GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1226 - 1250** of **2074** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
cell division	Kinesin-like protein KIF20A Kinesin-like protein KIF23 Serine/threonine-protein kinase PLK1	O95235 P53350 Q02241	KIF20A KIF23 KNSL5 MKLP1 MKLP2 PLK PLK1 RAB6KIFL	Homo sapiens (human)
Synthesis of PIPs at the ER membrane	Myotubularin-related protein 5 Phosphatidylinositol 4-kinase alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2 Phosphatidylinositol-3-phosphatase SAC1	O95248 P42356 Q13614 Q8TCG2 Q9NTJ5	KIAA0851 KIAA1073 MTMR2 MTMR5 PI4K2B PI4KA PIK4 PIK4CA SAC1 SACM1L SBF1	Homo sapiens (human)
Defective ABCC6 causes PXE	ATP-binding cassette sub-family C member 6	O95255	ABCC6 ARA MRP6	Homo sapiens (human)
Interleukin-18 signaling	Interleukin-13 Interleukin-18 receptor 1 Interleukin-18 receptor accessory protein Interleukin-18-binding protein Interleukin-18 Interleukin-37 Interleukin-4 Polyunsaturated fatty acid 5-lipoxygenase	O95256 O95998 P05112 P09917 P35225 Q13478 Q14116 Q9NZH6	ALOX5 FIL1Z IGIF IL13 IL18 IL18BP IL18R1 IL18RAP IL1F4 IL1F7 IL1H4 IL1R7 IL1RP1 IL1RRP IL37 IL4 LOG5 NC30	Homo sapiens (human)
The fatty acid cycling model	Brain mitochondrial carrier protein 1 Dicarboxylate carrier SLC25A8 Mitochondrial brown fat uncoupling protein 1 Mitochondrial uncoupling protein 4 Putative mitochondrial transporter UCP3	O95258 O95847 P25874 P55851 P55916	BMCP1 SLC25A14 SLC25A27 SLC25A7 SLC25A8 SLC25A9 UCP UCP1 UCP2 UCP3 UCP4 UCP5	Homo sapiens (human)
Rap1 signalling	14-3-3 protein beta/alpha 14-3-3 protein zeta/delta RAF proto-oncogene serine/threonine-protein kinase RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Rap1 GTPase-activating protein 1 Rap1 GTPase-activating protein 2 Ras-related protein Rap-1A Ras-related protein Rap-1b Signal-induced proliferation-associated protein 1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O95267 O95398 P04049 P17612 P22612 P22694 P31946 P47736 P61224 P62834 P63104 Q684P5 Q7LDG7 Q8WZA2 Q96FS4	CDC25L CGEF1 CGEF2 EPAC EPAC1 EPAC2 GARNL4 KIAA0474 KIAA1039 KREV1 MCG7 PKACA PRKACA PRKACB PRKACG RAF RAF1 RAP1A RAP1B RAP1GA1 RAP1GA2 RAP1GAP RAP1GAP2 RAPGEF3 RAPGEF4 RASGRP RASGRP1 RASGRP2 SIPA1 SPA1 YWHAB YWHAZ	Homo sapiens (human)
Activation of RAS in B cells	GTPase HRas GTPase NRas RAS guanyl-releasing protein 1 Ras guanyl-releasing protein 3	O95267 P01111 P01112 Q8IV61	GRP3 HRAS HRAS1 KIAA0846 NRAS RASGRP RASGRP1 RASGRP3	Homo sapiens (human)
XAV939 stabilizes AXIN	Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2	O95271 Q9H2K2	PARP5A PARP5B PARPL TANK2 TIN1 TINF1 TNKL TNKS TNKS1 TNKS2	Homo sapiens (human)
Myoclonic epilepsy of Lafora	E3 ubiquitin-protein ligase NHLRC1 Glycogen [starch] synthase, muscle Glycogenin-1 Laforin Polyubiquitin-B Polyubiquitin-C Protein phosphatase 1 regulatory subunit 3C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O95278 P0CG47 P0CG48 P13807 P46976 P62979 P62987 Q6VVB1 Q9UQK1	EPM2A EPM2B GYG GYG1 GYS GYS1 NHLRC1 PPP1R3C PPP1R5 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Deoxyribose-phosphate aldolase Glucose-6-phosphate 1-dehydrogenase Phosphopentomutase Ribokinase Ribose-5-phosphate isomerase Ribulose-phosphate 3-epimerase-like protein 1 Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase	O95336 P11413 P29401 P37837 P49247 P52209 Q2QD12 Q96AT9 Q96G03 Q9H477 Q9UHJ6 Q9Y315	CARKL DERA G6PD PGD PGDH PGLS PGM2 RBKS RBSK RPE RPEL1 RPI RPIA SHPK TAL TALDO TALDO1 TALDOR TKT	Homo sapiens (human)	G31080DL
