Purine salvage
|
|
|
- Ada
- Adal
- Adk
- Ampd1
- Ampd2
- Ampd3
- Aprt
- Dck
- Dgk
- Dguok
- Gmpr
- Gmpr1
- Gmpr2
- Hprt
- Hprt1
- Np
- Pnp
- Pnp1
- Pnp2
|
|
Breakdown of the nuclear lamina
|
|
|
- Casp6
- Lmn1
- Lmna
- Lmnb1
- Mch2
|
|
Apoptotic cleavage of cellular proteins
|
|
|
- Acin1
- Acinus
- Apc
- Bap31
- Bcap31
- Birc2
- Bmx
- Casp3
- Casp6
- Casp7
- Casp8
- Clspn
- Cpp32
- Fnta
- Lice2
- Mch2
- Mch3
- Mst3
- Mst4
- Pkcd
- Pkcq
- Prkcd
- Prkcq
- Rock1
- Satb1
- Stk24
- Stk26
- Stk3
|
|
Caspase-mediated cleavage of cytoskeletal proteins
|
|
|
- Add1
- Argbp2
- Casp3
- Casp6
- Casp7
- Casp8
- Cpp32
- Gas-2
- Gas2
- Gsb
- Gsn
- Kiaa0777
- Lice2
- Mapt
- Mch2
- Mch3
- Mtapt
- Plec
- Plec1
- Sorbs2
- Spna2
- Spta2
- Sptan1
- Tau
- Vim
|
|
Release of apoptotic factors from the mitochondria
|
|
|
- Bak
- Bak1
- Bax
- Bh5
- Cycs
- Dfna5
- Dfna5h
- Diablo
- Gm11492
- Gsdmd
- Gsdmdc1
- Gsdme
- Pnutl2
- Sep4
- Sept4
- Septin4
- Smac
|
|
Pyroptosis
|
|
|
- Bak
- Bak1
- Bax
- Casp1
- Casp11
- Casp3
- Casp4
- Caspl
- Chmp2a
- Chmp2b
- Chmp3
- Chmp4b
- Chmp4c
- Chmp6
- Chmp7
- Cpp32
- Ctla-1
- Ctla1
- Cycs
- Dfna5
- Dfna5h
- Ela2
- Elane
- Gsdmd
- Gsdmdc1
- Gsdme
- Gzmb
- Hmg-1
- Hmg1
- Hmgb1
- Ich3
- Igif
- Il18
- Il1a
- Il1b
- Il1bc
- Vps24
|
|
Glycoprotein hormones
|
|
|
- Cga
- Fshb
- Inha
- Inhba
- Inhbb
- Inhbc
- Inhbe
- Lhb
- Tshb
|
|
Triglyceride catabolism
|
|
|
- Ap2
- Blbp
- Fabp1
- Fabp12
- Fabp2
- Fabp3
- Fabp4
- Fabp5
- Fabp6
- Fabp7
- Fabp9
- Fabpe
- Fabph1
- Fabpi
- Fabpl
- Gdm1
- Gpd2
- Illbp
- Klbp
- Mal1
- Perf15
- Pnpla5
- Tlbp
|
|
Detoxification of Reactive Oxygen Species
|
|
|
- Aop1
- Aop2
- Apah1
- Cas-1
- Cas1
- Cat
- Ccs
- Ccsd
- Cgd
- Cyba
- Cybb
- Cycs
- Ero1a
- Ero1l
- Gpx1
- Gpx2
- Gpx3
- Gpx5
- Gpx6
- Gpx7
- Gpx8
- Gr1
- Gsr
- Gstp1
- Gstp2
- Gstpia
- Gstpib
- Ltw4
- Mer5
- Msp23
- Ncf1
- Ncf2
- Ncf4
- Nox4
- Noxa2
- Nudt2
- P4hb
- P67phox
- Paga
- Pdia1
- Prdx1
- Prdx2
- Prdx3
- Prdx5
- Prdx6
- Renox
- Sod-2
- Sod1
- Sod2
- Sod3
- Tdpx1
- Tdpx2
- Tpx
- Trxr1
- Trxr2
- Txn
- Txn1
- Txn2
- Txnrd1
- Txnrd2
|
|
Polo-like kinase mediated events
|
|
|
- Cdc25c
- Cdc25m1
- Fkh16
- Foxm1
- Myt1
- Pkmyt1
- Plk
- Plk1
- Wee1
|
|
Urea cycle
|
|
|
- Arg1
- Arg2
- Asl
- Ass
- Ass1
- Cps1
- Nags
- Nmral1
- Ornt1
- Ornt2
- Otc
- Slc25a15
- Slc25a2
|
|
Mitochondrial protein degradation
|
- 2-oxoglutarate dehydrogenase complex component E1
- 3-hydroxyacyl-CoA dehydrogenase type-2
- 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
- 5-aminolevulinate synthase, non-specific, mitochondrial
- 60 kDa heat shock protein, mitochondrial
