GlyCosmos Portal

Rattus norvegicus (Norway rat)

Summary

Taxonomy ID: 10116
PubChem Taxonomy: 10116

Genes (449) Glycans (773) Glycoproteins (2935) Lectins (166) Pathways (1070)

Displaying entries **951 - 975** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
NCAM signaling for neurite out-growth	Cyclic AMP-responsive element-binding protein 1 Focal adhesion kinase 1 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neural cell adhesion molecule 1 Receptor-type tyrosine-protein phosphatase alpha Ribosomal protein S6 kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 2 Spectrin beta chain Spectrin beta chain Spectrin beta chain Spectrin, alpha, erythrocytic 1 Spectrin, beta, non-erythrocytic 5 Tyrosine-protein kinase Fyn	A0A0G2JY25 A0A0G2K677 A0A8I6A7D1 A0A8I6AWM3 D4A3T0 D4A678 G3V6S0 O35346 P08644 P13596 P15337 P16086 P20171 P21708 P62994 P63086 Q03348 Q04970 Q62844 Q9QWN8	Ash Creb-1 Creb1 Erk1 Erk2 Fak Fak1 Fyn Grb2 Hras Hras1 Kras Kras2 Lrp Mapk Mapk1 Mapk3 Ncam Ncam1 Nras Prkm1 Prkm3 Ptk2 Ptpra Rps6ka5 Sos1 Spna2 Spnb3 Spta1 Spta2 Sptan1 Sptb Sptbn1 Sptbn2 Sptbn4 Sptbn5
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4	D3ZUM2 D3ZXR7 M0RA08 Q56DL5 Q63691 Q9QX05	Cd14 Ly96 Plin3 Sarm1 Ticam1 Ticam2 Tlr4
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Hypocretin neuropeptide precursor Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Orexigenic neuropeptide QRFP Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pro-FMRFamide-related neuropeptide FF Pyroglutamylated RFamide peptide receptor like	A0A8I6AD76 O55232 P56718 P56719 P83860 Q9EP86 Q9EQD2 Q9WVA9	Gpr147 Gpr74 Hcrt Hcrtr1 Hcrtr2 Npff Npff1 Npff2 Npffr1 Npffr2 Npgpr Ox P518 Ppox Qrfp Qrfprl RGD1560028
TRAF6-mediated induction of TAK1 complex within TLR4 complex	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 D3ZUM2 D3ZXR7 M0RA08 P0C8E4 P0CG51 P62982 Q4QQS0 Q56DL5 Q5U303 Q63429 Q63691 Q9QX05	Cd14 Irak2 LOC100360645 Ly96 Map3k7 Map3k7ip2 Plin3 Rps27a Sarm1 Tab1 Tab2 Tab3 Ticam1 Ticam2 Tlr4 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
Activation of NF-kappaB in B cells	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 B-cell lymphoma/leukemia 10 Beta-transducin repeat containing E3 ubiquitin protein ligase Caspase recruitment domain family, member 11 Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta MALT1 paracaspase NF-kappa-B essential modulator NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NFKB inhibitor epsilon Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein kinase C beta type RELA proto-oncogene, NF-kB subunit S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZMV7 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6AA96 A0A8I6AH74 A0A8I6ANR6 A0A8I6G2R1 A0A8I6GIW9 B0BN93 D4A980 F1LMQ3 F1LMZ8 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 P68403 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63746 Q63797 Q63798 Q6P780 Q6PEC4 Q6TMG5 Q9JHW0 Q9JIA3 Q9QY78 Q9QYN5 Q9WTV5 Q9Z2X3	Bcl10 Btrc Card11 Chuk Cul1 Fbxw11 Ikba Ikbb Ikbkb Ikbkg Ikkb LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Malt1 Mecl1 Mss1 Nemo Nfkbia Nfkbib Nfkbie Pkcb Prkcb Prkcb1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rela Ring12 Rps27a Skp1 Skp1a Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
