beta-7 protein Gap junction delta-2 protein Gap junction delta-3 protein Gap junction delta-4 protein Gap junction gamma-1 protein Gap junction gamma-2 protein	O75712 O95377 O95452 P08034 P17302 P29033 P35212 P36382 P36383 P48165 P57773 Q5T442 Q6PEY0 Q8N144 Q969M2 Q96KN9 Q9NTQ9 Q9UKL4 Q9Y6H8	CX25 CX31 CX32 CX40.1 CX62 GJA1 GJA10 GJA11 GJA12 GJA3 GJA4 GJA5 GJA7 GJA8 GJA9 GJAL GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 GJC1 GJC2 GJD2 GJD3 GJD4	Homo sapiens (human)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	ATP-dependent DNA/RNA helicase DHX36 ATP-dependent RNA helicase A Interferon regulatory factor 7 Myeloid differentiation primary response protein MyD88 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P19838 Q00653 Q04206 Q08211 Q92985 Q99836 Q9H2U1	DDX36 DDX9 DHX36 DHX9 IRF7 KIAA1488 LKP LYT10 MLEL1 MYD88 NDH2 NFKB1 NFKB2 NFKB3 RELA RHAU	Homo sapiens (human)
Cristae formation	ATP synthase F(0) complex subunit B1, mitochondrial ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase F(0) complex subunit C2, mitochondrial ATP synthase F(0) complex subunit C3, mitochondrial ATP synthase membrane subunit K, mitochondrial ATP synthase protein 8 ATP synthase subunit ATP5MJ, mitochondrial ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit delta, mitochondrial ATP synthase subunit e, mitochondrial ATP synthase subunit epsilon, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase subunit s, mitochondrial ATP synthase-coupling factor 6, mitochondrial DnaJ homolog subfamily C member 11 MICOS complex subunit MIC10 MICOS complex subunit MIC13 MICOS complex subunit MIC19 MICOS complex subunit MIC25 MICOS complex subunit MIC26 MICOS complex subunit MIC27 MICOS complex subunit MIC60 Metaxin-1 Metaxin-2 Sorting and assembly machinery component 50 homolog Stress-70 protein, mitochondrial Transmembrane protein 11, mitochondrial	O75431 O75947 O75964 P00846 P03928 P05496 P06576 P17152 P18859 P24539 P25705 P30049 P36542 P38646 P48047 P48201 P56134 P56378 P56381 P56385 Q06055 Q13505 Q16891 Q5TGZ0 Q5XKP0 Q6UXV4 Q96IX5 Q99766 Q9BRQ6 Q9BUR5 Q9NVH1 Q9NX63 Q9Y512	APOO APOOL ATP5A ATP5A1 ATP5AL2 ATP5B ATP5C ATP5C1 ATP5CL1 ATP5D ATP5E ATP5F1 ATP5F1A ATP5F1B ATP5F1C ATP5F1D ATP5F1E ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2 ATP5JL ATP5K ATP5L ATP5MC1 ATP5MC2 ATP5MC3 ATP5MD ATP5ME ATP5MF ATP5MG ATP5MJ ATP5MK ATP5MPL ATP5O ATP5PB ATP5PD ATP5PF ATP5PO ATP5S ATP6 ATP8 ATPASE6 ATPASE8 ATPM ATPMB ATPO ATPSB ATPW C14orf2 C17orf35 C19orf70 C1orf151 CHCHD3 CHCHD6 CHCM1 CXorf33 DAPIT DMAC2L DNAJC11 FAM121A FAM121B GRP75 HCVFTP2 HMP HSPA9 HSPA9B IMMT MIC10 MIC13 MIC19 MIC23 MIC25 MIC26 MIC27 MIC60 MICOS10 MICOS13 MINOS1 MINOS2 MINOS3 MP68 MT-ATP6 MT-ATP8 MTATP6 MTATP8 MTX MTX1 MTX2 MTXN PM1 QIL1 SAM50 SAMM50 TMEM11 USMG5 mt-HSP70	Homo sapiens (human)
