GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **876 - 900** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Dual Incision in GG-NER	Chromodomain-helicase-DNA-binding protein 1-like Cullin-4A Cullin-4B DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase kappa DNA repair endonuclease XPF DNA repair protein complementing XP-A cells E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P07992 P09874 P0CG47 P0CG48 P12004 P15927 P18074 P19447 P23025 P27694 P28340 P28715 P32780 P35244 P35249 P35250 P35251 P40937 P40938 P49005 P56282 P62877 P62979 P62987 Q07864 Q13619 Q13620 Q13888 Q13889 Q15054 Q16531 Q6ZYL4 Q86WJ1 Q92466 Q92759 Q92889 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9UGN5	ADPRT ADPRT2 ADPRTL2 ALC1 BTF2 BTF2P44 C6orf175 CHD1L CHRAC17 CUL4A CUL4B DDB1 DDB2 DINB1 DPE2 ERCC1 ERCC11 ERCC2 ERCC3 ERCC4 ERCC5 ERCM2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0039 KIAA0695 PARP1 PARP2 PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLK PPOL RBX1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 XAP1 XPA XPAC XPB XPBC XPD XPDC XPF XPG XPGC	Homo sapiens (human)
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	Cyclin-dependent kinase 2 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Retinoblastoma-associated protein	O96020 P06400 P24864 P24941	CCNE CCNE1 CCNE2 CDK2 CDKN2 RB1	Homo sapiens (human)
Formation of annular gap junctions	AP-2 complex subunit mu Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Disabled homolog 2 Dynamin-1 Dynamin-2 Gap junction alpha-1 protein	P09496 P09497 P17302 P50570 P53675 P98082 Q00610 Q05193 Q96CW1	AP2M1 CLAPM1 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD DAB2 DNM DNM1 DNM2 DOC2 DYN2 GJA1 GJAL KIAA0034 KIAA0109	Homo sapiens (human)
Eukaryotic Translation Elongation	Elongation factor 1-alpha 1 Elongation factor 1-alpha 2 Elongation factor 1-beta Elongation factor 1-delta Elongation factor 1-gamma Putative elongation factor 1-alpha-like 3	P24534 P26641 P29692 P68104 Q05639 Q5VTE0	EEF1A EEF1A1 EEF1A1P5 EEF1A2 EEF1AL EEF1AL3 EEF1B EEF1B2 EEF1D EEF1G EF1A EF1B EF1D EF1G LENG7 STN	Homo sapiens (human)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	15-hydroxyprostaglandin dehydrogenase [NAD(+)] 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Aldo-keto reductase family 1 member C3 Carbonyl reductase [NADPH] 1 Hematopoietic prostaglandin D synthase Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase 3 Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin reductase 2 Prostaglandin-H2 D-isomerase Prostamide/prostaglandin F synthase Thromboxane-A synthase	O14684 O60760 P15428 P16152 P23219 P24557 P35354 P41222 P42330 Q15185 Q16647 Q8N8N7 Q8TBF2 Q9H7Z7 Q9UNU6	AKR1C3 C1orf93 C9orf15 CBR CBR1 COX1 COX2 CRN CYP12 CYP5 CYP5A1 CYP8 CYP8A1 CYP8B1 DDH1 FAM213B GSTS HPGD HPGDS HSD17B5 KIAA0119 MGST1L1 MPGES1 P23 PDS PGDH1 PGDS PGES PGES2 PGFS PIG12 PRXL2B PTGDS PTGDS2 PTGES PTGES2 PTGES3 PTGIS PTGR2 PTGS1 PTGS2 SDR21C1 SDR36C1 TBXAS1 TEBP TXAS ZADH1	Homo sapiens (human)