VEGFR2 mediated vascular permeability	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Cadherin-5 Calmodulin-3 Catenin beta-1 Catenin delta 1 Caveolin-1 Heat shock protein HSP 90-alpha Junction plakoglobin Nitric oxide synthase 3 Proline-rich protein 5 Proto-oncogene vav RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase RPTOR independent companion of MTOR, complex 2 Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase mTOR Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3	A0A0G2JXM1 A0A0G2K0I6 A0A8I5ZNG4 A0A8I5ZPB5 D3ZYG0 O55173 P0DP31 P35465 P41350 P42346 P47196 P47197 P54100 P82995 Q566R0 Q5FVG6 Q62600 Q62829 Q63484 Q64303 Q6AYF1 Q6P0K8 Q6RUV5 Q9WTQ6 Q9WU82 Q9Z2K5	Akt1 Akt2 Akt3 CaMIII Calm3 Cam3 Camc Catnb Cav Cav1 Cdh5 Ctnnb1 Ctnnd1 Frap1 Gbl Hsp86 Hsp90aa1 Hspca Jup Lst8 Mapkap1 Mip1 Mlst8 Mtor Nipk Nos3 Pak1 Pak2 Pak3 Pdk1 Pdpk1 Pg Protor1 Prr5 Rac Rac1 Raft1 Rictor Sin1 Them4 Trib3 Vav Vav1 Vav2 Vav3
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	Protein DEK Transcription factor AP-2-alpha	P58197 Q6AXS3	Dek Tcfap2a Tfap2a
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Aurora kinase A Cullin 1 F-box and leucine-rich repeat protein 18 F-box and leucine-rich repeat protein 7 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Ring-box 1 S-phase kinase-associated protein 1 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A0G2KAX0 A0A8I5XVT7 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 B0BN93 F1LMQ3 F1LMZ8 F1M6I7 F1M6W6 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P59241 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Aik Airk1 Ark1 Aura Aurka Ayk1 Btak Cul1 Fbxl18 Fbxl18l1 Fbxl7 Iak1 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Rbx1 Ring12 Rps27a Skp1 Skp1a Stk15 Stk6 Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
MET activates PI3K/AKT signaling	GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	A0A0G2K344 D3ZAL7 P17945 P62994 P97523 Q63787	Ash Gab1 Grb2 Hgf Met Pik3ca Pik3r1
NADE modulates death signalling	14-3-3 protein epsilon Beta-nerve growth factor Caspase-2 Caspase-3 Protein BEX3 Tumor necrosis factor receptor superfamily member 16	P07174 P25427 P55213 P55215 P62260 Q6PDU5	Bex3 Casp2 Casp3 Cpp32 Ich1 Nade Ngf Ngfb Ngfr Ngfrap1 Tnfrsf16 Ywhae
Pyruvate metabolism	Alanine aminotransferase 1 Hydroxyacylglutathione hydrolase, mitochondrial L-lactate dehydrogenase A chain L-lactate dehydrogenase B chain L-lactate dehydrogenase C chain L-lactate dehydrogenase Lactoylglutathione lyase Malic enzyme Malic enzyme NADP-dependent malic enzyme Oxaloacetate decarboxylase, mitochondrial Pyruvate carboxylase, mitochondrial Pyruvate kinase PKLR Pyruvate kinase Voltage-dependent anion-selective channel protein 1	A0A0G2K502 F1M5N4 M0RD14 O35952 P04642 P12928 P13697 P19629 P25409 P42123 P52873 Q6AYQ8 Q6P7Q4 Q7TNA8 Q9Z2L0	Aat1 Fahd1 Glo1 Gpt Gpt1 Hagh LOC100362738 Ldh-1 Ldh-2 Ldh-3 Ldh1 Ldh2 Ldh3 Ldha Ldhal6b Ldhb Ldhc Me1 Me2 Me3 Mod-1 Mod1 Pc Pklr Pkml1 Rsp29 Vdac1
