GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **701 - 725** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Carboxyterminal post-translational modifications of tubulin	Cytosolic carboxypeptidase 1 Cytosolic carboxypeptidase 2 Cytosolic carboxypeptidase 3 Cytosolic carboxypeptidase 4 Cytosolic carboxypeptidase 6 Cytosolic carboxypeptidase-like protein 5 Inactive polyglycylase TTLL10 Leucine-rich repeat-containing protein 49 Nicolin-1 Polyglutamylase complex subunit TTLL1 Probable tubulin polyglutamylase TTLL2 Probable tubulin polyglutamylase TTLL9 Protein monoglycylase TTLL8 Small vasohibin-binding protein Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-3E chain Tubulin beta 8B Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain Tubulin beta-8 chain Tubulin monoglutamylase TTLL4 Tubulin monoglycylase TTLL3 Tubulin polyglutamylase TTLL11 Tubulin polyglutamylase TTLL13 Tubulin polyglutamylase TTLL5 Tubulin polyglutamylase TTLL6 Tubulin polyglutamylase TTLL7 Tubulin polyglutamylase complex subunit 1 Tubulin polyglutamylase complex subunit 2 Tubulin--tyrosine ligase-like protein 12 Tubulin--tyrosine ligase Tubulinyl-Tyr carboxypeptidase 1 Tubulinyl-Tyr carboxypeptidase 2	A6NNM8 A6NNZ2 A6PVC2 O95922 P04350 P0DPH7 P0DPH8 P68363 P68371 Q13509 Q13885 Q14166 Q14679 Q3SXZ7 Q3ZCM7 Q5U5Z8 Q5VU57 Q68CL5 Q6EMB2 Q6PEY2 Q6ZT98 Q6ZTW0 Q6ZVT0 Q71U36 Q7L8A9 Q86V25 Q8IUZ0 Q8N300 Q8N841 Q8NDL9 Q8NEM8 Q8NG68 Q8NHH1 Q96MI9 Q9BQE3 Q9BSH3 Q9BUF5 Q9BVA1 Q9BWV7 Q9H4B7 Q9UPW5 Q9Y4R7	AGBL1 AGBL2 AGBL3 AGBL4 AGBL5 AGTPBP1 C18orf10 C19orf20 C20orf125 C22orf7 C6orf104 C9orf20 CCDC23 CCP1 CCP2 CCP3 CCP4 CCP5 CCP6 CSTPP2 KIAA0153 KIAA0173 KIAA0998 KIAA1035 KIAA1036 LRRC49 NICN1 NNA1 STAMP SVBP TPGS1 TPGS2 TTL TTL.6 TTLL1 TTLL10 TTLL11 TTLL12 TTLL13 TTLL13P TTLL2 TTLL3 TTLL4 TTLL5 TTLL6 TTLL7 TTLL8 TTLL9 TUBA1A TUBA1B TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA3E TUBA6 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6 TUBB8 TUBB8B VASH VASH1 VASH2 VASHL	Homo sapiens (human)
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	Bifunctional polynucleotide phosphatase/kinase DNA ligase 3 DNA polymerase beta DNA repair protein XRCC1 Endonuclease 8-like 1 Endonuclease 8-like 2 N-glycosylase/DNA lyase	O15527 P06746 P18887 P49916 Q969S2 Q96FI4 Q96T60	LIG3 MMH MUTM NEIL1 NEIL2 OGG1 OGH1 PNKP POLB XRCC1	Homo sapiens (human)
Negative regulation of activity of TFAP2 (AP-2) family transcription factors	BTB/POZ domain-containing protein KCTD15 BTB/POZ domain-containing protein KCTD1 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor AP-2-delta Transcription factor AP-2-epsilon WW domain-containing oxidoreductase	P05549 P63165 P63279 Q6VUC0 Q719H9 Q7Z6R9 Q92481 Q92754 Q96SI1 Q9NZC7	AP2TF C18orf5 FOR KCTD1 KCTD15 SDR41C1 SMT3C SMT3H3 SUMO1 TFAP2 TFAP2A TFAP2B TFAP2BL1 TFAP2C TFAP2D TFAP2E UBC9 UBCE9 UBE2I UBL1 WOX1 WWOX	Homo sapiens (human)