Regulation of signaling by CBL	Adapter molecule crk B-cell linker protein Crk-like protein E3 ubiquitin-protein ligase CBL Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Proto-oncogene vav Rap guanine nucleotide exchange factor 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes	O00329 O00459 P06241 P07947 P07948 P08631 P15498 P22681 P27986 P42336 P42338 P43405 P46108 P46109 Q13905 Q8WV28 Q92569	BASH BLNK CBL CBL2 CRK CRKL FYN GRB1 GRF2 HCK JTK8 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 RAPGEF1 RNF55 SLP65 SYK VAV VAV1 YES YES1	Homo sapiens (human)
Cholesterol biosynthesis	3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 Acetyl-CoA acetyltransferase, cytosolic Delta(14)-sterol reductase LBR Delta(14)-sterol reductase TM7SF2 Delta(24)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase, cytoplasmic Isopentenyl-diphosphate Delta-isomerase 1 Isopentenyl-diphosphate delta-isomerase 2 Lanosterol 14-alpha demethylase Lanosterol synthase Methylsterol monooxygenase 1 Mevalonate kinase Phosphomevalonate kinase Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 Protein ARV1 Squalene monooxygenase Squalene synthase Sterol regulatory element-binding protein 1 Sterol regulatory element-binding protein 2 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	O76062 O95749 P14324 P36956 P37268 P48449 P53602 P56937 Q01581 Q03426 Q12772 Q13907 Q14534 Q14739 Q15126 Q15392 Q15738 Q15800 Q16850 Q8IY26 Q9BWD1 Q9BXS1 Q9H2C2	17HSD7 ACAT2 ACTL ANG1 ARV1 BHLHD1 BHLHD2 CYP51 CYP51A1 DESP4 DHCR24 ERG1 ERG25 FDFT1 FDPS FPS GGPS1 H105E3 HMGCS HMGCS1 HSD17B7 IDI1 IDI2 KIAA0018 KIAA1293 LBR LSS MPD MSMO1 MVD MVK NSDHL OSC PDP1 PLPP6 PMKI PMVK PPAPDC2 SC4MOL SDR37C1 SQLE SREBF1 SREBF2 SREBP1 SREBP2 TM7SF2	Homo sapiens (human)
NoRC negatively regulates rRNA expression	AT-rich interactive domain-containing protein 4B Bromodomain adjacent to zinc finger domain protein 2A CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA (cytosine-5)-methyltransferase 1 DNA (cytosine-5)-methyltransferase 3B DNA-directed RNA polymerase I subunit RPA12 DNA-directed RNA polymerase I subunit RPA1 DNA-directed RNA polymerase I subunit RPA2 DNA-directed RNA polymerase I subunit RPA34 DNA-directed RNA polymerase I subunit RPA43 DNA-directed RNA polymerase I subunit RPA49 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase complex subunit SAP130 Histone deacetylase complex subunit SAP18 Histone deacetylase complex subunit SAP30 Histone deacetylase complex subunit SAP30L Methyl-CpG-binding domain protein 2 Nucleolar transcription factor 1 Paired amphipathic helix protein Sin3a Paired amphipathic helix protein Sin3b Protein POLR1D, isoform 2 SAP30-binding protein SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 Sin3 histone deacetylase corepressor complex component SDS3 TATA box-binding protein-associated factor RNA polymerase I subunit A TATA box-binding protein-associated factor RNA polymerase I subunit B TATA box-binding protein-associated factor RNA polymerase I subunit C TATA box-binding protein-associated factor RNA polymerase I subunit D TATA-box-binding protein Transcription termination factor 1	O00422 O15160 O15446 O60264 O60814 O75182 O75446 O95602 P04908 P06899 P0C5Y9 P0DPB5 P16104 P17480 P18074 P19388 P19447 P20226 P20671 P23527 P26358 P32780 P33778 P50613 P51946 P51948 