O-linked glycosylation	Dolichyl-phosphate-mannose--protein mannosyltransferase Dystroglycan 1 Hexosyltransferase LARGE xylosyl- and glucuronyltransferase 1 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Protein O-mannose kinase Protein O-mannosyl-transferase 1 Xylosyl- and glucuronyltransferase LARGE2	A0A0G2K618 D3Z9C4 F1M8K0 Q14U74 Q4V8A9 Q5NDF0 Q5XIN7 Q6P7A1 Q99PR0	Ago61 B3galnt2 Dag1 Gtdc2 Gyltl1b Large1 Large2 Pomgnt1 Pomgnt2 Pomk Pomt1 Pomt2 Sgk196
Processing of DNA double-strand break ends	ATR interacting protein BRCA1 interacting helicase 1 BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein homolog Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint control protein Checkpoint protein Claspin Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA 3'-5' helicase DNA 3'-5' helicase DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase II binding protein 1 DNA topoisomerase Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 HECT-type E3 ubiquitin transferase Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 Histone acetyltransferase KAT5 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin Nuclear receptor binding SET domain protein 2 Protein inhibitor of activated STAT, 4 Protein phosphatase 4, regulatory subunit 2 Protein timeless homolog RAD1 checkpoint DNA exonuclease RAD17 checkpoint clamp loader component RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ mediated genome instability 2 RecQ-mediated genome instability protein 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 32 kDa subunit Replication protein A subunit Replication protein A3 SUMO-conjugating enzyme UBC9 Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein phosphatase 4 catalytic subunit Small ubiquitin-related modifier 2 TIMELESS-interacting protein TIMELESS-interacting protein Tumor protein p53 binding protein 1 Ubiquitin-conjugating enzyme E2 variant 2	A0A0G2JUC9 A0A0G2JVY9 A0A0G2JXI9 A0A0G2K475 A0A0G2K4W8 A0A8I5ZSA8 A0A8I6A014 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6GFZ6 B1WC58 B2RYM5 B2RYR0 B4F778 B5DF29 B5DFF9 D3Z822 D3ZC52 D3ZG52 D3ZHC3 D3ZHX4 D3ZNA8 D3ZQW1 D3ZXM2 D3ZXP3 D4A4M3 D4A6J4 D4A845 D4A8H5 D4A9J4 D4ACL8 E9PTL1 F1LM96 F1LTH9 F1M842 G3V9C7 M0RBQ5 O54952 P61959 P62804 P63281 Q00729 Q499V3 Q4KLN8 Q4QR88 Q5BJ92 Q5I0F1 Q5M830 Q5PQK4 Q5U2M8 Q5XIJ6 Q63528 Q63699 Q641W4 Q6AY13 Q6AY26 Q6P7Q1 Q7M767 Q7TP21 Q91ZN7 Q99MK2 Q9JIL8 Q9JIL9 Q9JIM0 Q9QZH2 Q9Z2Y1	ABRAXAS1 Abra1 Atm Atr Atrip Babam1 Babam2 Bard1 Blm Brca1 Brcc3 Brcc36 Bre Brip1 Ccdc98 Ccna1 Ccna2 Cdk2 Cdkn2 Chek1 Chk1 Clspn Ctip Dna2 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Exo1 Fam175a H2afx H2ax H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Herc2 Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist4 Hist4h4 Htatip Hus1 Kat5 LOC100365043 LOC100910200 LOC120094818 LOC684797 Mdc1 Merit40 Mms2 Mre11 Mre11a Nba1 Nbn Nbs1 Nsd2 Pias4 Ppp4c Ppp4r2 RGD1564788 Rad1 Rad17 Rad50 Rad9a Rad9b Rap80 Rbbp8 Rfc2 Rfc3 Rfc4 Rfc5 Rhno1 Rmi1 Rmi2 Rnf168 Rnf8 Rpa1 Rpa2 Rpa3 Smt3a Smt3h2 Sumo2 Th2b Timeless Tip60 Tip60b Tipin Tipinl1 Top3a Topbp1 Tp53bp1 Ubce9 Ube2i Ube2v2 Uev2 Uimc1 Whsc1 Wrn
phospho-PLA2 pathway	Cytosolic phospholipase A2 Mitogen-activated protein kinase 1	P50393 P63086	Cpla2 Erk2 Mapk Mapk1 Pla2g4 Pla2g4a Prkm1