RHOQ GTPase cycle	ADP-ribosylation factor-like protein 13B ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Actin nucleation-promoting factor WASL Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 2 Cdc42 effector protein 3 Cdc42 effector protein 4 Cdc42-interacting protein 4 Cell division control protein 42 homolog Copine-8 Cystic fibrosis transmembrane conductance regulator DEP domain-containing protein 1B Formin-binding protein 1 Gap junction alpha-1 protein Glucose-fructose oxidoreductase domain-containing protein 1 Golgi-associated PDZ and coiled-coil motif-containing protein Intersectin-1 Junction plakoglobin MAGUK p55 subfamily member 7 Metalloreductase STEAP3 NEDD4-like E3 ubiquitin-protein ligase WWP2 Neutral amino acid transporter B(0) Obscurin Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Pleckstrin homology domain-containing family G member 3 Protein diaphanous homolog 3 Protein scribble homolog Ragulator complex protein LAMTOR1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP3 Ras-related protein Rab-7a Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 33 Rho GTPase-activating protein 35 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho-related GTP-binding protein RhoQ SLIT-ROBO Rho GTPase-activating protein 2 Serine/threonine-protein kinase MRCK alpha Serine/threonine-protein kinase MRCK beta Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Sodium bicarbonate cotransporter 3 Stomatin Synaptosomal-associated protein 23 Transferrin receptor protein 1 Vang-like protein 1 Vesicle-associated membrane protein 3	A1L390 A7KAX9 O00161 O00308 O00401 O14559 O14613 O43307 O60890 O75044 O96013 P02786 P13569 P14923 P17081 P17302 P27105 P46940 P51149 P60953 Q00587 Q03135 Q07960 Q13017 Q13153 Q13177 Q14155 Q14160 Q14161 Q15642 Q15758 Q15811 Q15836 Q3SXY8 Q5T2T1 Q5T5U3 Q5VST9 Q5VT25 Q658P3 Q68EM7 Q6IAA8 Q6ZW31 Q86VI3 Q86YQ8 Q8TAA9 Q8TCU6 Q8WUY9 Q96QB1 Q96RU3 Q9H3Q1 Q9HD26 Q9NRY4 Q9NSV4 Q9NXC2 Q9UKI2 Q9UNA1 Q9Y2X7 Q9Y5S2 Q9Y6M7	ABCC7 ARHDH9 ARHGAP1 ARHGAP10 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP33 ARHGAP34 ARHGAP35 ARHGAP5 ARHGAP7 ARHGEF7 ARHGEF9 ARHQ ARL13B ARL2L1 ASCT2 BND7 BORG1 BORG2 BORG4 BORG5 BT C11orf59 C6orf114 CAL CAV CAV1 CDC42 CDC42BPA CDC42BPB CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42GAP CEP1 CEP2 CEP3 CEP4 CFTR CIP4 COOL1 CPNE8 CRIB1 CTNNG DEPDC1B DIAP3 DIAPH3 DLC1 DP3 EPB72 FBP17 FIG FNBP1 FNBP2 GFOD1 GIT1 GIT2 GJA1 GJAL GOPC GRAF GRF1 GRIT GRLF1 IQGAP1 IQGAP3 ITSN ITSN1 JUP KIAA0051 KIAA0142 KIAA0147 KIAA0148 KIAA0424 KIAA0451 KIAA0456 KIAA0554 KIAA0599 KIAA0621 KIAA0712 KIAA1124 KIAA1142 KIAA1415 KIAA1424 KIAA1556 KIAA1639 KIAA1722 KIAA1723 LAMTOR1 LAP4 M7V1 MPP7 MSE55 NBC2 NBC2B NBC3 NBCn1 OBSCN OPHN1 OPHN1L P190A P85SPR PAK1 PAK2 PAK3BP PAK4 PDRO PIXB PLEKHG3 PREX1 RAB7 RAB7A RASL7A RDR RDRC RHOGAP1 RHOGAP5 RHOQ RICH1 RICS SBC2 SCRB1 SCRIB SH3D1A SLC1A5 SLC4A6 SLC4A7 SNAP23 SNX26 SRGAP2 SRGAP2A STARD12 STB2 STEAP3 STOM STOT STP SYB3 SYDE1 TC10 TCGAP TFRC TRIP10 TSAP6 VAMP3 VANGL1 VARTUL WASL WWP2 XTP8 p190ARHOGAP	Homo sapiens (human)
Signaling by ERBB2 ECD mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Erbin GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1	P00533 P01111 P01112 P01133 P04626 P07900 P19174 P27986 P29353 P42336 Q07889 Q13480 Q16543 Q96RT1	CDC37 CDC37A EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN GAB1 GRB1 HER1 HER2 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL NRAS PIK3CA PIK3R1 PLC1 PLCG1 SHC SHC1 SHCA SOS1	Homo sapiens (human)
