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Standards Ontologies Notations
Guidelines
MIRAGE
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
11652 Akt2 thymoma viral proto-oncogene 2
15560 Htr2c 5-hydroxytryptamine (serotonin) receptor 2C
16334 Ins2 insulin II
16367 Irs1 insulin receptor substrate 1
16846 Lep leptin
16847 Lepr leptin receptor
18023 Nfe2l1 nuclear factor, erythroid derived 2,-like 1
18759 Prkci protein kinase C, iota
20526 Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2
20528 Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4
Displaying entries 1 - 10 of 21 in total
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24385 Gck glucokinase
24536 Lepr leptin receptor
24617 Serpine1 serpin family E member 1
24835 Tnf tumor necrosis factor
24889 Cckar cholecystokinin A receptor
25024 Gipr gastric inhibitory polypeptide receptor
25204 Pcsk1 proprotein convertase subtilisin/kexin type 1
25467 Irs1 insulin receptor substrate 1
25608 Lep leptin
Displaying all 2 entries
Gene ID Gene Symbol Description Source
33496 lilli lilliputian
42549 InR Insulin-like receptor
Displaying all 3 entries
Gene ID Gene Symbol Description Source
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
177850 gon-1 A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
856386 LAG1 sphingosine N-acyltransferase LAG1
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
P38703 Ceramide synthase LAG1
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0003584 Late onset
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
Displaying all 6 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
6514 SLC2A2 solute carrier family 2 member 2
2645 GCK glucokinase
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
3990 LIPC lipase C, hepatic type
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025