RHO GTPases Activate WASPs and WAVEs	Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 BAR/IMD domain-containing adapter protein 2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Focal adhesion kinase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NCK-interacting protein with SH3 domain Nck-associated protein 1-like Nck-associated protein 1 Protein BRICK1 Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BTK WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A6NGB9 O00401 O15143 O15144 O15145 O15511 O43516 P00519 P16333 P27361 P28482 P42768 P55160 P59998 P60709 P60953 P61158 P61160 P63000 P63261 Q05397 Q06187 Q7L576 Q8IZP0 Q8TF74 Q8WUW1 Q92558 Q92747 Q96F07 Q9NYB9 Q9NZQ3 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y6W5	ABI1 ABI2 ABL ABL1 ACTB ACTG ACTG1 ACTR2 ACTR3 AF3P21 AGMX1 ARC16 ARC20 ARC21 ARC34 ARC41 ARGBPIA ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ATK BAIAP2 BPK BRK1 BTK C3orf10 CDC42 CR16 CYFIP1 CYFIP2 ERK1 ERK2 FAK FAK1 HEM1 HEM2 IMD2 JTK7 KIAA0068 KIAA0269 KIAA0587 KIAA0900 KIAA1168 MAPK1 MAPK3 NAP1 NCK NCK1 NCKAP1 NCKAP1L NCKIPSD PIR121 PRKM1 PRKM2 PRKM3 PTK2 RAC1 SCAR1 SCAR3 SOP2L SPIN90 SSH3BP1 TC25 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE	Homo sapiens (human)
RHO GTPases activate IQGAPs	CAP-Gly domain-containing linker protein 1 Cadherin-1 Calmodulin-1 Catenin alpha-1 Catenin beta-1 Cell division control protein 42 homolog Menin Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP2 Ras GTPase-activating-like protein IQGAP3 Ras-related C3 botulinum toxin substrate 1	O00255 P0DP23 P12830 P30622 P35221 P35222 P46940 P60953 P63000 Q13576 Q86VI3	CALM CALM1 CAM CAM1 CDC42 CDH1 CDHE CLIP1 CTNNA1 CTNNB CTNNB1 CYLN1 IQGAP1 IQGAP2 IQGAP3 KIAA0051 MEN1 RAC1 RSN SCG2 TC25 UVO	Homo sapiens (human)
Activation, translocation and oligomerization of BAX	Apoptosis regulator BAX BH3-interacting domain death agonist	P55957 Q07812	BAX BCL2L4 BID	Homo sapiens (human)
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate	Isocitrate dehydrogenase [NADP] cytoplasmic	O75874	IDH1 PICD	Homo sapiens (human)
Ion influx/efflux at host-pathogen interface	Copper transport protein ATOX1 Copper-transporting ATPase 1 Natural resistance-associated macrophage protein 1 PDZ domain-containing protein 11	O00244 P49279 Q04656 Q5EBL8	AIPP1 ATOX1 ATP7A HAH1 LSH MC1 MNK NRAMP NRAMP1 PDZD11 PDZK11 PISP SLC11A1	Homo sapiens (human)
NFE2L2 regulating MDR associated enzymes	ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family F member 2 Broad substrate specificity ATP-binding cassette transporter ABCG2 CREB-binding protein Histone acetyltransferase p300 Multidrug resistance-associated protein 1 Nuclear factor erythroid 2-related factor 2 Transcription factor MafK	O15438 O60675 P33527 Q09472 Q16236 Q92793 Q9UG63 Q9UNQ0	ABCC1 ABCC3 ABCF2 ABCG2 ABCP BCRP BCRP1 CBP CMOAT2 CREBBP EP300 MAFK MLP2 MRP MRP1 MRP3 MXR NFE2L2 NRF2 P300	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of other transcription factors	Cbp/p300-interacting transactivator 2 Pituitary homeobox 2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P05549 Q92754 Q99697 Q99967	AP2TF ARP1 CITED2 MRG1 PITX2 RGS RIEG RIEG1 TFAP2 TFAP2A TFAP2C	Homo sapiens (human)