NS1 Mediated Effects on Host Pathways	Aladin E3 SUMO-protein ligase RanBP2 Importin subunit alpha-1 Importin subunit alpha-3 Importin subunit alpha-4 Importin subunit alpha-5 Importin subunit alpha-6 Importin subunit alpha-8 Importin subunit beta-1 Non-structural protein 1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog Ubiquitin-like protein ISG15 mRNA export factor RAE1	A8CG34 A9QM74 O00505 O00629 O15131 O15504 O75694 P03496 P05161 P12270 P35658 P37198 P49790 P49792 P52292 P52294 P55735 P57740 P78406 Q12769 Q14974 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E G1P2 ISG15 KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KPNA1 KPNA2 KPNA3 KPNA4 KPNA5 KPNA7 KPNB1 MP44 MRNP41 NDC1 NPAP60L NS NTF97 NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C QIP1 QIP2 RAE1 RANBP2 RCH1 RCH2 SEC13 SEC13A SEC13L1 SEC13R SRP1 TMEM48 TPR UCRP	Homo sapiens (human)
Defective C1GALT1C1 causes TNPS	C1GALT1-specific chaperone 1 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1	P15941 P98088 Q02505 Q02817 Q5SSG8 Q685J3 Q6W4X9 Q7Z5P9 Q8N307 Q8N387 Q8TAX7 Q8WXI7 Q96DR8 Q96EU7 Q99102 Q9H195 Q9H3R2 Q9HC84 Q9NS00 Q9UKN1	C1GALT1 C1GALT1C1 C6orf205 CA125 COSMC DRCC1 KIAA1359 MG2 MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 PUM RECC SBEM SMUC	Homo sapiens (human)
Folding of actin by CCT/TriC	Actin, cytoplasmic 1 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta-2 T-complex protein 1 subunit zeta	P17987 P40227 P48643 P49368 P50990 P50991 P60709 P78371 Q92526 Q99832	99D8.1 ACTB C21orf112 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT6A CCT6B CCT7 CCT8 CCTA CCTB CCTD CCTE CCTG CCTH CCTQ CCTZ KIAA0002 KIAA0098 NIP7-1 SRB TCP1 TRIC5	Homo sapiens (human)
Activation of caspases through apoptosome-mediated cleavage	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS IAP3 KIAA0413 MCH3 MCH6 XIAP	Homo sapiens (human)
Adherens junctions interactions	Angiogenin Cadherin-10 Cadherin-11 Cadherin-12 Cadherin-13 Cadherin-15 Cadherin-17 Cadherin-18 Cadherin-1 Cadherin-24 Cadherin-2 Cadherin-3 Cadherin-4 Cadherin-5 Cadherin-6 Cadherin-7 Cadherin-8 Cadherin-9 Catenin alpha-1 Catenin beta-1 Catenin delta-1 Cell adhesion molecule 1 Cell adhesion molecule 2 Cell adhesion molecule 3 Junction plakoglobin Nectin-1 Nectin-2 Nectin-3 Nectin-4	O60716 P03950 P12830 P14923 P19022 P22223 P33151 P35221 P35222 P55283 P55285 P55286 P55287 P55289 P55290 P55291 Q12864 Q13634 Q15223 Q86UP0 Q8N126 Q8N3J6 Q92692 Q96NY8 Q9BY67 Q9NQS3 Q9ULB4 Q9ULB5 Q9Y6N8	ANG CADM1 CADM2 CADM3 CDH1 CDH10 CDH11 CDH11L CDH12 CDH13 CDH14 CDH15 CDH17 CDH18 CDH2 CDH24 CDH3 CDH4 CDH5 CDH6 CDH7 CDH7L1 CDH8 CDH9 CDHE CDHH CDHN CDHP CTNNA1 CTNNB CTNNB1 CTNND1 CTNNG DP3 HVEB HVEC IGSF4 IGSF4A IGSF4B IGSF4D JUP KIAA0384 LNIR NCAD NECL1 NECL2 NECL3 NECTIN1 NECTIN2 NECTIN3 NECTIN4 PRR1 PRR2 PRR3 PRR4 PVRL1 PVRL2 PVRL3 PVRL4 RNASE5 SYNCAM SYNCAM3 TSLC1 TSLL1 UVO	Homo sapiens (human)