Defective ABCB11 causes PFIC2 and BRIC2	Bile salt export pump	O95342	ABCB11 BSEP	Homo sapiens (human)
Mitochondrial tRNA aminoacylation	Alanine--tRNA ligase, mitochondrial Asparaginyl-tRNA synthetase Aspartate--tRNA ligase, mitochondrial Glutamine--tRNA ligase Glycine--tRNA ligase Histidine--tRNA ligase, mitochondrial Inorganic pyrophosphatase 2, mitochondrial Isoleucine--tRNA ligase, mitochondrial Leucine--tRNA ligase, mitochondrial Lysine--tRNA ligase Methionine--tRNA ligase, mitochondrial Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial Phenylalanine--tRNA ligase, mitochondrial Probable arginine--tRNA ligase, mitochondrial Probable cysteine--tRNA ligase, mitochondrial Probable proline--tRNA ligase, mitochondrial Serine--tRNA ligase, mitochondrial Threonine--tRNA ligase, mitochondrial Tryptophan--tRNA ligase, mitochondrial Tyrosine--tRNA ligase, mitochondrial Valine--tRNA ligase, mitochondrial	O95363 P41250 P47897 P49590 Q15031 Q15046 Q5JPH6 Q5JTZ9 Q5ST30 Q5T160 Q6PI48 Q7L3T8 Q96GW9 Q96I59 Q9BW92 Q9H2U2 Q9HA77 Q9NP81 Q9NSE4 Q9UGM6 Q9Y2Z4	AARS2 AARSL CARS2 DARS2 EARS2 FARS1 FARS2 GARS GARS1 HARS2 HARSL HARSR HO3 IARS2 KARS KARS1 KIAA0028 KIAA0070 KIAA1270 KIAA1885 KIAA1970 LARS2 MARS2 NARS2 PARS2 PPA2 QARS QARS1 RARS2 RARSL SARS2 SARSM TARS2 TARSL1 VARS2 VARS2L VARSL WARS2 YARS2	Homo sapiens (human)
PI Metabolism	Tumor necrosis factor alpha-induced protein 8-like protein 1 Tumor necrosis factor alpha-induced protein 8-like protein 2 Tumor necrosis factor alpha-induced protein 8-like protein 3 Tumor necrosis factor alpha-induced protein 8	O95379 Q5GJ75 Q6P589 Q8WVP5	TIPE3 TNFAIP8 TNFAIP8L1 TNFAIP8L2 TNFAIP8L3	Homo sapiens (human)
Molecules associated with elastic fibres	Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein 4 Bone morphogenetic protein 7 EGF-containing fibulin-like extracellular matrix protein 1 EGF-containing fibulin-like extracellular matrix protein 2 Fibulin-1 Fibulin-2 Fibulin-5 Growth/differentiation factor 5 Integrin alpha-8 Integrin alpha-V Integrin beta-1 Integrin beta-3 Integrin beta-5 Integrin beta-6 Integrin beta-8 Latent-transforming growth factor beta-binding protein 1 Latent-transforming growth factor beta-binding protein 2 Latent-transforming growth factor beta-binding protein 3 Latent-transforming growth factor beta-binding protein 4 Microfibril-associated glycoprotein 3 Microfibril-associated glycoprotein 4 Microfibrillar-associated protein 2 Microfibrillar-associated protein 5 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein Vitronectin	O95393 O95967 P01137 P04004 P05106 P05556 P06756 P10600 P12643 P12644 P18075 P18084 P18564 P23142 P26012 P43026 P53708 P55001 P55082 P55083 P61812 P98095 Q12805 Q13361 Q14766 Q14767 Q8N2S1 Q9NS15 Q9UBX5	BMP10 BMP14 BMP2 BMP2A BMP2B BMP4 BMP7 C14orf141 CDMP1 DANCE DVR4 EFEMP1 EFEMP2 FBLN1 FBLN2 FBLN3 FBLN4 FBLN5 FBNL FNRB GDF5 GP3A ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP2 LTBP3 LTBP4 MAGP1 MAGP2 MDF2 MFAP2 MFAP3 MFAP4 MFAP5 MSK12 MSK8 OP1 TGFB TGFB1 TGFB2 TGFB3 VNRA VTN VTNR	Homo sapiens (human)