RAC3 GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Abl interactor 1 Abl interactor 2 Actin remodeling regulator NHS Actin-binding protein WASF1 Actin-binding protein WASF2 Active breakpoint cluster region-related protein Amphoterin-induced protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 BAR/IMD domain-containing adapter protein 2-like 1 BAR/IMD domain-containing adapter protein 2 Breakpoint cluster region protein Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein 1 DEP domain-containing protein 1B Dedicator of cytokinesis protein 10 Delta(14)-sterol reductase LBR Desmoglein-2 Emerin Ephrin type-A receptor 2 Erbin Extended synaptotagmin-1 Fermitin family homolog 2 Granule associated Rac and RHOG effector protein 1 Guanine nucleotide exchange factor VAV2 Inner nuclear membrane protein Man1 Inositol polyphosphate 5-phosphatase OCRL Integrin beta-1 Interleukin-32 Lamina-associated polypeptide 2, isoforms beta/gamma MAGUK p55 subfamily member 7 Membrane-associated progesterone receptor component 2 NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase activator 1 NADPH oxidase organizer 1 Nck-associated protein 1-like Nck-associated protein 1 Neutral amino acid transporter B(0) Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Protein BRICK1 Protein ERGIC-53 Protein diaphanous homolog 3 Protein jagged-1 Proto-oncogene DBL Rac GTPase-activating protein 1 Ragulator complex protein LAMTOR1 Rap guanine nucleotide exchange factor 1 Ras-related C3 botulinum toxin substrate 3 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 2 Rho GTPase-activating protein 15 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 42 Rho GTPase-activating protein 5 Rho GTPase-activating protein 6 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor TIAM1 SLIT and NTRK-like protein 3 SLIT and NTRK-like protein 5 SLIT-ROBO Rho GTPase-activating protein 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase TAO3 Serine/threonine-protein kinase VRK2 Starch-binding domain-containing protein 1 Switch-associated protein 70 Synaptobrevin homolog YKT6 Synaptosomal-associated protein 23 Transferrin receptor protein 1 Triple functional domain protein Tyrosine-protein kinase ABL2 Vang-like protein 1 Vesicle-associated membrane protein 3	A6NI28 A7KAX9 O00161 O00459 O15063 O15173 O15498 O43182 O60890 O75044 O75962 O94933 O94991 O95210 O96013 P02786 P04839 P05556 P10911 P11274 P13498 P14598 P19878 P24001 P27986 P29317 P42167 P42684 P43121 P49257 P50402 P51149 P52566 P52735 P55160 P60763 P60953 P78504 Q00587 Q01968 Q03135 Q07960 Q12979 Q13009 Q13017 Q13153 Q13177 Q13905 Q14126 Q14161 Q14739 Q15080 Q15758 Q15836 Q53QZ3 Q5T2T1 Q5T5U3 Q68EM7 Q6IAA8 Q6T4R5 Q6ZW31 Q7L576 Q86SJ2 Q86UR1 Q86Y07 Q8IZP0 Q8NFA2 Q8TAA9 Q8TCU6 Q8WUW1 Q8WUY9 Q8WWN8 Q8WZ64 Q92558 Q96AC1 Q96BY6 Q96RT1 Q9BSJ8 Q9C0H5 Q9H0H5 Q9H2K8 Q9HBY0 Q9NRY4 Q9NSV4 Q9NYB9 Q9UH65 Q9UHR4 Q9UNA1 Q9UQB8 Q9Y2A7 Q9Y2U8 Q9Y2X7 Q9Y5S8 Q9Y6W5	ABI1 ABI2 ABL2 ABLL ABR ALI1 AMIGO2 ARAP2 ARAP3 ARG ARGBPIA ARHGAP1 ARHGAP10 ARHGAP15 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP34 ARHGAP35 ARHGAP39 ARHGAP42 ARHGAP5 ARHGAP6 ARHGDIB ASCT2 BAIAP2 BAIAP2L1 BCR BCR1 BORG5 BRK1 C11orf59 C3orf10 CAV CAV1 CDC42 CDC42EP1 CDC42GAP CDHF5 CENTD1 CENTD3 CEP1 CYBA CYBB CYFIP1 D22S11 DBL DEPDC1B DG6 DIAP3 DIAPH3 DOCK10 DPK DSG2 ECK EDMD EMD EPHA2 ERBB2IP ERBIN ERGIC53 ESYT1 F5F8D FAM62A FERMT2 FNBP2 FNRB