Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
type 2 diabetes mellitus
Summary
- Synonym
-
- NIDDM
- insulin resistance
- non-insulin-dependent diabetes mellitus
- type 2 diabetes
- type II diabetes mellitus
- Definition
- A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
- Super Class
- diabetes mellitus
External Links
- Disease Ontology
- DOID:9352
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- MGI genotype (from TogoID)
-
- 5504442
- 3760281
- 3766122
- 3789135
- 3842791
- 3847120
- 4361710
- 4429442
- 5294956
- 5301577
- 5428893
- 5435319
- 5502687
- 3721145
- 5620891
- 5637560
- 5638149
- 5695740
- 5766495
- 5789257
- 5804115
- 5804125
- 6111393
- 6160731
- 7314952
- 7622052
- 3531404
- 2175101
- 2177705
- 2385750
- 2385751
- 2653988
- 2654708
- 3028851
- 3029380
- 3051529
- 3052685
- 3510669
- 3510670
- 2174965
- 3531409
- 3582680
- 3583344
- 3583687
- 3583763
- 3583951
- 3583952
- 3586490
- 3590085
- 3623394
- 3629188
- 3694548
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3091 | HIF1A | hypoxia inducible factor 1 subunit alpha | |
| 3099 | HK2 | hexokinase 2 | |
| 3117 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | |
| 3156 | HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | |
| 3172 | HNF4A | hepatocyte nuclear factor 4 alpha | |
| 3290 | HSD11B1 | hydroxysteroid 11-beta dehydrogenase 1 | |
| 3304 | HSPA1B | heat shock protein family A (Hsp70) member 1B | |
| 3458 | IFNG | interferon gamma | |
| 3482 | IGF2R | insulin like growth factor 2 receptor | |
| 3486 | IGFBP3 | insulin like growth factor binding protein 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11652 | Akt2 | thymoma viral proto-oncogene 2 | |
| 15560 | Htr2c | 5-hydroxytryptamine (serotonin) receptor 2C | |
| 16334 | Ins2 | insulin II | |
| 16367 | Irs1 | insulin receptor substrate 1 | |
| 16846 | Lep | leptin | |
| 16847 | Lepr | leptin receptor | |
| 18023 | Nfe2l1 | nuclear factor, erythroid derived 2,-like 1 | |
| 18759 | Prkci | protein kinase C, iota | |
| 20526 | Slc2a2 | solute carrier family 2 (facilitated glucose transporter), member 2 | |
| 20528 | Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24185 | Akt1 | AKT serine/threonine kinase 1 | |
| 24385 | Gck | glucokinase | |
| 24536 | Lepr | leptin receptor | |
| 24617 | Serpine1 | serpin family E member 1 | |
| 24835 | Tnf | tumor necrosis factor | |
| 24889 | Cckar | cholecystokinin A receptor | |
| 25024 | Gipr | gastric inhibitory polypeptide receptor | |
| 25204 | Pcsk1 | proprotein convertase subtilisin/kexin type 1 | |
| 25467 | Irs1 | insulin receptor substrate 1 | |
| 25608 | Lep | leptin |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 176000 | ogt-1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase | |
| 177850 | gon-1 | A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein | |
| 266823 | parp-1 | Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P47196 | RAC-alpha serine/threonine-protein kinase | |
| P51639 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | |
| P97629 | Leucyl-cystinyl aminopeptidase | |
| Q62959 | Leptin receptor | |
| Q63495 | Advanced glycosylation end product-specific receptor | |
| Q8K3U6 | Coagulation factor VII | |
| Q8R4Z1 | Serpin A12 | |
| Q9QYK2 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P09208 | Insulin-like receptor | |
| Q9VQI9 | AF4/FMR2 family member lilli |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q19791 | A disintegrin and metalloproteinase with thrombospondin motifs gon-1 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P38703 | Ceramide synthase LAG1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0003584 | Late onset |
| HP:0005978 | Type II diabetes mellitus |
| HP:0000855 | Insulin resistance |
| HP:0000006 | Autosomal dominant inheritance |
| Gene ID | Gene Symbol | Description |
|---|---|---|
| 2820 | GPD2 | glycerol-3-phosphate dehydrogenase 2 |
| 5506 | PPP1R3A | protein phosphatase 1 regulatory subunit 3A |
| 3990 | LIPC | lipase C, hepatic type |
| 6514 | SLC2A2 | solute carrier family 2 member 2 |
| 5167 | ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| 2645 | GCK | glucokinase |
