obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 1 - 10 of 343 in total
Gene ID Gene Symbol Description Source
19 ABCA1 ATP binding cassette subfamily A member 1
32 ACACB acetyl-CoA carboxylase beta
38 ACAT1 acetyl-CoA acetyltransferase 1
51 ACOX1 acyl-CoA oxidase 1
123 PLIN2 perilipin 2
133 ADM adrenomedullin
134 ADORA1 adenosine A1 receptor
154 ADRB2 adrenoceptor beta 2
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
Displaying entries 151 - 160 of 241 in total
Gene ID Gene Symbol Description Source
20411 Sorbs1 sorbin and SH3 domain containing 1
20493 Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1
20525 Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1
20614 Snap25 synaptosomal-associated protein 25
20788 Srebf2 sterol regulatory element binding factor 2
20848 Stat3 signal transducer and activator of transcription 3
20866 Stim1 stromal interaction molecule 1
20969 Sdc1 syndecan 1
20970 Sdc3 syndecan 3
21406 Tcf12 transcription factor 12
Displaying entries 121 - 130 of 151 in total
Gene ID Gene Symbol Description Source
85496 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
94203 Pgf placental growth factor
113936 Cpb2 carboxypeptidase B2
113959 C5ar1 complement C5a receptor 1
113965 Hadh hydroxyacyl-CoA dehydrogenase
114628 Abcg5 ATP binding cassette subfamily G member 5
116510 Timp1 TIMP metallopeptidase inhibitor 1
116550 Atp5f1c ATP synthase F1 subunit gamma
116673 Sdc3 syndecan 3
117261 Slc15a1 solute carrier family 15 member 1
Displaying entries 11 - 20 of 43 in total
Gene ID Gene Symbol Description Source
33726 vkg viking
33727 Col4a1 Collagen type IV alpha 1
33953 nrv2 nervana 2
34009 wg wingless
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
35259 Lar Leukocyte-antigen-related-like
35362 Mtp Microsomal triacylglycerol transfer protein
35728 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 51 in total
Gene ID Gene Symbol Description Source
171782 abt-2 ABC transporter domain-containing protein
171994 lin-44 Abnormal cell lineage protein 44
171999 poml-2 Arylesterase
173169 eif-6 Eukaryotic translation initiation factor 6
173399 cwn-1 Protein Wnt-1
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175201 stim-1 Stromal interaction molecule 1
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850442 SRB8 Srb8p
850614 HXK1 hexokinase 1
850647 PUF3 mRNA-binding protein PUF3
851241 CNE1 calnexin
851888 DPL1 sphinganine-1-phosphate aldolase DPL1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852053 SSN2 Ssn2p
852102 IZH1 PAQR-type receptor
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
9672 SDC3 syndecan 3

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Last updated: December 9, 2024