GARRE1 GDIA2 GDID4 GIT1 GIT2 GRAF GRAF3 GRB1 GRF1 GRF2 GRIT GRLF1 HEM1 HEM2 IL32 IRTKS ITGB1 JAG1 JAGL1 JIK KDS KIAA0068 KIAA0148 KIAA0269 KIAA0355 KIAA0456 KIAA0580 KIAA0587 KIAA0621 KIAA0640 KIAA0694 KIAA0712 KIAA0747 KIAA0848 KIAA0918 KIAA1142 KIAA1225 KIAA1415 KIAA1424 KIAA1478 KIAA1688 KIAA1722 KIND2 LAMTOR1 LAP2 LBR LEMD3 LMAN1 LRRC11 M7V1 MAN1 MAP3K18 MBC2 MCAM MCF2 MDF2 MGCRACGAP MIG2 MOX1 MOX2 MPP7 MSE55 MSK12 MUC18 NAP1 NCF1 NCF2 NCF4 NCKAP1 NCKAP1L NHS NK4 NOH1 NOX1 NOX2 NOX3 NOXA1 NOXA2 NOXO1 NOXO2 OCRL OCRL1 OPHN1 OPHN1L P190A P41NOX P51NOX P67PHOX PAK1 PAK2 PAK4 PDRO PGRMC2 PIK3R1 PIK3R2 PLEKHC1 PMBP PREX1 RAB7 RAB7A RAC3 RACGAP1 RAP1GN1 RAPGEF1 RDR RDRC RHOGAP1 RHOGAP5 RHOGAP6 RICH1 RICS SCAR1 SH3PXD1A SH3PXD4 SH3PXD5 SLC1A5 SLITRK3 SLITRK5 SNAP23 SRGAP2 SRGAP2A SSH3BP1 STA STB2 STBD1 SWAP70 SYB3 SYDE1 TAIF TAOK3 TFRC TIAM1 TMEM133 TMPO TRIO VAMP3 VANGL1 VAV2 VRK2 WASF1 WASF2 WAVE1 WAVE2 XTP8 YKT6 ZIZ3 p190ARHOGAP	Homo sapiens (human)
Defective SFTPA2 causes IPF	Pulmonary surfactant-associated protein A2	Q8IWL1	COLEC5 PSAP SFTP1 SFTPA SFTPA2 SFTPA2B	Homo sapiens (human)
Golgi Associated Vesicle Biogenesis	ADP-ribosylation factor 1 AP-1 complex subunit beta-1 AP-1 complex subunit gamma-1 AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-1 complex subunit sigma-3 AP-3 complex subunit beta-1 AP-3 complex subunit sigma-1 AP-4 complex subunit beta-1 AP-4 complex subunit epsilon-1 Adaptin ear-binding coat-associated protein 1 Alpha-soluble NSF attachment protein Auxilin Beta-arrestin-1 Biogenesis of lysosome-related organelles complex 1 subunit 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Biogenesis of lysosome-related organelles complex 1 subunit 4 Biogenesis of lysosome-related organelles complex 1 subunit 6 Carboxypeptidase D Cation-independent mannose-6-phosphate receptor Clathrin interactor 1 Cyclin-G-associated kinase Dynamin-2 Dysbindin Endophilin-A1 Ferritin heavy chain Ferritin light chain Golgi resident protein GCP60 Golgin subfamily B member 1 Heat shock cognate 71 kDa protein Huntingtin-interacting protein 1-related protein Inositol polyphosphate 5-phosphatase OCRL Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol-binding clathrin assembly protein Protein YIPF6 Pumilio homolog 1 Ras-related protein Rab-5C SH3 domain-containing protein 19 SNARE-associated protein Snapin Sortilin Sorting nexin-2 Sorting nexin-5 Sorting nexin-9 TBC1 domain family member 8B Thioredoxin domain-containing protein 5 Trans-Golgi network integral membrane protein 2 Transferrin receptor protein 1 Tumor protein D52 Tumor protein D53 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8	O00203 O00443 O14976 O43493 O43747 O60749 O75061 O75146 O75976 O95295 P02786 P02792 P02794 P11142 P11717 P49407 P50570 P51148 P51809 P54920 P55327 P56377 P61966 P63027 P78537 P84077 Q01968 Q0IIM8 Q10567 Q13492 Q14671 Q14677 Q14789 Q16890 Q5HYK7 Q6QNY0 Q8NBS9 Q8NC96 Q92572 Q96EC8 Q96EV8 Q96PC3 Q99523 Q99962 Q9BV40 Q9BXS5 Q9H3P7 Q9NUP1 Q9UL45 Q9UPM8 Q9Y5X1 Q9Y5X3 Q9Y6B7 Q9Y6Q5	ACBD3 ADTB1 ADTB3A ADTG AP19 AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP3B1 AP3S1 AP4B1 AP4E1 ARF1 ARR1 ARRB1 BAM22 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S6 