- ADP/ATP translocase 2
- ATP synthase subunit O, mitochondrial
- ATP synthase subunit a
- ATP synthase subunit alpha, mitochondrial
- ATP synthase subunit beta, mitochondrial
- ATP synthase subunit d, mitochondrial
- ATP synthase subunit g, mitochondrial
- ATP synthase subunit gamma, mitochondrial
- ATP synthase-coupling factor 6, mitochondrial
- ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
- ATP-dependent Clp protease proteolytic subunit, mitochondrial
- Acetyl-CoA acetyltransferase, mitochondrial
- Aconitate hydratase, mitochondrial
- Acyl-coenzyme A thioesterase 1
- Acyl-coenzyme A thioesterase 2, mitochondrial
- Acyl-coenzyme A thioesterase 3
- Acyl-coenzyme A thioesterase 5
- Aldehyde dehydrogenase X, mitochondrial
- Aldehyde dehydrogenase, mitochondrial
- Amyloid-beta precursor protein
- Arginase-2, mitochondrial
- Citrate synthase, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Cytochrome b-c1 complex subunit 8
- Cytochrome c oxidase subunit 1
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c oxidase subunit 5B, mitochondrial
- D-beta-hydroxybutyrate dehydrogenase, mitochondrial
- Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
- Delta-1-pyrroline-5-carboxylate synthase
- Dihydrolipoyl dehydrogenase, mitochondrial
- Enoyl-CoA delta isomerase 1, mitochondrial
- Essential MCU regulator, mitochondrial
- Ferrochelatase, mitochondrial
- Fumarate hydratase, mitochondrial
- Glutamate dehydrogenase 1, mitochondrial
- Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
- Hydroxymethylglutaryl-CoA synthase, mitochondrial
- Isobutyryl-CoA dehydrogenase, mitochondrial
- Isocitrate dehydrogenase [NADP], mitochondrial
- Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
- Isoleucine--tRNA ligase, mitochondrial
- Large ribosomal subunit protein bL12m
- Large ribosomal subunit protein bL32m
- Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
- Lon protease homolog, mitochondrial
- Malate dehydrogenase, mitochondrial
- Mitochondrial inner membrane m-AAA protease component AFG3L2
- Mitochondrial inner membrane m-AAA protease component paraplegin
- Mitochondrial-processing peptidase subunit alpha
- NAD kinase 2, mitochondrial
- NAD-dependent malic enzyme, mitochondrial
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
- NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
- NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- Probable D-lactate dehydrogenase, mitochondrial
- Propionyl-CoA carboxylase beta chain, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Serine hydroxymethyltransferase, mitochondrial