P52434 P53803 P57053 P58876 P61218 P62805 P62807 P62875 P68431 P84243 Q13547 Q13888 Q13889 Q15361 Q15572 Q15573 Q16777 Q16778 Q3B726 Q4LE39 Q53T94 Q6FI13 Q6ZYL4 Q71DI3 Q71UI9 Q8N257 Q92759 Q92769 Q93077 Q93079 Q96A08 Q96ST3 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9GZS1 Q9H0E3 Q9H5J8 Q9H7L9 Q9H9Y6 Q9HAJ7 Q9P1U0 Q9UBB5 Q9UBC3 Q9UHR5 Q9UIF9	AIM ARID4B ASE1 BAZ2A BRCAA1 BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CAST CCNH CD3EAP CDK7 CDKN7 CXXC9 DNMT DNMT1 DNMT3B ERCC2 ERCC3 GTF2D1 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HCNGP HDAC1 HDAC2 HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HTRG HTRP JOSD3 KIAA0314 KIAA0700 MAT1 MBD2 MNAT1 MO15 NS4ATP2 PAF49 PAF53 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1F POLR1G POLR1H POLR2E POLR2F POLR2H POLR2K POLR2L POLRF PRAF1 RBBP1L1 RBP1L1 RNF66 RPA12 RPD3L1 SAP130 SAP18 SAP180 SAP30 SAP30BP SAP30L SAP45 SDS3 SIN3A SIN3B SMARCA5 SNF2H STK1 SUDS3 TAF1A TAF1B TAF1C TAF1D TBP TF2D TFIID TIP5 TSH2B TTDA TTF1 TWISTNB UBF UBF1 UBTF WCRF135 XPB XPBC XPD XPDC ZNRD1	Homo sapiens (human)
Glycerophospholipid biosynthesis	Acylglycerol kinase, mitochondrial Copine-1 Copine-3 Copine-6 Copine-7	O75131 O95741 Q53H12 Q99829 Q9UBL6	AGK CPN1 CPN3 CPNE1 CPNE3 CPNE6 CPNE7 KIAA0636 MULK	Homo sapiens (human)
Drug resistance in ERBB2 TMD/JMD mutants	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Regulation of PTEN localization	E3 ubiquitin-protein ligase NEDD4 E3 ubiquitin-protein ligase XIAP Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Polyubiquitin-B Polyubiquitin-C Protein PML Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P29590 P46934 P60484 P62979 P62987 P98170 Q93009	API3 BIRC4 HAUSP IAP3 KIAA0093 MMAC1 MYL NEDD4 NEDD4-1 PML PP8675 PTEN RNF71 RPF1 RPS27A TEP1 TRIM19 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 XIAP	Homo sapiens (human)
ADP signalling through P2Y purinoceptor 12	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 P2Y purinoceptor 12	A8MTJ3 O14610 O14775 O60262 P04899 P08754 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63096 P63211 P63215 P63218 Q9H244 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	GNAI1 GNAI2 GNAI2B GNAI3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 HORK3 P2RY12	Homo sapiens (human)
Chylomicron clearance	Apolipoprotein B-100 Apolipoprotein E Hepatic triacylglycerol lipase Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor	P01130 P02649 P04114 P11150 Q5SW96	APOB APOE ARH HTGL LDLR LDLRAP1 LIPC	Homo sapiens (human)
Loss of MECP2 binding ability to 5mC-DNA	Histone deacetylase 1 Paired amphipathic helix protein Sin3a	Q13547 Q96ST3	HDAC1 RPD3L1 SIN3A	Homo sapiens (human)