Serine biosynthesis	D-3-phosphoglycerate dehydrogenase Phosphoserine aminotransferase Phosphoserine phosphatase Serine incorporator 1 Serine incorporator 2 Serine incorporator 3 Serine incorporator 4 Serine incorporator 5 Serine racemase	A6NH21 O43175 P78330 Q13530 Q86VE9 Q96SA4 Q9GZT4 Q9NRX5 Q9Y617	C5orf12 DIFF33 KIAA1253 PGDH3 PHGDH PSA PSAT1 PSPH SERINC1 SERINC2 SERINC3 SERINC4 SERINC5 SRR TDE1 TDE1L TDE2 TDE2L	Homo sapiens (human)
Prevention of phagosomal-lysosomal fusion	Coronin-1A Dihydrolipoyl dehydrogenase ESAT-6-like protein EsxG ESAT-6-like protein EsxH Hepatocyte growth factor-regulated tyrosine kinase substrate Lipoarabinomannan carrier protein LprG Low molecular weight protein-tyrosine phosphatase A Nucleoside diphosphate kinase Phosphatidylinositol-3-phosphatase Polyubiquitin-B Polyubiquitin-C Protein translocase subunit SecA 2 Ras-related protein Rab-5A Ras-related protein Rab-7a Triacylglyceride transporter Rv1410c Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vacuolar protein sorting-associated protein 33B	O14964 O53361 O53692 P0CG47 P0CG48 P20339 P31146 P51149 P62979 P62987 P9WGP3 P9WHH9 P9WIA1 P9WJH7 P9WJY3 P9WK45 P9WNK3 Q9H267	CORO1 CORO1A HGS HRS RAB5 RAB5A RAB7 RAB7A RPS27A Rv1410c UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VPS33B cfp7 esxG esxH lpd lpdC lpp-27 lprG mptpA ndk ndkA ptpA sapM secA2	Homo sapiens (human)
rRNA modification in the mitochondrion	5-methylcytosine rRNA methyltransferase NSUN4 Dimethyladenosine transferase 1, mitochondrial Transcription termination factor 4, mitochondrial rRNA methyltransferase 1, mitochondrial rRNA methyltransferase 2, mitochondrial rRNA methyltransferase 3, mitochondrial	Q6IN84 Q7Z6M4 Q8WVM0 Q96CB9 Q9HC36 Q9UI43	FJH1 FTSJ2 MRM1 MRM2 MRM3 MTERF4 MTERFD2 NSUN4 RNMTL1 TFB1M	Homo sapiens (human)
Post-transcriptional silencing by small RNAs	Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	Q8NDV7 Q9H9G7 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 CAGH26 EIF2C1 EIF2C2 EIF2C3 EIF2C4 KIAA1093 KIAA1460 KIAA1567 KIAA1582 TNRC6 TNRC6A TNRC6B TNRC6C	Homo sapiens (human)
Ephrin signaling	ARF GTPase-activating protein GIT1 Cytoplasmic protein NCK2 Ephrin type-B receptor 1 Ephrin type-B receptor 2 Ephrin type-B receptor 3 Ephrin type-B receptor 4 Ephrin type-B receptor 6 Ephrin-B1 Ephrin-B2 Ephrin-B3 Myosin regulatory light chain 12A Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor 7 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Syntenin-1 Tyrosine-protein kinase Fyn	O00560 O15197 O43639 O75914 P06241 P19105 P29323 P52799 P54753 P54760 P54762 P63000 P98172 Q13153 Q13177 Q14155 Q15768 Q9Y2X7	ARHGEF7 COOL1 DRT EFL3 EFNB1 EFNB2 EFNB3 ELK EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPHT2 EPHT3 EPLG2 EPLG5 EPLG8 EPTH3 ERK ETK2 FYN GIT1 GRB4 HEK2 HEK5 HEK6 HTK HTKL KIAA0142 LERK2 LERK5 LERK8 MDA9 MLCB MRLC3 MYK1 MYL12A NCK2 NET OPHN3 P85SPR PAK1 PAK2 PAK3 PAK3BP PIXB RAC1 RLC SDCBP SYCL TC25 TYRO11 TYRO5 TYRO6	Homo sapiens (human)
Neurofascin interactions	Ankyrin-1 Contactin-1 Contactin-associated protein 1 Neurofascin Neuronal cell adhesion molecule Neuronal migration protein doublecortin Syntenin-1	O00560 O43602 O94856 P16157 P78357 Q12860 Q92823	ANK ANK1 CASPR CNTN1 CNTNAP1 DBCN DCX KIAA0343 KIAA0756 LISX MDA9 NFASC NRCAM NRXN4 SDCBP SYCL	Homo sapiens (human)