- Serine protease HTRA2, mitochondrial
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- Single-stranded DNA-binding protein, mitochondrial
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein uS2m
- Steroidogenic acute regulatory protein, mitochondrial
- Stress-70 protein, mitochondrial
- Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
- Succinyl-CoA
- Transcription factor A, mitochondrial
- Twinkle mtDNA helicase
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
- cAMP-dependent protein kinase catalytic subunit alpha
|
|
- A4
- AD1
- Aac2
- Acad8
- Acadsb
- Acat1
- Aco2
- Acot1
- Acot2
- Acot3
- Acot5
- Afg3l2
- Ahd-1
- Ahd1
- Alas1
- Aldh18a1
- Aldh1b1
- Aldh2
- Aldhx
- Ant2
- App
- Arg2
- Atp5a1
- Atp5b
- Atp5c1
- Atp5f1a
- Atp5f1b
- Atp5f1c
- Atp5h
- Atp5j
- Atp5l
- Atp5mg
- Atp5o
- Atp5pd
- Atp5pf
- Atp5po
- Atp6
- Atpase6
- Bdh
- Bdh1
- COI
- Clpp
- Clpx
- Cox5a
- Cox5b
- Cs
- Cte1
- D12Wsu28e
- Dbt
- Dci
- Dld
- Ech1
- Eci1
- Emre
- Erab
- Fech
- Fh
- Fh1
- Glud
- Glud1
- Grim19
- Grp75
- Hadh
- Hadh2
- Hadhsc
- Heg1
- Hmgcs2
- Hmgts
- Hsd17b10
- Hsp60
- Hsp74
- Hspa9
- Hspa9a
- Hspd1
- Htra2
- Iars2
- Idh2
- Idh3a
- Inpp5e
- Kiaa4192
- Ldhd
- Lonp1
- Mdh2
- Me2
- Mnadk
- Mor1
- Mrpl12
- Mrpl32
- Mrps10
- Mrps2
- Mschad
- Mtatp6
- Mtco1
- Mte1
- Nadk2
- Nadkd1
- Ndufa13
- Ndufa2
- Ndufs1
- Ndufs3
- Ndufv1
- Ndufv3
- Ogdh
- Omi
- Oxct
- Oxct1
- Oxsm
- P5cs
- Pccb
- Pdha-1
- Pdha1
- Pdhb
- Pdk1
- Peo1
- Pkaca
- Pmpca
- Prkaca
- Prss15
- Prss25
- Pte1a
- Pte2
- Pte2a
- Pycs
- Rpml12
- Schad
- Scot
- Shmt2
- Slc25a5
- Smdt1
- Spg7
- Ssbp1
- Star
- Suclg2
- Tfam
- Twnk
- Uqcrc2
- Uqcrq
- mt-Atp6
- mt-Co1
|
|
Thrombin signalling through proteinase activated receptors (PARs)
|
|
|
- Arrb1
- Arrb2
- Cf2
- Cf2r
- Erk1
- Erk2
- F2
- F2r
- F2rl2
- F2rl3
- Gna-11
- Gna-12
- Gna-13
- Gna-14
- Gna-15
- Gna11
- Gna12
- Gna13
- Gna14
- Gna15
- Gnaq
- Gnb1
- Gnb2
- Gnb3
- Gnb4
- Gnb5
- Gng1
- Gng10
- Gng11
- Gng12
- Gng13
- Gng2
- Gng3
- Gng4
- Gng5
- Gng7
- Gng8
- Gng9
- Gngt1
- Gngt11
- Gngt2
- Gngt3
- Gngt4
- Gngt5
- Gngt7
- Gngt8
- Gngt9
- Mapk
- Mapk1
- Mapk3
- Par1
- Par3
- Par4
- Prkm1
- Prkm3
- Src
|
|
Sema3A PAK dependent Axon repulsion
|
|
|
- Fes
- Fps
- Fyn
- Hsp84
- Hsp84-1
- Hsp86
- Hsp86-1
- Hsp90aa1
- Hsp90ab1
- Hspc3
- Hspca
- Hspcb
- Kiaa0463
- Kiaa1550
- Kiaa4053
- Limk
- Limk1
- Nrp
- Nrp1
- Pak-3
- Pak1
- Pak2
- Pak3
- Paka
- Pakb
- Plxna1
- Plxna2
- Plxna3
- Plxna4
- Rac1
- SemD
- Sema3a
- Semad
- Stk4
|
|
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
|
|
|
- Farp2
- Fyn