Molybdenum cofactor biosynthesis	Adenylyltransferase and sulfurtransferase MOCS3 Gephyrin Molybdenum cofactor sulfurase Molybdopterin synthase catalytic subunit Molybdopterin synthase sulfur carrier subunit	O95396 O96007 O96033 Q96EN8 Q9NQX3	GPH GPHN KIAA1385 MCBPE MOCO1 MOCOS MOCS2 MOCS3 UBA4	Homo sapiens (human)
TNF signaling	BAG family molecular chaperone regulator 4 Disintegrin and metalloproteinase domain-containing protein 17 Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor	O95429 P01375 P19438 P78536 Q12933 Q13546 Q15628	ADAM17 BAG4 CSVP RIP RIP1 RIPK1 SODD TACE TNF TNFA TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF2 TRAP3	Homo sapiens (human)
Surfactant metabolism	Adenosine deaminase 2 Adenosine receptor A2a Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Cytokine receptor common subunit beta Cytoskeleton-associated protein 4 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha LIM and cysteine-rich domains protein 1 Napsin-A P2Y purinoceptor 2 Palmitoyltransferase ZDHHC2 Pepsin A-3 Pepsin A-4 Pepsin A-5 Phospholipid-transporting ATPase ABCA3 Pro-cathepsin H Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Scavenger receptor cysteine-rich domain-containing protein DMBT1 Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Surfactant-associated protein 3 Thyroid transcription factor 1-associated protein 26 Transcription factor GATA-6 Transcription termination factor 1	O95436 O96009 P07988 P08913 P09668 P0C7M3 P0DJD7 P0DJD8 P0DJD9 P11686 P15509 P18825 P29274 P29275 P32927 P35247 P41231 Q06495 Q07065 Q15361 Q8IWL1 Q8IWL2 Q8IZF2 Q92908 Q99758 Q9NZK5 Q9NZU5 Q9P031 Q9UGM3 Q9UIJ5	ABC3 ABCA3 ADA2 ADGF ADGRF5 ADORA2 ADORA2A ADORA2B ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR BR22 CCDC59 CECR1 CKAP4 COLEC4 COLEC5 COLEC7 CPSB CSF2R CSF2RA CSF2RB CSF2RY CTSH DMBT1 GATA6 GP340 GPR116 IDGFL IL3RB IL5RB KIAA0758 LMCD1 NAP1 NAPA NAPSA NPT2 P2RU1 P2RY2 PGA3 PGA4 PGA5 PSAP PSPD REAM REC SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH SLC17A2 SLC34A1 SLC34A2 TAP26 TTF1 ZDHHC2 ZNF372	Homo sapiens (human)
Type II Na+/Pi cotransporters	Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Sodium-dependent phosphate transport protein 2C	O95436 Q06495 Q8N130	NPT2 NPT2C NPTIIC SLC17A2 SLC34A1 SLC34A2 SLC34A3	Homo sapiens (human)
Defective SLC34A2 causes PALM	Sodium-dependent phosphate transport protein 2B	O95436	SLC34A2	Homo sapiens (human)
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM)	Sodium-dependent phosphate transport protein 2B	O95436	SLC34A2	Homo sapiens (human)