TRAF6 mediated NF-kB activation	Advanced glycosylation end product-specific receptor Amyloid-beta precursor protein Antiviral innate immune response receptor RIG-I E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Mitogen-activated protein kinase kinase kinase 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor-interacting Ras-like protein 1 NF-kappa-B inhibitor-interacting Ras-like protein 2 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Protein S100-A12 Protein S100-B Serum amyloid A-1 protein TNF receptor-associated factor 2 TNF receptor-associated factor 6 Transcription factor p65	O14920 O15111 O95786 P04271 P05067 P09429 P0DJI8 P19838 P25963 P80511 Q00653 Q04206 Q12933 Q13233 Q14258 Q15109 Q15653 Q7Z434 Q8IUD6 Q9BYX4 Q9C037 Q9NYR9 Q9NYS0 Q9Y4K3 Q9Y6K9	A4 AD1 AGER APP CHUK DDX58 EFP FIP3 HMG1 HMGB1 IFIH1 IKBA IKBB IKBKB IKBKG IKKA IKKB IPS1 KBRAS1 KBRAS2 KIAA1271 LYT10 MAD3 MAP3K1 MAPKKK1 MAVS MDA5 MEKK MEKK1 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA NFKBIB NKIRAS1 NKIRAS2 RAGE RELA RH116 RIGI RNF135 RNF147 RNF85 RNF87 S100A12 S100B SAA1 TCF16 TRAF2 TRAF6 TRAP3 TRIM25 TRIM4 TRIP9 VISA ZNF147	Homo sapiens (human)
Amino acid transport across the plasma membrane	Amino acid transporter heavy chain SLC3A1 Amino acid transporter heavy chain SLC3A2 Asc-type amino acid transporter 1 Cationic amino acid transporter 3 Cystine/glutamate transporter High affinity cationic amino acid transporter 1 Inactive sodium-dependent neutral amino acid transporter B(0)AT3 Large neutral amino acids transporter small subunit 1 Large neutral amino acids transporter small subunit 2 Large neutral amino acids transporter small subunit 3 Large neutral amino acids transporter small subunit 4 Mitochondrial basic amino acids transporter Monocarboxylate transporter 10 Neutral amino acid transporter A Neutral amino acid transporter B(0) Neutral amino acid uniporter 4 Proton-coupled amino acid transporter 1 Proton-coupled amino acid transporter 2 Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) Sodium- and chloride-dependent taurine transporter Sodium- and chloride-dependent transporter XTRP3 Sodium-coupled neutral amino acid symporter 1 Sodium-coupled neutral amino acid symporter 2 Sodium-coupled neutral amino acid transporter 3 Sodium-coupled neutral amino acid transporter 4 Sodium-coupled neutral amino acid transporter 5 Sodium-dependent neutral amino acid transporter B(0)AT1 Sodium-dependent neutral amino acid transporter B(0)AT2 Y+L amino acid transporter 1 Y+L amino acid transporter 2 b(0,+)-type amino acid transporter 1	O75387 P08195 P30825 P31641 P43007 P48065 P82251 Q01650 Q07837 Q15758 Q495M3 Q695T7 Q6YBV0 Q7Z2H8 Q8N370 Q8N8R3 Q8TF71 Q8WUX1 Q8WY07 Q92536 Q969I6 Q96N87 Q96QD8 Q99624 Q9H2H9 Q9H2J7 Q9NP91 Q9NS82 Q9UHI5 Q9UM01 Q9UN76 Q9UPY5	ASC1 ASCT1 ASCT2 ATA1 ATA2 ATA3 ATRC1 ATRC3 B0AT1 B0AT2 B0AT3 BAT1 BGT1 C14orf69 CAT3 CD98LC ERR G17 JM24 KIAA0245 KIAA1382 LAT1 LAT2 LAT3 LAT4 M7V1 MCT10 MDU1 MPE16 NAT1 NAT2 NAT3 NBAT NTT73 ORNT3 PAT1 PAT2 PAT4 PB39 POV1 RDR RDRC REC1L SAT1 SAT2 SATT SBAT1 SIT1 SLC16A10 SLC1A4 SLC1A5 SLC25A29 SLC36A1 SLC36A2 SLC36A4 SLC38A1 SLC38A2 SLC38A3 SLC38A4 SLC38A5 SLC3A1 SLC3A2 SLC43A1 SLC43A2 SLC6A12 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A20 SLC6A6 SLC7A1 SLC7A10 SLC7A11 SLC7A3 SLC7A5 SLC7A6 SLC7A7 SLC7A8 SLC7A9 SN1 SN2 SNAT1 SNAT2 SNAT3 SNAT4 SNAT5 TAT1 TRAMD1 XT3 XTRP2 XTRP3	Homo sapiens (human)

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