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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
External Links
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 441 in total
Gene ID Gene Symbol Description Source
175 AGA aspartylglucosaminidase
207 AKT1 AKT serine/threonine kinase 1
208 AKT2 AKT serine/threonine kinase 2
217 ALDH2 aldehyde dehydrogenase 2 family member
229 ALDOB aldolase, fructose-bisphosphate B
231 AKR1B1 aldo-keto reductase family 1 member B
239 ALOX12 arachidonate 12-lipoxygenase, 12S type
240 ALOX5 arachidonate 5-lipoxygenase
248 ALPI alkaline phosphatase, intestinal
249 ALPL alkaline phosphatase, biomineralization associated
Displaying entries 1 - 10 of 54 in total
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
11651 Akt1 thymoma viral proto-oncogene 1
11652 Akt2 thymoma viral proto-oncogene 2
11677 Akr1b1 aldo-keto reductase family 1 member B
11815 Apod apolipoprotein D
12015 Bad BCL2-associated agonist of cell death
12494 Cd38 CD38 antigen
12654 Chi3l1 chitinase 3 like 1
12894 Cpt1a carnitine palmitoyltransferase 1a, liver
14377 G6pc1 glucose-6-phosphatase catalytic subunit 1
Displaying entries 1 - 10 of 50 in total
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24192 Akr1b1 aldo-keto reductase family 1 member B1
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24385 Gck glucokinase
24476 Iapp islet amyloid polypeptide
24483 Igf2 insulin-like growth factor 2
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24536 Lepr leptin receptor
Displaying entries 1 - 10 of 46 in total
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31806 Ogg1 8-oxoguanine DNA glycosylase
31926 Idgf4 Imaginal disc growth factor 4
32974 Zw Zwischenferment
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
35105 Ugt301D1 UDP-glycosyltransferase family 301 member D1
35137 Ugt36F1 UDP-glycosyltransferase family 36 member F1
35138 Ugt36D1 UDP-glycosyltransferase family 36 member D1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
560788 parp1 poly (ADP-ribose) polymerase 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
407879 ppp1cc protein phosphatase 1, catalytic subunit, gamma isozyme Xenopus tropicalis (tropical clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100489505 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 Xenopus tropicalis (tropical clawed frog)
Displaying all 8 entries
Gene ID Gene Symbol Description Source
172509 gpdh-3 putative glycerol-3-phosphate dehydrogenase, mitochondrial
175591 ugt-62 UDP-glucuronosyltransferase
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
176788 aldo-1 Fructose-bisphosphate aldolase 1
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180628 cht-1 putative endochitinase
189173 W03G11.3 Putative alpha-L-fucosidase
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850614 HXK1 hexokinase 1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
851977 CTS2 putative chitinase
852128 EMI2 putative glucokinase
852639 HXK2 hexokinase 2
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
854350 GAC1 protein phosphatase regulator GAC1
Related Glycoprotein
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
2645 GCK glucokinase
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
6514 SLC2A2 solute carrier family 2 member 2
3990 LIPC lipase C, hepatic type
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024