ATF4 activates genes in response to endoplasmic reticulum stress	Asparagine synthetase [glutamine-hydrolyzing] C-C motif chemokine 2 CCAAT/enhancer-binding protein beta CCAAT/enhancer-binding protein gamma Cyclic AMP-dependent transcription factor ATF-3 Cyclic AMP-dependent transcription factor ATF-4 Cyclic AMP-dependent transcription factor ATF-6 alpha DNA damage-inducible transcript 3 protein Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 Far upstream element-binding protein 2 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein Insulin-like growth factor-binding protein 1 Interleukin-8 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Poly(A)-specific ribonuclease PARN m7GpppN-mRNA hydrolase	O95453 P08243 P08833 P10145 P13500 P17676 P18847 P18848 P18850 P23511 P25208 P35638 P53567 Q06265 Q13868 Q13952 Q15011 Q15024 Q5RKV6 Q8IU60 Q92945 Q96B26 Q9NPD3 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2	ASNS ATF3 ATF4 ATF6 CCL2 CEBPB CEBPG CHOP CHOP10 CML28 CREB2 CSL4 CXCL8 DAN DCP2 DDIT3 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FUBP2 GADD153 HAP3 HERP HERPUD1 IBP1 IGFBP1 IL8 KHSRP KIAA0025 KIAA0116 KIAA1008 MCP1 MIF1 MTR3 NFYA NFYB NFYC NUDT20 OIP2 PARN PMSCL1 RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SCYA2 SKI6 TCF5 TS11 TXREB	Homo sapiens (human)
KSRP (KHSRP) binds and destabilizes mRNA	14-3-3 protein zeta/delta Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 Far upstream element-binding protein 2 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Poly(A)-specific ribonuclease PARN RAC-alpha serine/threonine-protein kinase m7GpppN-mRNA hydrolase	O95453 P31749 P63104 Q06265 Q13868 Q15024 Q15759 Q16539 Q5RKV6 Q8IU60 Q92945 Q96B26 Q9NPD3 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2	AKT1 CML28 CSBP CSBP1 CSBP2 CSL4 CSPB1 DAN DCP2 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FUBP2 KHSRP KIAA0116 KIAA1008 MAPK11 MAPK14 MTR3 MXI2 NUDT20 OIP2 PARN PKB PMSCL1 PRKM11 RAC RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SAPK2 SAPK2A SAPK2B SKI6 YWHAZ	Homo sapiens (human)
Depolymerization of the Nuclear Lamina	CTD nuclear envelope phosphatase 1 Cyclin-dependent kinase 1 Emerin G2/mitotic-specific cyclin-B1 Inner nuclear membrane protein Man1 LEM domain-containing protein 2 Lamin-B1 Nuclear envelope phosphatase-regulatory subunit 1 Phosphatidate phosphatase LPIN1 Phosphatidate phosphatase LPIN2 Phosphatidate phosphatase LPIN3 Protein kinase C alpha type Protein kinase C beta type	O95476 P05771 P06493 P14635 P17252 P20700 P50402 Q14693 Q8N9A8 Q8NC56 Q92539 Q9BQK8 Q9Y2U8	C16orf69 CCNB CCNB1 CDC2 CDC28A CDK1 CDKN1 CNEP1R1 CTDNEP1 DULLARD EDMD EMD KIAA0188 KIAA0249 LEMD2 LEMD3 LIPN3L LMN2 LMNB LMNB1 LPIN1 LPIN2 LPIN3 MAN1 P34CDC2 PKCA PKCB PRKACA PRKCA PRKCB PRKCB1 STA TMEM188	Homo sapiens (human)
HDL assembly	Alpha-2-macroglobulin Apolipoprotein A-I Palmitoyltransferase ZDHHC8 Phospholipid-transporting ATPase ABCA1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O95477 P01023 P02647 P17612 P22612 P22694 Q9ULC8	A2M ABC1 ABCA1 APOA1 CERP CPAMD5 KIAA1292 PKACA PRKACA PRKACB PRKACG ZDHHC8 ZDHHCL1 ZNF378	Homo sapiens (human)
Defective ABCA1 causes TGD	Apolipoprotein A-I Phospholipid-transporting ATPase ABCA1	O95477 P02647	ABC1 ABCA1 APOA1 CERP	Homo sapiens (human)

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