- Kiaa0463
- Kiaa0589
- Kiaa0793
- Kiaa1550
- Kiaa4053
- Nrp
- Nrp1
- Pip5k1c
- Plxna1
- Plxna2
- Plxna3
- Plxna4
- SemD
- Sema3a
- Semad
- Tln
- Tln1
|
|
Hyaluronan biosynthesis and export
|
|
|
- Abcc5
- Abcc5a
- Cemip
- Has
- Has1
- Has2
- Has3
- Hybid
- Kiaa1199
- Mrp5
|
|
EPH-ephrin mediated repulsion of cells
|
|
|
- Ad3h
- Ad4h
- Alg3
- Aph1a
- Aph1b
- Cekl
- Clg4b
- Efnb1
- Efnb2
- Efnb3
- Elf2
- Ephb1
- Ephb2
- Ephb3
- Ephb4
- Ephb6
- Epl2
- Epl5
- Eplg2
- Eplg5
- Epth3
- Etk2
- Fyn
- Htk
- Htkl
- Lerk2
- Lerk5
- Lyn
- Mdk2
- Mdk5
- Mmp2
- Mmp9
- Myk1
- Ncstn
- Nuk
- Pen2
- Ps-2
- Psen1
- Psen2
- Psenen
- Psnl1
- Psnl2
- Rac1
- Sek3
- Sek4
- Src
- Stra1
- Tiam-1
- Tiam1
- Vav2
- Vav3
- Yes
- Yes1
|
|
Ephrin signaling
|
|
|
- Arhgef7
- Cekl
- Efnb1
- Efnb2
- Efnb3
- Elf2
- Ephb1
- Ephb2
- Ephb3
- Ephb4
- Ephb6
- Epl2
- Epl5
- Eplg2
- Eplg5
- Epth3
- Etk2
- Fyn
- Git1
- Grb4
- Htk
- Htkl
- Kiaa0142
- Lerk2
- Lerk5
- Mdk2
- Mdk5
- Myk1
- Nck2
- Nuk
- Pak-3
- Pak1
- Pak2
- Pak3
- Pak3bp
- Paka
- Pakb
- Rac1
- Sdcbp
- Sek3
- Sek4
- Src
- Stk4
- Stra1
|
|
Alternative complement activation
|
|
|
- Adn
- Bf
- C3
- Cfb
- Cfd
- Df
- Gzmm
- H2-Bf
- LMet-1
- MMET-1
|
|
RHO GTPases activate PAKs
|
|
|
- Calm
- Calm1
- Cam
- Cam1
- Cdc42
- Fln
- Fln1
- Flna
- Limk
- Limk1
- Mrlc2
- Myh10
- Myh11
- Myh14
- Myh9
- Myl12b
- Myl6
- Myl9
- Mylc2b
- Mylk
- Myln
- Mypt1
- Mypt2
- Myrl2
- Nf-2
- Nf2
- Pak-3
- Pak1
- Pak2
- Pak3
- Paka
- Pakb
- Ppp1cb
- Ppp1r12a
- Ppp1r12b
- Rac1
- Stk4
|
|
Regulation of ornithine decarboxylase (ODC)
|
|
|
- Azin1
- Dia4
- Kiaa0072
- Kiaa0077
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Nmo1
- Nmor1
- Nqo1
- Oaz
- Oaz1
- Oaz2
- Oaz3
- Oazi
- Oazin
- Odc
- Odc1
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Ring12
- Sez15
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
|
|
Spry regulation of FGF signaling
|
|
|
- B-raf
- Braf
- Cbl
- Erk1
- Erk2
- Mapk
- Mapk1
- Mapk3
- Mknk1
- Mnk1
- Ppp2ca
- Ppp2cb
- Ppp2r1a
- Prkm1
- Prkm3
- Ptpn11
- Rps27a
- Spry2
- Src
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
LDL remodeling
|
|
|
|
|
GABA synthesis, release, reuptake and degradation
|
|
|
- Cplx1
- Cspalpha
- Dnajc5
- Gad1
- Gad2
- Gad65
- Gad67
- Hsc70
- Hsc73
- Hspa8
- Kiaa0340
- Rab3a
- Rab3ip1
- Rim1
- Rims1
- Slc32a1
- Snap
- Snap25
- Stx1a
- Stxbp1
- Syb2
- Syt1
- Vamp2
- Vgat
- Viaat
|
|
Negative regulation of the PI3K/AKT network
|
|
|
- Akt
- Akt1
- Akt2
- Akt3
- Ctmp
- Kiaa0606
- Mmac1
- Nipk
- Phlpp
- Phlpp1
- Phlpp2
- Phlppl
- Plekhe1
- Pten
- Rac
- Scop
- Them4
- Trb3
- Trib3
|
|