BLOC1S7 BLOC1S8 BLOS1 BLOS3 CALM CLAPB2 CLAPG1 CLAPS1 CLAPS3 CLINT1 CLTNM CNO CNSA2 CPD DNAJC26 DNAJC6 DNM2 DTNBP1 DYN2 ENTH EPN4 EPNR FTH FTH1 FTHL6 FTL GAK GCN5L1 GCP60 GOCAP1 GOLGB1 GOLPH1 HIP12 HIP1R HSC70 HSP73 HSPA10 HSPA8 IGF2R KIAA0099 KIAA0171 KIAA0473 KIAA0655 MPRI NAPA NECAP1 OCRL OCRL1 PA PICALM PIK3C2A PLDN PUM1 PUMH1 RAB5C RABL RT14 SH3D19 SH3D2A SH3GL2 SH3PX1 SH3PXD3A SNAP25BP SNAPA SNAPAP SNAPIN SNX2 SNX5 SNX9 SORT1 SYB2 SYBL1 TBC1D8B TFRC TGN46 TGN51 TGOLN2 TLP46 TPD52 TPD52L1 TXNDC5 VAMP2 VAMP7 VAMP8 YIPF6	Homo sapiens (human)
RNA Polymerase II Transcription Initiation And Promoter Clearance	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIE subunit 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 TATA-binding protein-associated factor 2N TATA-box-binding protein Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 1-like Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 3 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7-like Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B	O00268 O15514 P13984 P18074 P19387 P19388 P19447 P20226 P21675 P24928 P29083 P29084 P30876 P32780 P35269 P36954 P49848 P50613 P51946 P51948 P52434 P52435 P52655 P52657 P53803 P61218 P62487 P62875 Q00403 Q12962 Q13888 Q13889 Q15542 Q15543 Q15544 Q15545 Q16514 Q16594 Q5H9L4 Q5VWG9 Q6P1X5 Q6ZYL4 Q8IZX4 Q92750 Q92759 Q92804 Q9HBM6	BA2R BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCG1 CCGS CCNH CDK7 CDKN7 CIF150 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2D1 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MAT1 MNAT1 MO15 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RBP56 RNF66 RPB7 STK1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF2A TAF2B TAF2C TAF2C1 TAF2C2 TAF2D TAF2E TAF2F TAF2G TAF2H TAF2I TAF2J TAF2K TAF2N TAF2Q TAF3 TAF4 TAF4A TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TAF9L TAFII105 TAFII130 TAFII135 TAFII18 TAFII20 TAFII30 TAFII31 TAFII55 TAFII70 TBP TF2A1 TF2A2 TF2B TF2D TF2E1 TF2E2 TFIIB TFIID TTDA XPB XPBC XPD XPDC	Homo sapiens (human)
Vitamin B1 (thiamin) metabolism	Mitochondrial thiamine pyrophosphate carrier Thiamine pyrophosphokinase 1 Thiamine transporter 1 Thiamine transporter 2 Thiamine-triphosphatase	O60779 Q9BU02 Q9BZV2 Q9H3S4 Q9HC21	DNC MUP1 SLC19A2 SLC19A3 SLC25A19 THT1 THTPA TPK1 TRMA	Homo sapiens (human)
Translation of Replicase and Assembly of the Replication Transcription Complex	Beclin-1 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Microtubule-associated proteins 1A/1B light chain 3B ORF8b protein ORF9b protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphoinositide 3-kinase regulatory subunit 4 Replicase polyprotein 1a Replicase polyprotein 1ab UV radiation resistance-associated gene protein	O43633 P0C6U8 P0C6X7 P59636 Q14457 Q80H93 Q8NEB9 Q8WUX9 Q96CF2 Q96FZ7 Q99570 Q9BY43 Q9GZQ8 Q9H444 Q9P2Y5 Q9UQN3 Q9Y3E7	1a 8b 9b BC2 BECN1 C14orf123 C20orf178 CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 GT197 MAP1ALC3 MAP1LC3B NEDF PIK3C3 PIK3R4 SHAX1 SHAX2 SHAX3 UVRAG VPS15 VPS20 VPS24 VPS34 rep	Homo sapiens (human)
ZBP1(DAI) mediated induction of type I IFNs	Z-DNA-binding protein 1	Q9H171	C20orf183 DLM1 ZBP1	Homo sapiens (human)