Platelet sensitization by LDL	Apolipoprotein B-100 Cytosolic phospholipase A2 LDL receptor related protein 8 Mitogen-activated protein kinase 14 Platelet endothelial cell adhesion molecule Protein phosphatase 2 scaffold subunit A alpha Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Tyrosine-protein kinase Fgr Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	A0A8I5ZMG6 A0A8I5ZRC2 A0A8I6A6K6 D3ZDI7 D3ZE75 P41499 P50393 P62716 P63331 P70618 P81718 Q3SWT0 Q4QQT4 Q5XI34 Q6P6U0 Q7TMA5 Q80W83	Apob Cpla2 Csbp1 Csbp2 Fgr LOC100909468 Lrp8 Mapk14 Pecam Pecam1 Pla2g4 Pla2g4a Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Ptph6 Ptpn11 Ptpn6
Regulation of CDH11 function	ADAM metallopeptidase domain 19 ADAM metallopeptidase domain 33 Angiomotin Angiopoietin-related protein 4 Cadherin 11 Catenin beta-1 Catenin delta 1 Junction plakoglobin	A0A0G2JX94 A0A0G2JXM1 A0A8I5ZUZ5 D3ZPM7 F1MAH6 Q6P0K8 Q6TMA8 Q9WU82	Adam19 Adam33 Amot Angptl4 Catnb Cdh11 Ctnnb1 Ctnnd1 Jup Pg
Glucagon signaling in metabolic regulation	Glucagon receptor Pro-glucagon	P06883 P30082	Gcg Gcgr
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Polyubiquitin-B Polyubiquitin-C Protein kinase C zeta type TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2K612 A0A8I6A4L9 A0A8I6A5Y3 P09217 P0CG51 P17246 P38438 P61589 P62982 P80204 Q63429 Q6B4M5 Q9JHY1 Q9Z340	Arha Arha2 Cgn F11r Jam1 LOC100360645 Par-6a Par3 Par6a Pard3 Pard6a Pkcz Prkcz Rhoa Rps27a Smurf1 Tgfb1 Tgfbr1 Tgfbr2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
SCF(Skp2)-mediated degradation of p27/p21	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin 1 Cyclin E2 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1A Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinases regulatory subunit G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta S-phase kinase associated protein 2 S-phase kinase-associated protein 1 Tyrosine-protein kinase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JVY9 A0A8I5Y0H0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZZ18 A0A8I6A5Y3 A0A8I6AMP0 B0BN93 B2RZ99 D3ZDS3 D3ZQ41 F1LMQ3 F1LMZ8 F7FGV7 G3V6W6 G3V8G2 O08769 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P35426 P39948 P39949 P40112 P40307 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63699 Q63797 Q63798 Q6AY13 Q6PEC4 Q9JHW0 Q9WTV5 Q9Z2X3	Ccna1 Ccna2 Ccnd1 Ccne Ccne1 Ccne2 Cdk2 Cdk4 Cdkn1a Cdkn1b Cdkn2 Cks1b Cks1l Cul1 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psmf1 Ptk6 RGD1561797 Ring12 Rps27a Skp1 Skp1a Skp2 Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 p27Kip1
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	ADP-ribosylation factor-like protein 2-binding protein ADP-ribosylation factor-like protein 2 ADP/ATP translocase 1 ADP/ATP translocase 2 Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 2 Equilibrative nucleoside transporter 3 Sodium/nucleoside cotransporter 1 Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3 Solute carrier family 29 member 4	F1M2Y4 O08697 O54698 O54699 Q05962 Q09073 Q4V8C5 Q62674 Q62773 Q80WK7 Q8VIH3	Aac1 Ant1 Ant2 Arl184 Arl2 Arl2bp Bart Bart1 Cnt1 Cnt2 Cnt3 Ent1 Ent2 Ent3 Slc25a4 Slc25a5 Slc28a1 Slc28a2 Slc28a3 Slc29a1 Slc29a2 Slc29a3 Slc29a4 Spnt