Molybdenum cofactor biosynthesis	Adenylyltransferase and sulfurtransferase MOCS3 Gephyrin Molybdenum cofactor sulfurase Molybdopterin synthase catalytic subunit Molybdopterin synthase sulfur carrier subunit	O95396 O96007 O96033 Q96EN8 Q9NQX3	GPH GPHN KIAA1385 MCBPE MOCO1 MOCOS MOCS2 MOCS3 UBA4	Homo sapiens (human)
Signaling by Insulin receptor	Insulin receptor Insulin	P01308 P06213	INS INSR	Homo sapiens (human)
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations	Death domain-associated protein 6 Transcriptional regulator ATRX	P46100 Q9UER7	ATRX BING2 DAP6 DAXX RAD54L XH2	Homo sapiens (human)
SHC-mediated cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 GTPase HRas GTPase NRas Son of sevenless homolog 1	O15520 O43320 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P21781 P31371 Q07889 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 NRAS SOS1	Homo sapiens (human)
FasL/ CD95L signaling	Caspase-10 Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 6	P25445 P48023 Q13158 Q14790 Q92851	APT1 APT1LG1 CASP10 CASP8 CD95L FADD FAS FAS1 FASL FASLG MCH4 MCH5 MORT1 TNFRSF6 TNFSF6	Homo sapiens (human)
RNA Polymerase II Pre-transcription Events	AF4/FMR2 family member 4 CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 ELL-associated factor 1 ELL-associated factor 2 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIE subunit 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Parafibromin Protein AF-9 Protein ENL Protein IWS1 homolog RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase II-associated factor 1 homolog RNA polymerase-associated protein CTR9 homolog RNA polymerase-associated protein LEO1 RNA polymerase-associated protein RTF1 homolog Superkiller complex protein 8 TATA-binding protein-associated factor 2N TATA-box-binding protein Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription elongation factor SPT6 Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 1-like Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 3 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7-like Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B	O00267 O00268 O15514 O60563 O60583 O75909 P13984 P18074 P18615 P19387 P19388 P19447 P20226 P21675 P23193 P24928 P29083 P29084 P30876 P32780 P35269 P36954 P42568 P49848 P50613 P50750 P51946 P51948 P52298 P52434 P52435 P52655 P52657 P53803 P55199 P61218 P62487 P62875 P63272 Q00403 Q03111 Q08945 Q09161 Q12962 Q13888 Q13889 Q14241 Q15369 Q15370 Q15542 Q15543 Q15544 Q15545 Q16514 Q16594 Q5H9L4 Q5VWG9 Q6P1J9 Q6P1X5 Q6PD62 Q6ZYL4 Q7KZ85 Q8IXH7 Q8IYF1 Q8IZX4 Q8N7H5 Q8WVC0 Q8WX92 Q92541 Q92750 Q92759 Q92804 Q96CJ1 Q96JC9 Q96ST2 Q9GZS3 Q9H3P2 Q9HBM6 Q9UHB7 Q9Y5B0 Q9Y5B9	AF5Q31 AF9 AFF4 BA2R BTF2 BTF2P44 C19orf17 C1orf28 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCG1 CCGS CCNH CCNK CCNT1 CCNT2 CDC2L4 CDC73 CDK7 CDK9 CDKN7 CIF150 COBRA1 CPR4 CTDP1 CTR9 EAF1 EAF2 ELL ELOA ELOA2 ELOB ELOC ENL ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2A1 GTF2A2 GTF2B GTF2D1 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HRPT2 IWS1 IWS1L