mTORC1-mediated signalling	14-3-3 protein beta/alpha Eukaryotic elongation factor 2 kinase Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E-binding protein 1 Eukaryotic translation initiation factor 4E GTP-binding protein Rheb Neutral amino acid transporter 9 Peptidyl-prolyl cis-trans isomerase FKBP1A Proline-rich AKT1 substrate 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Ribosomal protein S6 kinase beta-1 Serine/threonine-protein kinase mTOR Small ribosomal subunit protein eS6 Target of rapamycin complex subunit LST8	O00418 O43504 P06730 P23443 P23588 P31946 P42345 P62753 P62942 Q04637 Q0VGL1 Q13541 Q15382 Q5VZM2 Q6IAA8 Q7L523 Q8N122 Q8NBW4 Q96B36 Q9BVC4 Q9HB90 Q9NQL2 Q9UHA4 Q9Y2Q5	AKT1S1 C11orf59 C7orf59 EEF2K EIF4B EIF4E EIF4EBP1 EIF4EL1 EIF4F EIF4G EIF4G1 EIF4GI FKBP1 FKBP12 FKBP1A FRAP FRAP1 FRAP2 GBL HBXIP KIAA1303 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MTOR PDRO PRAS40 RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPS6 RPS6KB1 RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 STK14A URLC11 XIP YWHAB	Homo sapiens (human)
RNA Polymerase III Abortive And Retractive Initiation	DNA-directed RNA polymerase III subunit RPC10 DNA-directed RNA polymerase III subunit RPC1 DNA-directed RNA polymerase III subunit RPC2 DNA-directed RNA polymerase III subunit RPC3 DNA-directed RNA polymerase III subunit RPC4 DNA-directed RNA polymerase III subunit RPC5 DNA-directed RNA polymerase III subunit RPC6 DNA-directed RNA polymerase III subunit RPC7-like DNA-directed RNA polymerase III subunit RPC7 DNA-directed RNA polymerase III subunit RPC8 DNA-directed RNA polymerase III subunit RPC9 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor 3C polypeptide 1 General transcription factor 3C polypeptide 2 General transcription factor 3C polypeptide 3 General transcription factor 3C polypeptide 4 General transcription factor 3C polypeptide 5 General transcription factor 3C polypeptide 6 Lupus La protein Nuclear factor 1 A-type Nuclear factor 1 B-type Nuclear factor 1 C-type Nuclear factor 1 X-type POU domain, class 2, transcription factor 1 Protein POLR1D, isoform 2 TATA-box-binding protein Transcription factor IIIA Transcription factor IIIB 50 kDa subunit Transcription factor IIIB 90 kDa subunit Transcription factor TFIIIB component B'' homolog Zinc finger protein 143 snRNA-activating protein complex subunit 1 snRNA-activating protein complex subunit 2 snRNA-activating protein complex subunit 3 snRNA-activating protein complex subunit 4 snRNA-activating protein complex subunit 5	A6H8Y1 O00712 O14802 O15160 O15318 O75575 O75971 P05423 P05455 P08651 P0DPB5 P14859 P19388 P20226 P52434 P52747 P53803 P61218 P62875 Q12789 Q12857 Q13487 Q14938 Q16533 Q5SXM2 Q8WUA4 Q92664 Q92966 Q92994 Q969F1 Q9BT43 Q9BUI4 Q9H1D9 Q9HAW0 Q9NVU0 Q9NW08 Q9UKN8 Q9Y2Y1 Q9Y535 Q9Y5Q8 Q9Y5Q9	BDP1 BN51 BN51T BRF BRF1 BRF2 BRFU C6orf51 CRCP GTF2D1 GTF3A GTF3B GTF3C1 GTF3C2 GTF3C3 GTF3C4 GTF3C5 GTF3C6 KIAA0011 KIAA1241 KIAA1439 KIAA1452 KIAA1665 KIAA1689 NFI NFIA NFIB NFIC NFIX OCT1 OTF1 POLR1C POLR1D POLR1E POLR2E POLR2F POLR2H POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3E POLR3F POLR3G POLR3GL POLR3H POLR3K POLRF POU2F1 RPC11 RPC8 SBF SNAP19 SNAP190 SNAP43 SNAP45 SNAP50 SNAPC1 SNAPC2 SNAPC3 SNAPC4 SNAPC5 SSB STAF TAF3B2 TAF3C TBP TF2D TFIID TFNR ZNF143	Homo sapiens (human)
