Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
cystic fibrosis

Summary
Synonym
  • CF
  • mucoviscidosis
Definition
A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.
Super Class
autosomal recessive disease syndrome
Disease Ontology
DOID:1485
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 72 in total
Gene ID Gene Symbol Description Source
1080 CFTR CF transmembrane conductance regulator
1179 CLCA1 chloride channel accessory 1
1181 CLCN2 chloride voltage-gated channel 2
1232 CCR3 C-C motif chemokine receptor 3
1441 CSF3R colony stimulating factor 3 receptor
1543 CYP1A1 cytochrome P450 family 1 subfamily A member 1
1906 EDN1 endothelin 1
2212 FCGR2A Fc gamma receptor IIa
2729 GCLC glutamate-cysteine ligase catalytic subunit
2833 CXCR3 C-X-C motif chemokine receptor 3
Displaying entries 1 - 10 of 78 in total
Gene ID Gene Symbol Description Source
11554 Adrb1 adrenergic receptor, beta 1
11555 Adrb2 adrenergic receptor, beta 2
11556 Adrb3 adrenergic receptor, beta 3
11596 Ager advanced glycosylation end product-specific receptor
12475 Cd14 CD14 antigen
12638 Cftr cystic fibrosis transmembrane conductance regulator
12724 Clcn2 chloride channel, voltage-sensitive 2
12766 Cxcr3 C-X-C motif chemokine receptor 3
12986 Csf3r colony stimulating factor 3 receptor
13076 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
Displaying entries 11 - 20 of 43 in total
Gene ID Gene Symbol Description Source
24795 Serpina3n serpin family A member 3N
24835 Tnf tumor necrosis factor
24891 Abcb4 ATP binding cassette subfamily B member 4
24925 Adrb1 adrenoceptor beta 1
25008 Lta lymphotoxin alpha
25283 Gclc glutamate-cysteine ligase, catalytic subunit
25350 Sftpd surfactant protein D
25385 Faslg Fas ligand
25608 Lep leptin
25645 Adrb3 adrenoceptor beta 3
Displaying all 9 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
34714 Edem2 ER degradation enhancer, mannosidase alpha-like 2
36428 Mdr49 Multi drug resistance 49
38326 Pxn Peroxidasin
38726 Mdr65 Multi drug resistance 65
41549 Octbeta2R Octopamine beta2 receptor
42652 Octbeta1R Octopamine beta1 receptor
43222 Tl Toll
47905 l(2)03659 lethal (2) 03659
Displaying all 3 entries
Gene ID Gene Symbol Description Source
403139 tlr5b toll-like receptor 5b
559080 cftr CF transmembrane conductance regulator
791973 cxcr3.2 chemokine (C-X-C motif) receptor 3, tandem duplicate 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
108697308 adrb1.L adrenoceptor beta 1 L homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
174821 clh-1 CBS domain-containing protein
177857 C47E12.3 alpha-1,2-Mannosidase
178215 pgp-1 Multidrug resistance protein pgp-1
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
181101 mec-10 Degenerin mec-10
181288 pxn-2 Peroxidasin homolog pxn-2
181326 pgp-3 Multidrug resistance protein pgp-3
181728 mec-4 Degenerin mec-4
Displaying all 4 entries
Gene ID Gene Symbol Description Source
853198 YOR1 ATP-binding cassette transporter YOR1
853671 STE6 ATP-binding cassette a-factor transporter STE6
853978 NFT1 putative multidrug transporter NFT1
856611 MNL1 alpha-1,2-mannosidase MNL1
The Human Phenotype Ontology
Displaying entries 11 - 20 of 32 in total
HPO ID HPO Term
HP:0003251 Male infertility
HP:0001508 Failure to thrive
HP:0012236 Elevated sweat chloride
HP:0002035 Rectal prolapse
HP:0000938 Osteopenia
HP:0002726 Recurrent Staphylococcus aureus infections
HP:0000246 Sinusitis
HP:0002107 Pneumothorax
HP:0002910 Elevated circulating hepatic transaminase concentration
HP:0001394 Cirrhosis
Displaying 1 entry
Gene ID Gene Symbol Description
4680 CEACAM6 CEA cell adhesion molecule 6
About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.1.0

Last updated: December 9, 2024