KIAA0155 KIAA0162 KIAA0252 KIAA1182 LEO1 LTG19 MAT1 MCEF MLLT1 MLLT3 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE PAF1 PD2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RBP56 RD RDBP RDL RNF66 RPB7 RTF1 SH2BP1 SKIC8 SPT4H SPT5 SPT5H SPT6H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H SUPT6H TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF2A TAF2B TAF2C TAF2C1 TAF2C2 TAF2D TAF2E TAF2F TAF2G TAF2H TAF2I TAF2J TAF2K TAF2N TAF2Q TAF3 TAF4 TAF4A TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TAF9L TAFII105 TAFII130 TAFII135 TAFII18 TAFII20 TAFII30 TAFII31 TAFII55 TAFII70 TAK TBP TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TF2A1 TF2A2 TF2B TF2D TF2E1 TF2E2 TFIIB TFIID TFIIS TH1 TH1L TRAITS TTDA WDR61 WHSC2 XPB XPBC XPD XPDC YEATS1 YEATS3	Homo sapiens (human)
Acyl chain remodeling of CL	85/88 kDa calcium-independent phospholipase A2 Cytosolic phospholipase A2 Lysocardiolipin acyltransferase 1 Tafazzin Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	O60733 P40939 P47712 P55084 Q16635 Q6UWP7	AGPAT8 ALCAT1 CPLA2 EFE2 G4.5 HADH HADHA HADHB LCLAT1 LYCAT PLA2G4 PLA2G4A PLA2G6 PLPLA9 TAFAZZIN TAZ	Homo sapiens (human)
Inhibition of DNA recombination at telomere	Adrenocortical dysplasia protein homolog DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Death domain-associated protein 6 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H3.3 Histone H4 Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2 Transcriptional regulator ATRX	O15514 O60814 P04908 P06899 P0C5Y9 P16104 P19387 P19388 P20671 P23527 P24928 P30876 P33778 P36954 P46100 P52434 P52435 P53803 P54274 P57053 P58876 P61218 P62487 P62805 P62807 P62875 P84243 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q93077 Q93079 Q96A08 Q96AP0 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0 Q9UER7	ACD ATRX BING2 DAP6 DAXX DRIP5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3-4 H3.3A H3.3B H3F3 H3F3A H3F3B H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 PIN2 PIP1 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF POT1 PTOP RAD54L RAP1 RPB7 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B XH2	Homo sapiens (human)
Vasopressin regulates renal water homeostasis via Aquaporins	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Rab11 family-interacting protein 2 Ras-related protein Rab-11A Unconventional myosin-Vb Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14610 O14775 O43306 O60262 O60266 O60503 O95622 P01185 P10644 P13861 P16520 P17612 P22612 P22694 P29972 P30518 P31321 P31323 P40145 P41181 P50150 P50151 P51828 P55087 P59768 P61952 P62491 P62873 P62879 P63092 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q7L804 Q8NFM4 Q92482 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9ULV0	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADHR AQP1 AQP2 AQP3 AQP4 ARVP AVP AVPR2 CHIP28 DIR DIR3 GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA0941 KIAA1060 KIAA1119 MYO5B PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B RAB11 RAB11A RAB11FIP2 TSE1 V2R VP	Homo sapiens (human)

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