Defective cofactor function of FVIIIa variant	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
A tetrasaccharide linker sequence is required for GAG synthesis	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Beta-1,3-galactosyltransferase 6 Beta-1,4-galactosyltransferase 7 Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Neurocan core protein Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Versican core protein Xylosyltransferase 1 Xylosyltransferase 2	O00468 O14594 O75056 O75487 O94766 O95196 P07585 P13611 P18827 P21810 P31431 P34741 P35052 P51654 P78333 P98160 Q6UVK1 Q86Y38 Q8N158 Q96GW7 Q96L58 Q9H1B5 Q9NPZ5 Q9P2W7 Q9UBV7 Q9Y625	AGRIN AGRN B3GALT6 B3GAT1 B3GAT2 B3GAT3 B4GALT7 BCAN BEHAB BGN CALEB CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 DCN GLCATP GLCATS GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HSPG1 HSPG2 KIAA0468 KIAA1963 MCSP NCAN NEUR NGC OCI5 SDC SDC1 SDC2 SDC3 SDC4 SLRR1A SLRR1B VCAN XGALT1 XT1 XT2 XYLT1 XYLT2	Homo sapiens (human)
Defensins	Beta-defensin (Fragment) Beta-defensin 103 Beta-defensin 104 Beta-defensin 105 Beta-defensin 106 Beta-defensin 107 Beta-defensin 108B Beta-defensin 110 Beta-defensin 112 Beta-defensin 113 Beta-defensin 114 Beta-defensin 115 Beta-defensin 116 Beta-defensin 119 Beta-defensin 121 Beta-defensin 123 Beta-defensin 124 Beta-defensin 125 Beta-defensin 126 Beta-defensin 127 Beta-defensin 128 Beta-defensin 129 Beta-defensin 130A Beta-defensin 130B Beta-defensin 131A Beta-defensin 132 Beta-defensin 133 Beta-defensin 134 Beta-defensin 135 Beta-defensin 1 Defensin alpha 4 Defensin alpha 5 Defensin beta 118 Defensin beta 136 Defensin beta 4A Defensin-6 Neutrophil defensin 1 Neutrophil defensin 3	O15263 P0DP73 P0DP74 P12838 P59665 P59666 P59861 P60022 P81534 Q01523 Q01524 Q30KP8 Q30KP9 Q30KQ1 Q30KQ3 Q30KQ4 Q30KQ5 Q30KQ6 Q30KQ7 Q30KQ8 Q30KQ9 Q4QY38 Q5J5C9 Q7Z7B7 Q7Z7B8 Q8IZN7 Q8N104 Q8N687 Q8N688 Q8N690 Q8NES8 Q8NET1 Q8NG35 Q8WTQ1 Q96PH6 Q9BYW3 Q9H1M3 Q9H1M4	BD1 BD3 BD5 BD6 C20orf63 C20orf73 C20orf8 C20orf87 DEF1 DEF3 DEF4 DEF5 DEF6 DEFA1 DEFA1B DEFA2 DEFA3 DEFA4 DEFA5 DEFA6 DEFB1 DEFB10 DEFB102 DEFB103 DEFB103A DEFB103B DEFB104 DEFB104A DEFB104B DEFB105 DEFB105A DEFB105B DEFB106 DEFB106A DEFB106B DEFB107 DEFB107A DEFB107B DEFB108 DEFB108B DEFB11 DEFB110 DEFB111 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB117 DEFB118 DEFB119 DEFB12 DEFB120 DEFB121 DEFB123 DEFB124 DEFB125 DEFB126 DEFB127 DEFB128 DEFB129 DEFB13 DEFB130 DEFB130A DEFB130B DEFB131 DEFB131A DEFB132 DEFB133 DEFB134 DEFB135 DEFB136 DEFB14 DEFB15 DEFB16 DEFB18 DEFB19 DEFB2 DEFB20 DEFB21 DEFB23 DEFB24 DEFB25 DEFB26 DEFB27 DEFB28 DEFB29 DEFB3 DEFB30 DEFB31 DEFB32 DEFB4 DEFB4A DEFB4B DEFB5 DEFB6 DEFB7 DEFB8 ESC42 HBD1 MRS	Homo sapiens (human)
Interleukin-9 signaling	Cytokine receptor common subunit gamma Interleukin-9 receptor Interleukin-9 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3	P15248 P23458 P31785 P40763 P42224 P42229 P51692 P52333 Q01113	APRF IL2RG IL9 IL9R JAK1 JAK1A JAK1B JAK3 STAT1 STAT3 STAT5 STAT5A STAT5B	Homo sapiens (human)

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