GRB2 events in EGFR signaling	Amphiregulin Betacellulin GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I6AQ55 D4A3T0 G3V6K6 P01134 P07522 P08644 P20171 P24338 P62994 Q04970 Q06175 Q9Z0L5	Areg Ash Btc Dtr Egf Egfr Ereg Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Nras Sdgf Sos1 Tgfa
Signaling by NODAL	Forkhead box O3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	D3ZBQ1 O70436 O70437 P21708 P63086 P84025	Erk1 Erk2 Foxo3 Madh2 Madh3 Madh4 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Smad2 Smad3 Smad4
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Crk-like protein Cytoplasmic protein Cytoplasmic protein GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B (Fragment) Proto-oncogene tyrosine-protein kinase Src Rap guanine nucleotide exchange factor 1 Ras GTPase-activating protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription Tyrosine-protein phosphatase non-receptor type 11	A0A0G2JX93 A0A0G2K2M3 A0A0G2K344 B2RZ33 D4A3M8 D4A3T0 F1M8L9 P08644 P10686 P20171 P20786 P28576 P41499 P50904 P52631 P52632 P62994 Q04970 Q05028 Q05030 Q5U2U2 Q62771 Q63767 Q63768 Q63787 Q63788 Q9QZC5 Q9WUD9 Q9Z1L0	Ash Bcar1 Cas Crk Crkas Crkl Crko Grb2 Grb7 Hras Hras1 Kras Kras2 Mgf Nck1 Nck2 Nras Pdgfa Pdgfb Pdgfr Pdgfr1 Pdgfra Pdgfrb Pik3ca Pik3cb Pik3r1 Pik3r2 Plcg1 Ptpn11 Rapgef1 Rasa Rasa1 Rpa1 Sos1 Src Stat1 Stat3 Stat4 Stat5a Stat5b Stat6
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7	P08909 P14842 P19327 P28564 P28565 P30940 P30994 P31388 P32305 P35364 Q62758	5ht1a 5ht1b 5ht1c 5ht1f 5ht5a Htr1a Htr1b Htr1c Htr1d Htr1f Htr2 Htr2a Htr2b Htr2c Htr4 Htr5a Htr6 Htr7 Srl
Retinoid metabolism and transport	Agrin Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member B8 Aldo-keto reductase family 1, member C1 Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Apolipoprotein M Beta,beta-carotene 15,15'-dioxygenase Carotenoid-cleaving dioxygenase, mitochondrial Colipase Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Glypican 4 Glypican 5 Glypican 6 Glypican-1 Glypican-2 Glypican-3 LDL receptor related protein 10 LDL receptor related protein 12 LDL receptor related protein 8 LRRGT00111 Lecithin retinol acyltransferase Lipoprotein lipase Low-density lipoprotein receptor-related protein 2 Pancreatic triacylglycerol lipase Phospholipase B1, membrane-associated Prolow-density lipoprotein receptor-related protein 1 Retinol-binding protein 1 Retinol-binding protein 2 Retinol-binding protein 4 Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Transthyretin	A0A8I6A609 A0A8I6ACQ6 A3KN98 D3ZCF7 D3ZE75 D3ZZL5 F7F3K1 G3V8D4 G3V928 O54728 P02650 P02651 P02696 P02767 P04638 P04639 P04916 P06759 P06768 P13265 P14630 P17084 P25304 P26260 P27657 P33671 P34900 P34901 P35053 P51653 P98158 Q06000 Q3MHS3 Q642B0 Q6AY99 Q6AYQ2 Q6TUD3 Q7TMA5 Q91XT5 Q9JI61	Agrin Agrn Akr1b10 Akr1c1 Akr1c21 Apoa1 Apoa2 Apoa4 Apob Apoc2 Apoc3 Apoe Apom Bcdo Bcdo1 Bcmo1 Bco1 Bco2 Clps Crbpii Gpc1 Gpc2 Gpc3 Gpc4 Gpc5 Gpc6 Gpihbp1 Hsd17b5 Hspg1 Lpl Lrat Lrp1 Lrp10 Lrp12 Lrp2 Lrp8 Phlpb Plb1 Pnlip Rbp-1 Rbp1 Rbp2 Rbp4 Rdh11 Sdc1 Sdc2 Sdc3 Sdc4 Synd1 Synd2 Synd3 Synd4 Tt Ttr

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